| Definition | Shewanella pealeana ATCC 700345 chromosome, complete genome. |
|---|---|
| Accession | NC_009901 |
| Length | 5,174,581 |
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The map label for this gene is clpA [H]
Identifier: 157962353
GI number: 157962353
Start: 3082342
End: 3084600
Strand: Reverse
Name: clpA [H]
Synonym: Spea_2532
Alternate gene names: 157962353
Gene position: 3084600-3082342 (Counterclockwise)
Preceding gene: 157962354
Following gene: 157962349
Centisome position: 59.61
GC content: 47.72
Gene sequence:
>2259_bases ATGTTAAATAAAGATCTTGAAGTCACCTTAAATCTGGCTTTTCAACAAGCCAGAGATGCCCGTCATGAGTACATGACTGT TGAGCATCTATTGTTGGCATTAATCGATAACCCAGCCGCACAAGAGGCGTTAGTTGCTTGCGGAGCAAATTTAGAGAAAT TAAGAGATGAAGTCTCTAGTTTCATTCAACAGACCACGCCAATTATCTCCGATCCCGAAGACGAGAAAGAGACTCAACCG ACACTGGGCTTTCAACGCGTTCTGCAAAGAGCCGTATTTCACGTGCAGTCATCAGGCCGCAATGAGGTCAACGGTGCTAA CGTCTTAGTCGCTATTTTCAGTGAACAAGAGTCTCAAGCGGTTTACCTGCTTCGAACTGGCGATGTGACCCGTTTAGATG TGGTCAATTTTATTTCCCATGGCTTTTCGAAAAACGATATCGATACCGGCCCAGAGCAAAGCCGTATCGAAGATCAAACC GAGAACGAAGAAGAGCGCAGTATCTTGTCTCAGTTTACCGCTAACCTGAATGAGTTAGCTAAAAACGGCAGTATTGACCC GCTGATTGGCCGTACCGATGAGATTGAGCGCTCGATTCAAATTCTTTGCCGTCGCCGTAAGAATAACCCACTGCTCGTGG GTGAGGCTGGGGTGGGTAAAACCGCCATTGCTGAAGGCTTAGCTTATCGCATCGTTAAAGAAGAAGTGCCTGAGGTGATG AGTGAAGCGACCGTATACTCCCTCGACTTAGGTGCATTGCTTGCCGGTACCAAGTACCGTGGTGATTTTGAGAAGCGTTT TAAAGGCTTACTCAAAGAGTTAGCGAATGACGAGCATGCGATCTTATTTATCGATGAGATCCATACCATTATTGGTGCAG GCTCGGCTTCAGGTGGTGTCATGGATGCCTCTAACTTGCTTAAACCGCTGTTATCGGGTGGTAAACTACGCTGTATGGGC TCGACCACGTTTCAAGAGTACCAAAGTATTTTTGAGAAGGACCGAGCGCTAGCCCGTCGCTTCCAGAAGGTGGACATTAA CGAACCATCGGTTGCTGAGACTACAAAGATTTTACAAGGTCTTAAGTCAAAGTACGAAGAGCACCACAATGTGCGCTATA CCATGGCAGCATTGAGCGTGGCAGCAAGGTTATCAGATAAGCATATCAACGATAGACATCTGCCAGATAAAGCCATCGAT GTGATTGACGAAGCGGGTGCACGCATGGCGATGCAGCCAGCGAGCAAACGTAAAAAGACGATTGGTCAAGCGGAGATCGA GTCGATTATCGCTAAGATGGCGCGTATTCCTGAGAAGTCCGTATCGAGCTCTGACAAGGATATGCTTAAAAACCTTGAGC GTAACCTTAAGATGGTGGTGTTTGGCCAAGATCAGGCGATTGAGGGGCTTAGTTCGGCAATTCGCTTGTCTCGAAGTGGT CTAGGTGGTGAGCACAAGCCTGTAGGTAGCTTCCTGTTTGCTGGTCCTACCGGTGTCGGTAAAACAGAGGTCACCAGTCA GCTTGCTAAATGTTTAAGTCTGAAGCTGGTTCGATTCGATATGTCGGAATACATGGAAAGCCATACCGTGTCACGTCTGA TTGGCGCGCCTCCTGGTTATGTCGGCTATGACCAAGGTGGGCTATTAACCGACGCTGTGATTAAGAATCCACATTGTGTG GTGCTGCTCGATGAGATTGAGAAGGCGCATCCTGATGTGTATAACTTGCTACTGCAGGTGATGGATCACGGTACTTTGAC CGATAATAATGGCCGTAAAGCTGACTTTAGGCATGTCACCCTCGTGATGACGACTAACGCCGGTGTACAGGAAACCATTC GAAAGTCGATAGGCTTTAAGCAGCAAGACCATACTCAGGATGCCTTGTCGGAAATCAATAAGGTGTTTTCGCCTGAGTTC CGTAACCGACTCGACTCGATTATCTGGTTCAACCATCTGGATATGACGGTAATCGCGAAAGTGGTTGATAAGTTCTTAGT TGAACTACAAGCACAGCTTGATGATAAGTCTGTGACGCTCGATGTCAGCGACGAAGCGAGAACCTTACTTGCAGAGAAAG GTTACGATAAGTCGATGGGGGCACGTCCGATGGCTCGTGTGGTTACCGAGCTTATCAAGCGACCTCTAGCCGATGAGATC TTATTCGGCGAGTTAGAGAAGGGCGGTATCGCCCGAGTCGACGCTAAAGGCGATGAGATTGTGATCACCACAGAATCGCT AGAAAAAGTCACTCATTAA
Upstream 100 bases:
>100_bases AAGTAAATCAATTTGCAAGACAAAACCAACATCCGTTACTGTGTTCATTAGAGGAAGCCTAAATTTGGCCGAATCTGTAG TATTTTTTTAGGGGGTGCTT
Downstream 100 bases:
>100_bases CTTGAGTGTATGGATCAGCAAGCATGTGTTTGTTGGTCCATACCTGCTAAATAATCATTTGGTCGATAGAATTACAGACA ACAAAAAGCCGGCATAGCCG
Product: ATP-dependent Clp protease, ATP-binding subunit clpA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 752; Mature: 752
Protein sequence:
>752_residues MLNKDLEVTLNLAFQQARDARHEYMTVEHLLLALIDNPAAQEALVACGANLEKLRDEVSSFIQQTTPIISDPEDEKETQP TLGFQRVLQRAVFHVQSSGRNEVNGANVLVAIFSEQESQAVYLLRTGDVTRLDVVNFISHGFSKNDIDTGPEQSRIEDQT ENEEERSILSQFTANLNELAKNGSIDPLIGRTDEIERSIQILCRRRKNNPLLVGEAGVGKTAIAEGLAYRIVKEEVPEVM SEATVYSLDLGALLAGTKYRGDFEKRFKGLLKELANDEHAILFIDEIHTIIGAGSASGGVMDASNLLKPLLSGGKLRCMG STTFQEYQSIFEKDRALARRFQKVDINEPSVAETTKILQGLKSKYEEHHNVRYTMAALSVAARLSDKHINDRHLPDKAID VIDEAGARMAMQPASKRKKTIGQAEIESIIAKMARIPEKSVSSSDKDMLKNLERNLKMVVFGQDQAIEGLSSAIRLSRSG LGGEHKPVGSFLFAGPTGVGKTEVTSQLAKCLSLKLVRFDMSEYMESHTVSRLIGAPPGYVGYDQGGLLTDAVIKNPHCV VLLDEIEKAHPDVYNLLLQVMDHGTLTDNNGRKADFRHVTLVMTTNAGVQETIRKSIGFKQQDHTQDALSEINKVFSPEF RNRLDSIIWFNHLDMTVIAKVVDKFLVELQAQLDDKSVTLDVSDEARTLLAEKGYDKSMGARPMARVVTELIKRPLADEI LFGELEKGGIARVDAKGDEIVITTESLEKVTH
Sequences:
>Translated_752_residues MLNKDLEVTLNLAFQQARDARHEYMTVEHLLLALIDNPAAQEALVACGANLEKLRDEVSSFIQQTTPIISDPEDEKETQP TLGFQRVLQRAVFHVQSSGRNEVNGANVLVAIFSEQESQAVYLLRTGDVTRLDVVNFISHGFSKNDIDTGPEQSRIEDQT ENEEERSILSQFTANLNELAKNGSIDPLIGRTDEIERSIQILCRRRKNNPLLVGEAGVGKTAIAEGLAYRIVKEEVPEVM SEATVYSLDLGALLAGTKYRGDFEKRFKGLLKELANDEHAILFIDEIHTIIGAGSASGGVMDASNLLKPLLSGGKLRCMG STTFQEYQSIFEKDRALARRFQKVDINEPSVAETTKILQGLKSKYEEHHNVRYTMAALSVAARLSDKHINDRHLPDKAID VIDEAGARMAMQPASKRKKTIGQAEIESIIAKMARIPEKSVSSSDKDMLKNLERNLKMVVFGQDQAIEGLSSAIRLSRSG LGGEHKPVGSFLFAGPTGVGKTEVTSQLAKCLSLKLVRFDMSEYMESHTVSRLIGAPPGYVGYDQGGLLTDAVIKNPHCV VLLDEIEKAHPDVYNLLLQVMDHGTLTDNNGRKADFRHVTLVMTTNAGVQETIRKSIGFKQQDHTQDALSEINKVFSPEF RNRLDSIIWFNHLDMTVIAKVVDKFLVELQAQLDDKSVTLDVSDEARTLLAEKGYDKSMGARPMARVVTELIKRPLADEI LFGELEKGGIARVDAKGDEIVITTESLEKVTH >Mature_752_residues MLNKDLEVTLNLAFQQARDARHEYMTVEHLLLALIDNPAAQEALVACGANLEKLRDEVSSFIQQTTPIISDPEDEKETQP TLGFQRVLQRAVFHVQSSGRNEVNGANVLVAIFSEQESQAVYLLRTGDVTRLDVVNFISHGFSKNDIDTGPEQSRIEDQT ENEEERSILSQFTANLNELAKNGSIDPLIGRTDEIERSIQILCRRRKNNPLLVGEAGVGKTAIAEGLAYRIVKEEVPEVM SEATVYSLDLGALLAGTKYRGDFEKRFKGLLKELANDEHAILFIDEIHTIIGAGSASGGVMDASNLLKPLLSGGKLRCMG STTFQEYQSIFEKDRALARRFQKVDINEPSVAETTKILQGLKSKYEEHHNVRYTMAALSVAARLSDKHINDRHLPDKAID VIDEAGARMAMQPASKRKKTIGQAEIESIIAKMARIPEKSVSSSDKDMLKNLERNLKMVVFGQDQAIEGLSSAIRLSRSG LGGEHKPVGSFLFAGPTGVGKTEVTSQLAKCLSLKLVRFDMSEYMESHTVSRLIGAPPGYVGYDQGGLLTDAVIKNPHCV VLLDEIEKAHPDVYNLLLQVMDHGTLTDNNGRKADFRHVTLVMTTNAGVQETIRKSIGFKQQDHTQDALSEINKVFSPEF RNRLDSIIWFNHLDMTVIAKVVDKFLVELQAQLDDKSVTLDVSDEARTLLAEKGYDKSMGARPMARVVTELIKRPLADEI LFGELEKGGIARVDAKGDEIVITTESLEKVTH
Specific function: ATP-dependent specificity component of the ClpP protease. It directs the protease to specific substrates. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins [H]
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=32.5503355704698, Blast_Score=150, Evalue=6e-36, Organism=Escherichia coli, GI1787109, Length=755, Percent_Identity=69.0066225165563, Blast_Score=1085, Evalue=0.0, Organism=Escherichia coli, GI1788943, Length=416, Percent_Identity=43.2692307692308, Blast_Score=296, Evalue=4e-81, Organism=Saccharomyces cerevisiae, GI6320464, Length=330, Percent_Identity=43.9393939393939, Blast_Score=278, Evalue=2e-75, Organism=Saccharomyces cerevisiae, GI6323002, Length=413, Percent_Identity=38.2566585956416, Blast_Score=260, Evalue=7e-70,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR013461 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 83230; Mature: 83230
Theoretical pI: Translated: 5.58; Mature: 5.58
Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNKDLEVTLNLAFQQARDARHEYMTVEHLLLALIDNPAAQEALVACGANLEKLRDEVSS CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH FIQQTTPIISDPEDEKETQPTLGFQRVLQRAVFHVQSSGRNEVNGANVLVAIFSEQESQA HHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCE VYLLRTGDVTRLDVVNFISHGFSKNDIDTGPEQSRIEDQTENEEERSILSQFTANLNELA EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH KNGSIDPLIGRTDEIERSIQILCRRRKNNPLLVGEAGVGKTAIAEGLAYRIVKEEVPEVM HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH SEATVYSLDLGALLAGTKYRGDFEKRFKGLLKELANDEHAILFIDEIHTIIGAGSASGGV HHHHEEEECHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCC MDASNLLKPLLSGGKLRCMGSTTFQEYQSIFEKDRALARRFQKVDINEPSVAETTKILQG CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH LKSKYEEHHNVRYTMAALSVAARLSDKHINDRHLPDKAIDVIDEAGARMAMQPASKRKKT HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHCCCHHHHHHH IGQAEIESIIAKMARIPEKSVSSSDKDMLKNLERNLKMVVFGQDQAIEGLSSAIRLSRSG CCHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCC LGGEHKPVGSFLFAGPTGVGKTEVTSQLAKCLSLKLVRFDMSEYMESHTVSRLIGAPPGY CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC VGYDQGGLLTDAVIKNPHCVVLLDEIEKAHPDVYNLLLQVMDHGTLTDNNGRKADFRHVT CCCCCCCCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCCCEEEE LVMTTNAGVQETIRKSIGFKQQDHTQDALSEINKVFSPEFRNRLDSIIWFNHLDMTVIAK EEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH VVDKFLVELQAQLDDKSVTLDVSDEARTLLAEKGYDKSMGARPMARVVTELIKRPLADEI HHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHH LFGELEKGGIARVDAKGDEIVITTESLEKVTH HHHCCCCCCEEEEECCCCEEEEEHHHHHHHCC >Mature Secondary Structure MLNKDLEVTLNLAFQQARDARHEYMTVEHLLLALIDNPAAQEALVACGANLEKLRDEVSS CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHH FIQQTTPIISDPEDEKETQPTLGFQRVLQRAVFHVQSSGRNEVNGANVLVAIFSEQESQA HHHHCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCE VYLLRTGDVTRLDVVNFISHGFSKNDIDTGPEQSRIEDQTENEEERSILSQFTANLNELA EEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH KNGSIDPLIGRTDEIERSIQILCRRRKNNPLLVGEAGVGKTAIAEGLAYRIVKEEVPEVM HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH SEATVYSLDLGALLAGTKYRGDFEKRFKGLLKELANDEHAILFIDEIHTIIGAGSASGGV HHHHEEEECHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCC MDASNLLKPLLSGGKLRCMGSTTFQEYQSIFEKDRALARRFQKVDINEPSVAETTKILQG CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH LKSKYEEHHNVRYTMAALSVAARLSDKHINDRHLPDKAIDVIDEAGARMAMQPASKRKKT HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHCCCHHHHHHH IGQAEIESIIAKMARIPEKSVSSSDKDMLKNLERNLKMVVFGQDQAIEGLSSAIRLSRSG CCHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCC LGGEHKPVGSFLFAGPTGVGKTEVTSQLAKCLSLKLVRFDMSEYMESHTVSRLIGAPPGY CCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC VGYDQGGLLTDAVIKNPHCVVLLDEIEKAHPDVYNLLLQVMDHGTLTDNNGRKADFRHVT CCCCCCCCCHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCCCEEEE LVMTTNAGVQETIRKSIGFKQQDHTQDALSEINKVFSPEFRNRLDSIIWFNHLDMTVIAK EEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH VVDKFLVELQAQLDDKSVTLDVSDEARTLLAEKGYDKSMGARPMARVVTELIKRPLADEI HHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHH LFGELEKGGIARVDAKGDEIVITTESLEKVTH HHHCCCCCCEEEEECCCCEEEEEHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]