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The map label for this gene is lutA [H]

Identifier: 157962814

GI number: 157962814

Start: 3671949

End: 3672692

Strand: Direct

Name: lutA [H]

Synonym: Spea_2996

Alternate gene names: 157962814

Gene position: 3671949-3672692 (Clockwise)

Preceding gene: 157962813

Following gene: 157962815

Centisome position: 70.96

GC content: 49.06

Gene sequence:

>744_bases
ATGAAGATTGCACTTTTCATTCCGTGTCTAGTGAATCAGATGGTCCCAGAAGTGGGAATAGCCACCTTAGAATTATTAGA
AAAGCTCGGACACCAAGTCATACTGCCAAAAGGCCAAACATGCTGCGGCCAGCCAATGACCAACTCAGGTTGCTATAACG
AAGCCAAGAAGACCACTATGAAATTGCTTAATGCCTTTAAGGGCGTTGAGTGTGATGCCATAGTGTGCCCAGCCGCTTCA
TGCCTTGTAGCCGCTAAAGAGAACTTTCACGAGTTTGATACAAGCTCTGAGGCTCAAGCTGTTATCGACAAGCTATATGA
GTTAACTGAGTTTCTGCACGACGTCTCGCCTATTCCAGCATTTACTAAGCCTTTTCCCCACAAGATCAGTCTACAGATGA
GCTGTCATGGCATTCGCATGCTAGATCTGGCCACCCCAAGTGAGCAGATGGGCCCACGGATGAACAAGTTCGAAGCTGTA
CTTGCATCTATCCCCGAAATTGAAATTGTCTATCCAGAGCGCCGCGATGAATGCTGTGGTTTCGGTGGTACCTTCGCCCT
AGATGAAGGCGCTGTCTCGGCTAAGATGGGCAAAGATAAAGCTCAGGCTCACGCCGAAACGGGCGCAGCTTATGCGGTTG
GCTTCGATCCCTCTTGCCTGCTGCACATCGATGGTATGGTCAGACGACAGAAACTGCCAATTGAGACTCGTCATATCGCC
CAAGTTATCAACGCAGCGCTTTAG

Upstream 100 bases:

>100_bases
CCGCTTACTAAAAAGTCGGCTTTTTAAGCAGACTTTTTGCGGCTACTTTTTACAATTAGAAAGTCGCTAACAATGTCTGC
AAAATAGAAGAGAAAACACA

Downstream 100 bases:

>100_bases
GAGAAGATATGTCCACCTCTAATTCAGCGGTACACGCCCATAAGGCGGAGATCTTCTGTAAAGATGAATCCCGCGTTGAT
TGGCACTCTAAAGCCCTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKIALFIPCLVNQMVPEVGIATLELLEKLGHQVILPKGQTCCGQPMTNSGCYNEAKKTTMKLLNAFKGVECDAIVCPAAS
CLVAAKENFHEFDTSSEAQAVIDKLYELTEFLHDVSPIPAFTKPFPHKISLQMSCHGIRMLDLATPSEQMGPRMNKFEAV
LASIPEIEIVYPERRDECCGFGGTFALDEGAVSAKMGKDKAQAHAETGAAYAVGFDPSCLLHIDGMVRRQKLPIETRHIA
QVINAAL

Sequences:

>Translated_247_residues
MKIALFIPCLVNQMVPEVGIATLELLEKLGHQVILPKGQTCCGQPMTNSGCYNEAKKTTMKLLNAFKGVECDAIVCPAAS
CLVAAKENFHEFDTSSEAQAVIDKLYELTEFLHDVSPIPAFTKPFPHKISLQMSCHGIRMLDLATPSEQMGPRMNKFEAV
LASIPEIEIVYPERRDECCGFGGTFALDEGAVSAKMGKDKAQAHAETGAAYAVGFDPSCLLHIDGMVRRQKLPIETRHIA
QVINAAL
>Mature_247_residues
MKIALFIPCLVNQMVPEVGIATLELLEKLGHQVILPKGQTCCGQPMTNSGCYNEAKKTTMKLLNAFKGVECDAIVCPAAS
CLVAAKENFHEFDTSSEAQAVIDKLYELTEFLHDVSPIPAFTKPFPHKISLQMSCHGIRMLDLATPSEQMGPRMNKFEAV
LASIPEIEIVYPERRDECCGFGGTFALDEGAVSAKMGKDKAQAHAETGAAYAVGFDPSCLLHIDGMVRRQKLPIETRHIA
QVINAAL

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=247, Percent_Identity=29.9595141700405, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788576, Length=232, Percent_Identity=23.2758620689655, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 26909; Mature: 26909

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIALFIPCLVNQMVPEVGIATLELLEKLGHQVILPKGQTCCGQPMTNSGCYNEAKKTTM
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
KLLNAFKGVECDAIVCPAASCLVAAKENFHEFDTSSEAQAVIDKLYELTEFLHDVSPIPA
HHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
FTKPFPHKISLQMSCHGIRMLDLATPSEQMGPRMNKFEAVLASIPEIEIVYPERRDECCG
CCCCCCCEEEEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHCCCCEEEECCCCCHHHCC
FGGTFALDEGAVSAKMGKDKAQAHAETGAAYAVGFDPSCLLHIDGMVRRQKLPIETRHIA
CCCCEEECCCCHHHHCCCHHHHHHHHCCCEEEECCCCCEEEEECHHHHHHCCCCHHHHHH
QVINAAL
HHHHHCC
>Mature Secondary Structure
MKIALFIPCLVNQMVPEVGIATLELLEKLGHQVILPKGQTCCGQPMTNSGCYNEAKKTTM
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
KLLNAFKGVECDAIVCPAASCLVAAKENFHEFDTSSEAQAVIDKLYELTEFLHDVSPIPA
HHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
FTKPFPHKISLQMSCHGIRMLDLATPSEQMGPRMNKFEAVLASIPEIEIVYPERRDECCG
CCCCCCCEEEEEEECCCEEEEEECCCHHHHCCCHHHHHHHHHCCCCEEEECCCCCHHHCC
FGGTFALDEGAVSAKMGKDKAQAHAETGAAYAVGFDPSCLLHIDGMVRRQKLPIETRHIA
CCCCEEECCCCHHHHCCCHHHHHHHHCCCEEEECCCCCEEEEECHHHHHHCCCCHHHHHH
QVINAAL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]