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The map label for this gene is ompA [H]

Identifier: 157962526

GI number: 157962526

Start: 3303792

End: 3304766

Strand: Reverse

Name: ompA [H]

Synonym: Spea_2705

Alternate gene names: 157962526

Gene position: 3304766-3303792 (Counterclockwise)

Preceding gene: 157962527

Following gene: 157962512

Centisome position: 63.87

GC content: 46.05

Gene sequence:

>975_bases
ATGAAGCCAATGACCAAAACACTTTTCTGTTTACTCAGTCCTATGTTTGTTTACTCAAGCGCAGCTGTCGCTGAAGGCTA
TTACAGCGATGGCGATTTTTACTTTGGTGCTAAGTTAGGCGGGGCGTTACTCGATAGCCAAGCTAAGCAAGAACCTGAGG
AAAATAAGGCGGTTAACCTGAGCTCTGGCCTAGTATTCGGTTACAACTTGAACCGTTATTTAGCCCTTGAATCTGATCTT
AGCTACCTAGGCAAGGGGCAAGATAAGCAGCAAAGCACGCTATCAGCAGATAAACACTTATTCTCAATCGCGACTTATTT
ATCGACTCGATACCGGCTCAGTGACGAAGCATCGCTGTATTTTAAGCTAGGCCCAGCATGGGTGAATGATGACATATCGA
TTAGCAGTGGATTAGGCATCAAGTATCGATTTTCACCGCGCTGGGAGCTAGACACAGGCTATCGCTGGATTAAAGATACC
CCAAGTACAGATGATGACCTCTATGAGTTTACGCTTGGGTTTAACTATAAGTTTGGTGTGGTCTCGCATCCGTCTGTGCG
GCCGGCGATAGATCCTATGCATAAGCCGCTCGATAAGCAGCAAGTGCTCATAACCCCGACCATAAACGTACAATCAGTAT
CAATTCGAGGCAATAGTGTATTTGGGTTTGATAGTAGTAAGCTAACTGACACTTCAGCTCTAGATGAGGTGATAAAAAGC
GCATTAGCCAGCAAAAATGCAAGCATCAGTGTGACAGCCTATACCGATAGTTTAGGCGCCGAGCGTTATAATCTTGCTCT
CGCAAAACGCCGTGCTGAAGCGACTCAAGCCTATTTTATCACCCATGGTGTAGCACCAAGTCGCATCCATATCGACTGGA
AAGGCGAGGAAAATCCTGTGTCCAGCAACATGACGGCAAAAGGGCGCGCGTTAAATCGAAGAGTAGAAATAGAGATCGCT
GCTCACACAGACTAA

Upstream 100 bases:

>100_bases
TCCCTTTTATGCTCAATGTCGGCTATGAAAACGTGTCGGTTAATGACGTAGAAGAGCAGCGTTATAGCGATAATTTTACC
CTGATGTTTGAGGTTCTGTT

Downstream 100 bases:

>100_bases
CGTACAGATGGAACTGCGCTGTATTAGGCTAAGCTAGCTTCTGCAGAAGATAGTTTACTTTGTTAGCAGTCACTGTGTTT
GACGGTAATCACAGGTTCAG

Product: OmpA/MotB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKPMTKTLFCLLSPMFVYSSAAVAEGYYSDGDFYFGAKLGGALLDSQAKQEPEENKAVNLSSGLVFGYNLNRYLALESDL
SYLGKGQDKQQSTLSADKHLFSIATYLSTRYRLSDEASLYFKLGPAWVNDDISISSGLGIKYRFSPRWELDTGYRWIKDT
PSTDDDLYEFTLGFNYKFGVVSHPSVRPAIDPMHKPLDKQQVLITPTINVQSVSIRGNSVFGFDSSKLTDTSALDEVIKS
ALASKNASISVTAYTDSLGAERYNLALAKRRAEATQAYFITHGVAPSRIHIDWKGEENPVSSNMTAKGRALNRRVEIEIA
AHTD

Sequences:

>Translated_324_residues
MKPMTKTLFCLLSPMFVYSSAAVAEGYYSDGDFYFGAKLGGALLDSQAKQEPEENKAVNLSSGLVFGYNLNRYLALESDL
SYLGKGQDKQQSTLSADKHLFSIATYLSTRYRLSDEASLYFKLGPAWVNDDISISSGLGIKYRFSPRWELDTGYRWIKDT
PSTDDDLYEFTLGFNYKFGVVSHPSVRPAIDPMHKPLDKQQVLITPTINVQSVSIRGNSVFGFDSSKLTDTSALDEVIKS
ALASKNASISVTAYTDSLGAERYNLALAKRRAEATQAYFITHGVAPSRIHIDWKGEENPVSSNMTAKGRALNRRVEIEIA
AHTD
>Mature_324_residues
MKPMTKTLFCLLSPMFVYSSAAVAEGYYSDGDFYFGAKLGGALLDSQAKQEPEENKAVNLSSGLVFGYNLNRYLALESDL
SYLGKGQDKQQSTLSADKHLFSIATYLSTRYRLSDEASLYFKLGPAWVNDDISISSGLGIKYRFSPRWELDTGYRWIKDT
PSTDDDLYEFTLGFNYKFGVVSHPSVRPAIDPMHKPLDKQQVLITPTINVQSVSIRGNSVFGFDSSKLTDTSALDEVIKS
ALASKNASISVTAYTDSLGAERYNLALAKRRAEATQAYFITHGVAPSRIHIDWKGEENPVSSNMTAKGRALNRRVEIEIA
AHTD

Specific function: Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes [H

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787191, Length=353, Percent_Identity=25.7790368271955, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994946, Length=73, Percent_Identity=43.8356164383562, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1480 Molecules/Cell In: Growth Phase, Mi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR002368
- InterPro:   IPR006690
- InterPro:   IPR000498
- InterPro:   IPR006665 [H]

Pfam domain/function: PF00691 OmpA; PF01389 OmpA_membrane [H]

EC number: NA

Molecular weight: Translated: 35886; Mature: 35886

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMTKTLFCLLSPMFVYSSAAVAEGYYSDGDFYFGAKLGGALLDSQAKQEPEENKAVNL
CCCHHHHHHHHHHHHHHHCCHHHHCCEECCCCEEEECHHCCHHHCCHHHCCCCCCCEEEE
SSGLVFGYNLNRYLALESDLSYLGKGQDKQQSTLSADKHLFSIATYLSTRYRLSDEASLY
CCCEEEEECCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
FKLGPAWVNDDISISSGLGIKYRFSPRWELDTGYRWIKDTPSTDDDLYEFTLGFNYKFGV
EEECCEEECCCCEEECCCCEEEEECCCEECCCCCEEECCCCCCCCCEEEEEEECEEEECE
VSHPSVRPAIDPMHKPLDKQQVLITPTINVQSVSIRGNSVFGFDSSKLTDTSALDEVIKS
EECCCCCCCCCHHHCCCCCCEEEEEECCEEEEEEEECCEEECCCCCCCCCHHHHHHHHHH
ALASKNASISVTAYTDSLGAERYNLALAKRRAEATQAYFITHGVAPSRIHIDWKGEENPV
HHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCC
SSNMTAKGRALNRRVEIEIAAHTD
CCCCCCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MKPMTKTLFCLLSPMFVYSSAAVAEGYYSDGDFYFGAKLGGALLDSQAKQEPEENKAVNL
CCCHHHHHHHHHHHHHHHCCHHHHCCEECCCCEEEECHHCCHHHCCHHHCCCCCCCEEEE
SSGLVFGYNLNRYLALESDLSYLGKGQDKQQSTLSADKHLFSIATYLSTRYRLSDEASLY
CCCEEEEECCCEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEE
FKLGPAWVNDDISISSGLGIKYRFSPRWELDTGYRWIKDTPSTDDDLYEFTLGFNYKFGV
EEECCEEECCCCEEECCCCEEEEECCCEECCCCCEEECCCCCCCCCEEEEEEECEEEECE
VSHPSVRPAIDPMHKPLDKQQVLITPTINVQSVSIRGNSVFGFDSSKLTDTSALDEVIKS
EECCCCCCCCCHHHCCCCCCEEEEEECCEEEEEEEECCEEECCCCCCCCCHHHHHHHHHH
ALASKNASISVTAYTDSLGAERYNLALAKRRAEATQAYFITHGVAPSRIHIDWKGEENPV
HHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCC
SSNMTAKGRALNRRVEIEIAAHTD
CCCCCCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]