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The map label for this gene is fadE12 [H]

Identifier: 157961997

GI number: 157961997

Start: 2633042

End: 2634232

Strand: Direct

Name: fadE12 [H]

Synonym: Spea_2176

Alternate gene names: 157961997

Gene position: 2633042-2634232 (Clockwise)

Preceding gene: 157961996

Following gene: 157962001

Centisome position: 50.88

GC content: 44.16

Gene sequence:

>1191_bases
ATGAAACTCGATTTTGATAATGCAGATGAATGCTTTCGTCGCGATGTGAGTCAATGGCTTAGTGATAATTTAAGCGGTGA
ATTTGAATGTATTCGTGGCCGAGGTGGTCCTGGCGACGAGCATATGTTTATTGAAGAGCGTAAGGCTTGGGAGCGAAAAC
TATATCAAGGTGGCTGGACATGCATTGGCTGGCCAAAAGAGTACGGAGGAAAGGCGGCCAGCATAGTGCAGCAAGTTATT
TTTAACGAAGAATACGCAAGGGCTGGAGGCCCAGGCAGAATAGGCCATATAGGTGAAACTCTAATTGGGCCAACATTAAT
AGCCTATGGCAGTGAGCAACAAAAACGCCGTTATCTTGCGGGTATTTTAACCGGCACCGAATTTTGGTGTCAGGGGTACT
CTGAACCCAATGCTGGTTCTGACTTAGCTAACGTACATACCAAAGCTAAGTTTGATGATGAAACGGGCCAATGGTTAATA
AGCGGCCAGAAGGTGTGGACATCGTTAGCCCACGAATCCCATTATTGTTTCGTTGTCGCTAGAACCGATCCAAAGTCTGT
TGGCCAAAAAGGCTTGGGTTTCTTTTTAGTTAACATGGAGCAGCCTGAGGTCGATGTTAGACCCATAGCTCAAATGACAT
CAACCAGTGAATTCAATGAAGTTTTTTTTGATGATGCAGTATGTAGCAGCGATGATTTGGTTGGTCAATGTGGCGATGGT
TGGACAATTGCGATGAGTCTACTTGGATTTGAGCGTGGAATTTCAACTCTGGGTCAACAGATGCTTTTCACTAACGAGTT
CAACGATATAGTTAATGCAGCAAGAGCCAATGGGTCCGCTGATGATCCGATAATAAGGCAAAGAATTAGTGATGCGTATA
TTGGCTTAAAAATAATGCGCTATAACAGTATGCGTATGCTGTCAGATTCCAATGTTGACGGCGATTTATCTAAAGAGGCT
ATGTGCTATAAGCTTTACTGGGCGAGCTGGCACCGTAACTTAGGTAAACTTGCTATGGATGTACTTGGACCGGAGGCTGA
AATTTTACTCGACAGCCCCTATCAACTGACTCAGCTACAATCTATGTACCTTTTTTCTCGTTCAGATACCATCTATGGTG
GGACCAATCAAATCCAGCGCAATATTATTGCCGAGCGTGCTCTTGGAATGCCAAAAGAACCTAGAGGTTAA

Upstream 100 bases:

>100_bases
TTTATTTTAAACGAGCCAAATCCACAGAAACGTATTTAGGTAACGGTGCCTATCACCGCGAGCGTTTAGCTAATCTTATT
CTCCAGCCTGGAGCTTTATA

Downstream 100 bases:

>100_bases
AGGTAAGAGATAAGTAAGAGATAAGAGGTTAGTCGGCTAGCGAAAAATGCAATAAAAAGCCTGAAGAATATCTTCAGGCT
TTTTTATTACACGCTTAATA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKLDFDNADECFRRDVSQWLSDNLSGEFECIRGRGGPGDEHMFIEERKAWERKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGSEQQKRRYLAGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
SGQKVWTSLAHESHYCFVVARTDPKSVGQKGLGFFLVNMEQPEVDVRPIAQMTSTSEFNEVFFDDAVCSSDDLVGQCGDG
WTIAMSLLGFERGISTLGQQMLFTNEFNDIVNAARANGSADDPIIRQRISDAYIGLKIMRYNSMRMLSDSNVDGDLSKEA
MCYKLYWASWHRNLGKLAMDVLGPEAEILLDSPYQLTQLQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG

Sequences:

>Translated_396_residues
MKLDFDNADECFRRDVSQWLSDNLSGEFECIRGRGGPGDEHMFIEERKAWERKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGSEQQKRRYLAGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
SGQKVWTSLAHESHYCFVVARTDPKSVGQKGLGFFLVNMEQPEVDVRPIAQMTSTSEFNEVFFDDAVCSSDDLVGQCGDG
WTIAMSLLGFERGISTLGQQMLFTNEFNDIVNAARANGSADDPIIRQRISDAYIGLKIMRYNSMRMLSDSNVDGDLSKEA
MCYKLYWASWHRNLGKLAMDVLGPEAEILLDSPYQLTQLQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
>Mature_396_residues
MKLDFDNADECFRRDVSQWLSDNLSGEFECIRGRGGPGDEHMFIEERKAWERKLYQGGWTCIGWPKEYGGKAASIVQQVI
FNEEYARAGGPGRIGHIGETLIGPTLIAYGSEQQKRRYLAGILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLI
SGQKVWTSLAHESHYCFVVARTDPKSVGQKGLGFFLVNMEQPEVDVRPIAQMTSTSEFNEVFFDDAVCSSDDLVGQCGDG
WTIAMSLLGFERGISTLGQQMLFTNEFNDIVNAARANGSADDPIIRQRISDAYIGLKIMRYNSMRMLSDSNVDGDLSKEA
MCYKLYWASWHRNLGKLAMDVLGPEAEILLDSPYQLTQLQSMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=357, Percent_Identity=26.890756302521, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4501857, Length=352, Percent_Identity=25.2840909090909, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557231, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187960098, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=212, Percent_Identity=27.3584905660377, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4501859, Length=364, Percent_Identity=26.3736263736264, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI226958412, Length=245, Percent_Identity=25.7142857142857, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87081958, Length=342, Percent_Identity=24.8538011695906, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786223, Length=287, Percent_Identity=24.390243902439, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569725, Length=354, Percent_Identity=24.2937853107345, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=351, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=351, Percent_Identity=26.2108262108262, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=346, Percent_Identity=24.8554913294798, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=404, Percent_Identity=23.019801980198, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=214, Percent_Identity=30.3738317757009, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71990804, Length=218, Percent_Identity=27.9816513761468, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=203, Percent_Identity=31.5270935960591, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646207, Length=347, Percent_Identity=27.0893371757925, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24660351, Length=350, Percent_Identity=25.1428571428571, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355753, Length=353, Percent_Identity=23.2294617563739, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44358; Mature: 44358

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDFDNADECFRRDVSQWLSDNLSGEFECIRGRGGPGDEHMFIEERKAWERKLYQGGWT
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCE
CIGWPKEYGGKAASIVQQVIFNEEYARAGGPGRIGHIGETLIGPTLIAYGSEQQKRRYLA
EECCCHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHCCHHEECCCHHHHHHHHH
GILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLISGQKVWTSLAHESHYCFVVA
HHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEEEE
RTDPKSVGQKGLGFFLVNMEQPEVDVRPIAQMTSTSEFNEVFFDDAVCSSDDLVGQCGDG
CCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC
WTIAMSLLGFERGISTLGQQMLFTNEFNDIVNAARANGSADDPIIRQRISDAYIGLKIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEE
YNSMRMLSDSNVDGDLSKEAMCYKLYWASWHRNLGKLAMDVLGPEAEILLDSPYQLTQLQ
ECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
SMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
HHHHEECCCCEECCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLDFDNADECFRRDVSQWLSDNLSGEFECIRGRGGPGDEHMFIEERKAWERKLYQGGWT
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCE
CIGWPKEYGGKAASIVQQVIFNEEYARAGGPGRIGHIGETLIGPTLIAYGSEQQKRRYLA
EECCCHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHCCHHEECCCHHHHHHHHH
GILTGTEFWCQGYSEPNAGSDLANVHTKAKFDDETGQWLISGQKVWTSLAHESHYCFVVA
HHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCEEEEEEE
RTDPKSVGQKGLGFFLVNMEQPEVDVRPIAQMTSTSEFNEVFFDDAVCSSDDLVGQCGDG
CCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCC
WTIAMSLLGFERGISTLGQQMLFTNEFNDIVNAARANGSADDPIIRQRISDAYIGLKIMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEE
YNSMRMLSDSNVDGDLSKEAMCYKLYWASWHRNLGKLAMDVLGPEAEILLDSPYQLTQLQ
ECCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
SMYLFSRSDTIYGGTNQIQRNIIAERALGMPKEPRG
HHHHEECCCCEECCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]