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The map label for this gene is metH [H]

Identifier: 157963199

GI number: 157963199

Start: 4132917

End: 4136549

Strand: Direct

Name: metH [H]

Synonym: Spea_3384

Alternate gene names: 157963199

Gene position: 4132917-4136549 (Clockwise)

Preceding gene: 157963188

Following gene: 157963204

Centisome position: 79.87

GC content: 49.22

Gene sequence:

>3633_bases
ATGGGCACCATGATCCAAGACCGTAAGTTTGAAGAGCTGGATTTTCGGGGCCAGCAGTTCAAAGACTGGCATTGCGATGT
AAAGGGCAACAACGACATGTTGGTGCTTACTCAGCCTGAAGCCATCAAGCAGATCCATAAAGACTACCTATTAGCTGGCT
CAGACATCATCGAGACCAACACCTTTAATGCTACCCGTATCGCGATGGCTGACTACGACATGCAGGCGCATTCGGCTGAG
ATTAACCTTGTGGGTGCACGACTCGCCCGCGAAGCGGCTAACGAAGTTGAAGCTGAAACTGGCCGTCAGTGTTATGTCGC
GGGTGTACTGGGACCAACCAACCGCACCTGCTCTATCAGTCCAGATGTGAACGACCCGGGTTTTCGTAACGTCAGCTTCG
ATGAGCTGGTTGAGGCCTATATAGAGTCAATCAACGCCCTAGTTGCTGGCGGCAGCGATATCATCATGGTGGAAACCATT
TTTGATACCCTAAACGCCAAAGCCGCGCTGTTCGCAATTGAAACCGTATATGACACTCAAGGTTTCCGCCTGCCAATTAT
GATCTCTGGCACTATCACCGATGCCTCAGGCCGTACACTTACCGGACAGACAACCGAAGCCTTCTATAACTCACTGCGTC
ACGTTAAGCCGCTATCTATCGGTCTTAACTGTGCATTAGGGCCAAAAGAGCTGCGCCCTTATGTGGAAGAGCTGTCTAAA
ATTTCCGAATGCTATGTGTCGGCACACCCGAATGCGGGCCTACCCAATGAATTTGGTGGTTACGACGAAACGCCAGAGCA
AATGGCGGAAATCATCGAAGAGTGGGCACAAGAAGGATTCTTAAACATTATTGGTGGCTGTTGTGGTACCACGCCTGATC
ATATTCGGGTCATTCGCGAAGCCGTGATCAAACATTCAGCACGTCCATTACCCGATATTCCAGTAGCTTGTCGCCTATCA
GGGCTTGAACCTCTGACCATAGATGAGAACTCGCTATTTTTAAACGTCGGCGAACGTACCAACGTTACGGGGTCGGCGAA
GTTTTTACGCCTAATCAAAACCGGCGAATATGAAGAAGCGTTATCAGTTGCTCGCGAGCAAGTGGAGAACGGCGCACAGA
TCATCGATATCAACATGGATGAAGGCATGCTCGACGGCGCCGAAACCATGCATAAATTCCTCAACCTAATCGCCTCAGAG
CCCGATATCTCACGGGTACCTATCATGATCGACTCCTCTAAGTGGGAAGTGATTGAGGCTGGCCTTAAATGCATTCAAGG
TAAAGGCATCGTTAACTCAATTTCGCTTAAAGAAGGCGAAGAGAAGTTTATCGAGCAAGCCAAACTCGTTAAACGCTACG
GCGCCGCGGCAATTGTGATGGCGTTTGATGAAGTTGGCCAAGCCGATACCAAAGCGCGTAAAGTTGAGATCTGTACCCGC
GCCTACAATGTGTTAGTCGATAAAGTCGGCTTTCCACCAGAAGACATTATCTTCGACCCCAACATCTTTGCTATTGCCAC
CGGTATCGAGGAGCACGACAACTATGCGGTTGACTTTATCGAAGCCACCGCAGAGATAAAACGTACCCTACCCCATGCAA
TGATCTCTGGCGGTGTATCTAACGTGTCATTCTCTTTCCGTGGAAACAACCCGGTACGAGAAGCGATTCACGCCGTGTTC
CTGTACCACGCGATTCAAGCTGGCATGGACATGGGTATTGTTAACGCTGGGCAATTGGCGATTTATGATGACATCGACCC
AGAGCTTAAGGAAAGAGTCGAAGCCATAGTCCAGAACTTGCCCTGCAAAGTAGCCGATACCAATAACACCGAACTGCTAT
TAGAAGTCGCAGAAAAGTTCCGCGGTGACGGCAGCCAAACCGCCAAAAAAGAAGATTTAGAGTGGCGCAGTAAACCTGTT
AATGAGCGTTTAGCGCACGCGCTAGTGAAAGGCATTACCGAATTTATCGATGAGGATACCGAAGAAGCGCGGCAACAAGC
CACACGCCCACTCGATGTGATTGAAGGTCCATTGATGGATGGCATGAACATAGTGGGTGACCTATTTGGCTCGGGTAAGA
TGTTCCTGCCTCAGGTGGTAAAATCAGCCCGCGTGATGAAAAAAGCCGTGGCCTACTTAAACCCCTATATTGAGCTTGAG
AAAGTCGCTGGTCAGTCTAACGGTAAAATATTAATGGTTACCGTTAAGGGAGATGTACACGATATCGGTAAAAATATTGT
CGGCGTGGTTTTAGCTTGTAACGGCTATGAAGTCATCGATTTGGGCGTAATGGTACCGGTTGAGAAAATCATCGAAGTCG
CTATTGCAGAAAATGTCGATATTATCGGCATGTCAGGGCTTATCACCCCAAGCCTAGATGAGATGGTACATAACGTTAAG
AGTTTCCATAAGGCTGGGTTAACCATCCCGTCGATTATTGGCGGTGCCACCTGCTCTAAAATTCATACCGCAGTCAAGAT
TGCCCCTCATTCACCTGAAGGTGCCATCTATATTGCCGATGCATCACGCGCCGTGCCCATGGTGTCGAAACTGATCAACG
ATGCAACCCGCCAAGCGACTATCGACCAAGCCTATGCAGAATACGATGTTATGCGCGAGAAACGTCTGTCACAGACTAAA
CGTAAGGTGATTACTTCGATTGCAGCCGCACGTGAAAACAGTTGCCAACACGACTGGCAAAACTACACGCCATTTGTGCC
AAATCAGCTAGGGCGTCAGGTATTTGATGACTACCCACTTGAAGATTTAGTCGAGCGCATCGACTGGACCCCCTTCTTTA
GAAGCTGGGAATTACATGGCCATTTCCCGCGAATTTTAGAAGATGAAGTCGTAGGTATTGAGGCGCGAAAACTGTTTAGC
GATGGCAAAGCCATGCTGGATAAAATCATCAGTGAAAAATGGCTTACCGCCAAGGCTGTGATTGGCTTATTCCCAGCCAA
CACTGTTAACCATGACGATATAGAGCTTTACACTGATGAGACTCGTAGCGAGCTTGAACTCACGACTCATCACCTGCGGA
TGCAGATTGAGCGTGTCGGTAATGACAACTTCTGTTTAGCAGACTTTGTTGCGCCAAAAAATAGTGGTGTTGCCGATTAC
ATGGGCGGCTTTGCGGTAACCGCTGGCCATGGCATTGACGAGCATGTGGCTCGCTTTGAAGCCGACCATGACGACTACAG
CGCGATTATGCTCAAATGCTTAGCCGATCGTTTAGCCGAAGCCTTTGCCGAGCGTATGCATGAAAGGGTACGTAAAGAGT
TTTGGGGATATGCATCTGATGAGGTACTCGATAACGAGGCGCTGATTCGGGAGAAGTACAAAGGCATACGTCCGGCACCG
GGCTACCCCGCTTGCCCAGATCACACAGAGAAAGGGCTGCTTTGGGACTTACTCAAGCCTGATGAAACCATCGGCCTTAA
GATCACCGAAAGCTACGCCATGTTCCCAACGGCAGCGGTTTCAGGTTGGTACTTTGCCCATCCTAAATCGCGGTACTTTG
GTGTGACCAACATAGGTCGCGATCAAGTAGAAGATTATGCGACACGTAAAGGCATGAGCATCGAGGAGACCGAGCGCTGG
CTAGCTCCAGTGCTAGACTACGATCCACAATAG

Upstream 100 bases:

>100_bases
TGCCTTGAGCGCGGTAGCACATACTCCAGACACTGCCGACAAGGTTTTAGCTGTCCTTACCCAAAAGCTTCAGGATGGGA
TCCTTATCCTAGACGGCGCT

Downstream 100 bases:

>100_bases
TGCGCGAAAGCTGCTTGCTGCCCGGTTTCTGCAAATCTAAAGATGGACGATTCTAGGACGAGGCAGAGCTAATAAAAAAG
CCACACTTTCAAAAAGTGTG

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1210; Mature: 1209

Protein sequence:

>1210_residues
MGTMIQDRKFEELDFRGQQFKDWHCDVKGNNDMLVLTQPEAIKQIHKDYLLAGSDIIETNTFNATRIAMADYDMQAHSAE
INLVGARLAREAANEVEAETGRQCYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYIESINALVAGGSDIIMVETI
FDTLNAKAALFAIETVYDTQGFRLPIMISGTITDASGRTLTGQTTEAFYNSLRHVKPLSIGLNCALGPKELRPYVEELSK
ISECYVSAHPNAGLPNEFGGYDETPEQMAEIIEEWAQEGFLNIIGGCCGTTPDHIRVIREAVIKHSARPLPDIPVACRLS
GLEPLTIDENSLFLNVGERTNVTGSAKFLRLIKTGEYEEALSVAREQVENGAQIIDINMDEGMLDGAETMHKFLNLIASE
PDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEKFIEQAKLVKRYGAAAIVMAFDEVGQADTKARKVEICTR
AYNVLVDKVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATAEIKRTLPHAMISGGVSNVSFSFRGNNPVREAIHAVF
LYHAIQAGMDMGIVNAGQLAIYDDIDPELKERVEAIVQNLPCKVADTNNTELLLEVAEKFRGDGSQTAKKEDLEWRSKPV
NERLAHALVKGITEFIDEDTEEARQQATRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELE
KVAGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMVPVEKIIEVAIAENVDIIGMSGLITPSLDEMVHNVK
SFHKAGLTIPSIIGGATCSKIHTAVKIAPHSPEGAIYIADASRAVPMVSKLINDATRQATIDQAYAEYDVMREKRLSQTK
RKVITSIAAARENSCQHDWQNYTPFVPNQLGRQVFDDYPLEDLVERIDWTPFFRSWELHGHFPRILEDEVVGIEARKLFS
DGKAMLDKIISEKWLTAKAVIGLFPANTVNHDDIELYTDETRSELELTTHHLRMQIERVGNDNFCLADFVAPKNSGVADY
MGGFAVTAGHGIDEHVARFEADHDDYSAIMLKCLADRLAEAFAERMHERVRKEFWGYASDEVLDNEALIREKYKGIRPAP
GYPACPDHTEKGLLWDLLKPDETIGLKITESYAMFPTAAVSGWYFAHPKSRYFGVTNIGRDQVEDYATRKGMSIEETERW
LAPVLDYDPQ

Sequences:

>Translated_1210_residues
MGTMIQDRKFEELDFRGQQFKDWHCDVKGNNDMLVLTQPEAIKQIHKDYLLAGSDIIETNTFNATRIAMADYDMQAHSAE
INLVGARLAREAANEVEAETGRQCYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYIESINALVAGGSDIIMVETI
FDTLNAKAALFAIETVYDTQGFRLPIMISGTITDASGRTLTGQTTEAFYNSLRHVKPLSIGLNCALGPKELRPYVEELSK
ISECYVSAHPNAGLPNEFGGYDETPEQMAEIIEEWAQEGFLNIIGGCCGTTPDHIRVIREAVIKHSARPLPDIPVACRLS
GLEPLTIDENSLFLNVGERTNVTGSAKFLRLIKTGEYEEALSVAREQVENGAQIIDINMDEGMLDGAETMHKFLNLIASE
PDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEKFIEQAKLVKRYGAAAIVMAFDEVGQADTKARKVEICTR
AYNVLVDKVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATAEIKRTLPHAMISGGVSNVSFSFRGNNPVREAIHAVF
LYHAIQAGMDMGIVNAGQLAIYDDIDPELKERVEAIVQNLPCKVADTNNTELLLEVAEKFRGDGSQTAKKEDLEWRSKPV
NERLAHALVKGITEFIDEDTEEARQQATRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELE
KVAGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMVPVEKIIEVAIAENVDIIGMSGLITPSLDEMVHNVK
SFHKAGLTIPSIIGGATCSKIHTAVKIAPHSPEGAIYIADASRAVPMVSKLINDATRQATIDQAYAEYDVMREKRLSQTK
RKVITSIAAARENSCQHDWQNYTPFVPNQLGRQVFDDYPLEDLVERIDWTPFFRSWELHGHFPRILEDEVVGIEARKLFS
DGKAMLDKIISEKWLTAKAVIGLFPANTVNHDDIELYTDETRSELELTTHHLRMQIERVGNDNFCLADFVAPKNSGVADY
MGGFAVTAGHGIDEHVARFEADHDDYSAIMLKCLADRLAEAFAERMHERVRKEFWGYASDEVLDNEALIREKYKGIRPAP
GYPACPDHTEKGLLWDLLKPDETIGLKITESYAMFPTAAVSGWYFAHPKSRYFGVTNIGRDQVEDYATRKGMSIEETERW
LAPVLDYDPQ
>Mature_1209_residues
GTMIQDRKFEELDFRGQQFKDWHCDVKGNNDMLVLTQPEAIKQIHKDYLLAGSDIIETNTFNATRIAMADYDMQAHSAEI
NLVGARLAREAANEVEAETGRQCYVAGVLGPTNRTCSISPDVNDPGFRNVSFDELVEAYIESINALVAGGSDIIMVETIF
DTLNAKAALFAIETVYDTQGFRLPIMISGTITDASGRTLTGQTTEAFYNSLRHVKPLSIGLNCALGPKELRPYVEELSKI
SECYVSAHPNAGLPNEFGGYDETPEQMAEIIEEWAQEGFLNIIGGCCGTTPDHIRVIREAVIKHSARPLPDIPVACRLSG
LEPLTIDENSLFLNVGERTNVTGSAKFLRLIKTGEYEEALSVAREQVENGAQIIDINMDEGMLDGAETMHKFLNLIASEP
DISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEKFIEQAKLVKRYGAAAIVMAFDEVGQADTKARKVEICTRA
YNVLVDKVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATAEIKRTLPHAMISGGVSNVSFSFRGNNPVREAIHAVFL
YHAIQAGMDMGIVNAGQLAIYDDIDPELKERVEAIVQNLPCKVADTNNTELLLEVAEKFRGDGSQTAKKEDLEWRSKPVN
ERLAHALVKGITEFIDEDTEEARQQATRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEK
VAGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMVPVEKIIEVAIAENVDIIGMSGLITPSLDEMVHNVKS
FHKAGLTIPSIIGGATCSKIHTAVKIAPHSPEGAIYIADASRAVPMVSKLINDATRQATIDQAYAEYDVMREKRLSQTKR
KVITSIAAARENSCQHDWQNYTPFVPNQLGRQVFDDYPLEDLVERIDWTPFFRSWELHGHFPRILEDEVVGIEARKLFSD
GKAMLDKIISEKWLTAKAVIGLFPANTVNHDDIELYTDETRSELELTTHHLRMQIERVGNDNFCLADFVAPKNSGVADYM
GGFAVTAGHGIDEHVARFEADHDDYSAIMLKCLADRLAEAFAERMHERVRKEFWGYASDEVLDNEALIREKYKGIRPAPG
YPACPDHTEKGLLWDLLKPDETIGLKITESYAMFPTAAVSGWYFAHPKSRYFGVTNIGRDQVEDYATRKGMSIEETERWL
APVLDYDPQ

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1236, Percent_Identity=53.8834951456311, Blast_Score=1309, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1210, Percent_Identity=65.7851239669422, Blast_Score=1626, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1232, Percent_Identity=52.1915584415584, Blast_Score=1261, Evalue=0.0,
Organism=Drosophila melanogaster, GI24585077, Length=292, Percent_Identity=25.3424657534247, Blast_Score=76, Evalue=2e-13,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 134127; Mature: 133996

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTMIQDRKFEELDFRGQQFKDWHCDVKGNNDMLVLTQPEAIKQIHKDYLLAGSDIIETN
CCCCCCCCCCHHHCCCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEECC
TFNATRIAMADYDMQAHSAEINLVGARLAREAANEVEAETGRQCYVAGVLGPTNRTCSIS
CCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEC
PDVNDPGFRNVSFDELVEAYIESINALVAGGSDIIMVETIFDTLNAKAALFAIETVYDTQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHCCCCCEEEEEHHCCCC
GFRLPIMISGTITDASGRTLTGQTTEAFYNSLRHVKPLSIGLNCALGPKELRPYVEELSK
CCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH
ISECYVSAHPNAGLPNEFGGYDETPEQMAEIIEEWAQEGFLNIIGGCCGTTPDHIRVIRE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
AVIKHSARPLPDIPVACRLSGLEPLTIDENSLFLNVGERTNVTGSAKFLRLIKTGEYEEA
HHHHHCCCCCCCCCHHEEECCCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHCCCHHHH
LSVAREQVENGAQIIDINMDEGMLDGAETMHKFLNLIASEPDISRVPIMIDSSKWEVIEA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHH
GLKCIQGKGIVNSISLKEGEEKFIEQAKLVKRYGAAAIVMAFDEVGQADTKARKVEICTR
HHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHH
AYNVLVDKVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATAEIKRTLPHAMISGGVS
HHHHHHHHCCCCCHHEEECCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NVSFSFRGNNPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPELKERVEAIVQNL
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHC
PCKVADTNNTELLLEVAEKFRGDGSQTAKKEDLEWRSKPVNERLAHALVKGITEFIDEDT
CEEEECCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHCCCHHHHHHHHHHHHHHHHHCCCH
EEARQQATRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELE
HHHHHHHCCCHHHHCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
KVAGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMVPVEKIIEVAIAENVD
HHCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCEEEEECHHHHHHHHHHHHHHCCCC
IIGMSGLITPSLDEMVHNVKSFHKAGLTIPSIIGGATCSKIHTAVKIAPHSPEGAIYIAD
EEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHEEEECCCCCCCEEEEEC
ASRAVPMVSKLINDATRQATIDQAYAEYDVMREKRLSQTKRKVITSIAAARENSCQHDWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
NYTPFVPNQLGRQVFDDYPLEDLVERIDWTPFFRSWELHGHFPRILEDEVVGIEARKLFS
CCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
DGKAMLDKIISEKWLTAKAVIGLFPANTVNHDDIELYTDETRSELELTTHHLRMQIERVG
CCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
NDNFCLADFVAPKNSGVADYMGGFAVTAGHGIDEHVARFEADHDDYSAIMLKCLADRLAE
CCCEEEEEECCCCCCCHHHHHCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AFAERMHERVRKEFWGYASDEVLDNEALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKP
HHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCC
DETIGLKITESYAMFPTAAVSGWYFAHPKSRYFGVTNIGRDQVEDYATRKGMSIEETERW
CCCEEEEEECCHHHCCHHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHH
LAPVLDYDPQ
HHHHHCCCCC
>Mature Secondary Structure 
GTMIQDRKFEELDFRGQQFKDWHCDVKGNNDMLVLTQPEAIKQIHKDYLLAGSDIIETN
CCCCCCCCCHHHCCCCCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCEEECC
TFNATRIAMADYDMQAHSAEINLVGARLAREAANEVEAETGRQCYVAGVLGPTNRTCSIS
CCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEC
PDVNDPGFRNVSFDELVEAYIESINALVAGGSDIIMVETIFDTLNAKAALFAIETVYDTQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCCEEEHHHHHHHHCCCCCEEEEEHHCCCC
GFRLPIMISGTITDASGRTLTGQTTEAFYNSLRHVKPLSIGLNCALGPKELRPYVEELSK
CCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHH
ISECYVSAHPNAGLPNEFGGYDETPEQMAEIIEEWAQEGFLNIIGGCCGTTPDHIRVIRE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
AVIKHSARPLPDIPVACRLSGLEPLTIDENSLFLNVGERTNVTGSAKFLRLIKTGEYEEA
HHHHHCCCCCCCCCHHEEECCCCCEEECCCCEEEECCCCCCCCCHHHHHHHHHCCCHHHH
LSVAREQVENGAQIIDINMDEGMLDGAETMHKFLNLIASEPDISRVPIMIDSSKWEVIEA
HHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHH
GLKCIQGKGIVNSISLKEGEEKFIEQAKLVKRYGAAAIVMAFDEVGQADTKARKVEICTR
HHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHH
AYNVLVDKVGFPPEDIIFDPNIFAIATGIEEHDNYAVDFIEATAEIKRTLPHAMISGGVS
HHHHHHHHCCCCCHHEEECCCEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
NVSFSFRGNNPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPELKERVEAIVQNL
CEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHC
PCKVADTNNTELLLEVAEKFRGDGSQTAKKEDLEWRSKPVNERLAHALVKGITEFIDEDT
CEEEECCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHCCCHHHHHHHHHHHHHHHHHCCCH
EEARQQATRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELE
HHHHHHHCCCHHHHCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
KVAGQSNGKILMVTVKGDVHDIGKNIVGVVLACNGYEVIDLGVMVPVEKIIEVAIAENVD
HHCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCEEEEECHHHHHHHHHHHHHHCCCC
IIGMSGLITPSLDEMVHNVKSFHKAGLTIPSIIGGATCSKIHTAVKIAPHSPEGAIYIAD
EEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHEEEECCCCCCCEEEEEC
ASRAVPMVSKLINDATRQATIDQAYAEYDVMREKRLSQTKRKVITSIAAARENSCQHDWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHC
NYTPFVPNQLGRQVFDDYPLEDLVERIDWTPFFRSWELHGHFPRILEDEVVGIEARKLFS
CCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
DGKAMLDKIISEKWLTAKAVIGLFPANTVNHDDIELYTDETRSELELTTHHLRMQIERVG
CCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCC
NDNFCLADFVAPKNSGVADYMGGFAVTAGHGIDEHVARFEADHDDYSAIMLKCLADRLAE
CCCEEEEEECCCCCCCHHHHHCCEEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AFAERMHERVRKEFWGYASDEVLDNEALIREKYKGIRPAPGYPACPDHTEKGLLWDLLKP
HHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCC
DETIGLKITESYAMFPTAAVSGWYFAHPKSRYFGVTNIGRDQVEDYATRKGMSIEETERW
CCCEEEEEECCHHHCCHHHHCCEEEECCCCCEECCCCCCHHHHHHHHHHCCCCHHHHHHH
LAPVLDYDPQ
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]