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The map label for this gene is wzb [C]

Identifier: 157962330

GI number: 157962330

Start: 3058044

End: 3058532

Strand: Reverse

Name: wzb [C]

Synonym: Spea_2509

Alternate gene names: 157962330

Gene position: 3058532-3058044 (Counterclockwise)

Preceding gene: 157962332

Following gene: 157962327

Centisome position: 59.11

GC content: 40.7

Gene sequence:

>489_bases
ATGAAACAAATTTCCTCGGTTCTATTTGTATGTATGGGCAACATATGTCGCTCTCCCTCTGCAGAAGCCATGTTCAGATC
AAAATCTCTAGCAGCTAGTTTAGATATTAAAATCGATTCAGCGGGAACGATTGCTTTTCATCAAGGGAATTCTCCGGATA
AACGATCGATTGCAGCAGGTATTAAGCGAGGTTTAAATTTTGATGGCATGAGAGCTAGGCAGGTTGAGCAAACTGACTTT
GCCGATTTTGATTTGATTCTTGCTGCGGATAAACAAAATCTTGAGGACTTGAAGCGAATATGTCCCACAGAGTACCAAGC
TAAATTGGCGTTAATTTTAGATTTCTGTGATTTTGACTATCACCAGAAAGCCTATACTGAAGTACCTGATCCATTCTATG
GTGCAGGCGACGGTTTTGAGTTAGTTCTGGATTTACTTGAAAACAGCTGTGATCAGCTTGTAAGACGCATCCAAAGAGGC
CGTTTGTAA

Upstream 100 bases:

>100_bases
TAGCTATCTGAAGTGGAGGGACAAGATAAATGTTACTTTCACAGATGTATGCGAAGATGGCTCATATCGGCTGATATTTA
GCCATGATTAAGGTTTTAGT

Downstream 100 bases:

>100_bases
CTGGTGAGTGGGTATAGAGAGGCGAGGAGCTAAATAAGCAGTGTTTGTTGCTATTAAGCTTTACTCAGTAAAAGGAAGAG
GATTAGATATTAAAAAGGCG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MKQISSVLFVCMGNICRSPSAEAMFRSKSLAASLDIKIDSAGTIAFHQGNSPDKRSIAAGIKRGLNFDGMRARQVEQTDF
ADFDLILAADKQNLEDLKRICPTEYQAKLALILDFCDFDYHQKAYTEVPDPFYGAGDGFELVLDLLENSCDQLVRRIQRG
RL

Sequences:

>Translated_162_residues
MKQISSVLFVCMGNICRSPSAEAMFRSKSLAASLDIKIDSAGTIAFHQGNSPDKRSIAAGIKRGLNFDGMRARQVEQTDF
ADFDLILAADKQNLEDLKRICPTEYQAKLALILDFCDFDYHQKAYTEVPDPFYGAGDGFELVLDLLENSCDQLVRRIQRG
RL
>Mature_162_residues
MKQISSVLFVCMGNICRSPSAEAMFRSKSLAASLDIKIDSAGTIAFHQGNSPDKRSIAAGIKRGLNFDGMRARQVEQTDF
ADFDLILAADKQNLEDLKRICPTEYQAKLALILDFCDFDYHQKAYTEVPDPFYGAGDGFELVLDLLENSCDQLVRRIQRG
RL

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=147, Percent_Identity=38.7755102040816, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI6005988, Length=139, Percent_Identity=39.568345323741, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1788375, Length=148, Percent_Identity=33.1081081081081, Blast_Score=77, Evalue=5e-16,
Organism=Escherichia coli, GI87081812, Length=157, Percent_Identity=29.9363057324841, Blast_Score=71, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=33.7662337662338, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706766, Length=159, Percent_Identity=33.9622641509434, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706768, Length=159, Percent_Identity=33.9622641509434, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78706770, Length=157, Percent_Identity=35.031847133758, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706772, Length=157, Percent_Identity=35.031847133758, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78706764, Length=131, Percent_Identity=35.8778625954198, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI78711846, Length=158, Percent_Identity=31.0126582278481, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18117; Mature: 18117

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQISSVLFVCMGNICRSPSAEAMFRSKSLAASLDIKIDSAGTIAFHQGNSPDKRSIAAG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCHHHHHHH
IKRGLNFDGMRARQVEQTDFADFDLILAADKQNLEDLKRICPTEYQAKLALILDFCDFDY
HHHCCCCCCCCHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCH
HQKAYTEVPDPFYGAGDGFELVLDLLENSCDQLVRRIQRGRL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQISSVLFVCMGNICRSPSAEAMFRSKSLAASLDIKIDSAGTIAFHQGNSPDKRSIAAG
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEECCCCEEEEECCCCCCHHHHHHH
IKRGLNFDGMRARQVEQTDFADFDLILAADKQNLEDLKRICPTEYQAKLALILDFCDFDY
HHHCCCCCCCCHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCH
HQKAYTEVPDPFYGAGDGFELVLDLLENSCDQLVRRIQRGRL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]