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The map label for this gene is hlyB [H]

Identifier: 157960728

GI number: 157960728

Start: 1098306

End: 1100027

Strand: Direct

Name: hlyB [H]

Synonym: Spea_0900

Alternate gene names: 157960728

Gene position: 1098306-1100027 (Clockwise)

Preceding gene: 157960726

Following gene: 157960731

Centisome position: 21.23

GC content: 48.66

Gene sequence:

>1722_bases
ATGTCTGTATTAACTGAACAGTTAGGACGTGATGAGGTTCGACAACCTCACCAATCACAGTCTGGCTTTACCTCGCTTTT
CAAATCGGTACGATTTCAACTTAAACTTATTGTATTTCTGACCGTTATCTCATTCTTATTCTTAGGCTATAAAGGCATAT
CCGGTATGCAAGATGCCGGAGAGTCGATAGGCAAGCTGCATGCCCAGGGCATGCAGCATAGTATTCGTGCGGGTAAGGTG
CTTAACGAATTAGCGAGCGCACGCAGTGAATTGTTACTCGCGTTTCAACACGACCCAAGCAGTCAATTTGCTGAAATGCA
TAATCACCCGCTGACACAGCACATTACTCAAGCTCAAGCGGCAATCGCTCAGCTACATAATATTATTGATAATCAGATCT
TAGGGGCAAAACTAGATAACGAAGAGCGCCTGCAAGTTAACCGCTTAAAGGCCCAGCTCGATAATGTGGTGGCTCAAGGG
TTTAACCCAACTATAGATGCGCTTCAACGAGGCGAGTATGAGGCGGCAAATAGGGTGTTACTGACTCAGATCAACCCGCT
TTTTAAGAATATTAGCGCCGAGGCACAATCATTCTTAGAGATGCAGGTTGTTGAAGGTGAGCAGAGCTTTAGCCAATTTA
ATCAAGATATGCAGGTTTACATAGGGCTAGTTGCGGTCTTCTCTATCGTCAGTATGCTGGTTATTACAGTTAGCTCGACA
CTGATTGTTCGCCGTATGGGTAAGGCGATGACGGAGCTAGAGGAAACGGCAAATGATATTGCCAATGGTGATCTGACTAA
ACGTATCGTGATCGGCGGTGATGATGAGTTTACCCATATTGCCGACTATGTTAACCGGATAGCTGCGAGATTCCAGCATG
CGGTGCAAAATACCCACGAGTCGACTTCGCGTTTAGCCAGTGCGGCGGAAGAGAACTCGGTGGTATCGACGCAGACTCAA
CGCAATGTGGTTGAGCAGCAGCAACAGACGCAGCAAATTGCTGCTGCGATTCATCAATTTACCGCGACAGTGAGAGAAGT
GGCGCAAAGCGCAGAAGCCGCTGCCAGTTCGTCGTTAGAGGCTAACAGCGCGGCTCATCATGGTCAGGCTGTTGTCGATG
AGAGTATCGCGGTAATTGAGACCTTATCATCTGAGATGGACGGCGCGACTGAAGCGATGAAGTTACTGTCAAAGTCGTCT
GATGAGATTGGTTCGGTCGTCGATGTCATTCAAGGGATCTCAGAGCAGACTAATTTGCTCGCACTAAACGCGGCTATTGA
GGCTGCCCGTGCGGGTGAGCAGGGCCGAGGCTTTGCCGTTGTAGCCGATGAGGTGCGCTCGCTTGCTAAGCGAACCCAGG
ACTCGACTGAAGAAATTCAGCAGATGATCCAGCGTTTGCAGCAAGGTGCTCGTGACTCGATGCTGATGATGGATCGCGGT
ACCGAGCAGGCAAAACTGAGTGTTGACAAGTCACAGCAAGCTGGCGCTGCTTTACTGCAAATTATGGCCAGCATTGAGCA
GATCAATGCCTTGAATACACAGATTGCCACCGCGTCAGAAGAGCAGAGCCTAGTTACTGAAGAGATTAATCGTAATATTA
TCAATATCAGCGATATCTCGGACCAAACTGCAGCAGGCGCTGAGCAAACTCAGGCTGCTACCCATGAGCTCGCTCAGCTT
GCGGAATCTATGCAGCAAGAAATCGCCTATTATCGAGTGTGA

Upstream 100 bases:

>100_bases
TATGCTGCTCAAGCAGCGGTTTGGCTGTGGTAAGACGAGTGCACTAGATTTCGTTTTATTTTCATGATTCCATCAGTATT
GGTGGGGAACAGGAATTAGT

Downstream 100 bases:

>100_bases
CTCTAGTTTTTGTGTAGATTTCAGATAACAAAAAGGGCTGTCAGTGACAGCCCTTTATTATGAGCTAACTCCCGAGGAGG
AAGTTAGCTTTTCGACTAAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 572

Protein sequence:

>573_residues
MSVLTEQLGRDEVRQPHQSQSGFTSLFKSVRFQLKLIVFLTVISFLFLGYKGISGMQDAGESIGKLHAQGMQHSIRAGKV
LNELASARSELLLAFQHDPSSQFAEMHNHPLTQHITQAQAAIAQLHNIIDNQILGAKLDNEERLQVNRLKAQLDNVVAQG
FNPTIDALQRGEYEAANRVLLTQINPLFKNISAEAQSFLEMQVVEGEQSFSQFNQDMQVYIGLVAVFSIVSMLVITVSST
LIVRRMGKAMTELEETANDIANGDLTKRIVIGGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQ
RNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANSAAHHGQAVVDESIAVIETLSSEMDGATEAMKLLSKSS
DEIGSVVDVIQGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMDRG
TEQAKLSVDKSQQAGAALLQIMASIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQL
AESMQQEIAYYRV

Sequences:

>Translated_573_residues
MSVLTEQLGRDEVRQPHQSQSGFTSLFKSVRFQLKLIVFLTVISFLFLGYKGISGMQDAGESIGKLHAQGMQHSIRAGKV
LNELASARSELLLAFQHDPSSQFAEMHNHPLTQHITQAQAAIAQLHNIIDNQILGAKLDNEERLQVNRLKAQLDNVVAQG
FNPTIDALQRGEYEAANRVLLTQINPLFKNISAEAQSFLEMQVVEGEQSFSQFNQDMQVYIGLVAVFSIVSMLVITVSST
LIVRRMGKAMTELEETANDIANGDLTKRIVIGGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQ
RNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANSAAHHGQAVVDESIAVIETLSSEMDGATEAMKLLSKSS
DEIGSVVDVIQGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMDRG
TEQAKLSVDKSQQAGAALLQIMASIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQL
AESMQQEIAYYRV
>Mature_572_residues
SVLTEQLGRDEVRQPHQSQSGFTSLFKSVRFQLKLIVFLTVISFLFLGYKGISGMQDAGESIGKLHAQGMQHSIRAGKVL
NELASARSELLLAFQHDPSSQFAEMHNHPLTQHITQAQAAIAQLHNIIDNQILGAKLDNEERLQVNRLKAQLDNVVAQGF
NPTIDALQRGEYEAANRVLLTQINPLFKNISAEAQSFLEMQVVEGEQSFSQFNQDMQVYIGLVAVFSIVSMLVITVSSTL
IVRRMGKAMTELEETANDIANGDLTKRIVIGGDDEFTHIADYVNRIAARFQHAVQNTHESTSRLASAAEENSVVSTQTQR
NVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLEANSAAHHGQAVVDESIAVIETLSSEMDGATEAMKLLSKSSD
EIGSVVDVIQGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMDRGT
EQAKLSVDKSQQAGAALLQIMASIEQINALNTQIATASEEQSLVTEEINRNIINISDISDQTAAGAEQTQAATHELAQLA
ESMQQEIAYYRV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=31.9620253164557, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1788194, Length=379, Percent_Identity=29.023746701847, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787690, Length=491, Percent_Identity=26.2729124236253, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=31.3588850174216, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789453, Length=231, Percent_Identity=31.6017316017316, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62512; Mature: 62381

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLTEQLGRDEVRQPHQSQSGFTSLFKSVRFQLKLIVFLTVISFLFLGYKGISGMQDAG
CCHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ESIGKLHAQGMQHSIRAGKVLNELASARSELLLAFQHDPSSQFAEMHNHPLTQHITQAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHCCCHHHHHHHHHH
AIAQLHNIIDNQILGAKLDNEERLQVNRLKAQLDNVVAQGFNPTIDALQRGEYEAANRVL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHCCCH
LTQINPLFKNISAEAQSFLEMQVVEGEQSFSQFNQDMQVYIGLVAVFSIVSMLVITVSST
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIVRRMGKAMTELEETANDIANGDLTKRIVIGGDDEFTHIADYVNRIAARFQHAVQNTHE
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
STSRLASAAEENSVVSTQTQRNVVEQQQQTQQIAAAIHQFTATVREVAQSAEAAASSSLE
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ANSAAHHGQAVVDESIAVIETLSSEMDGATEAMKLLSKSSDEIGSVVDVIQGISEQTNLL
CCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ALNAAIEAARAGEQGRGFAVVADEVRSLAKRTQDSTEEIQQMIQRLQQGARDSMLMMDRG
HHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEHHCCC
TEQAKLSVDKSQQAGAALLQIMASIEQINALNTQIATASEEQSLVTEEINRNIINISDIS
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCC
DQTAAGAEQTQAATHELAQLAESMQQEIAYYRV
CHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]