| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is fabG [C]
Identifier: 157373090
GI number: 157373090
Start: 5379676
End: 5380566
Strand: Reverse
Name: fabG [C]
Synonym: Spro_4858
Alternate gene names: 157373090
Gene position: 5380566-5379676 (Counterclockwise)
Preceding gene: 157373091
Following gene: 157373089
Centisome position: 98.75
GC content: 52.08
Gene sequence:
>891_bases ATGAAACCCGACCTGCAGGATCGTGTTGCGATTATTACCGGAGCCGGAGGCGGGCTTGGCCGAGCACACGCACATCTGCT AGCCCGTTATGGTGCGAAAGTTGTGATCAATGATATCGGGCTGGGTGCCGACAAGGTTGCCGAAGAAATCAACTCATCAG GAGGGGATGCCATTAGTTTCCAAGCCTCTGTGACTGATGAAGAGAAAATAAAGGCCATGGTCACGGAAACTATAGAACGG TGGGGAAGGGTCGATATTCTGGTCAACAATGCAGGCAACCTGCGTGACAAGACTTTTGCCAAAATGACGTTAGATGATTT TCGCTCTGTGTTGGACGTACATCTAATGGGGGCAGTGATTTGCACCAAGGCCGTATGGGAGCATATGCATCGCCAAAAGT ATGGGCGCATCGTGTTCACGACGTCCTCTTCTGGTCTTTATGGCAATTTCGGGCAGGCCAATTATGCAGCGGCGAAAATG GGGCTGGTGGGGCTGATGCAAACACTGGCACTCGAAGGAGCCAAGAGTAACATTTTGGTGAATTGTTTGGCGCCTACTGC AGCGACCGCTATGAGCGATGGGCTTTTGATGCCGCAAGCAAAGCGTGTATTACAACCTGAAGCAGTGAGCCCGGCACTGT TGCCGCTGGTTTCGCAGTGTGCTCCTACCAGGGCTATTGTTTGCGCTGGTGCGGGTAATTTTGCGCGCGCCTACATAACG TTGACCGGTGGACGCTTTTTGGGCAACGACGCACATACCATCAATCGTATTTTCGCCGACTGGCAAGTGATCGGCGATCG CGAATCAGAGCAAGTTCCTGAGTCTGCCACTGCGCAGGTTCATCAAGAACTCATCGCTGCTTTCCGTTCAGAATCCGAAA ATAACCAGTGA
Upstream 100 bases:
>100_bases AATTGCCACTTAGCGCTACGGGAAAAGTACTGAAACGTGAACTGCGCGCGCTCTTTCTGACCGAACACCCTACCCCATTT GCATTATAAGGAACTGAATT
Downstream 100 bases:
>100_bases GAATCTACTATGCGTGATGCCGTTATTGTTTCTACAGCCCGAACTCCGATTGGCAAAGCCTATCGTGGCGCTTTCAATGC CACCCCATCTGCAACACTGG
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 296; Mature: 296
Protein sequence:
>296_residues MKPDLQDRVAIITGAGGGLGRAHAHLLARYGAKVVINDIGLGADKVAEEINSSGGDAISFQASVTDEEKIKAMVTETIER WGRVDILVNNAGNLRDKTFAKMTLDDFRSVLDVHLMGAVICTKAVWEHMHRQKYGRIVFTTSSSGLYGNFGQANYAAAKM GLVGLMQTLALEGAKSNILVNCLAPTAATAMSDGLLMPQAKRVLQPEAVSPALLPLVSQCAPTRAIVCAGAGNFARAYIT LTGGRFLGNDAHTINRIFADWQVIGDRESEQVPESATAQVHQELIAAFRSESENNQ
Sequences:
>Translated_296_residues MKPDLQDRVAIITGAGGGLGRAHAHLLARYGAKVVINDIGLGADKVAEEINSSGGDAISFQASVTDEEKIKAMVTETIER WGRVDILVNNAGNLRDKTFAKMTLDDFRSVLDVHLMGAVICTKAVWEHMHRQKYGRIVFTTSSSGLYGNFGQANYAAAKM GLVGLMQTLALEGAKSNILVNCLAPTAATAMSDGLLMPQAKRVLQPEAVSPALLPLVSQCAPTRAIVCAGAGNFARAYIT LTGGRFLGNDAHTINRIFADWQVIGDRESEQVPESATAQVHQELIAAFRSESENNQ >Mature_296_residues MKPDLQDRVAIITGAGGGLGRAHAHLLARYGAKVVINDIGLGADKVAEEINSSGGDAISFQASVTDEEKIKAMVTETIER WGRVDILVNNAGNLRDKTFAKMTLDDFRSVLDVHLMGAVICTKAVWEHMHRQKYGRIVFTTSSSGLYGNFGQANYAAAKM GLVGLMQTLALEGAKSNILVNCLAPTAATAMSDGLLMPQAKRVLQPEAVSPALLPLVSQCAPTRAIVCAGAGNFARAYIT LTGGRFLGNDAHTINRIFADWQVIGDRESEQVPESATAQVHQELIAAFRSESENNQ
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI4504505, Length=281, Percent_Identity=43.0604982206406, Blast_Score=217, Evalue=8e-57, Organism=Homo sapiens, GI40254992, Length=180, Percent_Identity=37.7777777777778, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758504, Length=190, Percent_Identity=34.2105263157895, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI15277342, Length=199, Percent_Identity=31.6582914572864, Blast_Score=82, Evalue=9e-16, Organism=Homo sapiens, GI10190704, Length=190, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI19923817, Length=240, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503817, Length=181, Percent_Identity=27.6243093922652, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI83715985, Length=175, Percent_Identity=34.2857142857143, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI7657478, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=3e-14, Organism=Homo sapiens, GI59889578, Length=156, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=28.7234042553192, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=29.5336787564767, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI31542939, Length=186, Percent_Identity=30.6451612903226, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=30.3664921465969, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=31.3609467455621, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40807363, Length=167, Percent_Identity=28.7425149700599, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI210032110, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=24.6073298429319, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=182, Percent_Identity=28.021978021978, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=28.9617486338798, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI5031737, Length=183, Percent_Identity=28.9617486338798, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=37.1584699453552, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=37.9120879120879, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=204, Percent_Identity=34.3137254901961, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1788459, Length=206, Percent_Identity=33.9805825242718, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1790717, Length=192, Percent_Identity=31.25, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI87082160, Length=181, Percent_Identity=31.4917127071823, Blast_Score=81, Evalue=9e-17, Organism=Escherichia coli, GI1789208, Length=182, Percent_Identity=29.6703296703297, Blast_Score=81, Evalue=1e-16, Organism=Escherichia coli, GI2367175, Length=184, Percent_Identity=33.695652173913, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1787526, Length=222, Percent_Identity=28.8288288288288, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1789378, Length=232, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=283, Percent_Identity=40.9893992932862, Blast_Score=199, Evalue=1e-51, Organism=Caenorhabditis elegans, GI25147288, Length=187, Percent_Identity=33.6898395721925, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17555706, Length=227, Percent_Identity=31.7180616740088, Blast_Score=90, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=30.8080808080808, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560332, Length=212, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=205, Percent_Identity=31.7073170731707, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203115, Length=223, Percent_Identity=28.2511210762332, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17538182, Length=191, Percent_Identity=35.6020942408377, Blast_Score=78, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=31.7708333333333, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI71994604, Length=181, Percent_Identity=30.3867403314917, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17564282, Length=172, Percent_Identity=29.0697674418605, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=32.0197044334975, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562908, Length=203, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193203117, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560676, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17560220, Length=248, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17531453, Length=196, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=186, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562904, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17544670, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193204405, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538480, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71994600, Length=184, Percent_Identity=28.804347826087, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17560150, Length=202, Percent_Identity=29.2079207920792, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=185, Percent_Identity=29.7297297297297, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17565030, Length=211, Percent_Identity=29.3838862559242, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=27.4111675126904, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=27.8947368421053, Blast_Score=65, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71997099, Length=200, Percent_Identity=31.5, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=292, Percent_Identity=44.1780821917808, Blast_Score=218, Evalue=6e-58, Organism=Saccharomyces cerevisiae, GI6324126, Length=196, Percent_Identity=30.1020408163265, Blast_Score=80, Evalue=5e-16, Organism=Drosophila melanogaster, GI18859837, Length=273, Percent_Identity=42.1245421245421, Blast_Score=206, Evalue=1e-53, Organism=Drosophila melanogaster, GI24639444, Length=185, Percent_Identity=36.7567567567568, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=34.0659340659341, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=31.0160427807487, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=31.2820512820513, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24581726, Length=213, Percent_Identity=29.5774647887324, Blast_Score=79, Evalue=5e-15, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI28571526, Length=185, Percent_Identity=29.1891891891892, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24644339, Length=184, Percent_Identity=29.3478260869565, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=25.6544502617801, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=28.6549707602339, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI281364892, Length=173, Percent_Identity=27.7456647398844, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21355319, Length=184, Percent_Identity=29.3478260869565, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=28.4210526315789, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007236, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI116007234, Length=214, Percent_Identity=28.9719626168224, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28571387, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=31.3829787234043, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 31667; Mature: 31667
Theoretical pI: Translated: 6.88; Mature: 6.88
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKPDLQDRVAIITGAGGGLGRAHAHLLARYGAKVVINDIGLGADKVAEEINSSGGDAISF CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEE QASVTDEEKIKAMVTETIERWGRVDILVNNAGNLRDKTFAKMTLDDFRSVLDVHLMGAVI EECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH CTKAVWEHMHRQKYGRIVFTTSSSGLYGNFGQANYAAAKMGLVGLMQTLALEGAKSNILV HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE NCLAPTAATAMSDGLLMPQAKRVLQPEAVSPALLPLVSQCAPTRAIVCAGAGNFARAYIT EEECCHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEE LTGGRFLGNDAHTINRIFADWQVIGDRESEQVPESATAQVHQELIAAFRSESENNQ EECCEEECCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MKPDLQDRVAIITGAGGGLGRAHAHLLARYGAKVVINDIGLGADKVAEEINSSGGDAISF CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCEEEE QASVTDEEKIKAMVTETIERWGRVDILVNNAGNLRDKTFAKMTLDDFRSVLDVHLMGAVI EECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH CTKAVWEHMHRQKYGRIVFTTSSSGLYGNFGQANYAAAKMGLVGLMQTLALEGAKSNILV HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE NCLAPTAATAMSDGLLMPQAKRVLQPEAVSPALLPLVSQCAPTRAIVCAGAGNFARAYIT EEECCHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEE LTGGRFLGNDAHTINRIFADWQVIGDRESEQVPESATAQVHQELIAAFRSESENNQ EECCEEECCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9634230 [H]