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The map label for this gene is pilH [H]

Identifier: 157962198

GI number: 157962198

Start: 2899423

End: 2899785

Strand: Direct

Name: pilH [H]

Synonym: Spea_2377

Alternate gene names: 157962198

Gene position: 2899423-2899785 (Clockwise)

Preceding gene: 157962195

Following gene: 157962206

Centisome position: 56.03

GC content: 42.7

Gene sequence:

>363_bases
ATGAATAAAGCAAAAATACTGGTTGTTGATGATGACCCTATTTGTTCGAGTCTTTTACTGTCAGTACTAGGCGATGACTA
CCAAGTCACCACGGTCAACTCTGGTGCTGATGTGATTGATATTGCAAATATCCAGCGACCCAATGTTATCTTTTTGGATA
TCATGATGCCGGGTAAAAATGGTTACCAAGTACTTAAAGATCTAAAGCAAGACCCGCAAACATCAAAGCTACCCGTTATT
ATTGTCAGTGCGCTTGCAGAGGAGTCCGATGAAAGTCTTGGGCTTAGACTCGGCGCAGATGGCTACCTAGCCAAGCCTAT
CAGTCCGAAAGAAGTGTTTGCTGTACTTAAGAAGTACCTCTAA

Upstream 100 bases:

>100_bases
TGATTAATAGCGTTAGAGTTAGCTAATATCCCTGTATAATGATAGGGTTATTACGTAAAGGTTGGAGCCCGATCGCAGGT
GAGTTTAGGAGTGTATCTGA

Downstream 100 bases:

>100_bases
TGAAGCTGAAGCCTACACAATAAAAACCATCTATTGCTAATTGCAAAACATTAATGATGTATACCGCTTGCGAAAAAGCT
ACGTTGACACTCTCTGCAGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MNKAKILVVDDDPICSSLLLSVLGDDYQVTTVNSGADVIDIANIQRPNVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALAEESDESLGLRLGADGYLAKPISPKEVFAVLKKYL

Sequences:

>Translated_120_residues
MNKAKILVVDDDPICSSLLLSVLGDDYQVTTVNSGADVIDIANIQRPNVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALAEESDESLGLRLGADGYLAKPISPKEVFAVLKKYL
>Mature_120_residues
MNKAKILVVDDDPICSSLLLSVLGDDYQVTTVNSGADVIDIANIQRPNVIFLDIMMPGKNGYQVLKDLKQDPQTSKLPVI
IVSALAEESDESLGLRLGADGYLAKPISPKEVFAVLKKYL

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=120, Percent_Identity=36.6666666666667, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=36.8421052631579, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=35.042735042735, Blast_Score=77, Evalue=4e-16,
Organism=Escherichia coli, GI1790860, Length=121, Percent_Identity=33.8842975206612, Blast_Score=72, Evalue=7e-15,
Organism=Escherichia coli, GI2367329, Length=117, Percent_Identity=41.025641025641, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1786911, Length=113, Percent_Identity=34.5132743362832, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=30.0884955752212, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=104, Percent_Identity=36.5384615384615, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=119, Percent_Identity=33.6134453781513, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=34.1880341880342, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13031; Mature: 13031

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAKILVVDDDPICSSLLLSVLGDDYQVTTVNSGADVIDIANIQRPNVIFLDIMMPGKN
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEEEECCCC
GYQVLKDLKQDPQTSKLPVIIVSALAEESDESLGLRLGADGYLAKPISPKEVFAVLKKYL
CHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNKAKILVVDDDPICSSLLLSVLGDDYQVTTVNSGADVIDIANIQRPNVIFLDIMMPGKN
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCEEEEEEEECCCC
GYQVLKDLKQDPQTSKLPVIIVSALAEESDESLGLRLGADGYLAKPISPKEVFAVLKKYL
CHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCEEECCCCCEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]