Click here to switch to the map view.

The map label for this gene is mmcD [H]

Identifier: 157962620

GI number: 157962620

Start: 3418779

End: 3419657

Strand: Direct

Name: mmcD [H]

Synonym: Spea_2799

Alternate gene names: 157962620

Gene position: 3418779-3419657 (Clockwise)

Preceding gene: 157962619

Following gene: 157962621

Centisome position: 66.07

GC content: 49.26

Gene sequence:

>879_bases
ATGAATAATTCAGTCGCAACCCAGACAGAAATACTGGACCAACAATTACACTATCTGAGCTGCACGCTAAATGGCGGCGT
GGCGCAGATGGTGCTGGATCGTAGTGATAAGCACAACGCCTTCGACGAGGTGATGATAAGCGAGATGATCCAGGTACTTG
AGCACTTCAAACGCAATGAGCAGTGCCAAATATTACTGCTTAAGGCTAACGGCAAAAACTTCAGCGCGGGCGCCGATTTA
AATTGGATGCGCAAACAAGCCAAGATGGATTTTGAGCAAAACTTAGCTGACGCCAATGAGCTAGCTAGGCTTATGTCCAT
GCTCGATAAATTTCCTAAGCCGACCATAACCTTAGTACAAGGTGCAGCCTTTGGCGGTGCGCTTGGGCTTATTTGCTGCA
GTGATATCGCCATTGCCAATGAGCGCGCTAGTTTCTGCCTAAGCGAAGTCAAGCTTGGACTCATTCCTGCCGTTATTAGC
CCCTATGTGACCCGCGCCATGGGGCAGCGCGCAGCGCGCCGCTATATGCTTACCGCCGAGCGTTTCGATGCTCAAAAAGC
CCTTGAGCTACAAATTATCCATGACATCAATGATGACCTAGACGCAGCGGCTCAGCCGTTTATTGATGCGCTACTAAGCA
ATAGTCCACAGGGTATGGCTTGGGTTAAGTGCTTACTGTCATCACTTGAAGATGGCGTGATTGACCAAAACACACTGGAC
CATACCAGCGAGCGGATCGCCCGCATTCGTGTATCAGAGGAAGGTCAAGAAGGATTAAATGCCTTCTTCGAAAAGCGTAG
CCCTCAATGGCCAACGACAACAGACTTTAGCATTGCGCCTGAAAATAATAATGATGCCAGCGGGCAAGGAGCCAAATAA

Upstream 100 bases:

>100_bases
GCACCGATTGAAGACACTAAGTTTGGTGTGTTCCGTATGTAGTGGCTTAACGCCATTGCAAATAGAACATCAACTTAGCT
AACAGAGTGGATCGACAACA

Downstream 100 bases:

>100_bases
TATGTTCACTAAATTGCTAATTGCCAACCGCGGCGAAATTGCCTGCCGAATTATAGAAACCGCAAAAGCCATGGGTGTGC
GCACGGTCGCCTTATATTCC

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: MMCD; Transcarboxylase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNNSVATQTEILDQQLHYLSCTLNGGVAQMVLDRSDKHNAFDEVMISEMIQVLEHFKRNEQCQILLLKANGKNFSAGADL
NWMRKQAKMDFEQNLADANELARLMSMLDKFPKPTITLVQGAAFGGALGLICCSDIAIANERASFCLSEVKLGLIPAVIS
PYVTRAMGQRAARRYMLTAERFDAQKALELQIIHDINDDLDAAAQPFIDALLSNSPQGMAWVKCLLSSLEDGVIDQNTLD
HTSERIARIRVSEEGQEGLNAFFEKRSPQWPTTTDFSIAPENNNDASGQGAK

Sequences:

>Translated_292_residues
MNNSVATQTEILDQQLHYLSCTLNGGVAQMVLDRSDKHNAFDEVMISEMIQVLEHFKRNEQCQILLLKANGKNFSAGADL
NWMRKQAKMDFEQNLADANELARLMSMLDKFPKPTITLVQGAAFGGALGLICCSDIAIANERASFCLSEVKLGLIPAVIS
PYVTRAMGQRAARRYMLTAERFDAQKALELQIIHDINDDLDAAAQPFIDALLSNSPQGMAWVKCLLSSLEDGVIDQNTLD
HTSERIARIRVSEEGQEGLNAFFEKRSPQWPTTTDFSIAPENNNDASGQGAK
>Mature_292_residues
MNNSVATQTEILDQQLHYLSCTLNGGVAQMVLDRSDKHNAFDEVMISEMIQVLEHFKRNEQCQILLLKANGKNFSAGADL
NWMRKQAKMDFEQNLADANELARLMSMLDKFPKPTITLVQGAAFGGALGLICCSDIAIANERASFCLSEVKLGLIPAVIS
PYVTRAMGQRAARRYMLTAERFDAQKALELQIIHDINDDLDAAAQPFIDALLSNSPQGMAWVKCLLSSLEDGVIDQNTLD
HTSERIARIRVSEEGQEGLNAFFEKRSPQWPTTTDFSIAPENNNDASGQGAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=27.8884462151394, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI31542718, Length=262, Percent_Identity=24.0458015267176, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI70995211, Length=144, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=29.3893129770992, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=27.0588235294118, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787659, Length=245, Percent_Identity=27.7551020408163, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI221142681, Length=273, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=28.0155642023346, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=27.1653543307087, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=176, Percent_Identity=27.8409090909091, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=258, Percent_Identity=24.031007751938, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=256, Percent_Identity=23.046875, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=27.843137254902, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920382, Length=259, Percent_Identity=28.957528957529, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=26.7716535433071, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=26.7716535433071, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.1.41 [H]

Molecular weight: Translated: 32282; Mature: 32282

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSVATQTEILDQQLHYLSCTLNGGVAQMVLDRSDKHNAFDEVMISEMIQVLEHFKRNE
CCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QCQILLLKANGKNFSAGADLNWMRKQAKMDFEQNLADANELARLMSMLDKFPKPTITLVQ
CEEEEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEEE
GAAFGGALGLICCSDIAIANERASFCLSEVKLGLIPAVISPYVTRAMGQRAARRYMLTAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFDAQKALELQIIHDINDDLDAAAQPFIDALLSNSPQGMAWVKCLLSSLEDGVIDQNTLD
HHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH
HTSERIARIRVSEEGQEGLNAFFEKRSPQWPTTTDFSIAPENNNDASGQGAK
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNNSVATQTEILDQQLHYLSCTLNGGVAQMVLDRSDKHNAFDEVMISEMIQVLEHFKRNE
CCCCHHHHHHHHHHHHHHHEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
QCQILLLKANGKNFSAGADLNWMRKQAKMDFEQNLADANELARLMSMLDKFPKPTITLVQ
CEEEEEEEECCCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHCCCCCEEEEE
GAAFGGALGLICCSDIAIANERASFCLSEVKLGLIPAVISPYVTRAMGQRAARRYMLTAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFDAQKALELQIIHDINDDLDAAAQPFIDALLSNSPQGMAWVKCLLSSLEDGVIDQNTLD
HHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHH
HTSERIARIRVSEEGQEGLNAFFEKRSPQWPTTTDFSIAPENNNDASGQGAK
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]