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The map label for this gene is bla [H]

Identifier: 157962458

GI number: 157962458

Start: 3215044

End: 3215883

Strand: Reverse

Name: bla [H]

Synonym: Spea_2637

Alternate gene names: 157962458

Gene position: 3215883-3215044 (Counterclockwise)

Preceding gene: 157962459

Following gene: 157962455

Centisome position: 62.15

GC content: 44.64

Gene sequence:

>840_bases
ATGACTATTTTAAAAAATCACTCGAGTATTTGGCTATTGTTTTATCTTCTGTTATCAGCTGTAGCTGTTATGCCTATAAT
GGCCTCAGCAGCCTATGAAGAGCAGTCTGACTGGCAGGCACACTTTGACAAGTATCATGCCAAGGGGACGATAGTCGTAC
TTGATAAACGTGATGCAACGGCTAAAGCTATGGTCCTAGATAACCAGCGAGCGCATAAACGTTATTCGCCGGCGTCGACA
TTCAAAATTCCCCATAGTCTGTTTGCCCTAGACTCGAATTTAGTAAAAGACGAGTTTCAAGTCTTTAACTGGGATGGTAT
TGAACGCAGTTACTCACCGCACAATCAAGATCAGAACCTACGCTCTGCCATGCGAAGTTCTGCTGTTTGGGTTTATGATG
AATTTGCTAAGCAGTTAGGTGAGAGTAAGGCTCAGAATTATTTATCGCTCATCGATTACGGTAATGCGGATCCGAGCTTT
GAGCATTCAAGTACTGACGGTAGCAGTTACTGGATTGACGGTAAGCTGGCGATTTCAGCCGCGGAGCAAGTTGAATTCCT
ACAAAAGCTGTATCGAAATCAATTGCCATTTGAATTGGCAGCTCAGCTCTTAGTCAAAGATATTATGATTGTTGAAGCGG
GAAGAGATTGGATTTTACGGGCAAAAACAGGCTGGCAGGGGCAACATGGCTGGTGGGTCGGTTGGGTTGAGTGGCCAACA
GGACCGGTGTTTTTTGCACTTAATATCGATACGCCAAATAGAATGCAAGATCTCTATAAGCGAGAGGCTATCGTACGAGA
AGTGCTGCAATCAATCGATGCTCTACCTGCTGGGCAGTAA

Upstream 100 bases:

>100_bases
TATCAGACCGTTAGTGGTTGTGATGTCTATTGCCATGAGCGTTAAGCTATTATCAAGCCAGTACGACCTGTTTGCTTGGT
TTTAATCGAGATCTTCAAGG

Downstream 100 bases:

>100_bases
TCCCTTTACTAACTCACTTTTTTTCAGCCCTAAACCACCTACTTAGAAGGCGGATTCTTTGCTTAGGCTAGCTCCTTAAA
ATTAAAAGCCCCTTAGTGCT

Product: beta-lactamase

Products: NA

Alternate protein names: Penicillinase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTILKNHSSIWLLFYLLLSAVAVMPIMASAAYEEQSDWQAHFDKYHAKGTIVVLDKRDATAKAMVLDNQRAHKRYSPAST
FKIPHSLFALDSNLVKDEFQVFNWDGIERSYSPHNQDQNLRSAMRSSAVWVYDEFAKQLGESKAQNYLSLIDYGNADPSF
EHSSTDGSSYWIDGKLAISAAEQVEFLQKLYRNQLPFELAAQLLVKDIMIVEAGRDWILRAKTGWQGQHGWWVGWVEWPT
GPVFFALNIDTPNRMQDLYKREAIVREVLQSIDALPAGQ

Sequences:

>Translated_279_residues
MTILKNHSSIWLLFYLLLSAVAVMPIMASAAYEEQSDWQAHFDKYHAKGTIVVLDKRDATAKAMVLDNQRAHKRYSPAST
FKIPHSLFALDSNLVKDEFQVFNWDGIERSYSPHNQDQNLRSAMRSSAVWVYDEFAKQLGESKAQNYLSLIDYGNADPSF
EHSSTDGSSYWIDGKLAISAAEQVEFLQKLYRNQLPFELAAQLLVKDIMIVEAGRDWILRAKTGWQGQHGWWVGWVEWPT
GPVFFALNIDTPNRMQDLYKREAIVREVLQSIDALPAGQ
>Mature_278_residues
TILKNHSSIWLLFYLLLSAVAVMPIMASAAYEEQSDWQAHFDKYHAKGTIVVLDKRDATAKAMVLDNQRAHKRYSPASTF
KIPHSLFALDSNLVKDEFQVFNWDGIERSYSPHNQDQNLRSAMRSSAVWVYDEFAKQLGESKAQNYLSLIDYGNADPSFE
HSSTDGSSYWIDGKLAISAAEQVEFLQKLYRNQLPFELAAQLLVKDIMIVEAGRDWILRAKTGWQGQHGWWVGWVEWPTG
PVFFALNIDTPNRMQDLYKREAIVREVLQSIDALPAGQ

Specific function: This is an oxacillin-hydrolyzing beta-lactamase [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 31891; Mature: 31760

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILKNHSSIWLLFYLLLSAVAVMPIMASAAYEEQSDWQAHFDKYHAKGTIVVLDKRDAT
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCC
AKAMVLDNQRAHKRYSPASTFKIPHSLFALDSNLVKDEFQVFNWDGIERSYSPHNQDQNL
EEEEEECCHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHH
RSAMRSSAVWVYDEFAKQLGESKAQNYLSLIDYGNADPSFEHSSTDGSSYWIDGKLAISA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEEEHH
AEQVEFLQKLYRNQLPFELAAQLLVKDIMIVEAGRDWILRAKTGWQGQHGWWVGWVEWPT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCEEEEEEECCC
GPVFFALNIDTPNRMQDLYKREAIVREVLQSIDALPAGQ
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TILKNHSSIWLLFYLLLSAVAVMPIMASAAYEEQSDWQAHFDKYHAKGTIVVLDKRDAT
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCC
AKAMVLDNQRAHKRYSPASTFKIPHSLFALDSNLVKDEFQVFNWDGIERSYSPHNQDQNL
EEEEEECCHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHH
RSAMRSSAVWVYDEFAKQLGESKAQNYLSLIDYGNADPSFEHSSTDGSSYWIDGKLAISA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEEEHH
AEQVEFLQKLYRNQLPFELAAQLLVKDIMIVEAGRDWILRAKTGWQGQHGWWVGWVEWPT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCEEEEEEECCC
GPVFFALNIDTPNRMQDLYKREAIVREVLQSIDALPAGQ
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9687410 [H]