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The map label for this gene is fbp [H]

Identifier: 157960559

GI number: 157960559

Start: 906550

End: 907539

Strand: Reverse

Name: fbp [H]

Synonym: Spea_0731

Alternate gene names: 157960559

Gene position: 907539-906550 (Counterclockwise)

Preceding gene: 157960561

Following gene: 157960552

Centisome position: 17.54

GC content: 47.68

Gene sequence:

>990_bases
ATGCAAACTCTGGCTGAAAACCTGACATCACAAGCAATTTCTCCTACCCTTGAAAAACTTATCCTGACCCTAGCTAACAC
CTCAAAAGAGATTAGCCACGCAGTACGTCACGGCGCGCTAGCAGGCGTGTTAGGCGCAACGGAACAGGAAAACGTTCAAG
GCGAGACACAGAAGAAACTCGATATCATCACCAATGATATGCTCAAAGATGCCCTAAAGGCTGACGGTACAGTACGTGGT
ATCGCATCTGAAGAGGAAGACTATGTCGTTGAAGCCGATGCTAACGGCGAGTTTTTAGTGTGTTTTGACCCGCTAGACGG
CTCATCAAACATCGATATCAATTCACTAGTGGGTACTATCTTCTCAGTATTACCAGCTCCTGCCGGCGAGCTAACTGAAA
AGAGTTTCCTACAAGCAGGCCGCAACCAAGTGGCAGCAGGTTATGTGCTATACGGCCCATCAACCATGCTTGCACTGACT
ACAGGCCAAGGCGTACAACTATTTACCCTAAACCCAGAAACTAACGAGTTCTTGCTAACCAACGGCGCTATGGCGATTAG
TAAAGACACCGGCGAGTTTGCCATTAACATGTCAAACCAACGCTTCTGGGAAGCACCAATGCAGACTTACATCAGCGATC
TATTGCTAGGTAAGATTGGCCCACGTGAGAAGTCATTTAACATGCGCTGGATTGCCGCCATGGTGGGCGATGTACACCGC
GTACTTTGCCGCGGCGGTATCTTCACTTACCCAACTGACAACAAGAACCCAGAGAAGCCATACAAGCTACGTTTAATGTA
TGAAGCCAACCCAATGGCATTCTTGGTTGAGCAAGCAGGCGGTAAAGCATCGACGGGTTATGAAACCATTATGGATATTC
AGCCGACTGAAATTCACCAACGAGTAGCGGTGATCTTAGGCTCAGCCAATGAAGTTGACGCTTGTCTTGAATACCACGGT
ATTGATTACAGCGAAGAACCAGTTTTATAG

Upstream 100 bases:

>100_bases
AAACTAGCGTTCTGGGGTATCATCGCGTCAATAATAAAGAATACACTTTTGTCCTGACCTCAAACTCAATTTACTCATGT
AAAATTGTATAGGAAACAAG

Downstream 100 bases:

>100_bases
GTTCTAGGGGTTGAGATAGGTCCTAGGTCCTAGGTTCTACGCAAGGCTGAGACGGCAGGAGCCGAGAAAGCTTTGACGGT
GTCGGCCAAGACGGTAAAAG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGRNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNEFLLTNGAMAISKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIQPTEIHQRVAVILGSANEVDACLEYHG
IDYSEEPVL

Sequences:

>Translated_329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGRNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNEFLLTNGAMAISKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIQPTEIHQRVAVILGSANEVDACLEYHG
IDYSEEPVL
>Mature_329_residues
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKLDIITNDMLKDALKADGTVRG
IASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTIFSVLPAPAGELTEKSFLQAGRNQVAAGYVLYGPSTMLALT
TGQGVQLFTLNPETNEFLLTNGAMAISKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIQPTEIHQRVAVILGSANEVDACLEYHG
IDYSEEPVL

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=301, Percent_Identity=43.1893687707641, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI16579888, Length=301, Percent_Identity=43.1893687707641, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI22907028, Length=301, Percent_Identity=41.8604651162791, Blast_Score=233, Evalue=2e-61,
Organism=Escherichia coli, GI1790679, Length=323, Percent_Identity=43.0340557275542, Blast_Score=236, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17508131, Length=308, Percent_Identity=41.8831168831169, Blast_Score=234, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6323409, Length=297, Percent_Identity=40.4040404040404, Blast_Score=226, Evalue=3e-60,
Organism=Drosophila melanogaster, GI45550998, Length=320, Percent_Identity=39.0625, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI19921562, Length=320, Percent_Identity=39.0625, Blast_Score=202, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35802; Mature: 35802

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGIASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPAGELTEKSFLQAGRNQVAAGYVLYGPSTMLALTTGQGVQLFTLNPETNEFLLT
HHHHCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCCCEEEEE
NGAMAISKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
CCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIQPTEIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHEECCCHHHHHH
RVAVILGSANEVDACLEYHGIDYSEEPVL
HHHHEECCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQTLAENLTSQAISPTLEKLILTLANTSKEISHAVRHGALAGVLGATEQENVQGETQKKL
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DIITNDMLKDALKADGTVRGIASEEEDYVVEADANGEFLVCFDPLDGSSNIDINSLVGTI
HHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHH
FSVLPAPAGELTEKSFLQAGRNQVAAGYVLYGPSTMLALTTGQGVQLFTLNPETNEFLLT
HHHHCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCEEEEEECCCCCEEEEE
NGAMAISKDTGEFAINMSNQRFWEAPMQTYISDLLLGKIGPREKSFNMRWIAAMVGDVHR
CCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VLCRGGIFTYPTDNKNPEKPYKLRLMYEANPMAFLVEQAGGKASTGYETIMDIQPTEIHQ
HHHCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHEECCCHHHHHH
RVAVILGSANEVDACLEYHGIDYSEEPVL
HHHHEECCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA