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The map label for this gene is yhdG [H]

Identifier: 157825547

GI number: 157825547

Start: 418585

End: 419976

Strand: Direct

Name: yhdG [H]

Synonym: A1C_02290

Alternate gene names: 157825547

Gene position: 418585-419976 (Clockwise)

Preceding gene: 157825546

Following gene: 157825548

Centisome position: 34.0

GC content: 35.27

Gene sequence:

>1392_bases
ATGAGTTTTTTAAGGAAGAAAAGTTTTGAATCAGTAAAAGAGATAGGTAGCTCAAGCGGTCTTAGTAAGACGCTTGGAGC
ATTAGATTTAATATTACTAGGTCTTGGTGCAATGATTGGTACTGGCGTATTTGTCGTTACCGGTATAATTGCAGCTAAAT
ATTCAGGACCTGCGGTAATGTTATCTTATGCGATTGCAGGTATTACCTGTATCTTTGTAGCACTTGTTTATACTGAACTT
GCTGCAATGCTTCCAACTTCAGGAAGTATCTATACTTATTCCTATGTAGCATTCGGCGAAGTATTTGCTTGGATGATTGG
TAGTGTTATAATATTGGAGCTAGGTGTTGCTGCAGGAATAGTAGCTGCAGGCTGGTCTGGCTACGTACAAGGAATATTAG
CAGCAGGCGGAATCAATTTACCGAAAGAATTAACGACCGTACCGACAAACGGCGGTATAATAAATTTACCGGCATTTTTA
ATCTCGGTATTTATTGGATTTATTTTATATTTAGGGACTAAAGATAGTAAGCGACTGAATGCAATTTTAGTTTTCATAAA
AATGGTTGCAATATTTGTATTTATACTCGCTGCTGCTCCTCATTTCGATGTTACTAACTGGAGTAACTTTATGCCTTTCG
GCTTTAGTAATGTTCTAGTGGGTGCATCTATTTTATTTTTAGCTTTTACGGGATTTGGAACGATTGCAACTGCAGCTGAG
GAATGTAAAAATCCAAAACGTGATATAATGATCGGTATTATCGGCTCGCTTGTTCTAACTACTATAGTTTATGTAACAAT
GGCAGGGCTTGTTACCGGTATTGCACATTTTGATCAATTAAATAACGACCAACCGCTTGCTTATGCTTTAACTATCAATA
ATAGCAAGATTGGCTCTGCTATCGTGGCAACCGGTGCGGTTTGCGGTATGATGACGGTGTTGATGATGAATATTTACGGT
ACTTCTCGTATTTTTTATGCTATTGCACGTGACGGTTTACTACCGAAAAGTTTTGCAAAGCTGCACCCAAAATATGACAG
TCCGTATATTACAATTATAATATTTGCTTCTTTATCCGCTATCCTTGGAGGATTTTGTTCTACGGAATTATTAACGCAAT
TCACTTCAATGGGAGCATTAATTGATTATATAACAGTTACAATAATAGTAGTATTATTTAGAGTAAAGCTACCTGACGCT
CAAAGACCTTTTAAATGTCCTTTAGTATTTATTATTGTACCGTTTATTTTAATTGCTTGTGCATATTTACTATTTATTCA
AATATATGACGGTGAATTTAATATATTAATGGCAGGTCGTGCATTAATATATTGGTTTATTACGATATTTATTTTATATA
TTATAAGATCGTTTTTTATGACGAAGGAATGA

Upstream 100 bases:

>100_bases
GGATTACTAGAGATATAAGGTAGATTATACATTGTTGTATGGCGGATGTAATTCCAACTACGCTGGAATGATAGATCACT
CACTAAAACGGGAGAAACTA

Downstream 100 bases:

>100_bases
AGTTAGTATTTTTCAGTGTCATCACGCGACTTGATCGTGGGATCCAGTCTTTTTTAATTTTTTTTGGATACCGTGTTCAA
GCCACGGTATGACACCGAGC

Product: cationic amino acid transporter-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSFLRKKSFESVKEIGSSSGLSKTLGALDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYAIAGITCIFVALVYTEL
AAMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFL
ISVFIGFILYLGTKDSKRLNAILVFIKMVAIFVFILAAAPHFDVTNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAE
ECKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAHFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYG
TSRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLSAILGGFCSTELLTQFTSMGALIDYITVTIIVVLFRVKLPDA
QRPFKCPLVFIIVPFILIACAYLLFIQIYDGEFNILMAGRALIYWFITIFILYIIRSFFMTKE

Sequences:

>Translated_463_residues
MSFLRKKSFESVKEIGSSSGLSKTLGALDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYAIAGITCIFVALVYTEL
AAMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFL
ISVFIGFILYLGTKDSKRLNAILVFIKMVAIFVFILAAAPHFDVTNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAE
ECKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAHFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYG
TSRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLSAILGGFCSTELLTQFTSMGALIDYITVTIIVVLFRVKLPDA
QRPFKCPLVFIIVPFILIACAYLLFIQIYDGEFNILMAGRALIYWFITIFILYIIRSFFMTKE
>Mature_462_residues
SFLRKKSFESVKEIGSSSGLSKTLGALDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVMLSYAIAGITCIFVALVYTELA
AMLPTSGSIYTYSYVAFGEVFAWMIGSVIILELGVAAGIVAAGWSGYVQGILAAGGINLPKELTTVPTNGGIINLPAFLI
SVFIGFILYLGTKDSKRLNAILVFIKMVAIFVFILAAAPHFDVTNWSNFMPFGFSNVLVGASILFLAFTGFGTIATAAEE
CKNPKRDIMIGIIGSLVLTTIVYVTMAGLVTGIAHFDQLNNDQPLAYALTINNSKIGSAIVATGAVCGMMTVLMMNIYGT
SRIFYAIARDGLLPKSFAKLHPKYDSPYITIIIFASLSAILGGFCSTELLTQFTSMGALIDYITVTIIVVLFRVKLPDAQ
RPFKCPLVFIIVPFILIACAYLLFIQIYDGEFNILMAGRALIYWFITIFILYIIRSFFMTKE

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=33.2506203473945, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4507047, Length=426, Percent_Identity=29.3427230046948, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI181337167, Length=422, Percent_Identity=33.175355450237, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI258614005, Length=428, Percent_Identity=28.2710280373832, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI258614003, Length=427, Percent_Identity=28.5714285714286, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI114326544, Length=437, Percent_Identity=27.9176201372998, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI114326550, Length=437, Percent_Identity=27.9176201372998, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI258645169, Length=427, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI7657683, Length=387, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI186910308, Length=476, Percent_Identity=23.7394957983193, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910306, Length=476, Percent_Identity=23.7394957983193, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI186910304, Length=476, Percent_Identity=23.7394957983193, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI115648063, Length=468, Percent_Identity=23.9316239316239, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI115648022, Length=468, Percent_Identity=23.9316239316239, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI187423910, Length=430, Percent_Identity=24.1860465116279, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI7657591, Length=430, Percent_Identity=24.1860465116279, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082250, Length=362, Percent_Identity=25.1381215469613, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082023, Length=401, Percent_Identity=25.9351620947631, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788480, Length=423, Percent_Identity=25.0591016548463, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789017, Length=373, Percent_Identity=24.1286863270777, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786694, Length=453, Percent_Identity=24.7240618101545, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786302, Length=373, Percent_Identity=23.0563002680965, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=32.5301204819277, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17531343, Length=411, Percent_Identity=31.3868613138686, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI17533459, Length=417, Percent_Identity=30.2158273381295, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17540018, Length=438, Percent_Identity=25.5707762557078, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537453, Length=413, Percent_Identity=22.7602905569007, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17568033, Length=439, Percent_Identity=24.8291571753986, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=337, Percent_Identity=24.9258160237389, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=31.4903846153846, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=31.4903846153846, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI24667468, Length=383, Percent_Identity=32.8981723237598, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24668806, Length=427, Percent_Identity=31.615925058548, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI21356285, Length=427, Percent_Identity=31.615925058548, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668802, Length=427, Percent_Identity=31.615925058548, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI161077963, Length=407, Percent_Identity=31.6953316953317, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=30, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=30, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI116007818, Length=411, Percent_Identity=30.1703163017032, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI85725152, Length=411, Percent_Identity=30.1703163017032, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221331183, Length=428, Percent_Identity=27.1028037383178, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647653, Length=428, Percent_Identity=27.1028037383178, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664379, Length=428, Percent_Identity=27.1028037383178, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357367, Length=455, Percent_Identity=24.8351648351648, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550968, Length=453, Percent_Identity=24.2825607064018, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=453, Percent_Identity=24.2825607064018, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49878; Mature: 49747

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFLRKKSFESVKEIGSSSGLSKTLGALDLILLGLGAMIGTGVFVVTGIIAAKYSGPAVM
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH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HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]