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The map label for this gene is rpiA

Identifier: 157960644

GI number: 157960644

Start: 1013154

End: 1013813

Strand: Reverse

Name: rpiA

Synonym: Spea_0816

Alternate gene names: 157960644

Gene position: 1013813-1013154 (Counterclockwise)

Preceding gene: 157960647

Following gene: 157960642

Centisome position: 19.59

GC content: 46.21

Gene sequence:

>660_bases
ATGACTCAAGATGAAATGAAAAAAGCTGCCGGTTGGGCTGCGCTTCAGTACGTAGAAGAAAACAGCATTGTTGGTGTAGG
TACCGGCTCAACGGTCAATCACTTTATTGATGCACTAGCGACAATGAAGTTCGATATCGAAGGTGCAGTATCAAGCTCTG
AAGCGTCAACAGAGAAAATGAAGGCGTTAGGTATTCCCGTTTTTGACCTAAACAGCGTCAATGAGTTATCTGTTTATGTT
GATGGCGCCGACGAAATCAACAGCCAAATGGACATGATTAAAGGTGGCGGAGCAGCGCTGACTCGCGAGAAAATCGTTGC
CGCAGTTGCAGATAAGTTTATCTGTATCGTTGATAACACCAAGCAAGTCGACATTTTAGGTGAGTTCCCACTGCCAATCG
AAGTGATCCCAATGGCACGTTCATACGTGGCGCGCCAGATTGTTAAGCTGGGCGGAGATCCTGTTTACCGCGAAGGCTGT
GTTACCGATAACGGCAACATCATTATCGACGTGTACAACATGAAGATCATGAAGCCAAAAGAGCTAGAACAGCAGATTGA
CGGCATTGTTGGTGTAGTGACTAACGGCCTATTCGCTAAGCGCGGCGCTGATATTTTATTAGTTGGCACACCTGAAGGCG
TGAAGACAGTTACCTTTTAA

Upstream 100 bases:

>100_bases
AAGCAACTTTGCTTCGCTAAACGAGTATACTGTCGGCAATATTTCTATGCTTGCCTATAACTTTTATCTTTAACTTCTAT
CTTAAACAAAGGATTTCATA

Downstream 100 bases:

>100_bases
CGGGTTATCTAGTTCTCTCGTTATCTAAGCATTGAAAAGCCACTCATTTGAGTGGCTTTTTTGTTTACCATTTAAGGCGT
TAACTGAGAATGATAGAGTA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVNELSVYV
DGADEINSQMDMIKGGGAALTREKIVAAVADKFICIVDNTKQVDILGEFPLPIEVIPMARSYVARQIVKLGGDPVYREGC
VTDNGNIIIDVYNMKIMKPKELEQQIDGIVGVVTNGLFAKRGADILLVGTPEGVKTVTF

Sequences:

>Translated_219_residues
MTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVNELSVYV
DGADEINSQMDMIKGGGAALTREKIVAAVADKFICIVDNTKQVDILGEFPLPIEVIPMARSYVARQIVKLGGDPVYREGC
VTDNGNIIIDVYNMKIMKPKELEQQIDGIVGVVTNGLFAKRGADILLVGTPEGVKTVTF
>Mature_218_residues
TQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKMKALGIPVFDLNSVNELSVYVD
GADEINSQMDMIKGGGAALTREKIVAAVADKFICIVDNTKQVDILGEFPLPIEVIPMARSYVARQIVKLGGDPVYREGCV
TDNGNIIIDVYNMKIMKPKELEQQIDGIVGVVTNGLFAKRGADILLVGTPEGVKTVTF

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=210, Percent_Identity=37.6190476190476, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=72.8110599078341, Blast_Score=329, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI17551758, Length=210, Percent_Identity=37.1428571428571, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=226, Percent_Identity=30.0884955752212, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281364072, Length=205, Percent_Identity=35.1219512195122, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_SHEPA (A8H0Q6)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500678.1
- ProteinModelPortal:   A8H0Q6
- SMR:   A8H0Q6
- STRING:   A8H0Q6
- GeneID:   5661215
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_0816
- NMPDR:   fig|398579.3.peg.721
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- BioCyc:   SPEA398579:SPEA_0816-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23504; Mature: 23373

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKM
CCHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
KALGIPVFDLNSVNELSVYVDGADEINSQMDMIKGGGAALTREKIVAAVADKFICIVDNT
HHHCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
KQVDILGEFPLPIEVIPMARSYVARQIVKLGGDPVYREGCVTDNGNIIIDVYNMKIMKPK
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECEEEECHH
ELEQQIDGIVGVVTNGLFAKRGADILLVGTPEGVKTVTF
HHHHHHHHHHHHHHCCEECCCCCCEEEEECCCCCEEECC
>Mature Secondary Structure 
TQDEMKKAAGWAALQYVEENSIVGVGTGSTVNHFIDALATMKFDIEGAVSSSEASTEKM
CHHHHHHHHHHHHEEEECCCCEEEECCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHH
KALGIPVFDLNSVNELSVYVDGADEINSQMDMIKGGGAALTREKIVAAVADKFICIVDNT
HHHCCCEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEECCC
KQVDILGEFPLPIEVIPMARSYVARQIVKLGGDPVYREGCVTDNGNIIIDVYNMKIMKPK
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECEEEECHH
ELEQQIDGIVGVVTNGLFAKRGADILLVGTPEGVKTVTF
HHHHHHHHHHHHHHCCEECCCCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA