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The map label for this gene is sigW [H]

Identifier: 157962988

GI number: 157962988

Start: 3885702

End: 3886247

Strand: Direct

Name: sigW [H]

Synonym: Spea_3171

Alternate gene names: 157962988

Gene position: 3885702-3886247 (Clockwise)

Preceding gene: 157962987

Following gene: 157962989

Centisome position: 75.09

GC content: 49.82

Gene sequence:

>546_bases
ATGGAGCCAAGGCCGCTTCTAGAACCTGAACTAATAGATAAAGCCAAGCTAGGTGACAAGCTCGCTTTCAAGCAACTGTA
TCAACTGCATCATCAGCGCGTATACGCACTGTGTTTGAGGATCACCGGCCAGGTATCACTGGCCGAGGAAGCGACACAGG
ACTGCTTCGTCAGGCTTTGGCAGAAGCTGCCCCAGTTTCGTGGTGAGAGTCAATTCACCACTTGGCTGCACAGTCTGAGT
GTCAACCAAGCCCTATCTAGCCTGAAGAAGCACCGCTCCTTTTGGTCACGATTTGTGAGTAGTGATACCGATGTTGAAAG
TATCAGCGATGAGTATGAAGACTTAGATAAGATTTTACTCAAGCTGCCTGAGCGAGCCCGGATCGTTTTCGTACTGCATG
CGCTCGAAGGCTACAAACACCAAGAGGTGGGGCAACTTATGGGCATTGCAGCAGGCACGAGTAAGGCGCAATACCACAGG
GCACAAAAGTTACTCGAAGCACTTATAGATCAAGGCCAAGTCGATATAGGAGGCCGTAATGAATGA

Upstream 100 bases:

>100_bases
AAATAATTTCTATTGCATTTAAACCTTTTTATCTGTTGGCTATGTCTTATTGGTATCGAAAGCGCACAAGGAATATTGAG
TGACGGCACAAATAAGGGTA

Downstream 100 bases:

>100_bases
TGCTAACGCAAAACTGACCCAATTAATTAATCAGGCACCTAAAGCAATCGTGCCACAAAAAGATCTGTGGCACGACATTG
AGCGACAGCTCGATAAGCCT

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MEPRPLLEPELIDKAKLGDKLAFKQLYQLHHQRVYALCLRITGQVSLAEEATQDCFVRLWQKLPQFRGESQFTTWLHSLS
VNQALSSLKKHRSFWSRFVSSDTDVESISDEYEDLDKILLKLPERARIVFVLHALEGYKHQEVGQLMGIAAGTSKAQYHR
AQKLLEALIDQGQVDIGGRNE

Sequences:

>Translated_181_residues
MEPRPLLEPELIDKAKLGDKLAFKQLYQLHHQRVYALCLRITGQVSLAEEATQDCFVRLWQKLPQFRGESQFTTWLHSLS
VNQALSSLKKHRSFWSRFVSSDTDVESISDEYEDLDKILLKLPERARIVFVLHALEGYKHQEVGQLMGIAAGTSKAQYHR
AQKLLEALIDQGQVDIGGRNE
>Mature_181_residues
MEPRPLLEPELIDKAKLGDKLAFKQLYQLHHQRVYALCLRITGQVSLAEEATQDCFVRLWQKLPQFRGESQFTTWLHSLS
VNQALSSLKKHRSFWSRFVSSDTDVESISDEYEDLDKILLKLPERARIVFVLHALEGYKHQEVGQLMGIAAGTSKAQYHR
AQKLLEALIDQGQVDIGGRNE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=179, Percent_Identity=27.3743016759777, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20774; Mature: 20774

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRPLLEPELIDKAKLGDKLAFKQLYQLHHQRVYALCLRITGQVSLAEEATQDCFVRLW
CCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QKLPQFRGESQFTTWLHSLSVNQALSSLKKHRSFWSRFVSSDTDVESISDEYEDLDKILL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KLPERARIVFVLHALEGYKHQEVGQLMGIAAGTSKAQYHRAQKLLEALIDQGQVDIGGRN
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
E
C
>Mature Secondary Structure
MEPRPLLEPELIDKAKLGDKLAFKQLYQLHHQRVYALCLRITGQVSLAEEATQDCFVRLW
CCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QKLPQFRGESQFTTWLHSLSVNQALSSLKKHRSFWSRFVSSDTDVESISDEYEDLDKILL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
KLPERARIVFVLHALEGYKHQEVGQLMGIAAGTSKAQYHRAQKLLEALIDQGQVDIGGRN
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]