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The map label for this gene is pyrH [H]

Identifier: 157825337

GI number: 157825337

Start: 211018

End: 211755

Strand: Reverse

Name: pyrH [H]

Synonym: A1C_01095

Alternate gene names: 157825337

Gene position: 211755-211018 (Counterclockwise)

Preceding gene: 157825338

Following gene: 157825336

Centisome position: 17.2

GC content: 36.86

Gene sequence:

>738_bases
ATGATATCAAATATAAATGCTCTAAAGTATAAAAAAGTTTTGCTTAAAGTTTCAGGGGAAGCTTTAATGGGGGATAAGCA
ATTTGGGCATGAATATGAGGTAATAAAAAAGATTTCCAGCGATATTAAGGAGGTCATTGATTTAGGAGTAGAAGTCGCTA
TCGTAGTCGGTGGCGGAAATATTTACCGTGGGATTAATGCAGCACTAGTAGGTATGGACCGAGCTTCAGCGGATTATATA
GGTATGCTTGCAACGGTGATTAATGCATTAACTTTACAGAACGTTATGGAAAGCCTAGATATCTATACAAGAGTTCTATC
GGCTATTCCTATGATGAGCGTGTGCGAACCTTATATTCGCCGTAAAGCTAAAAGACATATGGAAAAAAAGCGTGTAGTAA
TTTTTGCCGGTGGTACGGGTAACCCGTTTTGTACAACCGATAGTGCCGCAGTACTTCGTGCAATCGAAATGAATTGTGAT
ATGTTATTAAAAGCAACTCAGGTTGACGGTGTATATGATGCCGACCCTAAAAAAAATCCTGATGCTAAAAAATATTGCAC
TATTAACTATAAAGATGTTATAACTAATAACCTGCAAGTCATGGATACGGCAGCTATTGCAGTGGCAAGAGAGAATAAAT
TACCTATAAGAATATTTTCGATAAAAGAACAAGGAAATTTTGCTAGAGTAATACAAGATAAAGGCGAATATACGACAATT
GAGGAATCAGTAGTGTGA

Upstream 100 bases:

>100_bases
TAATAATATGTTATTAGTACATGCACTCAATAAATCATCGATTACCGACCTACAAAGAGATAGAATGATTAAAAAAATAC
AGAACAACTTGAAGTAGGAA

Downstream 100 bases:

>100_bases
ATTGTGGTATGATTTTTATGGTGTTGTTGCATGACTCGCTTTATGTTATTCCCGCGAAGGCGGGAATCCAGCATAAAGCG
AGCTTTTGATTTTAAAAACT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGNIYRGINAALVGMDRASADYI
GMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIRRKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCD
MLLKATQVDGVYDADPKKNPDAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTI
EESVV

Sequences:

>Translated_245_residues
MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGNIYRGINAALVGMDRASADYI
GMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIRRKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCD
MLLKATQVDGVYDADPKKNPDAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTI
EESVV
>Mature_245_residues
MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGNIYRGINAALVGMDRASADYI
GMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIRRKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCD
MLLKATQVDGVYDADPKKNPDAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTI
EESVV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=45.9227467811159, Blast_Score=231, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27033; Mature: 27033

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGN
CCCCCHHHHHHHHHHEECCCCEECCHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
IYRGINAALVGMDRASADYIGMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIR
CHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCDMLLKATQVDGVYDADPKKNP
HHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHEEEEECCCCEECCCCCCCC
DAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTI
CCCCEEEEEHHHHHCCCEEEEHHHHEEEEECCCCCEEEEEEECCCCEEEEHHCCCCEECH
EESVV
HHCCC
>Mature Secondary Structure
MISNINALKYKKVLLKVSGEALMGDKQFGHEYEVIKKISSDIKEVIDLGVEVAIVVGGGN
CCCCCHHHHHHHHHHEECCCCEECCHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
IYRGINAALVGMDRASADYIGMLATVINALTLQNVMESLDIYTRVLSAIPMMSVCEPYIR
CHHCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RKAKRHMEKKRVVIFAGGTGNPFCTTDSAAVLRAIEMNCDMLLKATQVDGVYDADPKKNP
HHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHEEEEECCCCEECCCCCCCC
DAKKYCTINYKDVITNNLQVMDTAAIAVARENKLPIRIFSIKEQGNFARVIQDKGEYTTI
CCCCEEEEEHHHHHCCCEEEEHHHHEEEEECCCCCEEEEEEECCCCEEEEHHCCCCEECH
EESVV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA