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The map label for this gene is avtA [H]

Identifier: 157962456

GI number: 157962456

Start: 3208916

End: 3210166

Strand: Direct

Name: avtA [H]

Synonym: Spea_2635

Alternate gene names: 157962456

Gene position: 3208916-3210166 (Clockwise)

Preceding gene: 157962451

Following gene: 157962457

Centisome position: 62.01

GC content: 47.0

Gene sequence:

>1251_bases
ATGCAGTTTTCAAAGTTTGGTGAAAAATTTAATCGTTATTCCGGCATTACCCAGTTAATGGATGATCTCAATGAAGGATT
GCGCACTCCAGGCGCAATTATGCTTGGCGGAGGCAACCCCGCTTCTATTCCAGCCATGCAAGATTACTTTCATCAGGCGA
CGGCAGATATGCTAGCCAATGGCGAACTCGTCGCGGCATTAAGCAATTATGACGGCCCTCAAGGAAAAGACGCCTTCTTA
ACGGCTCTAGCGACTTTACTACGTGATACTTATGGCTGGGAGATCAGCGAGAAAAACATCAGCCTAAGTAATGGCAGCCA
GAGTGCGTTTTTCAACTTGTTTAATCTACTCGCGGGTGAACAAAGCGATGGCTGCATAAAGAAAATCTTACTGCCCCTTG
CCCCCGAATACATTGGCTACAACGATGCGGGTCTAGATGATGACATTTTTGTCTCTTACCGCCCCGATATTGAGATGCTA
GATAATCGCATGTTTAAGTACCATGTAGATTTCGAGCAGTTGCAAATCGATGACTCGATTGCCGCAATCTGTGTGTCTCG
ACCAACGAACCCCACTGGTAACGTGCTCACCGATGCAGAAATCAGTAAACTCGACGAGTTAGCACGTGCAAAGGGCGTCC
CTCTCATCATAGACAATGCCTACGGCACGCCATTTCCCAATATCATTTTTGAGGAAGTGACACCATTTTGGAACAGCAAC
ACCATCTTGTGTATGAGCCTATCTAAACTTGGCCTACCCGGTGTGCGCTGCGGCATAGTGATCGCGAGCGAAGAGATCAC
GGCAGCACTTTCTAACCTCAATGCTATCATCAGCCTAGCACCAGGGGGATTTGGCCCCGCCATAGCTAAACACATGATTG
AGTCGGGCGACCTGCTGCATTTAAGCGAAAATGTTATCAAGCCTTTTTATCAGCAAAAGTCTGAGTTTGCCGTGTCATTA
CTGCAGCAATCTATTAGCGATAGCCGATTCAGAATTCACAAACCCGAAGGCGCGATGTTCCTCTGGCTTTGGTTTGATAA
ATTACCTATCACCACCATGGAGCTTTATAACAGGCTGAAAGCCCGTGGCGTATTAATTGTACCGGGCGAGTATTTTTTCT
TTGGATTAGAGCAAGATTGGGAGCATGCGCATCAGTGCTTACGCATGAACTATGTGCAAGATGAAGCCAAAATGCGTGCT
GGCATCGCGATTATCAGCGAAGAAGTCGCCAAGGCCTACACAGAACTTTAA

Upstream 100 bases:

>100_bases
ATGAATGCCAAATTAATCACTAAAAAATCAAAAAGGGGGTGCGTTTTTCACTGAGTATTGTTACTACAGGCGTACTTAAG
TAATTGTGGTACTAGATAGC

Downstream 100 bases:

>100_bases
AACCATAGAGCTTTAAAACCATACAGCTAACTTTGTAAACTTCCTCCCCATTAAATACCGATAAGCGATTGCTCAGGTTT
CTAGTCAGAACTAGATCTGA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQFSKFGEKFNRYSGITQLMDDLNEGLRTPGAIMLGGGNPASIPAMQDYFHQATADMLANGELVAALSNYDGPQGKDAFL
TALATLLRDTYGWEISEKNISLSNGSQSAFFNLFNLLAGEQSDGCIKKILLPLAPEYIGYNDAGLDDDIFVSYRPDIEML
DNRMFKYHVDFEQLQIDDSIAAICVSRPTNPTGNVLTDAEISKLDELARAKGVPLIIDNAYGTPFPNIIFEEVTPFWNSN
TILCMSLSKLGLPGVRCGIVIASEEITAALSNLNAIISLAPGGFGPAIAKHMIESGDLLHLSENVIKPFYQQKSEFAVSL
LQQSISDSRFRIHKPEGAMFLWLWFDKLPITTMELYNRLKARGVLIVPGEYFFFGLEQDWEHAHQCLRMNYVQDEAKMRA
GIAIISEEVAKAYTEL

Sequences:

>Translated_416_residues
MQFSKFGEKFNRYSGITQLMDDLNEGLRTPGAIMLGGGNPASIPAMQDYFHQATADMLANGELVAALSNYDGPQGKDAFL
TALATLLRDTYGWEISEKNISLSNGSQSAFFNLFNLLAGEQSDGCIKKILLPLAPEYIGYNDAGLDDDIFVSYRPDIEML
DNRMFKYHVDFEQLQIDDSIAAICVSRPTNPTGNVLTDAEISKLDELARAKGVPLIIDNAYGTPFPNIIFEEVTPFWNSN
TILCMSLSKLGLPGVRCGIVIASEEITAALSNLNAIISLAPGGFGPAIAKHMIESGDLLHLSENVIKPFYQQKSEFAVSL
LQQSISDSRFRIHKPEGAMFLWLWFDKLPITTMELYNRLKARGVLIVPGEYFFFGLEQDWEHAHQCLRMNYVQDEAKMRA
GIAIISEEVAKAYTEL
>Mature_416_residues
MQFSKFGEKFNRYSGITQLMDDLNEGLRTPGAIMLGGGNPASIPAMQDYFHQATADMLANGELVAALSNYDGPQGKDAFL
TALATLLRDTYGWEISEKNISLSNGSQSAFFNLFNLLAGEQSDGCIKKILLPLAPEYIGYNDAGLDDDIFVSYRPDIEML
DNRMFKYHVDFEQLQIDDSIAAICVSRPTNPTGNVLTDAEISKLDELARAKGVPLIIDNAYGTPFPNIIFEEVTPFWNSN
TILCMSLSKLGLPGVRCGIVIASEEITAALSNLNAIISLAPGGFGPAIAKHMIESGDLLHLSENVIKPFYQQKSEFAVSL
LQQSISDSRFRIHKPEGAMFLWLWFDKLPITTMELYNRLKARGVLIVPGEYFFFGLEQDWEHAHQCLRMNYVQDEAKMRA
GIAIISEEVAKAYTEL

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=415, Percent_Identity=62.8915662650602, Blast_Score=566, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46154; Mature: 46154

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSKFGEKFNRYSGITQLMDDLNEGLRTPGAIMLGGGNPASIPAMQDYFHQATADMLAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
GELVAALSNYDGPQGKDAFLTALATLLRDTYGWEISEKNISLSNGSQSAFFNLFNLLAGE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEECCEEEECCCCHHHHHHHHHHHCCC
QSDGCIKKILLPLAPEYIGYNDAGLDDDIFVSYRPDIEMLDNRMFKYHVDFEQLQIDDSI
CCCHHHHHHHHHHCHHHCCCCCCCCCCCEEEEECCCHHHHCCCEEEEECCHHHEEECCCC
AAICVSRPTNPTGNVLTDAEISKLDELARAKGVPLIIDNAYGTPFPNIIFEEVTPFWNSN
EEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCCCC
TILCMSLSKLGLPGVRCGIVIASEEITAALSNLNAIISLAPGGFGPAIAKHMIESGDLLH
EEEEEEHHHCCCCCCEEEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEE
LSENVIKPFYQQKSEFAVSLLQQSISDSRFRIHKPEGAMFLWLWFDKLPITTMELYNRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFFGLEQDWEHAHQCLRMNYVQDEAKMRAGIAIISEEVAKAYTEL
HCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFSKFGEKFNRYSGITQLMDDLNEGLRTPGAIMLGGGNPASIPAMQDYFHQATADMLAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
GELVAALSNYDGPQGKDAFLTALATLLRDTYGWEISEKNISLSNGSQSAFFNLFNLLAGE
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEECCEEEECCCCHHHHHHHHHHHCCC
QSDGCIKKILLPLAPEYIGYNDAGLDDDIFVSYRPDIEMLDNRMFKYHVDFEQLQIDDSI
CCCHHHHHHHHHHCHHHCCCCCCCCCCCEEEEECCCHHHHCCCEEEEECCHHHEEECCCC
AAICVSRPTNPTGNVLTDAEISKLDELARAKGVPLIIDNAYGTPFPNIIFEEVTPFWNSN
EEEEEECCCCCCCCEECCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCCCCCC
TILCMSLSKLGLPGVRCGIVIASEEITAALSNLNAIISLAPGGFGPAIAKHMIESGDLLH
EEEEEEHHHCCCCCCEEEEEEECHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCEEE
LSENVIKPFYQQKSEFAVSLLQQSISDSRFRIHKPEGAMFLWLWFDKLPITTMELYNRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFFGLEQDWEHAHQCLRMNYVQDEAKMRAGIAIISEEVAKAYTEL
HCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]