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The map label for this gene is glsA [H]

Identifier: 157960939

GI number: 157960939

Start: 1345820

End: 1346734

Strand: Direct

Name: glsA [H]

Synonym: Spea_1111

Alternate gene names: 157960939

Gene position: 1345820-1346734 (Clockwise)

Preceding gene: 157960938

Following gene: 157960940

Centisome position: 26.01

GC content: 46.12

Gene sequence:

>915_bases
ATGCCTGAATTGGCATTACTTGAAGAGGTCATCGAAAAAGTTCGGCCTCTTCTAGGACAGGGGAAAGTAGCTGATTATAT
TCCAGCGCTTGCCCAAGTCGATGCTAATAAGCTAGGTATTGCGGTGACAACCTCTGACGGTGTCACAATAGGGGCTGGAG
ATTATCTCGAGCCCTTTTCAATTCAGAGTATCTCTAAGGTATTTAGTCTTACCTTAGCGCTGATGTTGTATGAAGAAGAT
GAAATTTGGTCGAGAGTAGGTAAAGAACCCTCAGGCCATTCTTTTAACTCTTTAGTACAGGTTGAATTGGAAAAAGGCTT
ACCTCGAAATCCATTTATCAACGCTGGCGCGCTGGTCATTGCCGACCTTTTGCAAAGTCGCCTAGGTGCTCCTAAGCACC
GTATGCTTGAGATTGTTCGTCAGCTCAGTGAAAACCATCGCATAGGTTACGATAAAGTCGTTGCCGCGTCTGAGTATCAA
CACAGTGCAAGAAATGCTGCGATTGCTTACTTGATGAAGTCCTTTGGTAATTTCAACAATGATGTCGATACTGTGCTGCA
TAGCTATTTTCATTATTGTTCGCTGCGCATGAGCTGCGCAGATCTATCCCGTGCTATGTTTTACTTAGCAAACTCAGGTA
AGAGCCTTGCTGGTAAGCAACTTATTACGCCTGTGCAAAATCGGCAGCTAAATGCCTTATTAGCCACATCTGGTCTTTAT
GATGGTGCTGGTGAGTTCGCTTATCGTGTCGGTATGCCGGGTAAGAGCGGTGTCGGTGGTGGAATTATCGCGGTGATCCC
TGGCGATATGTCTGTGTGCGTTTGGTCCCCAGAGCTTGATGCCAACGGCAACTCTTTAGCGGGCACTGCTGTGTTAGAGG
CTTTGAGTCAGACTTTAGGTCGCTCAATTTTCTAG

Upstream 100 bases:

>100_bases
AGTGTACTGAAGAAAACAGAGCCGCTGTTAAGGCGTTCTTTGATGCACAACCAGTATCAGATCTTGAAATTGGTGAGCTT
TTCGATATCTGGTGGGGCTA

Downstream 100 bases:

>100_bases
TATTACTGTTCGACTTTGTTATATCTGCATCGATATCAGTACCTACACCAGTTGTTTGTGATATTTGGCTAATAGTTAGT
TTAATTGGCCAAATATCTTA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPELALLEEVIEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEED
EIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRQLSENHRIGYDKVVAASEYQ
HSARNAAIAYLMKSFGNFNNDVDTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLITPVQNRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLEALSQTLGRSIF

Sequences:

>Translated_304_residues
MPELALLEEVIEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEED
EIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRQLSENHRIGYDKVVAASEYQ
HSARNAAIAYLMKSFGNFNNDVDTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLITPVQNRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLEALSQTLGRSIF
>Mature_303_residues
PELALLEEVIEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFSIQSISKVFSLTLALMLYEEDE
IWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVIADLLQSRLGAPKHRMLEIVRQLSENHRIGYDKVVAASEYQH
SARNAAIAYLMKSFGNFNNDVDTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLITPVQNRQLNALLATSGLYD
GAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLEALSQTLGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=287, Percent_Identity=35.8885017421603, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=33.6734693877551, Blast_Score=162, Evalue=5e-40,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=64.4518272425249, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1786693, Length=289, Percent_Identity=35.9861591695502, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17532727, Length=302, Percent_Identity=33.4437086092715, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=294, Percent_Identity=36.3945578231293, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI193204073, Length=305, Percent_Identity=33.1147540983607, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=307, Percent_Identity=32.8990228013029, Blast_Score=157, Evalue=8e-39,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=35.7894736842105, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32724; Mature: 32593

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELALLEEVIEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCH
IQSISKVFSLTLALMLYEEDEIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLEIVRQLSENHRIGYDKVVAASEYQHSARNAAIAYLMKSFGNFNN
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLITPVQNRQLNALLATSGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCHHCCCHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLEALSQTLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC
>Mature Secondary Structure 
PELALLEEVIEKVRPLLGQGKVADYIPALAQVDANKLGIAVTTSDGVTIGAGDYLEPFS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCCCH
IQSISKVFSLTLALMLYEEDEIWSRVGKEPSGHSFNSLVQVELEKGLPRNPFINAGALVI
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHEEEEEHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLEIVRQLSENHRIGYDKVVAASEYQHSARNAAIAYLMKSFGNFNN
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLHSYFHYCSLRMSCADLSRAMFYLANSGKSLAGKQLITPVQNRQLNALLATSGLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCHHCCCHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPELDANGNSLAGTAVLEALSQTLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA