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The map label for this gene is xni

Identifier: 157962794

GI number: 157962794

Start: 3647092

End: 3647862

Strand: Direct

Name: xni

Synonym: Spea_2976

Alternate gene names: 157962794

Gene position: 3647092-3647862 (Clockwise)

Preceding gene: 157962793

Following gene: 157962795

Centisome position: 70.48

GC content: 46.43

Gene sequence:

>771_bases
ATGAATAAACTGCTAATTATCGATGGCATGAACTTAGTGCGGCGCATCCACGCCGCACAGCCTAACGAATCTGATATCAC
AGGACTGAAAGAACGTGTTCATGGTGCCTGTCGCAAACTACTTAAATATCATATACCAACACACGCAGCTATCGTATGGG
ATGGTGATGCAATCTCATGGCGAAAAACACTATTCCCTGACTACAAAAAAGGCCGTAAGCCCATGCCTGAAGCCTTGGCA
AACGGCCTCAATGACATCAAAGCTTATCTAGCGGAGCATCATATCCACTCAGTCGATGCCGACTCCGAAGCGGACGACGT
TATCGCCACCTTGGCAACAAAGCTGGTTAACATTGATGGCGAAGCCATTATCGTCTCAACAGACAAAGGTTTTAGCCAAT
TAAATCATCCAAAGATCAAGCTGTGGGATCACTTCAATCAAACCTACCTGACGATTGAAGAGATGGAGAAAAAGCTAGGC
ATCGAGCGCAGCCAATTAATTGATTACCTTGCACTCGCGGGGGATAGTGGCAATAAAATTCCAGGCGTTCCCGGGATCGG
GCCAAAGTCCGCCGTTGAGTTGCTGAGAATATATCGCTCTCTCGCAAGCATCTATAACTCTATCGACAAGGTAGGCGCTA
AGCAGGCTAAAAAACTTGAAGCGGGTAAGCAGATGGCGCGCCTAAGCTATAAACTGGTTCAACTTAAAACCGATATGCCC
CTAAGCGTCAACTTAAAGCAGTTTAGGATAAAAAAGCCGGATTCCGAATGA

Upstream 100 bases:

>100_bases
TCCGCATCGCACAGCAAAACGAACTGGTGTTACAGGTGAGCGAGTTCGTTCCCTGTTATGAAAGTTATCAAGTAGAAAGT
GGAAAGTCATAGAGTATTAA

Downstream 100 bases:

>100_bases
GCTTACATTTGTTAACACAAAGTTGCTGCTCAAGCATTTACCATTGCTTTACCAAATAGTATCTTAAGGTTTTCGAAAGA
ACAGTATGAAGGAAGCATTG

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNKLLIIDGMNLVRRIHAAQPNESDITGLKERVHGACRKLLKYHIPTHAAIVWDGDAISWRKTLFPDYKKGRKPMPEALA
NGLNDIKAYLAEHHIHSVDADSEADDVIATLATKLVNIDGEAIIVSTDKGFSQLNHPKIKLWDHFNQTYLTIEEMEKKLG
IERSQLIDYLALAGDSGNKIPGVPGIGPKSAVELLRIYRSLASIYNSIDKVGAKQAKKLEAGKQMARLSYKLVQLKTDMP
LSVNLKQFRIKKPDSE

Sequences:

>Translated_256_residues
MNKLLIIDGMNLVRRIHAAQPNESDITGLKERVHGACRKLLKYHIPTHAAIVWDGDAISWRKTLFPDYKKGRKPMPEALA
NGLNDIKAYLAEHHIHSVDADSEADDVIATLATKLVNIDGEAIIVSTDKGFSQLNHPKIKLWDHFNQTYLTIEEMEKKLG
IERSQLIDYLALAGDSGNKIPGVPGIGPKSAVELLRIYRSLASIYNSIDKVGAKQAKKLEAGKQMARLSYKLVQLKTDMP
LSVNLKQFRIKKPDSE
>Mature_256_residues
MNKLLIIDGMNLVRRIHAAQPNESDITGLKERVHGACRKLLKYHIPTHAAIVWDGDAISWRKTLFPDYKKGRKPMPEALA
NGLNDIKAYLAEHHIHSVDADSEADDVIATLATKLVNIDGEAIIVSTDKGFSQLNHPKIKLWDHFNQTYLTIEEMEKKLG
IERSQLIDYLALAGDSGNKIPGVPGIGPKSAVELLRIYRSLASIYNSIDKVGAKQAKKLEAGKQMARLSYKLVQLKTDMP
LSVNLKQFRIKKPDSE

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Escherichia coli, GI226510970, Length=252, Percent_Identity=41.2698412698413, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790294, Length=267, Percent_Identity=36.3295880149813, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XNI_SHEPA (A8H6V6)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001502828.1
- ProteinModelPortal:   A8H6V6
- SMR:   A8H6V6
- STRING:   A8H6V6
- GeneID:   5663366
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_2976
- NMPDR:   fig|398579.3.peg.2563
- eggNOG:   COG0258
- HOGENOM:   HBG701384
- OMA:   HGEKVTI
- ProtClustDB:   PRK09482
- BioCyc:   SPEA398579:SPEA_2976-MONOMER
- HAMAP:   MF_01192
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895
- SMART:   SM00475
- SMART:   SM00279

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; SSF47807 5_3_exo_C

EC number: 3.1.11.- [C]

Molecular weight: Translated: 28598; Mature: 28598

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLIIDGMNLVRRIHAAQPNESDITGLKERVHGACRKLLKYHIPTHAAIVWDGDAISW
CCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
RKTLFPDYKKGRKPMPEALANGLNDIKAYLAEHHIHSVDADSEADDVIATLATKLVNIDG
HHHCCCCHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
EAIIVSTDKGFSQLNHPKIKLWDHFNQTYLTIEEMEKKLGIERSQLIDYLALAGDSGNKI
CEEEEECCCCHHHHCCCEEEEEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
PGVPGIGPKSAVELLRIYRSLASIYNSIDKVGAKQAKKLEAGKQMARLSYKLVQLKTDMP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
LSVNLKQFRIKKPDSE
CEECHHHEEECCCCCC
>Mature Secondary Structure
MNKLLIIDGMNLVRRIHAAQPNESDITGLKERVHGACRKLLKYHIPTHAAIVWDGDAISW
CCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
RKTLFPDYKKGRKPMPEALANGLNDIKAYLAEHHIHSVDADSEADDVIATLATKLVNIDG
HHHCCCCHHCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
EAIIVSTDKGFSQLNHPKIKLWDHFNQTYLTIEEMEKKLGIERSQLIDYLALAGDSGNKI
CEEEEECCCCHHHHCCCEEEEEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
PGVPGIGPKSAVELLRIYRSLASIYNSIDKVGAKQAKKLEAGKQMARLSYKLVQLKTDMP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
LSVNLKQFRIKKPDSE
CEECHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA