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The map label for this gene is mdtB [H]

Identifier: 157825693

GI number: 157825693

Start: 561574

End: 561978

Strand: Reverse

Name: mdtB [H]

Synonym: A1C_03095

Alternate gene names: 157825693

Gene position: 561978-561574 (Counterclockwise)

Preceding gene: 157825694

Following gene: 157825684

Centisome position: 45.65

GC content: 38.52

Gene sequence:

>405_bases
ATGCAGCGGCACAAGACGTACAAGCAGCTACCGCACAACTTACCTACTCCACCCTCATATCGTAAAGTAAATCATGCTGA
TATACCCATATTTTATTTATCTTTAACCTCTGATACTCTCCCTTTATATACTGTGGACTATTACGCTGAAACAATTATAC
CTGAACATTTATCAATGTTACCGTGTGTTGCACATGTACAAGTGTACGGCTCACAACAATCTGCAGTGCGTGTACAAATT
GATCCGGTTAAGATGGAAGCAAATAATCTATGGCTTAACCAAGTATCGAATATTATCAGCTCTGCTGACGTTAATTTACC
GACTGGAGCTTTATACGGTAAAGATATCTACTCGAGCATTAGAGCCACGGGCAACTACAAAATGCTAAAGAATATAATGA
TTTAA

Upstream 100 bases:

>100_bases
AAGTAGTTCTCTAGGATATCCGATATTGATTCGATGAGTTCGGTTAACAGTAACTGCACTACTCAAATTACTTTGCAGTT
TAATTTAGAGCGTGATATAG

Downstream 100 bases:

>100_bases
TATTAACTTATAAAAACGGTAATCCGCTTTTTCTTAAAAAGATCGGTAAAACCATCGATAACGTAGCTCACAATCAAATA
TCCGCTTGGAGAGATAAACC

Product: RND family efflux transporter

Products: NA

Alternate protein names: Multidrug transporter MdtB [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MQRHKTYKQLPHNLPTPPSYRKVNHADIPIFYLSLTSDTLPLYTVDYYAETIIPEHLSMLPCVAHVQVYGSQQSAVRVQI
DPVKMEANNLWLNQVSNIISSADVNLPTGALYGKDIYSSIRATGNYKMLKNIMI

Sequences:

>Translated_134_residues
MQRHKTYKQLPHNLPTPPSYRKVNHADIPIFYLSLTSDTLPLYTVDYYAETIIPEHLSMLPCVAHVQVYGSQQSAVRVQI
DPVKMEANNLWLNQVSNIISSADVNLPTGALYGKDIYSSIRATGNYKMLKNIMI
>Mature_134_residues
MQRHKTYKQLPHNLPTPPSYRKVNHADIPIFYLSLTSDTLPLYTVDYYAETIIPEHLSMLPCVAHVQVYGSQQSAVRVQI
DPVKMEANNLWLNQVSNIISSADVNLPTGALYGKDIYSSIRATGNYKMLKNIMI

Specific function: Could Be A Drug Efflux Pump (By Similarity). [C]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788390, Length=104, Percent_Identity=38.4615384615385, Blast_Score=73, Evalue=8e-15,
Organism=Escherichia coli, GI1788391, Length=102, Percent_Identity=38.2352941176471, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR022831 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 15194; Mature: 15194

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRHKTYKQLPHNLPTPPSYRKVNHADIPIFYLSLTSDTLPLYTVDYYAETIIPEHLSML
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHH
PCVAHVQVYGSQQSAVRVQIDPVKMEANNLWLNQVSNIISSADVNLPTGALYGKDIYSSI
HHHHEEEEECCCCCEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCCEECHHHHHHH
RATGNYKMLKNIMI
HCCCCHHHHHHHCC
>Mature Secondary Structure
MQRHKTYKQLPHNLPTPPSYRKVNHADIPIFYLSLTSDTLPLYTVDYYAETIIPEHLSML
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHHHHHHHHH
PCVAHVQVYGSQQSAVRVQIDPVKMEANNLWLNQVSNIISSADVNLPTGALYGKDIYSSI
HHHHEEEEECCCCCEEEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCCCEECHHHHHHH
RATGNYKMLKNIMI
HCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA