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The map label for this gene is 157963273

Identifier: 157963273

GI number: 157963273

Start: 4225881

End: 4227299

Strand: Direct

Name: 157963273

Synonym: Spea_3459

Alternate gene names: NA

Gene position: 4225881-4227299 (Clockwise)

Preceding gene: 157963272

Following gene: 157963280

Centisome position: 81.67

GC content: 38.2

Gene sequence:

>1419_bases
ATGCAATTAAGACAATGGCAATTAGAGTGCGTCAATCGCGCTCTAGAGCATTTTAATGCCAACCAAAGACACTTTCTCTG
CTTAGCAACTCCAGGGGCTGGAAAGACGATTATGGCAGCAGAGGTTGCAGCTGAGTTATTCGAACAAGATCTTATTGATT
TTGTATTATGCTTTTCGCCTTCTGTAAATATCTCGAAAGGCATTCAGAAAACATTCTCACATCGATTAGAGTGTCGCTTT
GATGGAGTAATAGGTGCAGTAGGTTGTTCTTACACATATCAAGGAATGCTATCTTTTAAAGAAGACTTTTGGCAGCTACT
AAAAAGGAATCGGGTATTGGTGATCTTTGATGAGATCCATCATTGTTCTGGCAGTACTCTTGAGGATGCGAATGCTTGGG
GAGAGGAGATCTTACTAAATATACAAGATCAAGCACAATACACCTTGGCATTGACTGGGACGCCTTGGCGCTCTGATCAA
GCCCCCATTGTTTTATCTCGATATCTAGACCCTGATAACGAAATTCAGTGTGATTATGTTTACGGCTTAAAAGAAGCTGT
GAGAGATGGTGTTTGTCGGAATCCTAAAATAGTATTAATTGATAACGAAGAGCTTTCAGTTAAAAATCAGTATAATGAAA
TCCAAACTTTCAGCAGTTTTAATGAGCTTTTTAAAGGTTCATCAATTCCGTATCAATTAGTCATCAAAAATGATTTAGCT
ATTCATCATGTTTTGAGCTTAGCAATTGATAAGCTAGGTAGCATTAGGCAATTGAACCCCGATGCAGCTGGTTTAGTGGT
CGCATCTTCAATCGAACATGCGTGCTTTATCTTAGAAATCCTCAAAAATACATTCAAACAAACAGCAACAATCGTAACTT
ATCAAGAAATTGCCCCGTCGGATACAATTAACAAGTTTCGGCATGATGATACACAATGGATTGTTAGTGTAGGAATGATT
AGCGAAGGTACTGATATTCCGAGGTTACAGGTTTGCTGCCATTTAAGTAGAGTAAAAACCGAATTATATTTTCGGCAAAT
ACTAGGTCGTATTTTACGAACAACTAAAGCACATGATCAACAAGCTTGGCTCTTCACTTTTGCAGAGCCCAAACTAACCG
ATTTTGCATATCGAATAGCGATTGAACTACCAGAAGGCTCAACTGTAATTAGAGAGAAGAAACCTAGAGGAAGTATGAAG
TTAACAATATCGAATAATTGTAAAATAACTAATGAACCTCCGAGCCTGCCAAGTTGTTTTACACTTAGTATGGGTGATGC
TATAGGTAGGAAACAGATTAATTCATTACCAAGTCAGGCAATTAATGATGCTCACTTAATCAGTTCAATGAACCCATCAA
TGCTGCTACTAGGCAGGTTTAGGGAGAAGGTCATTTCGACTTTTGATTCTCCATTTTAA

Upstream 100 bases:

>100_bases
TTGAGTCGCAGTACATGCTAGCTAGAGAAAGTAGCTCGAAGTTACTTGGTCAAATTAAAGCGATTAAATCGGTACTCTCG
CACCAACAGAAGTAACTCAA

Downstream 100 bases:

>100_bases
TACTTATTTATGGTGCATATACAAATAAGAATCAGTGTAATGGCCAGCTAAAACTGGCCACGGCTATATAGCATTTCTGA
GTTAGGAATTATACTGATTT

Product: type III restriction protein res subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MQLRQWQLECVNRALEHFNANQRHFLCLATPGAGKTIMAAEVAAELFEQDLIDFVLCFSPSVNISKGIQKTFSHRLECRF
DGVIGAVGCSYTYQGMLSFKEDFWQLLKRNRVLVIFDEIHHCSGSTLEDANAWGEEILLNIQDQAQYTLALTGTPWRSDQ
APIVLSRYLDPDNEIQCDYVYGLKEAVRDGVCRNPKIVLIDNEELSVKNQYNEIQTFSSFNELFKGSSIPYQLVIKNDLA
IHHVLSLAIDKLGSIRQLNPDAAGLVVASSIEHACFILEILKNTFKQTATIVTYQEIAPSDTINKFRHDDTQWIVSVGMI
SEGTDIPRLQVCCHLSRVKTELYFRQILGRILRTTKAHDQQAWLFTFAEPKLTDFAYRIAIELPEGSTVIREKKPRGSMK
LTISNNCKITNEPPSLPSCFTLSMGDAIGRKQINSLPSQAINDAHLISSMNPSMLLLGRFREKVISTFDSPF

Sequences:

>Translated_472_residues
MQLRQWQLECVNRALEHFNANQRHFLCLATPGAGKTIMAAEVAAELFEQDLIDFVLCFSPSVNISKGIQKTFSHRLECRF
DGVIGAVGCSYTYQGMLSFKEDFWQLLKRNRVLVIFDEIHHCSGSTLEDANAWGEEILLNIQDQAQYTLALTGTPWRSDQ
APIVLSRYLDPDNEIQCDYVYGLKEAVRDGVCRNPKIVLIDNEELSVKNQYNEIQTFSSFNELFKGSSIPYQLVIKNDLA
IHHVLSLAIDKLGSIRQLNPDAAGLVVASSIEHACFILEILKNTFKQTATIVTYQEIAPSDTINKFRHDDTQWIVSVGMI
SEGTDIPRLQVCCHLSRVKTELYFRQILGRILRTTKAHDQQAWLFTFAEPKLTDFAYRIAIELPEGSTVIREKKPRGSMK
LTISNNCKITNEPPSLPSCFTLSMGDAIGRKQINSLPSQAINDAHLISSMNPSMLLLGRFREKVISTFDSPF
>Mature_472_residues
MQLRQWQLECVNRALEHFNANQRHFLCLATPGAGKTIMAAEVAAELFEQDLIDFVLCFSPSVNISKGIQKTFSHRLECRF
DGVIGAVGCSYTYQGMLSFKEDFWQLLKRNRVLVIFDEIHHCSGSTLEDANAWGEEILLNIQDQAQYTLALTGTPWRSDQ
APIVLSRYLDPDNEIQCDYVYGLKEAVRDGVCRNPKIVLIDNEELSVKNQYNEIQTFSSFNELFKGSSIPYQLVIKNDLA
IHHVLSLAIDKLGSIRQLNPDAAGLVVASSIEHACFILEILKNTFKQTATIVTYQEIAPSDTINKFRHDDTQWIVSVGMI
SEGTDIPRLQVCCHLSRVKTELYFRQILGRILRTTKAHDQQAWLFTFAEPKLTDFAYRIAIELPEGSTVIREKKPRGSMK
LTISNNCKITNEPPSLPSCFTLSMGDAIGRKQINSLPSQAINDAHLISSMNPSMLLLGRFREKVISTFDSPF

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2917 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: NA

Molecular weight: Translated: 53318; Mature: 53318

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRQWQLECVNRALEHFNANQRHFLCLATPGAGKTIMAAEVAAELFEQDLIDFVLCFSP
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SVNISKGIQKTFSHRLECRFDGVIGAVGCSYTYQGMLSFKEDFWQLLKRNRVLVIFDEIH
CCCHHHHHHHHHHHHCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHH
HCSGSTLEDANAWGEEILLNIQDQAQYTLALTGTPWRSDQAPIVLSRYLDPDNEIQCDYV
CCCCCCCCHHHCCCHHEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEHH
YGLKEAVRDGVCRNPKIVLIDNEELSVKNQYNEIQTFSSFNELFKGSSIPYQLVIKNDLA
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHH
IHHVLSLAIDKLGSIRQLNPDAAGLVVASSIEHACFILEILKNTFKQTATIVTYQEIAPS
HHHHHHHHHHHCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCC
DTINKFRHDDTQWIVSVGMISEGTDIPRLQVCCHLSRVKTELYFRQILGRILRTTKAHDQ
HHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QAWLFTFAEPKLTDFAYRIAIELPEGSTVIREKKPRGSMKLTISNNCKITNEPPSLPSCF
CEEEEEECCCCCCCEEEEEEEECCCCCEEEECCCCCCCEEEEECCCCEECCCCCCCCCEE
TLSMGDAIGRKQINSLPSQAINDAHLISSMNPSMLLLGRFREKVISTFDSPF
EEECCCHHHHHHHHHCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLRQWQLECVNRALEHFNANQRHFLCLATPGAGKTIMAAEVAAELFEQDLIDFVLCFSP
CCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SVNISKGIQKTFSHRLECRFDGVIGAVGCSYTYQGMLSFKEDFWQLLKRNRVLVIFDEIH
CCCHHHHHHHHHHHHCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECHH
HCSGSTLEDANAWGEEILLNIQDQAQYTLALTGTPWRSDQAPIVLSRYLDPDNEIQCDYV
CCCCCCCCHHHCCCHHEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCCCCEEEEHH
YGLKEAVRDGVCRNPKIVLIDNEELSVKNQYNEIQTFSSFNELFKGSSIPYQLVIKNDLA
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHH
IHHVLSLAIDKLGSIRQLNPDAAGLVVASSIEHACFILEILKNTFKQTATIVTYQEIAPS
HHHHHHHHHHHCCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHEEEEEHHHCCC
DTINKFRHDDTQWIVSVGMISEGTDIPRLQVCCHLSRVKTELYFRQILGRILRTTKAHDQ
HHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QAWLFTFAEPKLTDFAYRIAIELPEGSTVIREKKPRGSMKLTISNNCKITNEPPSLPSCF
CEEEEEECCCCCCCEEEEEEEECCCCCEEEECCCCCCCEEEEECCCCEECCCCCCCCCEE
TLSMGDAIGRKQINSLPSQAINDAHLISSMNPSMLLLGRFREKVISTFDSPF
EEECCCHHHHHHHHHCHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]