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The map label for this gene is queC [H]

Identifier: 157962170

GI number: 157962170

Start: 2861885

End: 2862568

Strand: Direct

Name: queC [H]

Synonym: Spea_2349

Alternate gene names: 157962170

Gene position: 2861885-2862568 (Clockwise)

Preceding gene: 157962168

Following gene: 157962171

Centisome position: 55.31

GC content: 44.44

Gene sequence:

>684_bases
ATGTCAAAAGCCGTTGTAGTTTTTAGTGGTGGTCAAGATTCGACAACCTGCCTCATCCAAGCCCTTCAACATTTTGATGA
GGTCCACGGGATCACCTTCGATTATGGACAAAGACATAGAGAAGAGATCGAAATTGCCAAAACACTGGCTAGCAAGCTTA
AATTGGCTAGTCACAAGGTGATGGACGTAACTCTACTCAATGAATTAGCCATCTCAGCGCTCACCCGTGACTCCATTCCG
GTCTCCAATGATTTAATGGATAACGGCCTACCAAATACCTTCGTTCCAGGGAGAAACATTCTGTTTCTAACGCTCGCTGG
GATCTATGCCTATCAGCTTGGTGCCGATGTTGTTATTACTGGTGTGTGTGAAACAGACTTCTCAGGCTATCCCGATTGTC
GTAATGACTTTGTAAAAGCGATGCAAGCGGCACTTGAGCAAGGTATGGACAAAAAGCTAACCATTCAAACGCCTTTAATG
TGGTTAGATAAAGCTGAAACTTGGGCTTTAGCGGATAAATACCAAAGCTTAGATCTAATCCGTGATGAGACGCTAACTTG
TTATAACGGAATTAAAGGTGATGGTTGCGGTACCTGCCCAGCCTGCCTATTAAGAAAGCGTGGGCTTGAAGAGTACCTAG
CCGATAAAGAGGCGATACAAGCAAGACTTACGGCTAAATGCTAA

Upstream 100 bases:

>100_bases
CATTTATAGTAGATTTTACTCAGAGTCGCAAGTAGTTTAAAAGCATTCACAGCTGAGCTAAACTACTCAGTCTTATTTAT
TGAAAGATTAAAGCTTAATT

Downstream 100 bases:

>100_bases
AACTCAAATTAGGGGCTAATAGCCCCTATGGGGTCGCGCTGGTCATCACCCTAGTTTGTGTCTGTTTTTTTTATTTGCAA
CTTGACGCTTTACTGGCCTA

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSKAVVVFSGGQDSTTCLIQALQHFDEVHGITFDYGQRHREEIEIAKTLASKLKLASHKVMDVTLLNELAISALTRDSIP
VSNDLMDNGLPNTFVPGRNILFLTLAGIYAYQLGADVVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLM
WLDKAETWALADKYQSLDLIRDETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLTAKC

Sequences:

>Translated_227_residues
MSKAVVVFSGGQDSTTCLIQALQHFDEVHGITFDYGQRHREEIEIAKTLASKLKLASHKVMDVTLLNELAISALTRDSIP
VSNDLMDNGLPNTFVPGRNILFLTLAGIYAYQLGADVVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLM
WLDKAETWALADKYQSLDLIRDETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLTAKC
>Mature_226_residues
SKAVVVFSGGQDSTTCLIQALQHFDEVHGITFDYGQRHREEIEIAKTLASKLKLASHKVMDVTLLNELAISALTRDSIPV
SNDLMDNGLPNTFVPGRNILFLTLAGIYAYQLGADVVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMW
LDKAETWALADKYQSLDLIRDETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLTAKC

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=69.1629955947137, Blast_Score=334, Evalue=3e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25032; Mature: 24901

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAVVVFSGGQDSTTCLIQALQHFDEVHGITFDYGQRHREEIEIAKTLASKLKLASHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVTLLNELAISALTRDSIPVSNDLMDNGLPNTFVPGRNILFLTLAGIYAYQLGADVVIT
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
GVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMWLDKAETWALADKYQSLDLI
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHH
RDETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLTAKC
HHCCHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKAVVVFSGGQDSTTCLIQALQHFDEVHGITFDYGQRHREEIEIAKTLASKLKLASHKV
CCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVTLLNELAISALTRDSIPVSNDLMDNGLPNTFVPGRNILFLTLAGIYAYQLGADVVIT
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
GVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMWLDKAETWALADKYQSLDLI
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHH
RDETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLTAKC
HHCCHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA