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The map label for this gene is chvG [H]

Identifier: 157962340

GI number: 157962340

Start: 3069089

End: 3071275

Strand: Direct

Name: chvG [H]

Synonym: Spea_2519

Alternate gene names: 157962340

Gene position: 3069089-3071275 (Clockwise)

Preceding gene: 157962339

Following gene: 157962341

Centisome position: 59.31

GC content: 47.83

Gene sequence:

>2187_bases
ATGTTCAATTTGCCCATAGGTCTTCGCGCTAAAGTCGCGGTTTTATCATTGTTTTTGCTCTGCCTTCCTTGGCTGGGATA
TCAGTACGTGTGGGAGATGGAAAAATACCTGCGTCACGGCCAAGAAAAAACCTTGGAGGGCACAACACAAGCGTTAGCAA
CCGCCCTGCACGAGAGACCAAAACTATTCGACAGCCAAGCCAGCTTCTTAACTCAGGTCGAGAAAGGCCGCGATCTTTAT
GCATATCCGCTTTCGGGCCCCATTCAACTCGATGGCAAGCTGGCAGACTGGAGCAGCTATCGCCACCGCGCTCTAAACTA
CGGCAGCGACTATCAGATCTATAAACGCGATGAGAGCCAGCCACTGCAGCTCAGCTTTACTCATATGGTGGGCAAATACG
CCGGTTACTTATATGCGTTTTTCGAGGTTAACGATCCCCAAGTGGTCTACCGTGGTAAAAATAGCCTTAGCATAGATAGA
AACGATCATATCGCTATTGCCACACTCGCCCCCGATGGCATGTTCCGACGTTATATTATTGCAACGACCCAAGATGGCTG
GATCAGTGCCTTTGAACTCCCTGAAGATCCAAGCCTAAGCAAACCTGTGACCCCCGAAGTCAAGATCCAAGGTAAATGGA
CCAAGAGTAAACAGGGCTACAATGTCGAGCTGCGGATCCCGCTCGACATGGTGGGCAGTAAACTTGGTTTTGTGGTTTAT
GACGTCAATGACAAGCATAGCCGCGCCCTCGATGCTGCCGTAGGCACATCCGCTATTGATGATGTCAGCAAGCTAGGAAC
GGTACTGGTGCCTTCACCTGAGATAGAGAGCATCATTAAAGGCATGAGCCATAATAGCTCACGTATTTGGGTGGTGGATA
AACATGGTCGCGTACTGGCAAAGTCTGGCGATATTCGCTCTGACAACAGCGTGTGGTCACGATCTGCCATAGAAAAAGAG
GGTAACTCCACCTGGGAGAAGTTTAAGCGTGACTACCTGCACCCGCTTTATTACAAAATTCTTACCACTCCGGCGAAAGA
CTTTATCGACTCTTTGCAAGACTCAACCGTACTGCAAGGCAGTCATATCTCTAAGGCGCTCAATGGCGAGCAAGGCTCAA
CCTGGCGATTAACTCCCGACAACAAAGCCGTGGTGCTCGCTGCTGCAAGCCCTATCTGGATCGATGACAAGGTGATGGGC
GTCGTGATCGCCGAAGAGACCACTCATGGCATTCGCACTTTGAGAAATAAGGCCTTAGAAAAACTATTCAATGTGATTTT
AACCATCATGAGTATGGGCACCTTGGCATTATTTTTCTTCGCCTCAAACATCTCTAGCCGAATTCGAAAACTGCGCGATG
AAGCCGAACAAGCCATCGATAGTCAAGGCCGGATTAAAAATGAAATTCAAGGCTCTAAGGTGCGTGATGAAATTGGCGAT
CTGTCGCGCAGTTTCGCCAGTATTGTCAGCCGCTTGAGTCAATATACTCATTACTTAGAGAATATGTCATCGCGCTTATC
TCACGAGCTGCGAACTCCTGTTGCCGTAGTACGTTCATCGTTAGAACACCTTGGCCTACAAGAGCTAAACCCCGATACTC
GCAAATATGTTGACCGGGCACAGGAAGGGGTTAACCGCCTTAACATGATCCTCAATAATATGAGCGAAGCAACCCGCTTA
GAAGAGAGCCTTTCCCATGCTGAGAAAACCGTTTTTCCATTAGAAAAAGTTGTCAGCGGTTGCATGCAGGGTTACCAGAT
GACCTATCCAGATCAAACCTTCAGCCTTGAGATCATTAACGAAGAAACTCCCATTCTTGGAGTGCCTGAATATATCGCCC
AACTAATGGATAAACTTGTTGCCAATGCATTAGAGTTTAGCCATCCGCACACCCCGATTGACGTTTCACTCAAGCTTAAG
AATAAGTTTGCCGAGCTTAGGATCAGTAACCAGGGTCCTGCTCTGCCTGAAAATATGGCTGAGCAAATTTTCGAGTCTAT
GGTCTCAGTGCGTATGCAAAAGGCACAAGACAAACCTCATCTGGGACTCGGTCTGTATATCGCACGGCTTATCAGTCAGT
TCCACCAAGGTCAGATCAATGCCCGTAACTTACAAGATAAGTCGGGTGAGATCAGCGGTGTTGAGATAAAAATCAGACTA
CCTTTGAGTAAAGAAACTCTGCCATAA

Upstream 100 bases:

>100_bases
TTAGTTCCCTGTTACTTAATTTGTCCATTTGATTTACGCAATTTTAATTACAGAGTTTTAGTCACTTCAATTAAGTTATT
AGTTAGGTAAGCATTCATCC

Downstream 100 bases:

>100_bases
ACCCAGCCTAATAAAATTCTAACAGTTTGATATTTAGTGCTAAATCAGCTCGTATAATAAGGATGGAAACGCCGATTACA
AACAATTGAGATAGCAAATT

Product: histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MFNLPIGLRAKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGSDYQIYKRDESQPLQLSFTHMVGKYAGYLYAFFEVNDPQVVYRGKNSLSIDR
NDHIAIATLAPDGMFRRYIIATTQDGWISAFELPEDPSLSKPVTPEVKIQGKWTKSKQGYNVELRIPLDMVGSKLGFVVY
DVNDKHSRALDAAVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRSAIEKE
GNSTWEKFKRDYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQELNPDTRKYVDRAQEGVNRLNMILNNMSEATRL
EESLSHAEKTVFPLEKVVSGCMQGYQMTYPDQTFSLEIINEETPILGVPEYIAQLMDKLVANALEFSHPHTPIDVSLKLK
NKFAELRISNQGPALPENMAEQIFESMVSVRMQKAQDKPHLGLGLYIARLISQFHQGQINARNLQDKSGEISGVEIKIRL
PLSKETLP

Sequences:

>Translated_728_residues
MFNLPIGLRAKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGSDYQIYKRDESQPLQLSFTHMVGKYAGYLYAFFEVNDPQVVYRGKNSLSIDR
NDHIAIATLAPDGMFRRYIIATTQDGWISAFELPEDPSLSKPVTPEVKIQGKWTKSKQGYNVELRIPLDMVGSKLGFVVY
DVNDKHSRALDAAVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRSAIEKE
GNSTWEKFKRDYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQELNPDTRKYVDRAQEGVNRLNMILNNMSEATRL
EESLSHAEKTVFPLEKVVSGCMQGYQMTYPDQTFSLEIINEETPILGVPEYIAQLMDKLVANALEFSHPHTPIDVSLKLK
NKFAELRISNQGPALPENMAEQIFESMVSVRMQKAQDKPHLGLGLYIARLISQFHQGQINARNLQDKSGEISGVEIKIRL
PLSKETLP
>Mature_728_residues
MFNLPIGLRAKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERPKLFDSQASFLTQVEKGRDLY
AYPLSGPIQLDGKLADWSSYRHRALNYGSDYQIYKRDESQPLQLSFTHMVGKYAGYLYAFFEVNDPQVVYRGKNSLSIDR
NDHIAIATLAPDGMFRRYIIATTQDGWISAFELPEDPSLSKPVTPEVKIQGKWTKSKQGYNVELRIPLDMVGSKLGFVVY
DVNDKHSRALDAAVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLAKSGDIRSDNSVWSRSAIEKE
GNSTWEKFKRDYLHPLYYKILTTPAKDFIDSLQDSTVLQGSHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMG
VVIAEETTHGIRTLRNKALEKLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQELNPDTRKYVDRAQEGVNRLNMILNNMSEATRL
EESLSHAEKTVFPLEKVVSGCMQGYQMTYPDQTFSLEIINEETPILGVPEYIAQLMDKLVANALEFSHPHTPIDVSLKLK
NKFAELRISNQGPALPENMAEQIFESMVSVRMQKAQDKPHLGLGLYIARLISQFHQGQINARNLQDKSGEISGVEIKIRL
PLSKETLP

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=23.828125, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=24.7011952191235, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=356, Percent_Identity=19.3820224719101, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1790346, Length=282, Percent_Identity=23.0496453900709, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82009; Mature: 82009

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNLPIGLRAKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KLFDSQASFLTQVEKGRDLYAYPLSGPIQLDGKLADWSSYRHRALNYGSDYQIYKRDESQ
HHHHHHHHHHHHHHCCCCEEEECCCCCEEECCEECCHHHHHHHHCCCCCCCEEEECCCCC
PLQLSFTHMVGKYAGYLYAFFEVNDPQVVYRGKNSLSIDRNDHIAIATLAPDGMFRRYII
CEEEEHHHHHHHHHCEEEEEEEECCCEEEEECCCCEEECCCCCEEEEEECCCCCEEEEEE
ATTQDGWISAFELPEDPSLSKPVTPEVKIQGKWTKSKQGYNVELRIPLDMVGSKLGFVVY
EECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHCCCCCEEEE
DVNDKHSRALDAAVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLA
ECCCCHHHHHHHHHCCHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCEEEEEECCCEEEE
KSGDIRSDNSVWSRSAIEKEGNSTWEKFKRDYLHPLYYKILTTPAKDFIDSLQDSTVLQG
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC
SHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMGVVIAEETTHGIRTLRNKALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCEEEEEEECCHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQELNPDTRKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCHHHHHHHHH
QEGVNRLNMILNNMSEATRLEESLSHAEKTVFPLEKVVSGCMQGYQMTYPDQTFSLEIIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEEC
EETPILGVPEYIAQLMDKLVANALEFSHPHTPIDVSLKLKNKFAELRISNQGPALPENMA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHH
EQIFESMVSVRMQKAQDKPHLGLGLYIARLISQFHQGQINARNLQDKSGEISGVEIKIRL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEC
PLSKETLP
CCCCCCCC
>Mature Secondary Structure
MFNLPIGLRAKVAVLSLFLLCLPWLGYQYVWEMEKYLRHGQEKTLEGTTQALATALHERP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
KLFDSQASFLTQVEKGRDLYAYPLSGPIQLDGKLADWSSYRHRALNYGSDYQIYKRDESQ
HHHHHHHHHHHHHHCCCCEEEECCCCCEEECCEECCHHHHHHHHCCCCCCCEEEECCCCC
PLQLSFTHMVGKYAGYLYAFFEVNDPQVVYRGKNSLSIDRNDHIAIATLAPDGMFRRYII
CEEEEHHHHHHHHHCEEEEEEEECCCEEEEECCCCEEECCCCCEEEEEECCCCCEEEEEE
ATTQDGWISAFELPEDPSLSKPVTPEVKIQGKWTKSKQGYNVELRIPLDMVGSKLGFVVY
EECCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEECHHHHCCCCCEEEE
DVNDKHSRALDAAVGTSAIDDVSKLGTVLVPSPEIESIIKGMSHNSSRIWVVDKHGRVLA
ECCCCHHHHHHHHHCCHHHHHHHHCCEEECCCCHHHHHHHCCCCCCCEEEEEECCCEEEE
KSGDIRSDNSVWSRSAIEKEGNSTWEKFKRDYLHPLYYKILTTPAKDFIDSLQDSTVLQG
ECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEECC
SHISKALNGEQGSTWRLTPDNKAVVLAAASPIWIDDKVMGVVIAEETTHGIRTLRNKALE
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEECCCEEEEEEECCHHHHHHHHHHHHHH
KLFNVILTIMSMGTLALFFFASNISSRIRKLRDEAEQAIDSQGRIKNEIQGSKVRDEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHH
LSRSFASIVSRLSQYTHYLENMSSRLSHELRTPVAVVRSSLEHLGLQELNPDTRKYVDRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHCCCHHHHHHHHH
QEGVNRLNMILNNMSEATRLEESLSHAEKTVFPLEKVVSGCMQGYQMTYPDQTFSLEIIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEEEC
EETPILGVPEYIAQLMDKLVANALEFSHPHTPIDVSLKLKNKFAELRISNQGPALPENMA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHH
EQIFESMVSVRMQKAQDKPHLGLGLYIARLISQFHQGQINARNLQDKSGEISGVEIKIRL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEC
PLSKETLP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]