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The map label for this gene is hcr [H]

Identifier: 157960884

GI number: 157960884

Start: 1279439

End: 1280563

Strand: Direct

Name: hcr [H]

Synonym: Spea_1056

Alternate gene names: 157960884

Gene position: 1279439-1280563 (Clockwise)

Preceding gene: 157960883

Following gene: 157960885

Centisome position: 24.73

GC content: 45.87

Gene sequence:

>1125_bases
GTGAATGTTGCAGTCAATCATCAAGTTTCACAGCTTGCGCCATTTTCAGCTCAACAGTGGCAATCGGGTGAGCATCAATT
GGTTTGTGTTGAAAAGTGGAACGAAACTCACGATGTGATGAGCTTTCGTTTTCAGGGCTCTCAACCGGTAAAATTTCATT
TTAAGCCGGGGCAGTTTCTTACCCTGCTACTTGAGATTAATGGCGAGAAAATCGCACGAAGCTATACCATTAGTTCATCG
CCTTCACGCCCTTATTCCATTGTACTGACTATCAAGCGTATTGAAGGTGGCAAGGTTTCAAACTACTTAGCCGACAACCT
CGAAGTGGGGCACATTGTTCGCGCTTTGGGGCCTGACGGGGTATTTAACCTGGTTGATATTTCTGCTCAAAAATATCTAT
TTCTGAGTGCAGGCTGTGGTATTACGCCTATGTTCTCTATGTCTCGCTGGTTAACGGATACCGAAATCGGCCCAGATATC
AGCTTTTTACACAGTGCAAAGTCCAATAAAGATCTTATTTTTGAATCCGCTATTGCACAGATAGCTGAGCGTAGCGGTGA
TTTTAAGCTGAACTATATTTTGGAAGAGCTTGGTATATTCTCTAATATTGGGATCAGCGCTAAGTTTACCGACAAACAAG
CTGGGCGCTTAAATGCCGAAAACCTTGCGCGCCTCGTGCCTGACTTTAAAACGCGTACTGTATTTGTCTGCGGCCCAGCG
CCCTATATGAATGCGGTAAAGGCATTACTTGAGTCACTAGACTTTGATATGAGTCAGTTTCACCAAGAAAGCTTTGGCAG
TTTCAAAGGTGGCAGCGCAGAACTTGACGCTGCTAAAGAGCAAGCTACAAACAGTTCAACTGATCCAAGTGGCTTTATGC
TGAGTATTGGTGAAAGAAGCCGCGCTTTGTCCGCTGAACATACACTGCTCGATGGGATTGAGGCGGAAGGCTTACCCATT
ATTGCTGCTTGTCGCTCTGGTGTTTGTGGTGCATGTAAGTGCAAGGTTGTCAACGGCGAAGTGGAGTCATCAAGTCAAAT
GGCACTGACGCCCGACGAGATCGCTCAAGGCTACGTGCTTGCTTGCTCCAGCAAATTAAAGTCAGACGTAACACTAGAGC
TCTAG

Upstream 100 bases:

>100_bases
GCAAAGTTATTGGTGATAACTAAATCATAAATGGCCACCAATTAGTGGCCATTTTTTAGTTTTAAAATTTACTCGCTTTA
GGTGGGAAGGTAGGTATCGC

Downstream 100 bases:

>100_bases
TCTCTAGAGGCTCATGCTTTAAGTCTAACGCATGAAAATCTGAAATAAATCAGCTATGAAAGTTGCGTAACGCACAATGA
GAACGTAAGGTTAAAGACAG

Product: oxidoreductase FAD-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MNVAVNHQVSQLAPFSAQQWQSGEHQLVCVEKWNETHDVMSFRFQGSQPVKFHFKPGQFLTLLLEINGEKIARSYTISSS
PSRPYSIVLTIKRIEGGKVSNYLADNLEVGHIVRALGPDGVFNLVDISAQKYLFLSAGCGITPMFSMSRWLTDTEIGPDI
SFLHSAKSNKDLIFESAIAQIAERSGDFKLNYILEELGIFSNIGISAKFTDKQAGRLNAENLARLVPDFKTRTVFVCGPA
PYMNAVKALLESLDFDMSQFHQESFGSFKGGSAELDAAKEQATNSSTDPSGFMLSIGERSRALSAEHTLLDGIEAEGLPI
IAACRSGVCGACKCKVVNGEVESSSQMALTPDEIAQGYVLACSSKLKSDVTLEL

Sequences:

>Translated_374_residues
MNVAVNHQVSQLAPFSAQQWQSGEHQLVCVEKWNETHDVMSFRFQGSQPVKFHFKPGQFLTLLLEINGEKIARSYTISSS
PSRPYSIVLTIKRIEGGKVSNYLADNLEVGHIVRALGPDGVFNLVDISAQKYLFLSAGCGITPMFSMSRWLTDTEIGPDI
SFLHSAKSNKDLIFESAIAQIAERSGDFKLNYILEELGIFSNIGISAKFTDKQAGRLNAENLARLVPDFKTRTVFVCGPA
PYMNAVKALLESLDFDMSQFHQESFGSFKGGSAELDAAKEQATNSSTDPSGFMLSIGERSRALSAEHTLLDGIEAEGLPI
IAACRSGVCGACKCKVVNGEVESSSQMALTPDEIAQGYVLACSSKLKSDVTLEL
>Mature_374_residues
MNVAVNHQVSQLAPFSAQQWQSGEHQLVCVEKWNETHDVMSFRFQGSQPVKFHFKPGQFLTLLLEINGEKIARSYTISSS
PSRPYSIVLTIKRIEGGKVSNYLADNLEVGHIVRALGPDGVFNLVDISAQKYLFLSAGCGITPMFSMSRWLTDTEIGPDI
SFLHSAKSNKDLIFESAIAQIAERSGDFKLNYILEELGIFSNIGISAKFTDKQAGRLNAENLARLVPDFKTRTVFVCGPA
PYMNAVKALLESLDFDMSQFHQESFGSFKGGSAELDAAKEQATNSSTDPSGFMLSIGERSRALSAEHTLLDGIEAEGLPI
IAACRSGVCGACKCKVVNGEVESSSQMALTPDEIAQGYVLACSSKLKSDVTLEL

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=361, Percent_Identity=32.9639889196676, Blast_Score=181, Evalue=8e-47,
Organism=Escherichia coli, GI1787658, Length=362, Percent_Identity=29.2817679558011, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788903, Length=224, Percent_Identity=25.4464285714286, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323552, Length=196, Percent_Identity=25, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24662938, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281366101, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24662934, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40725; Mature: 40725

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAVNHQVSQLAPFSAQQWQSGEHQLVCVEKWNETHDVMSFRFQGSQPVKFHFKPGQFL
CCEECCCCHHHHCCCCHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCEE
TLLLEINGEKIARSYTISSSPSRPYSIVLTIKRIEGGKVSNYLADNLEVGHIVRALGPDG
EEEEEECCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHCCCCHHHHHHHCCCCC
VFNLVDISAQKYLFLSAGCGITPMFSMSRWLTDTEIGPDISFLHSAKSNKDLIFESAIAQ
CEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHH
IAERSGDFKLNYILEELGIFSNIGISAKFTDKQAGRLNAENLARLVPDFKTRTVFVCGPA
HHHCCCCEEEEHHHHHHCHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCC
PYMNAVKALLESLDFDMSQFHQESFGSFKGGSAELDAAKEQATNSSTDPSGFMLSIGERS
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCC
RALSAEHTLLDGIEAEGLPIIAACRSGVCGACKCKVVNGEVESSSQMALTPDEIAQGYVL
HHCCHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEECHHHHHCCEEE
ACSSKLKSDVTLEL
EECHHCCCCEEEEC
>Mature Secondary Structure
MNVAVNHQVSQLAPFSAQQWQSGEHQLVCVEKWNETHDVMSFRFQGSQPVKFHFKPGQFL
CCEECCCCHHHHCCCCHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCEE
TLLLEINGEKIARSYTISSSPSRPYSIVLTIKRIEGGKVSNYLADNLEVGHIVRALGPDG
EEEEEECCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHCCCCHHHHHHHCCCCC
VFNLVDISAQKYLFLSAGCGITPMFSMSRWLTDTEIGPDISFLHSAKSNKDLIFESAIAQ
CEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHH
IAERSGDFKLNYILEELGIFSNIGISAKFTDKQAGRLNAENLARLVPDFKTRTVFVCGPA
HHHCCCCEEEEHHHHHHCHHHCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEECCC
PYMNAVKALLESLDFDMSQFHQESFGSFKGGSAELDAAKEQATNSSTDPSGFMLSIGERS
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCC
RALSAEHTLLDGIEAEGLPIIAACRSGVCGACKCKVVNGEVESSSQMALTPDEIAQGYVL
HHCCHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCEEECHHHHHCCEEE
ACSSKLKSDVTLEL
EECHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]