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The map label for this gene is nagA [H]

Identifier: 157960930

GI number: 157960930

Start: 1335168

End: 1336301

Strand: Direct

Name: nagA [H]

Synonym: Spea_1102

Alternate gene names: 157960930

Gene position: 1335168-1336301 (Clockwise)

Preceding gene: 157960929

Following gene: 157960931

Centisome position: 25.8

GC content: 48.5

Gene sequence:

>1134_bases
ATGAAGCAGACGATAATTGCCGACCGCGTATTCGATGGGCAGACATTTCATACAGATTTAGCCATCACTTTTGAAGATGG
TCATATTGTTTCATTCGACACAGTTCAAGGCGCCCATGAATCTCGCGTCAGTGGATTAATTGCACCGGGCTTTATCGATG
TGCAAGTCAACGGTGGTGGAGGGGTGTTGTTTAACTCCTCGCCAAATGTTGAGGGCATCGAAGCCATAGGTAAAGCCCAT
GCAAAGTTTGGCACGACGGCTTACTTACCAACACTCATTACCGATGATGTCGGTGTAATGCATAGGGCGGCTGACGCCGT
AGCATTAGCGCTTGAGTCGAACAGTGCTGGCGTGGTTGGAGTACATTTTGAGGGGCCTCATCTAAGCGTACCTAAAAAAG
GTGTGCATCCACAATCATATATCAGGCGGATCTCCGATGCCGAGTTGGCTATTTTCAGTCGCCAAGACATAGGCATTAAA
GTGGTAACGCTTGCACCTGAAAACGTCTCACCGGATGTCATTCAAGCTTTAGTCAAAGCCGGTGTAAAGGTATGTCTTGG
CCATTCCAATGCTGATTATGACACGGTCAAAGCGGCTCTTGCTGCTGGGGCGATAGGCTTTACCCATCTTTATAATGCGA
TGTCTGCACTGGACTCTAGAAACCCAGGAATGGTTGGGGCTGCACTCGAAAGCGCAGAAGCTTGGTGTGGCTTGATTGTA
GATGGTCATCATGTTCATCCCGCATCTGCACGAGTTGCTATCAATGCTAAACCTAAGGGTAAAGTCATGCTAGTGACCGA
TGCAATGCCTCCTGTTGGTGTAGATGAAGAGGTGAGCTTTGAGTTATTTGGCACTCAGGTATTAAGAGTGGGCGATAGGC
TGAATGCGGTGACGGGGGAGCTTGCAGGTTGTGTGCTGGATATGGCTGGAGCCGTGGCTAATACCGTCAATATGCTCGGG
CTAGCACCAGACGAGGCGTTAAGAATGGCTTCCTTGTATCCTGCCGAGTTTCTTGGCTTAAGTGATAAAATGGGTACGCT
ACAAGTTGGCGGGCGTGCAGATATGGTGTTACTGGATGACAAATACCGCGTAGATCAAACTTATATTGGTGGTGAGTTGG
TTTTTAAGGGCTAA

Upstream 100 bases:

>100_bases
TCTCCAAGCTTGCAGCCACCAGAGTGGGGCGCTGCATTTTTTGCTCAGCAGCAGTATACAAAAGCATAGCAGGGTCACTA
TTTTACTAAGTGGGAATAAG

Downstream 100 bases:

>100_bases
TCATCAATGCTTGTTTTAACTTAAACTGAGCCTCTGTAGTAAGTAATAACTTCAAATACTGCAGAGGCTTTGCTTTATGT
AGACGGCGATAAAAGCGATA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKQTIIADRVFDGQTFHTDLAITFEDGHIVSFDTVQGAHESRVSGLIAPGFIDVQVNGGGGVLFNSSPNVEGIEAIGKAH
AKFGTTAYLPTLITDDVGVMHRAADAVALALESNSAGVVGVHFEGPHLSVPKKGVHPQSYIRRISDAELAIFSRQDIGIK
VVTLAPENVSPDVIQALVKAGVKVCLGHSNADYDTVKAALAAGAIGFTHLYNAMSALDSRNPGMVGAALESAEAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGVDEEVSFELFGTQVLRVGDRLNAVTGELAGCVLDMAGAVANTVNMLG
LAPDEALRMASLYPAEFLGLSDKMGTLQVGGRADMVLLDDKYRVDQTYIGGELVFKG

Sequences:

>Translated_377_residues
MKQTIIADRVFDGQTFHTDLAITFEDGHIVSFDTVQGAHESRVSGLIAPGFIDVQVNGGGGVLFNSSPNVEGIEAIGKAH
AKFGTTAYLPTLITDDVGVMHRAADAVALALESNSAGVVGVHFEGPHLSVPKKGVHPQSYIRRISDAELAIFSRQDIGIK
VVTLAPENVSPDVIQALVKAGVKVCLGHSNADYDTVKAALAAGAIGFTHLYNAMSALDSRNPGMVGAALESAEAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGVDEEVSFELFGTQVLRVGDRLNAVTGELAGCVLDMAGAVANTVNMLG
LAPDEALRMASLYPAEFLGLSDKMGTLQVGGRADMVLLDDKYRVDQTYIGGELVFKG
>Mature_377_residues
MKQTIIADRVFDGQTFHTDLAITFEDGHIVSFDTVQGAHESRVSGLIAPGFIDVQVNGGGGVLFNSSPNVEGIEAIGKAH
AKFGTTAYLPTLITDDVGVMHRAADAVALALESNSAGVVGVHFEGPHLSVPKKGVHPQSYIRRISDAELAIFSRQDIGIK
VVTLAPENVSPDVIQALVKAGVKVCLGHSNADYDTVKAALAAGAIGFTHLYNAMSALDSRNPGMVGAALESAEAWCGLIV
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGVDEEVSFELFGTQVLRVGDRLNAVTGELAGCVLDMAGAVANTVNMLG
LAPDEALRMASLYPAEFLGLSDKMGTLQVGGRADMVLLDDKYRVDQTYIGGELVFKG

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=390, Percent_Identity=35.3846153846154, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI224922791, Length=410, Percent_Identity=33.9024390243902, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1786892, Length=377, Percent_Identity=39.5225464190981, Blast_Score=224, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17553768, Length=349, Percent_Identity=33.5243553008596, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI19920392, Length=389, Percent_Identity=36.5038560411311, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=34.9127182044888, Blast_Score=188, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39508; Mature: 39508

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTIIADRVFDGQTFHTDLAITFEDGHIVSFDTVQGAHESRVSGLIAPGFIDVQVNGGG
CCCCEEEEEEECCCEEEEEEEEEEECCEEEEECCCCCCHHHHHCCEECCCEEEEEEECCC
GVLFNSSPNVEGIEAIGKAHAKFGTTAYLPTLITDDVGVMHRAADAVALALESNSAGVVG
EEEECCCCCCHHHHHHHHHHHHCCCCEECCCHHCCCHHHHHHHCCEEEEEEECCCCCEEE
VHFEGPHLSVPKKGVHPQSYIRRISDAELAIFSRQDIGIKVVTLAPENVSPDVIQALVKA
EEECCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVKAALAAGAIGFTHLYNAMSALDSRNPGMVGAALESAEAWCGLIV
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEE
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGVDEEVSFELFGTQVLRVGDRLNAVTGE
ECCEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHCCHHHHHHHH
LAGCVLDMAGAVANTVNMLGLAPDEALRMASLYPAEFLGLSDKMGTLQVGGRADMVLLDD
HHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCEEEECC
KYRVDQTYIGGELVFKG
CEEECEEEECCEEEEEC
>Mature Secondary Structure
MKQTIIADRVFDGQTFHTDLAITFEDGHIVSFDTVQGAHESRVSGLIAPGFIDVQVNGGG
CCCCEEEEEEECCCEEEEEEEEEEECCEEEEECCCCCCHHHHHCCEECCCEEEEEEECCC
GVLFNSSPNVEGIEAIGKAHAKFGTTAYLPTLITDDVGVMHRAADAVALALESNSAGVVG
EEEECCCCCCHHHHHHHHHHHHCCCCEECCCHHCCCHHHHHHHCCEEEEEEECCCCCEEE
VHFEGPHLSVPKKGVHPQSYIRRISDAELAIFSRQDIGIKVVTLAPENVSPDVIQALVKA
EEECCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
GVKVCLGHSNADYDTVKAALAAGAIGFTHLYNAMSALDSRNPGMVGAALESAEAWCGLIV
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCEEEEEE
DGHHVHPASARVAINAKPKGKVMLVTDAMPPVGVDEEVSFELFGTQVLRVGDRLNAVTGE
ECCEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHCCHHHHHHHH
LAGCVLDMAGAVANTVNMLGLAPDEALRMASLYPAEFLGLSDKMGTLQVGGRADMVLLDD
HHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCEEEECC
KYRVDQTYIGGELVFKG
CEEECEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]