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The map label for this gene is yibH [H]

Identifier: 157961044

GI number: 157961044

Start: 1481454

End: 1482605

Strand: Direct

Name: yibH [H]

Synonym: Spea_1216

Alternate gene names: 157961044

Gene position: 1481454-1482605 (Clockwise)

Preceding gene: 157961043

Following gene: 157961045

Centisome position: 28.63

GC content: 47.66

Gene sequence:

>1152_bases
ATGAGTATGACTGAAGAAAAGGGTGTGACTGCGGACGAGGACGTTACAAAAGGTGAGCAGAGTAACGAGCCCGAAAAAGC
CGAGAACAACAAGAATACTAAAATTCGCAAAGCCACTAATATCATCTTAATCGTCGTCAGTTTCCTCTTCGTTTTTCATC
TTATCGCCGACCGATTTATCCCCTCAACCGATCTCGGTCGCATACGTGGCTATGTGGTTCCTATTGCCCCTCAGGTCTCT
GGCGAGATTGTTGATATCTTAGTTGAGCCTAACACCTTAATAAAACAAGGTGATGTACTCGCCAAGATTAATCCACAAGA
TTATGAAATTGCGCTGCAACAAGCGGAGCAATCACTCAAAAAGGCCGGACAAAATGTCGGTGCTCAAACGGCTAATGTTG
CCGCCGCTCAAGCTAAGGTCACCAATGCTCAGGCTAATCTAACCAATGCCCAAGTTCAGTCTAAGCGTATTTTTGCCATG
GTTGATAAAGCGGTTATGTCACAAGCTGATGCCGATAATGCCCGCGCCGAGCTGACAAAAGCAGAAGCTGGCGTTGCTAG
TGCTAAGGCCGATCTAGCCAAAGCCAAGGAACGTTTAGGCGCCGAAGGCGAGAATAATACTAATGTAAAATCGGCCCTAT
TGAGTCTAGAAAAAGCCCAGCTGGATCTAACCCGAACTTCTATTACGGCACCGACCAATGGCGTAGCCTCAAACTTTCGA
TTAAAAGAGGGGATTTACGCCAGTGCAGGCCAGCCAGTCATGACTTTTATCTCGTCGGAAGATGTGTGGATTGAGGCTTA
CTTTAGAGAAAACAGCTTAGGCAATATGCAGCCAGGTGACAAAGTTGAGTTTGCCCTCGATTATGCCCCAGGAAAGGTCT
TTCAAGCGACAGTTGGCAGCATAGATTACGGTATCGACTGGGGACAGAGTGAGCAGACGGGCAAGTTGGCACAAGTGTCA
GGCCAAACAGGCTGGTTGCGTCAGGCCCAGCGCTTTCCTGTCACGATCGTATTACCTGCAAAAGAAGCTATGGGCTTAAG
GCGCGTGGGTGGGCAGGTTGATGTAATTGTCTACACCAGTGACAGCAGTATCATTAATCTATTTGGTAAATTCTGGATCC
GCCTCGTGAGCTGGTTCTCTTATGTCAGATAG

Upstream 100 bases:

>100_bases
ACACTAAACTGATTAAAAACTAGCTGCATTATTTGAGAGTGAACAGGCTTTATGTGCTTGTTCATTTCGGCCAGATGCGA
GCTTGTCGGTGACTAAAGGA

Downstream 100 bases:

>100_bases
TCATCAACACCAGCGCTCATTTGCTTCAGCAAATAGGGGACATGCGACTGAAGAGGCCATTTATACTCGTAGAGTATTGC
GTTTCACCCTTGGGATAGGC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSMTEEKGVTADEDVTKGEQSNEPEKAENNKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPIAPQVS
GEIVDILVEPNTLIKQGDVLAKINPQDYEIALQQAEQSLKKAGQNVGAQTANVAAAQAKVTNAQANLTNAQVQSKRIFAM
VDKAVMSQADADNARAELTKAEAGVASAKADLAKAKERLGAEGENNTNVKSALLSLEKAQLDLTRTSITAPTNGVASNFR
LKEGIYASAGQPVMTFISSEDVWIEAYFRENSLGNMQPGDKVEFALDYAPGKVFQATVGSIDYGIDWGQSEQTGKLAQVS
GQTGWLRQAQRFPVTIVLPAKEAMGLRRVGGQVDVIVYTSDSSIINLFGKFWIRLVSWFSYVR

Sequences:

>Translated_383_residues
MSMTEEKGVTADEDVTKGEQSNEPEKAENNKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPIAPQVS
GEIVDILVEPNTLIKQGDVLAKINPQDYEIALQQAEQSLKKAGQNVGAQTANVAAAQAKVTNAQANLTNAQVQSKRIFAM
VDKAVMSQADADNARAELTKAEAGVASAKADLAKAKERLGAEGENNTNVKSALLSLEKAQLDLTRTSITAPTNGVASNFR
LKEGIYASAGQPVMTFISSEDVWIEAYFRENSLGNMQPGDKVEFALDYAPGKVFQATVGSIDYGIDWGQSEQTGKLAQVS
GQTGWLRQAQRFPVTIVLPAKEAMGLRRVGGQVDVIVYTSDSSIINLFGKFWIRLVSWFSYVR
>Mature_382_residues
SMTEEKGVTADEDVTKGEQSNEPEKAENNKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPIAPQVSG
EIVDILVEPNTLIKQGDVLAKINPQDYEIALQQAEQSLKKAGQNVGAQTANVAAAQAKVTNAQANLTNAQVQSKRIFAMV
DKAVMSQADADNARAELTKAEAGVASAKADLAKAKERLGAEGENNTNVKSALLSLEKAQLDLTRTSITAPTNGVASNFRL
KEGIYASAGQPVMTFISSEDVWIEAYFRENSLGNMQPGDKVEFALDYAPGKVFQATVGSIDYGIDWGQSEQTGKLAQVSG
QTGWLRQAQRFPVTIVLPAKEAMGLRRVGGQVDVIVYTSDSSIINLFGKFWIRLVSWFSYVR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=326, Percent_Identity=29.4478527607362, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790519, Length=291, Percent_Identity=31.6151202749141, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790012, Length=317, Percent_Identity=27.7602523659306, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789041, Length=329, Percent_Identity=24.6200607902736, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081951, Length=307, Percent_Identity=27.0358306188925, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789637, Length=307, Percent_Identity=27.3615635179153, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788711, Length=327, Percent_Identity=24.1590214067278, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787013, Length=238, Percent_Identity=27.7310924369748, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41591; Mature: 41459

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTEEKGVTADEDVTKGEQSNEPEKAENNKNTKIRKATNIILIVVSFLFVFHLIADRFI
CCCCCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PSTDLGRIRGYVVPIAPQVSGEIVDILVEPNTLIKQGDVLAKINPQDYEIALQQAEQSLK
CCCCCHHHCEEEEEECCCCCCCEEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHHHHH
KAGQNVGAQTANVAAAQAKVTNAQANLTNAQVQSKRIFAMVDKAVMSQADADNARAELTK
HHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AEAGVASAKADLAKAKERLGAEGENNTNVKSALLSLEKAQLDLTRTSITAPTNGVASNFR
HHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEHEEECCCCCCCCCCCE
LKEGIYASAGQPVMTFISSEDVWIEAYFRENSLGNMQPGDKVEFALDYAPGKVFQATVGS
ECCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEHHHCC
IDYGIDWGQSEQTGKLAQVSGQTGWLRQAQRFPVTIVLPAKEAMGLRRVGGQVDVIVYTS
EECCCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEECCHHHHHHHHCCCEEEEEEEEC
DSSIINLFGKFWIRLVSWFSYVR
CCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMTEEKGVTADEDVTKGEQSNEPEKAENNKNTKIRKATNIILIVVSFLFVFHLIADRFI
CCCCCCCCCCCCHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PSTDLGRIRGYVVPIAPQVSGEIVDILVEPNTLIKQGDVLAKINPQDYEIALQQAEQSLK
CCCCCHHHCEEEEEECCCCCCCEEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHHHHH
KAGQNVGAQTANVAAAQAKVTNAQANLTNAQVQSKRIFAMVDKAVMSQADADNARAELTK
HHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AEAGVASAKADLAKAKERLGAEGENNTNVKSALLSLEKAQLDLTRTSITAPTNGVASNFR
HHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEHEEECCCCCCCCCCCE
LKEGIYASAGQPVMTFISSEDVWIEAYFRENSLGNMQPGDKVEFALDYAPGKVFQATVGS
ECCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCEEEHHHCC
IDYGIDWGQSEQTGKLAQVSGQTGWLRQAQRFPVTIVLPAKEAMGLRRVGGQVDVIVYTS
EECCCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEECCHHHHHHHHCCCEEEEEEEEC
DSSIINLFGKFWIRLVSWFSYVR
CCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]