Click here to switch to the map view.

The map label for this gene is ctaC [H]

Identifier: 157825684

GI number: 157825684

Start: 549578

End: 550519

Strand: Reverse

Name: ctaC [H]

Synonym: A1C_03030

Alternate gene names: 157825684

Gene position: 550519-549578 (Counterclockwise)

Preceding gene: 157825693

Following gene: 157825683

Centisome position: 44.72

GC content: 35.99

Gene sequence:

>942_bases
ATGAAAAATATTACTAGACATCTTTCCAAACCAGCTTATATAGAGGCATTTAAAGGAGGCCCGGAAGTGCTTGCCACCAT
AGACATATGTAAGGATACGAGTCTAGACTTGACGTCTAAATTACCTCTAGAAACGAATTTTGGGAAGATCTCGATTGTTT
TAATTTGTTTTGTGATTGTTAGTAGTAATTGCTTTGCCTCCGAGCCGTTACCTTGGCAAGTAACGTTCCAGCCTCCAGCA
AGTCCGATTATGGAGGAATTACATCATTTTCATAATTTTCTGCTTTATATCTCAACAGCTATTGTTTTATTTGTTGCTGG
ATTACTTGGCTTTGTATGTATCAGATTTAATGCAAAAAATAACCCTGTACCGGCAAAATTTTCACATAATATTTTAATAG
AAATAATTTGGACTGTAATACCTATTATAATTTTAGTTATTATTGCAGTACCGTCTTTTAGAATATTGCGTCATGCTGAA
AAAATACCCGAGACAGATTTAACTATTAAAGTAGTAGGTTATCAATGGTATTGGCATTATATATATCCTGATCATGATAA
TTTAGAATTTGATAGCGTAATGATCTCTGATGAGAATCTAAAACCTGACCAGAAACGATTATTGGATGTTGATAATCGAA
TTATTATCCCTGAAAATGCTACCGTAAGATTTCTCATTACCGCAGGTGATGTAATACATAGTTTTGCTGTTCCGTCACTT
GGTTTTAAAATAGACGCAGTCCCAGGCAGAATAAATGAAACCTGGACACGAGTAGCGAAAAAAGGCGTATATTACGGACA
ATGCTCTGAACTATGCGGCATCAATCACGGCTTCATGCCGATTGCTATAGAAGTAGTAAGTAAAGAGGATTTCGACAGTT
GGATTGCAAGCAAGAACAAGAAGAGCATGAATAGCGAGAAGCCAAAATTGGCGGCTAACTAA

Upstream 100 bases:

>100_bases
TATTAAAAATGTGTAGCTTTTACAAAAATTTATCGATTTTTACTTTAATAAAACTGTATATACATATATATTATATATAG
GAATAACTTATATATGTGCT

Downstream 100 bases:

>100_bases
TTATATGATAATAAGTGAAAAAGAATAAATCATCATGATATAGCTGATTAGCCTGAGTGGGAAAAACTTTTTTTATCTTA
TAGTATGTAGGGCGTTATGA

Product: cytochrome c oxidase polypeptide II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKNITRHLSKPAYIEAFKGGPEVLATIDICKDTSLDLTSKLPLETNFGKISIVLICFVIVSSNCFASEPLPWQVTFQPPA
SPIMEELHHFHNFLLYISTAIVLFVAGLLGFVCIRFNAKNNPVPAKFSHNILIEIIWTVIPIIILVIIAVPSFRILRHAE
KIPETDLTIKVVGYQWYWHYIYPDHDNLEFDSVMISDENLKPDQKRLLDVDNRIIIPENATVRFLITAGDVIHSFAVPSL
GFKIDAVPGRINETWTRVAKKGVYYGQCSELCGINHGFMPIAIEVVSKEDFDSWIASKNKKSMNSEKPKLAAN

Sequences:

>Translated_313_residues
MKNITRHLSKPAYIEAFKGGPEVLATIDICKDTSLDLTSKLPLETNFGKISIVLICFVIVSSNCFASEPLPWQVTFQPPA
SPIMEELHHFHNFLLYISTAIVLFVAGLLGFVCIRFNAKNNPVPAKFSHNILIEIIWTVIPIIILVIIAVPSFRILRHAE
KIPETDLTIKVVGYQWYWHYIYPDHDNLEFDSVMISDENLKPDQKRLLDVDNRIIIPENATVRFLITAGDVIHSFAVPSL
GFKIDAVPGRINETWTRVAKKGVYYGQCSELCGINHGFMPIAIEVVSKEDFDSWIASKNKKSMNSEKPKLAAN
>Mature_313_residues
MKNITRHLSKPAYIEAFKGGPEVLATIDICKDTSLDLTSKLPLETNFGKISIVLICFVIVSSNCFASEPLPWQVTFQPPA
SPIMEELHHFHNFLLYISTAIVLFVAGLLGFVCIRFNAKNNPVPAKFSHNILIEIIWTVIPIIILVIIAVPSFRILRHAE
KIPETDLTIKVVGYQWYWHYIYPDHDNLEFDSVMISDENLKPDQKRLLDVDNRIIIPENATVRFLITAGDVIHSFAVPSL
GFKIDAVPGRINETWTRVAKKGVYYGQCSELCGINHGFMPIAIEVVSKEDFDSWIASKNKKSMNSEKPKLAAN

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=220, Percent_Identity=44.5454545454545, Blast_Score=199, Evalue=4e-51,
Organism=Escherichia coli, GI1786635, Length=226, Percent_Identity=27.4336283185841, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=236, Percent_Identity=41.5254237288136, Blast_Score=199, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR005728 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35307; Mature: 35307

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNITRHLSKPAYIEAFKGGPEVLATIDICKDTSLDLTSKLPLETNFGKISIVLICFVIV
CCCHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SSNCFASEPLPWQVTFQPPASPIMEELHHFHNFLLYISTAIVLFVAGLLGFVCIRFNAKN
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
NPVPAKFSHNILIEIIWTVIPIIILVIIAVPSFRILRHAEKIPETDLTIKVVGYQWYWHY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEEEEEEE
IYPDHDNLEFDSVMISDENLKPDQKRLLDVDNRIIIPENATVRFLITAGDVIHSFAVPSL
EECCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEECCCCEEEEEEECCHHHHHHCCCCC
GFKIDAVPGRINETWTRVAKKGVYYGQCSELCGINHGFMPIAIEVVSKEDFDSWIASKNK
CEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEEECCCCHHHHHHCCCC
KSMNSEKPKLAAN
CCCCCCCCCCCCC
>Mature Secondary Structure
MKNITRHLSKPAYIEAFKGGPEVLATIDICKDTSLDLTSKLPLETNFGKISIVLICFVIV
CCCHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SSNCFASEPLPWQVTFQPPASPIMEELHHFHNFLLYISTAIVLFVAGLLGFVCIRFNAKN
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
NPVPAKFSHNILIEIIWTVIPIIILVIIAVPSFRILRHAEKIPETDLTIKVVGYQWYWHY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEEEEEEE
IYPDHDNLEFDSVMISDENLKPDQKRLLDVDNRIIIPENATVRFLITAGDVIHSFAVPSL
EECCCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEECCCCEEEEEEECCHHHHHHCCCCC
GFKIDAVPGRINETWTRVAKKGVYYGQCSELCGINHGFMPIAIEVVSKEDFDSWIASKNK
CEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHCCCCCCEEEEEEEECCCCHHHHHHCCCC
KSMNSEKPKLAAN
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]