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The map label for this gene is gltS [H]

Identifier: 157373103

GI number: 157373103

Start: 5396371

End: 5397582

Strand: Reverse

Name: gltS [H]

Synonym: Spro_4872

Alternate gene names: 157373103

Gene position: 5397582-5396371 (Counterclockwise)

Preceding gene: 157373107

Following gene: 157373096

Centisome position: 99.06

GC content: 57.34

Gene sequence:

>1212_bases
ATGTTTCATCTTGATACTTATGGCACGTTAGTCGCGGCAACATTGGTTTTGCTCCTCGGGGGCAAATGTGTCACCAGCAT
TCCCCTGTTGAGAAAATACACTATCCCCGCCCCTGTCGCCGGTGGTTTGCTGGTGGCGCTCCTGTTGTTAGCCCTGAAAA
AGCTGGTTAACTGGGAAATCAGCTTCGATATGTCGCTAAAAGACCCGTTGATGCTGGCCTTCTTCGCCACCATCGGTCTG
AATGCCAACCTGGCGCGATTGCGTGCAGGCGGCAAGGCATTAATGGTGTTCCTGTTTGTGGTGCTGGGCCTGCTGCTGGT
GCAGAACGCCATCGGCATCGGCATGGCAAAAATGCTGGGTCTGGATCCGCTGATGGGTCTGATTGCCGGCTCCATCACCT
TGTCCGGTGGCCATGGCACCGGGGCGGCCTGGAGCAAGCTGTTTATTGAACGCTACGGGTTTGAAAACGCCACGGAAGTG
GCGATGGCCTGTGCCACCTTCGGGCTGGTTCTGGGTGGCCTGATCGGCGGCCCGGTTGCGCGTTATCTGGTGAAACACTC
GTCCACGCCGGAAGGCACGCCGGATGACAGCGTCCAGCCAAGCGGTTTTGAAAAGCCGGAGAGCGGTCGTTTGATCACCT
CGCTGGTCATGATTGAAACCATCGCCATGATCGCCATCTGTCTGAGTCTGGGGCAGCTTATCGCCGGCCTGTTGAATGGT
ACGGTGTTTGAACTGCCAAACTTCGTCTGCGTGCTGTTTGTTGGCGTGATCCTCAGCAACACCCTGGCCTTTACCGGCTT
TTATACCGTGTTTGAACGCGCGGTATCGGTGCTGGGGAACGTCAGCCTGTCGCTGTTCCTGGCCATGGCATTGATGAGCC
TGCGGCTATGGGAGTTGGCTTCGTTGGCGCTACCGATGTTGGCGATCCTGGCGGTGCAAACGCTGGTGATGGCGCTGTAC
GCGATTTTCGTCACCTACCGGGTGATGGGCAAAAACTACGATGCGGCGGTTCTGGCTGCTGGCCACTGTGGCTTCGGCAT
GGGCGCGACGCCAACGGCGATCGCCAATATGCAGGCGATTACCGATCGCTTCGGCCCATCGCACCTGGCGTTTCTGGTGG
TGCCGATGGTGGGGGCGTTCTTTATTGATATCGCCAACGCGATTGTGATTAAGCTGTATCTGCTGTTGCCGGTGTTCCCG
ACGATAGGTTGA

Upstream 100 bases:

>100_bases
TTTACTTCTAATCCCGCACTCATCAAGTTTTAAAAACTAAGCGGTTTTCTATAACTTATTATTTCTTAATTGGATCTTTC
CCCTTACATGGAGTACCTGG

Downstream 100 bases:

>100_bases
TTAGCAGATTGCAATAAACCAGAAGGGCGCCGATTGGCGCCCTTTGTTTTGGCAGGGAATTAGGCGTTTGAGTAACGCGC
TTTTTCCGGTAACCAGCGTT

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MFHLDTYGTLVAATLVLLLGGKCVTSIPLLRKYTIPAPVAGGLLVALLLLALKKLVNWEISFDMSLKDPLMLAFFATIGL
NANLARLRAGGKALMVFLFVVLGLLLVQNAIGIGMAKMLGLDPLMGLIAGSITLSGGHGTGAAWSKLFIERYGFENATEV
AMACATFGLVLGGLIGGPVARYLVKHSSTPEGTPDDSVQPSGFEKPESGRLITSLVMIETIAMIAICLSLGQLIAGLLNG
TVFELPNFVCVLFVGVILSNTLAFTGFYTVFERAVSVLGNVSLSLFLAMALMSLRLWELASLALPMLAILAVQTLVMALY
AIFVTYRVMGKNYDAAVLAAGHCGFGMGATPTAIANMQAITDRFGPSHLAFLVVPMVGAFFIDIANAIVIKLYLLLPVFP
TIG

Sequences:

>Translated_403_residues
MFHLDTYGTLVAATLVLLLGGKCVTSIPLLRKYTIPAPVAGGLLVALLLLALKKLVNWEISFDMSLKDPLMLAFFATIGL
NANLARLRAGGKALMVFLFVVLGLLLVQNAIGIGMAKMLGLDPLMGLIAGSITLSGGHGTGAAWSKLFIERYGFENATEV
AMACATFGLVLGGLIGGPVARYLVKHSSTPEGTPDDSVQPSGFEKPESGRLITSLVMIETIAMIAICLSLGQLIAGLLNG
TVFELPNFVCVLFVGVILSNTLAFTGFYTVFERAVSVLGNVSLSLFLAMALMSLRLWELASLALPMLAILAVQTLVMALY
AIFVTYRVMGKNYDAAVLAAGHCGFGMGATPTAIANMQAITDRFGPSHLAFLVVPMVGAFFIDIANAIVIKLYLLLPVFP
TIG
>Mature_403_residues
MFHLDTYGTLVAATLVLLLGGKCVTSIPLLRKYTIPAPVAGGLLVALLLLALKKLVNWEISFDMSLKDPLMLAFFATIGL
NANLARLRAGGKALMVFLFVVLGLLLVQNAIGIGMAKMLGLDPLMGLIAGSITLSGGHGTGAAWSKLFIERYGFENATEV
AMACATFGLVLGGLIGGPVARYLVKHSSTPEGTPDDSVQPSGFEKPESGRLITSLVMIETIAMIAICLSLGQLIAGLLNG
TVFELPNFVCVLFVGVILSNTLAFTGFYTVFERAVSVLGNVSLSLFLAMALMSLRLWELASLALPMLAILAVQTLVMALY
AIFVTYRVMGKNYDAAVLAAGHCGFGMGATPTAIANMQAITDRFGPSHLAFLVVPMVGAFFIDIANAIVIKLYLLLPVFP
TIG

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=399, Percent_Identity=81.203007518797, Blast_Score=586, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 42539; Mature: 42539

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHLDTYGTLVAATLVLLLGGKCVTSIPLLRKYTIPAPVAGGLLVALLLLALKKLVNWEI
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
SFDMSLKDPLMLAFFATIGLNANLARLRAGGKALMVFLFVVLGLLLVQNAIGIGMAKMLG
EECCCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDPLMGLIAGSITLSGGHGTGAAWSKLFIERYGFENATEVAMACATFGLVLGGLIGGPVA
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYLVKHSSTPEGTPDDSVQPSGFEKPESGRLITSLVMIETIAMIAICLSLGQLIAGLLNG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVFELPNFVCVLFVGVILSNTLAFTGFYTVFERAVSVLGNVSLSLFLAMALMSLRLWELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPMLAILAVQTLVMALYAIFVTYRVMGKNYDAAVLAAGHCGFGMGATPTAIANMQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
TDRFGPSHLAFLVVPMVGAFFIDIANAIVIKLYLLLPVFPTIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFHLDTYGTLVAATLVLLLGGKCVTSIPLLRKYTIPAPVAGGLLVALLLLALKKLVNWEI
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
SFDMSLKDPLMLAFFATIGLNANLARLRAGGKALMVFLFVVLGLLLVQNAIGIGMAKMLG
EECCCCCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LDPLMGLIAGSITLSGGHGTGAAWSKLFIERYGFENATEVAMACATFGLVLGGLIGGPVA
HHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYLVKHSSTPEGTPDDSVQPSGFEKPESGRLITSLVMIETIAMIAICLSLGQLIAGLLNG
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TVFELPNFVCVLFVGVILSNTLAFTGFYTVFERAVSVLGNVSLSLFLAMALMSLRLWELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALPMLAILAVQTLVMALYAIFVTYRVMGKNYDAAVLAAGHCGFGMGATPTAIANMQAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
TDRFGPSHLAFLVVPMVGAFFIDIANAIVIKLYLLLPVFPTIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2254324; 2017136; 7686882; 9278503; 1544582 [H]