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The map label for this gene is apaH [H]

Identifier: 157960688

GI number: 157960688

Start: 1058690

End: 1059523

Strand: Reverse

Name: apaH [H]

Synonym: Spea_0860

Alternate gene names: 157960688

Gene position: 1059523-1058690 (Counterclockwise)

Preceding gene: 157960689

Following gene: 157960687

Centisome position: 20.48

GC content: 44.72

Gene sequence:

>834_bases
ATGGCAAATTATTTTGTAGGTGATATACAAGGCTGTTTCGATGAGTTAATGCTACTTCTCGATAAAGTCGATTTTAATCC
ATCCAAAGACTGCTTATGGGCAGTAGGAGATCTCGTTGCAAGGGGGCCTGGCTCTCTGGAAACCCTGCGCTTCTTTAAGT
CGCTAGCTAACTCTGCAAAAGTCGTATTAGGCAATCACGATCTCCACTTGCTCGCCATTCATGGCAAGTTAAAGCGAGCC
AACCCTAAAGATCATTTAGCCGCATTGCTCGCAGCAGAAGACATTAACAATATTATCGACTGGCTAAGAATGCAGCCTCT
GTATCAGGAGTGCCCTGAACAACAGCTTATTATGACCCATGCTGGCGTACCACCAAATTGGGATCTGGCAACCCTGCACA
CAGAAGCAAATCGAGTCAGCGAAATCCTTAAGTCTAAGAACTATCTGCACGACTTAGTCAGCGAAATGTACACCAACTCT
GTCGACGAATATCGCTCGTCTCTATCGCCGTTAGAAAAGCAGATCTATTGCATTAATGCACTTACCCGCATGCGTTACCT
TAAACAAGATGGCCGCTTAGATTTCGACTGTAAGTCTCCAATTCAAAACTGTAACCATGCTGAACTGACACCTTGGTTTG
AGCTTGAGTCCAAATTACCTAGCGACTATACCTTAGTCTTTGGTCATTGGGCCGCCATTATGGGACAGACCAATCACCCT
AACCGCTTAGCTTTAGATACGGGCTGCTGTTGGGGAGAACACATGACCCTGTGGCATTTGGAGTCGAACCAGAAAATCAC
TCAAGAGAAATTAAAACACGTTAAAAGAAGTTAA

Upstream 100 bases:

>100_bases
TCGCTTATCTATCCCAGGCTTGCTTCATTAACATAACGGCTTTCCGTTTACCTGTTCCCAGTTTGATCCACTAACATAGA
AAAATAATATCTAGGTAAAA

Downstream 100 bases:

>100_bases
AAAAGAGTTAAGCTATTGCAACATTAGGCCGATAGACTATTCGAGGCCCTTGTCAGGTCGGTACTGAGATTTAGATAAAA
ATAATAATAAAATGGAGCTC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MANYFVGDIQGCFDELMLLLDKVDFNPSKDCLWAVGDLVARGPGSLETLRFFKSLANSAKVVLGNHDLHLLAIHGKLKRA
NPKDHLAALLAAEDINNIIDWLRMQPLYQECPEQQLIMTHAGVPPNWDLATLHTEANRVSEILKSKNYLHDLVSEMYTNS
VDEYRSSLSPLEKQIYCINALTRMRYLKQDGRLDFDCKSPIQNCNHAELTPWFELESKLPSDYTLVFGHWAAIMGQTNHP
NRLALDTGCCWGEHMTLWHLESNQKITQEKLKHVKRS

Sequences:

>Translated_277_residues
MANYFVGDIQGCFDELMLLLDKVDFNPSKDCLWAVGDLVARGPGSLETLRFFKSLANSAKVVLGNHDLHLLAIHGKLKRA
NPKDHLAALLAAEDINNIIDWLRMQPLYQECPEQQLIMTHAGVPPNWDLATLHTEANRVSEILKSKNYLHDLVSEMYTNS
VDEYRSSLSPLEKQIYCINALTRMRYLKQDGRLDFDCKSPIQNCNHAELTPWFELESKLPSDYTLVFGHWAAIMGQTNHP
NRLALDTGCCWGEHMTLWHLESNQKITQEKLKHVKRS
>Mature_276_residues
ANYFVGDIQGCFDELMLLLDKVDFNPSKDCLWAVGDLVARGPGSLETLRFFKSLANSAKVVLGNHDLHLLAIHGKLKRAN
PKDHLAALLAAEDINNIIDWLRMQPLYQECPEQQLIMTHAGVPPNWDLATLHTEANRVSEILKSKNYLHDLVSEMYTNSV
DEYRSSLSPLEKQIYCINALTRMRYLKQDGRLDFDCKSPIQNCNHAELTPWFELESKLPSDYTLVFGHWAAIMGQTNHPN
RLALDTGCCWGEHMTLWHLESNQKITQEKLKHVKRS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=273, Percent_Identity=43.956043956044, Blast_Score=244, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31671; Mature: 31539

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYFVGDIQGCFDELMLLLDKVDFNPSKDCLWAVGDLVARGPGSLETLRFFKSLANSAK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
VVLGNHDLHLLAIHGKLKRANPKDHLAALLAAEDINNIIDWLRMQPLYQECPEQQLIMTH
EEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHEEHHC
AGVPPNWDLATLHTEANRVSEILKSKNYLHDLVSEMYTNSVDEYRSSLSPLEKQIYCINA
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTRMRYLKQDGRLDFDCKSPIQNCNHAELTPWFELESKLPSDYTLVFGHWAAIMGQTNHP
HHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHCCCCCC
NRLALDTGCCWGEHMTLWHLESNQKITQEKLKHVKRS
CEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ANYFVGDIQGCFDELMLLLDKVDFNPSKDCLWAVGDLVARGPGSLETLRFFKSLANSAK
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCE
VVLGNHDLHLLAIHGKLKRANPKDHLAALLAAEDINNIIDWLRMQPLYQECPEQQLIMTH
EEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHEEHHC
AGVPPNWDLATLHTEANRVSEILKSKNYLHDLVSEMYTNSVDEYRSSLSPLEKQIYCINA
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTRMRYLKQDGRLDFDCKSPIQNCNHAELTPWFELESKLPSDYTLVFGHWAAIMGQTNHP
HHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHCCCCCC
NRLALDTGCCWGEHMTLWHLESNQKITQEKLKHVKRS
CEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA