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The map label for this gene is frr [H]

Identifier: 157825336

GI number: 157825336

Start: 210244

End: 210804

Strand: Reverse

Name: frr [H]

Synonym: A1C_01090

Alternate gene names: 157825336

Gene position: 210804-210244 (Counterclockwise)

Preceding gene: 157825337

Following gene: 157825335

Centisome position: 17.12

GC content: 36.19

Gene sequence:

>561_bases
ATGGATACAGAAACGTTAAAGAAAATTTTACAAGAAAAAATGGATAAAGCTCTCAAAGTTTTGGATCATGAGCTTAAAGG
GCTACGTACCGGTAGAGCTTCAGTTAATTTGCTTGATAGCGTAACCGTGGAAGCTTACGGTAGTAAAATGCTGCTTTCAC
AAGTTGCTTCTCTATCCACCCCTGATGCACGAACAATTAACGTGCAGGTTTGGGACAAATCTATGGTATCCTCAGTAGAA
AAAGGGATTACTATAGCAAATCTTGGCTTAACTCCAGCAACAGACGGTCAATTAATCAGACTACCGATACCGGCTTTAAC
TGAAGAAAGACGTAAAGAACTGGTAAAGCTTGCTCATAAATACGGTGAGGATGCTAAAATTTCATTACGTAATATTAGAA
GAGATGGCAATGAAGAACTTAAAAAGCTAGAAAAGGATAATATTATTGCAAAAGATGAGCATCATAACTTATCTGAACAA
GTACAAAAGTTAACTGATGAATATAGCAGTAAAGTTGACTCGGCAATAAAACAAAAAGAACAAGACATAATGACTGTTTG
A

Upstream 100 bases:

>100_bases
TTTTTTAAGTACTGGATTCCCGCCTTTGCGGGAGTAACATTGTGGGTATTTCCAAATATACATCACAATGTCTCAATTAA
TAATATACGGATCAAATAAT

Downstream 100 bases:

>100_bases
TAATGTTACACATGTCATCCTGTGGTCAGGCGCACTAGGTGACAAAATTGATTTTACCGGTCCACGCAACAATGCTACGA
GAGAATGACATAAATTGGCT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDTETLKKILQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMLLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRKELVKLAHKYGEDAKISLRNIRRDGNEELKKLEKDNIIAKDEHHNLSEQ
VQKLTDEYSSKVDSAIKQKEQDIMTV

Sequences:

>Translated_186_residues
MDTETLKKILQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMLLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRKELVKLAHKYGEDAKISLRNIRRDGNEELKKLEKDNIIAKDEHHNLSEQ
VQKLTDEYSSKVDSAIKQKEQDIMTV
>Mature_186_residues
MDTETLKKILQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMLLSQVASLSTPDARTINVQVWDKSMVSSVE
KGITIANLGLTPATDGQLIRLPIPALTEERRKELVKLAHKYGEDAKISLRNIRRDGNEELKKLEKDNIIAKDEHHNLSEQ
VQKLTDEYSSKVDSAIKQKEQDIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=29.7142857142857, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI291042689, Length=147, Percent_Identity=31.9727891156463, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=41.8994413407821, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20876; Mature: 20876

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTETLKKILQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMLLSQVASLST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRKELVKLAHK
CCCEEEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
YGEDAKISLRNIRRDGNEELKKLEKDNIIAKDEHHNLSEQVQKLTDEYSSKVDSAIKQKE
HCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QDIMTV
HHHCCC
>Mature Secondary Structure
MDTETLKKILQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGSKMLLSQVASLST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDARTINVQVWDKSMVSSVEKGITIANLGLTPATDGQLIRLPIPALTEERRKELVKLAHK
CCCEEEEEEECCHHHHHHHHHCCEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHH
YGEDAKISLRNIRRDGNEELKKLEKDNIIAKDEHHNLSEQVQKLTDEYSSKVDSAIKQKE
HCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QDIMTV
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA