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The map label for this gene is aprE [H]

Identifier: 157825557

GI number: 157825557

Start: 428725

End: 430260

Strand: Reverse

Name: aprE [H]

Synonym: A1C_02340

Alternate gene names: 157825557

Gene position: 430260-428725 (Counterclockwise)

Preceding gene: 157825558

Following gene: 157825556

Centisome position: 34.95

GC content: 33.33

Gene sequence:

>1536_bases
ATGCAGGATTTAAAACACAATAAACCTCAAATTACGCCGGAACAATTGAAACAATTATTATCCTTAAGGGAAGATGCGTT
AAACCTTAAAGGTCACAATTCTAAACGTATGACTTTAATAAATACTACATTAAAGAAAACCTCTCATGCTATAGAATTCT
TATTAGTCAAACTTGATAGATTTGTTAATTTTATTACCAAGAAAACCGATAAAGATCGTAATAACGTAGCCCAAGCTGCA
AGGTCACCTATACTTTTTGGTATTTATGTTATTATCTTTTTAGTATTAATAGGCGGATTATGGTCGGCTCTTGCTCCACT
TGATAGTGGTGCTGTAGCTGTCGGCATCGTAATCCCAAGCACAAATAAAAAAACGATTCAACATAATGAAGGTGGAATAA
TTAATGCTATTTACGTTAAGCAAGGTGATAAAGTCAAAGAAGGCGATAAATTAATAGAACTTGAAGAAACTAGAATCAAA
AGCGAACATGAAAATGTTCTTGGTCAGTACCGTAATTTTTTAGCAACTGAAAACCGTTTAATTGCCGAACGTGATCATTT
AGAACAAATTGAATTCTCGGATTTTCTAATGCATGATATAAATTTACCGGAAGTAGCTAAAATAATTCATACACAGGAAA
ATTTATTTAGATCTAGAAAAGAAGTATATAACTCAGAGAAAGATGCATTATATCAAAACATTGCTCAACTTGAGAAAAAA
ATTGAAGGTTTAGAGGCAAAAAAAGTTGCCGCTTTAAAAACTGCTGAAGTTTATCAAGACCGTTTAAAAGCTTTAAGAAC
GTTAAAAGAAAAAGGCTTTGTACAAAAAGCAGCATTATTAGACCAAGAGGCAAAAGTTGCCGCTTCAAAAAGCGATGTTG
CAACAACTGAAGCCGAAATAGCAGGGATACGCCATGCTATTACCGAAACTCAAATTAAAATTATAAATCAACAAAATAAA
TACACTGAACGGACTTTAACAGAGCTTCGCGAAGCTCAAGTACAAACAGCATCTCTTAAAGAAAAATATAATTCCCTGAC
GGATTCACTTAATCGTGTGATAATAAGATCACCCGTTGACGGTATAGTGAATAATTTAAAATATCATACAATAGGTGGTG
TTATAAGTCACGGACAACCTATTATGGAAATTTCGCCAATTAATGACCCATTAATAATAGAAGCAAAGGTATCTCAAAAA
AACATTGACTCAGTACATGAGGGATTAGTTGCAAAAATACGTTTCAGCGCATTTAAATCAAGAACAACTCCAACATTTAC
CGGTAAAGTAGTCAGCATATCGCCCGATATAGTACAAGATGAAAGACAACATCCGGGACAACAGCAAGATAATTATTATG
TTGCAAGAATTGAAATCGATATGGATGCATTTGATAAAGTTGCTAAAGTTAAAAATTTGGAATTACACCCAGGTATGCAA
GCTGAGGTACAAATCGTAACCGGTACTAGAACACTACTTAGATATTTACTTGATCCTATTACTGATACTGCATTTAAAGC
TTTCAGAGAAAAATAG

Upstream 100 bases:

>100_bases
CCACGGTGTGACAATACAGTGGATTTCACCGAGCTATGCTGGAATGACATCAAAAACAACGCAGACAGACAATGACTACA
TATAATAGTGATTAAATATT

Downstream 100 bases:

>100_bases
ATAATTTAAAAATTTTATGTTAGATCACTTTAGATAATCTAGATATTTTGTAACAATATTTATTAAAGATTCTTAATCCT
TTATTGACTTTTAACCAAAA

Product: alkaline protease secretion protein AprE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGHNSKRMTLINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVIIFLVLIGGLWSALAPLDSGAVAVGIVIPSTNKKTIQHNEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENVLGQYRNFLATENRLIAERDHLEQIEFSDFLMHDINLPEVAKIIHTQENLFRSRKEVYNSEKDALYQNIAQLEKK
IEGLEAKKVAALKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNSLTDSLNRVIIRSPVDGIVNNLKYHTIGGVISHGQPIMEISPINDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQHPGQQQDNYYVARIEIDMDAFDKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPITDTAFKAFREK

Sequences:

>Translated_511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGHNSKRMTLINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVIIFLVLIGGLWSALAPLDSGAVAVGIVIPSTNKKTIQHNEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENVLGQYRNFLATENRLIAERDHLEQIEFSDFLMHDINLPEVAKIIHTQENLFRSRKEVYNSEKDALYQNIAQLEKK
IEGLEAKKVAALKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNSLTDSLNRVIIRSPVDGIVNNLKYHTIGGVISHGQPIMEISPINDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQHPGQQQDNYYVARIEIDMDAFDKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPITDTAFKAFREK
>Mature_511_residues
MQDLKHNKPQITPEQLKQLLSLREDALNLKGHNSKRMTLINTTLKKTSHAIEFLLVKLDRFVNFITKKTDKDRNNVAQAA
RSPILFGIYVIIFLVLIGGLWSALAPLDSGAVAVGIVIPSTNKKTIQHNEGGIINAIYVKQGDKVKEGDKLIELEETRIK
SEHENVLGQYRNFLATENRLIAERDHLEQIEFSDFLMHDINLPEVAKIIHTQENLFRSRKEVYNSEKDALYQNIAQLEKK
IEGLEAKKVAALKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEIAGIRHAITETQIKIINQQNK
YTERTLTELREAQVQTASLKEKYNSLTDSLNRVIIRSPVDGIVNNLKYHTIGGVISHGQPIMEISPINDPLIIEAKVSQK
NIDSVHEGLVAKIRFSAFKSRTTPTFTGKVVSISPDIVQDERQHPGQQQDNYYVARIEIDMDAFDKVAKVKNLELHPGMQ
AEVQIVTGTRTLLRYLLDPITDTAFKAFREK

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 57679; Mature: 57679

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLKHNKPQITPEQLKQLLSLREDALNLKGHNSKRMTLINTTLKKTSHAIEFLLVKLDR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
FVNFITKKTDKDRNNVAQAARSPILFGIYVIIFLVLIGGLWSALAPLDSGAVAVGIVIPS
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
TNKKTIQHNEGGIINAIYVKQGDKVKEGDKLIELEETRIKSEHENVLGQYRNFLATENRL
CCCCEEEECCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAERDHLEQIEFSDFLMHDINLPEVAKIIHTQENLFRSRKEVYNSEKDALYQNIAQLEKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IEGLEAKKVAALKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHCCCCCCHHHHHHH
AGIRHAITETQIKIINQQNKYTERTLTELREAQVQTASLKEKYNSLTDSLNRVIIRSPVD
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHH
GIVNNLKYHTIGGVISHGQPIMEISPINDPLIIEAKVSQKNIDSVHEGLVAKIRFSAFKS
HHHHCCCHHHHCCHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
RTTPTFTGKVVSISPDIVQDERQHPGQQQDNYYVARIEIDMDAFDKVAKVKNLELHPGMQ
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCC
AEVQIVTGTRTLLRYLLDPITDTAFKAFREK
EEEEEEECHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDLKHNKPQITPEQLKQLLSLREDALNLKGHNSKRMTLINTTLKKTSHAIEFLLVKLDR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
FVNFITKKTDKDRNNVAQAARSPILFGIYVIIFLVLIGGLWSALAPLDSGAVAVGIVIPS
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
TNKKTIQHNEGGIINAIYVKQGDKVKEGDKLIELEETRIKSEHENVLGQYRNFLATENRL
CCCCEEEECCCCEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCH
IAERDHLEQIEFSDFLMHDINLPEVAKIIHTQENLFRSRKEVYNSEKDALYQNIAQLEKK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
IEGLEAKKVAALKTAEVYQDRLKALRTLKEKGFVQKAALLDQEAKVAASKSDVATTEAEI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHHCCCCCCHHHHHHH
AGIRHAITETQIKIINQQNKYTERTLTELREAQVQTASLKEKYNSLTDSLNRVIIRSPVD
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHH
GIVNNLKYHTIGGVISHGQPIMEISPINDPLIIEAKVSQKNIDSVHEGLVAKIRFSAFKS
HHHHCCCHHHHCCHHHCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHC
RTTPTFTGKVVSISPDIVQDERQHPGQQQDNYYVARIEIDMDAFDKVAKVKNLELHPGMQ
CCCCCCCCEEEEECCHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCC
AEVQIVTGTRTLLRYLLDPITDTAFKAFREK
EEEEEEECHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]