Click here to switch to the map view.

The map label for this gene is ppiD [H]

Identifier: 157962498

GI number: 157962498

Start: 3261119

End: 3262984

Strand: Reverse

Name: ppiD [H]

Synonym: Spea_2677

Alternate gene names: 157962498

Gene position: 3262984-3261119 (Counterclockwise)

Preceding gene: 157962499

Following gene: 157962490

Centisome position: 63.06

GC content: 44.21

Gene sequence:

>1866_bases
ATGTTAGAAAAGATTCGCGAAGGCTCACAAGGTGTTATTGCTAAAAGCATATTAATCCTAGTGATACTTTCATTTGCATT
TACCGGTGTGAGTAGTTATTTAGGTTCTTCAACTGAGGTTGCAGCTGCTACCGTAAATGGTGAAGAGATCAGCAACTCAG
CGTTAGAACAAGCCTATCAAAATGAGCGCAGTCGCTTAGAGCAACAGTTAGGTGATATGTTTGCTACTTTGTCTGCAGAT
GACAACTATATGCAGAGTGTTAAGCAAAGTGTATTAGAGCGCTTAGTAGCCGAGAAGCTACTAGATCAAAATGCTGCAGA
GCTAGGTCTACGCGTATCTGATGAACAGATTAAAGCTGCAATCATGTCTGAGCCTGCATTCCAAACTGACGGCGCCTTTG
ATAACGACCGTTATCAAGCTATCTTGCGTCAGCTTGGCTACCAAGCGAACTCTTTCCGCGACATGATGCGCATCGATATG
ACTCGCCGTCAGCTTGTTGCAACCTTAGTCGGTTCAGAATTTGTTCTACCTAGTGAGGCTAAGTATGTAGCCGATCTTCA
AGGTCAAACTCGTGACATTGACTACAAGGTTATCGATGCAACTCCGTTCCTTGCTGATATCAGTGTTACCGATGAACAGA
TCAAAGCTTATTACGATACTAACCTAGGTCAGTTTATTCGTCCTGAAGTGGTGAGCCTTAATTACATTGAGCTTGATGCA
AAAGATCTAGCTAAAGATGTCACAGTGACAGATGCTGAAGCGCAAGCTTATTACGATGAGCATAAAGCGAACTACACTCA
AGCTGAGAAGCGTTTAGCGGCACATATTCTTGTGCAGTCTGGTGATGATGACGCAGCTGCAAAAGCCAAGGCTGAAGCTA
TTTACAAGCAACTTCAAGACGGTGCTGATTTCGCTGAACTTGCGAAAACTGAATCTGAAGATACCTTTAGCGGTGAGCAA
GGTGGTCAACTAGATTGGTTCGAAGCCGGTGTAATGGAGCCAGAATTTGACACTGCATTGTTTGCGCTTAACAAAGGCGA
ATACTCAGGTGTTGTTAAAACGAACTTTGGTTATCACATCATCAAGGCGTTAGATATTCAGGCTGGTGCTCAGGCTCCGT
TTGCTGACGTAAAAGAGAAGATCCTTGCTCAGCTTAAAGACAAGCAAGCAGTAGATAAGTTCTACGAGCTACAGCAAGTT
TTGGCTGATACCAGCTATGAAGTACCTGATACGCTATCAGAAGCGGCTAGAGACTTAGGTGTTGAGGTTAAGACAACTCC
AGAGTTTACTCGTACTAACCCACCAGAATTGTTCACTAACCCAGAGCTACTAAACGAAGCATTCTCTTCGAACGTGCTAC
TTGATCGTATGAACAGTGATGTATTAGAAGTTGCGCCTAACCACGTAGTCGTTATTCGTGTTAATACACATAAAGCTGCT
GGTACTATGGAGCTAGCTGATGTTCGCAATGCAATTGCTAATCGTCTAAAGCAAGAGCAAGCGAACGAAGCTGCACGTAA
GCAAGCACAAGAAGCTATGACTGCTGTTGAAGCCTCTGGTGTAACAGCAGACTTCATCGTTAAAGATAAGCTTGCTCGTT
TTGCACAAGACGTGGATGGTGCGATTGTGAACAAGGCGTTCGCGATGGCTCAACCAAGCGACAAGCCTTCAGTTGATACT
GTTGCTTTAGCAAATGGTTACGCGGTAGTGGTATTGAAGCAAGTTAATGCCGCTGAAGGCGTTGACGCAAACCTTCTTGA
TTCACTCAAGCAGCGTTTAAGCTCACAATACAGTGAAAACGATTACCGTGCGGTGATCGCGTCACTAAAAGCTAAGGGTG
AAGTTCTTTACCCTGTTGCAGAGTAA

Upstream 100 bases:

>100_bases
AGAGAATATTATTATTTTCACCTCCTTTAAATTACAAAAAGGCGCATCCAAACAGTGATGCGCCTTTTTATTTTATTAAT
CGCAACAAGCGAGAAGTCTG

Downstream 100 bases:

>100_bases
ACGCTATTGAGTAAGAGCTGCTGAGTAATTGCTACTTAGCTAGCTTTACTGAATCACTAATAGTGAGCCTTATATGAGGC
ATAAAAAACCGGCTTAGGCC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLEKIREGSQGVIAKSILILVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAEKLLDQNAAELGLRVSDEQIKAAIMSEPAFQTDGAFDNDRYQAILRQLGYQANSFRDMMRIDM
TRRQLVATLVGSEFVLPSEAKYVADLQGQTRDIDYKVIDATPFLADISVTDEQIKAYYDTNLGQFIRPEVVSLNYIELDA
KDLAKDVTVTDAEAQAYYDEHKANYTQAEKRLAAHILVQSGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGEYSGVVKTNFGYHIIKALDIQAGAQAPFADVKEKILAQLKDKQAVDKFYELQQV
LADTSYEVPDTLSEAARDLGVEVKTTPEFTRTNPPELFTNPELLNEAFSSNVLLDRMNSDVLEVAPNHVVVIRVNTHKAA
GTMELADVRNAIANRLKQEQANEAARKQAQEAMTAVEASGVTADFIVKDKLARFAQDVDGAIVNKAFAMAQPSDKPSVDT
VALANGYAVVVLKQVNAAEGVDANLLDSLKQRLSSQYSENDYRAVIASLKAKGEVLYPVAE

Sequences:

>Translated_621_residues
MLEKIREGSQGVIAKSILILVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAEKLLDQNAAELGLRVSDEQIKAAIMSEPAFQTDGAFDNDRYQAILRQLGYQANSFRDMMRIDM
TRRQLVATLVGSEFVLPSEAKYVADLQGQTRDIDYKVIDATPFLADISVTDEQIKAYYDTNLGQFIRPEVVSLNYIELDA
KDLAKDVTVTDAEAQAYYDEHKANYTQAEKRLAAHILVQSGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGEYSGVVKTNFGYHIIKALDIQAGAQAPFADVKEKILAQLKDKQAVDKFYELQQV
LADTSYEVPDTLSEAARDLGVEVKTTPEFTRTNPPELFTNPELLNEAFSSNVLLDRMNSDVLEVAPNHVVVIRVNTHKAA
GTMELADVRNAIANRLKQEQANEAARKQAQEAMTAVEASGVTADFIVKDKLARFAQDVDGAIVNKAFAMAQPSDKPSVDT
VALANGYAVVVLKQVNAAEGVDANLLDSLKQRLSSQYSENDYRAVIASLKAKGEVLYPVAE
>Mature_621_residues
MLEKIREGSQGVIAKSILILVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAEKLLDQNAAELGLRVSDEQIKAAIMSEPAFQTDGAFDNDRYQAILRQLGYQANSFRDMMRIDM
TRRQLVATLVGSEFVLPSEAKYVADLQGQTRDIDYKVIDATPFLADISVTDEQIKAYYDTNLGQFIRPEVVSLNYIELDA
KDLAKDVTVTDAEAQAYYDEHKANYTQAEKRLAAHILVQSGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGEYSGVVKTNFGYHIIKALDIQAGAQAPFADVKEKILAQLKDKQAVDKFYELQQV
LADTSYEVPDTLSEAARDLGVEVKTTPEFTRTNPPELFTNPELLNEAFSSNVLLDRMNSDVLEVAPNHVVVIRVNTHKAA
GTMELADVRNAIANRLKQEQANEAARKQAQEAMTAVEASGVTADFIVKDKLARFAQDVDGAIVNKAFAMAQPSDKPSVDT
VALANGYAVVVLKQVNAAEGVDANLLDSLKQRLSSQYSENDYRAVIASLKAKGEVLYPVAE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=585, Percent_Identity=33.5042735042735, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI1786238, Length=322, Percent_Identity=25.776397515528, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68114; Mature: 68114

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIREGSQGVIAKSILILVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQ
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
NERSRLEQQLGDMFATLSADDNYMQSVKQSVLERLVAEKLLDQNAAELGLRVSDEQIKAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEECHHHHHHH
IMSEPAFQTDGAFDNDRYQAILRQLGYQANSFRDMMRIDMTRRQLVATLVGSEFVLPSEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KYVADLQGQTRDIDYKVIDATPFLADISVTDEQIKAYYDTNLGQFIRPEVVSLNYIELDA
HHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHCCCCCHHCCCCCEEEEEEEECH
KDLAKDVTVTDAEAQAYYDEHKANYTQAEKRLAAHILVQSGDDDAAAKAKAEAIYKQLQD
HHHHCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTESEDTFSGEQGGQLDWFEAGVMEPEFDTALFALNKGEYSGVVKTNFGYHI
CCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCEEEECCCEEE
IKALDIQAGAQAPFADVKEKILAQLKDKQAVDKFYELQQVLADTSYEVPDTLSEAARDLG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEVKTTPEFTRTNPPELFTNPELLNEAFSSNVLLDRMNSDVLEVAPNHVVVIRVNTHKAA
CEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCHHHCCCCEEEEEEEECCCCC
GTMELADVRNAIANRLKQEQANEAARKQAQEAMTAVEASGVTADFIVKDKLARFAQDVDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
AIVNKAFAMAQPSDKPSVDTVALANGYAVVVLKQVNAAEGVDANLLDSLKQRLSSQYSEN
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
DYRAVIASLKAKGEVLYPVAE
HHHHHHHHHHCCCCEEECCCC
>Mature Secondary Structure
MLEKIREGSQGVIAKSILILVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQ
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
NERSRLEQQLGDMFATLSADDNYMQSVKQSVLERLVAEKLLDQNAAELGLRVSDEQIKAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEECHHHHHHH
IMSEPAFQTDGAFDNDRYQAILRQLGYQANSFRDMMRIDMTRRQLVATLVGSEFVLPSEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KYVADLQGQTRDIDYKVIDATPFLADISVTDEQIKAYYDTNLGQFIRPEVVSLNYIELDA
HHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHCCCCCHHCCCCCEEEEEEEECH
KDLAKDVTVTDAEAQAYYDEHKANYTQAEKRLAAHILVQSGDDDAAAKAKAEAIYKQLQD
HHHHCCCEEECCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTESEDTFSGEQGGQLDWFEAGVMEPEFDTALFALNKGEYSGVVKTNFGYHI
CCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCEEEECCCEEE
IKALDIQAGAQAPFADVKEKILAQLKDKQAVDKFYELQQVLADTSYEVPDTLSEAARDLG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEVKTTPEFTRTNPPELFTNPELLNEAFSSNVLLDRMNSDVLEVAPNHVVVIRVNTHKAA
CEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCHHHCCCCEEEEEEEECCCCC
GTMELADVRNAIANRLKQEQANEAARKQAQEAMTAVEASGVTADFIVKDKLARFAQDVDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCH
AIVNKAFAMAQPSDKPSVDTVALANGYAVVVLKQVNAAEGVDANLLDSLKQRLSSQYSEN
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
DYRAVIASLKAKGEVLYPVAE
HHHHHHHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]