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The map label for this gene is macB [H]

Identifier: 157961665

GI number: 157961665

Start: 2239346

End: 2240659

Strand: Direct

Name: macB [H]

Synonym: Spea_1841

Alternate gene names: 157961665

Gene position: 2239346-2240659 (Clockwise)

Preceding gene: 157961664

Following gene: 157961666

Centisome position: 43.28

GC content: 48.17

Gene sequence:

>1314_bases
ATGACCGCCAATAGAGCGCCGGTGAAGCTAGAAGCACAGTTCAACAAGGGCTCAATGAGTCCGTCTCGTCTACCTACCTC
AGTATATTGGGAAGGAATTAAGCAAGCTTTTGACGAGATGCGGCATCATAAACTCCGTACGTCATTAACCTTACTGGGGA
TGATATTCGGCGTAGGCGCAGTTATTGCTATGCTTAGTGTGGGTGAGGGGGCTGAGCGTGAAGCGCTTAAGATGATTGAA
TCTATGGGAGTGAAAAACCTAGTCGTCAATGCTCGCAGCGCCGAAGGCGATGCACTTAAGTCGATACGAGAGCACAGCAT
CGGTCTCAGTATTAGAGACGTAGAAAGTGCTCGTGATACCTTGCCATTTATAGACAATTGGAGCGCTGAGAAAAACGTAA
AAGTGTTCAGCTTGTTTAGCTTAAAAGGCCGCAGCGACGCACAAGTCGTAGGTGTGACGCCAAGTTATTTTGACTTGAGT
TCTTTACCTTTGGGAGAGGGACGAACGTTCAATGACAAGGATGAAGACTATTATCAACAAGTCGCGGTACTCGGCCCTGA
GGCTGCTAGGAGCTTATTCCCTCAAGGCAGTGCCATTGGTAATTTGGTTAAGGTTAATCATCAGTGGTTTACCGTTGTTG
GCGTGTTGTCAGAAAAAGAGAGCAGCAAGTCTAGCATTCAAGGAGTAAAGCTTGGCGGCGAGCGTAATCAAGTGTTTATT
CCTTTGACCACAGCGCTCAAAAAAATGCAGTTTAACAGTTTAGAGAGTGAGCTCGATGCATTTAAATTGGCATTGGCCGA
CGGTGTAGAGCCCTCGCTTGCAGCAAAAAGCTTACAGCATCTGCTAAATCGACGTCATGGCGGTGAAAAAGACTTTGATG
TGGTGGTGCCTGCCGACTTACTGGCCCAGCACCAAAAAACCCAGCAGATCTTCAACATTGTAATGGCCTGTGTCGCTGGG
ATTTCATTATTGGTTGGCGGGATCGGCATCATGAACATCATGTTAGCGACGATTTTAGAACGTACCGGTGAAATTGGTTT
GCTCAGGGCTCTGGGGGCAAAGCGTAAGGATATTGCCCGTCAATTCTTGATTGAGAGCATCGCGATATCGGCCACAGGTG
GCATCATAGGTATTGGTGTCGGATTGCTATTGGCCTTGATTATCTCCTCAGCTGCAGGCTGGCCTGTAGCATGGTCACCC
TTTGCCATCTTGTTGGCCCTTGGAGTTTGTATGACAATCGGTGTGGGATTTGGTCTGTATCCTGCCAACAAAGCCGCCAA
ACTTGACCCGATAGTGGCTCTGCAACGGGACTAG

Upstream 100 bases:

>100_bases
TTAAATTAGGTAACCGCAGCTTAAATAGAACGGTTGTTACTGAAGGATTAGAGCAAGGCGATACCATCGCGCTGACCACA
CCGCCGAAGAGGAATCGAGT

Downstream 100 bases:

>100_bases
TGGTTGCGTACTATTAAAATAACCCGCGATAACCTCGCGGGTTATTTTTTGTCTTTTTTGAGTAATCTTCTTTTGAAAAA
GGCTGACGAAGTTGTTTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTANRAPVKLEAQFNKGSMSPSRLPTSVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
SMGVKNLVVNARSAEGDALKSIREHSIGLSIRDVESARDTLPFIDNWSAEKNVKVFSLFSLKGRSDAQVVGVTPSYFDLS
SLPLGEGRTFNDKDEDYYQQVAVLGPEAARSLFPQGSAIGNLVKVNHQWFTVVGVLSEKESSKSSIQGVKLGGERNQVFI
PLTTALKKMQFNSLESELDAFKLALADGVEPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAG
ISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSP
FAILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD

Sequences:

>Translated_437_residues
MTANRAPVKLEAQFNKGSMSPSRLPTSVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIE
SMGVKNLVVNARSAEGDALKSIREHSIGLSIRDVESARDTLPFIDNWSAEKNVKVFSLFSLKGRSDAQVVGVTPSYFDLS
SLPLGEGRTFNDKDEDYYQQVAVLGPEAARSLFPQGSAIGNLVKVNHQWFTVVGVLSEKESSKSSIQGVKLGGERNQVFI
PLTTALKKMQFNSLESELDAFKLALADGVEPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAG
ISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSP
FAILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD
>Mature_436_residues
TANRAPVKLEAQFNKGSMSPSRLPTSVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGAVIAMLSVGEGAEREALKMIES
MGVKNLVVNARSAEGDALKSIREHSIGLSIRDVESARDTLPFIDNWSAEKNVKVFSLFSLKGRSDAQVVGVTPSYFDLSS
LPLGEGRTFNDKDEDYYQQVAVLGPEAARSLFPQGSAIGNLVKVNHQWFTVVGVLSEKESSKSSIQGVKLGGERNQVFIP
LTTALKKMQFNSLESELDAFKLALADGVEPSLAAKSLQHLLNRRHGGEKDFDVVVPADLLAQHQKTQQIFNIVMACVAGI
SLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIARQFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPF
AILLALGVCMTIGVGFGLYPANKAAKLDPIVALQRD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=425, Percent_Identity=31.7647058823529, Blast_Score=181, Evalue=9e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46980; Mature: 46849

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANRAPVKLEAQFNKGSMSPSRLPTSVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGA
CCCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAMLSVGEGAEREALKMIESMGVKNLVVNARSAEGDALKSIREHSIGLSIRDVESARDT
HHHHHHCCCCCHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHCCCEEEEHHHHHHC
LPFIDNWSAEKNVKVFSLFSLKGRSDAQVVGVTPSYFDLSSLPLGEGRTFNDKDEDYYQQ
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VAVLGPEAARSLFPQGSAIGNLVKVNHQWFTVVGVLSEKESSKSSIQGVKLGGERNQVFI
HHHCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEHHCCCCCHHHCCCEEECCCCCEEEE
PLTTALKKMQFNSLESELDAFKLALADGVEPSLAAKSLQHLLNRRHGGEKDFDVVVPADL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
LAQHQKTQQIFNIVMACVAGISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHH
QFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPFAILLALGVCMTIGVGFGLY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PANKAAKLDPIVALQRD
CCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TANRAPVKLEAQFNKGSMSPSRLPTSVYWEGIKQAFDEMRHHKLRTSLTLLGMIFGVGA
CCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAMLSVGEGAEREALKMIESMGVKNLVVNARSAEGDALKSIREHSIGLSIRDVESARDT
HHHHHHCCCCCHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHCCCEEEEHHHHHHC
LPFIDNWSAEKNVKVFSLFSLKGRSDAQVVGVTPSYFDLSSLPLGEGRTFNDKDEDYYQQ
CCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHH
VAVLGPEAARSLFPQGSAIGNLVKVNHQWFTVVGVLSEKESSKSSIQGVKLGGERNQVFI
HHHCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEHHCCCCCHHHCCCEEECCCCCEEEE
PLTTALKKMQFNSLESELDAFKLALADGVEPSLAAKSLQHLLNRRHGGEKDFDVVVPADL
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECHHH
LAQHQKTQQIFNIVMACVAGISLLVGGIGIMNIMLATILERTGEIGLLRALGAKRKDIAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHH
QFLIESIAISATGGIIGIGVGLLLALIISSAAGWPVAWSPFAILLALGVCMTIGVGFGLY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
PANKAAKLDPIVALQRD
CCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA