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The map label for this gene is gcd [H]

Identifier: 157373081

GI number: 157373081

Start: 5367158

End: 5369569

Strand: Reverse

Name: gcd [H]

Synonym: Spro_4849

Alternate gene names: 157373081

Gene position: 5369569-5367158 (Counterclockwise)

Preceding gene: 157373082

Following gene: 157373079

Centisome position: 98.54

GC content: 61.24

Gene sequence:

>2412_bases
ATGACAACCAGCAATACAAAGACCGGCGGCTCTTACCGCTGGGTCAGTGCCTTGCTGGGGCTTATCCTGCTACTCACCGG
CGTTGCCATGCTGTACGGCGGTATCCGCCTCATCACGCTGGATGGCTCCTGGTATTACGCGATCGCAGGCATCGTGTTGC
TGATAACGGCACCGTTATTGCTGCTGGCACGCCGCAGCGGCTTCGTGCTCTATGCCGGTTTTTGCGCAGCAACGTTGGCC
TGGGCTTTGTACGAATGCGGCTGGAACCCCATTGCGCTACTGCCGCGGGTGCTGTTCTTTCTGGTGTTACTCATCGTAAT
GTTGTTGACCTGGCGCTGGTTCGCCCGTCCATTTTTTGCGCGCCATAGCAAACGGGTGCGCGGCACCAGGCCGGCACTGC
TGGTCGGCAGCGCGTTGACGTTGTTACTCTTTAGCCTGTTCGTGGCCGGCTTGCAGCCTTTCCATGGCATCGATCTGGCT
GCGGCATTGGAGCAATATCCCGCCGAAAACACGCCAGTCGATTCGGCATTGACCGCCCCCGGCGATTGGCCGAACTACGG
CCGAACACCCGGTGGCCAGAGGTACTCGCCGCTGGAGCAAATCACTCCGGCCAACGTTGCCGATCTCACACTGGCCTGGA
GTTTCCACTCCGGTGCAACCGGCCTGCCCCAGGGCAATAAAGCGAGCGAGCTGATGTTCGAGGCAACGCCATTGAAGGTG
CGCGACAAACTCGTGTTCTGCACCCCACATGATGAAGTCATTGCAGTTTCGCCGGAGACAGGCAAATCGATTTGGCGCTT
CAACCCGCATGCGAATCTGAGAGCAGTACCCTTTCTTGCCTGCCGTGGCGTATCCTATGACGAAACGCCAATGGCCACCG
GCTTTTGCGCACATCGGATTATCACCGCCACGCTGGATGCCAAGATGTACGCGCTGGATGCCGATACCGGCCAGCGCTGC
CCGGCGTTCGGCCAGAACGGCGAAATCGACCTGACCGCAGGCATGGGCCTGGTCAAGCCGGGTTTCTACTACGTCACCTC
GCCGCCCTCGATCGTGCACGGCAAGGCGGTAATCGGTGGGTGGGTGTACGATAACGTGGAACGCGGCGAACCTTCCGGCG
TCGTGCGCGCATTCGATACCCGAAGCGGCAAACTGGCCTGGGCTTTCGACATGGGCCGCACCGATCGTACGACACTTCCA
CCCGAAGGCGAGTTCTACACGCGCGGCACGCCCAATGTATGGGCGCCGATCAGCACTGATCCGGTGTTGGGTTTGGTCTA
TCTGCCAACCGGTAACGAAACGCCGGATTTCTTCGGCGGCGGCAGGCAAGCCGTGTCGGAAAAATACGCCAGTTCGCTGA
TCGCTGTCGATGCGGATAGCGGAAAGATCCACTGGCACTTCCAGACCACTCACCACGACATCTGGGACTACGATGTCCCG
GCGCAACCGACTACGGTCGATTTACCTGGCGCACAGGGCAAGCCGCCGGTACTCGCCTTACTGGTACCGACCAAGCGCGG
CGAGTTGTTCATGCTCGACCGGCGCACGGGTGCCCCGCTGACTCACATCGAGGAGCGGCCGGTGCCGCAAGGGGCTGTGC
CAGGCGAACACCTGTCACCTACCCAGCCCTTCCAGACTGACATGCCGACGTTTGCACCAGCCACGTTGCGCGAAAGCGAC
ATGTGGGGAGCTACGCCGCTCGATCAGCTGTATTGCCGCATCCGCTTCAAGGAGTTGCGCTACGAGGGCCCGTTTACGCC
ACCATCGGTGCAAGGTTCACTGGCGTATCCCGGCTCGGCGGGTGTCTTCGAATGGGGTGGCGTGTCGGTCGACCCTTTGC
GTCATATCGTCGTGGCGAACAACAACTACATGGCGATCATCAACAAGCTGACACCGCGCGACCAGGTTTCAGCCAGCGGT
AAGCAAGGCAACAAAGGCGGTGACTTCGGCGGCCCGCAGCTGGGTACACCTTATGCCATCAGCGCCGCGCCGTTCCTATC
GCCATTGGCCATCCCTTGCAATCAGCCACCCTGGGGCATGCTCAGCGCGCTCGACCTGAAAACCCGCAAGCTCCTCTGGC
GCCATCCGCTGGGCAGCGCTTACGACAACGGCCCCTTCGGTATTTCCTCGCATGTGCCGCTGCAGGTGGGCGTGCCGAAC
ATGGGTGGCTCGGTGGTGACCCGCAGCGGCCTGATCTTTATCGCCGCCACCGCCGACCGCACGCTACGGGCGATTGATCT
GCGTACCGGCCGCGAGTTGTGGCACGACACACTGCCGTTTGGCGGTATTGCGACCCCCAGCGTCTACGAAGGCAAGGATG
GACGCCAATACATAGTCATTGCCGCAGGCGGCCATACCGGCCTTGGCAGTTCAGGCGGCGACGCGGTGATGGCGTTTGCA
TTGCCGAAATAA

Upstream 100 bases:

>100_bases
CAGGTGGTTTCCACGTCTTCATGGCTGTCACTTTCCTGCCGGAAGCGAAGGAGGTCTTTCGCCAAGTTAAAGCAGTGGCT
AAATACCTGGGGAATGCGTC

Downstream 100 bases:

>100_bases
CCTTGAAACAAGAGAATTCAAGGCATCGCACTGGAGCGCGGTCATTGCGTTATGAAACGCGTTCATATGATCCGCTCTCT
CTATTTCCTGGCTGATACCC

Product: Pyrrolo-quinoline quinone

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MTTSNTKTGGSYRWVSALLGLILLLTGVAMLYGGIRLITLDGSWYYAIAGIVLLITAPLLLLARRSGFVLYAGFCAATLA
WALYECGWNPIALLPRVLFFLVLLIVMLLTWRWFARPFFARHSKRVRGTRPALLVGSALTLLLFSLFVAGLQPFHGIDLA
AALEQYPAENTPVDSALTAPGDWPNYGRTPGGQRYSPLEQITPANVADLTLAWSFHSGATGLPQGNKASELMFEATPLKV
RDKLVFCTPHDEVIAVSPETGKSIWRFNPHANLRAVPFLACRGVSYDETPMATGFCAHRIITATLDAKMYALDADTGQRC
PAFGQNGEIDLTAGMGLVKPGFYYVTSPPSIVHGKAVIGGWVYDNVERGEPSGVVRAFDTRSGKLAWAFDMGRTDRTTLP
PEGEFYTRGTPNVWAPISTDPVLGLVYLPTGNETPDFFGGGRQAVSEKYASSLIAVDADSGKIHWHFQTTHHDIWDYDVP
AQPTTVDLPGAQGKPPVLALLVPTKRGELFMLDRRTGAPLTHIEERPVPQGAVPGEHLSPTQPFQTDMPTFAPATLRESD
MWGATPLDQLYCRIRFKELRYEGPFTPPSVQGSLAYPGSAGVFEWGGVSVDPLRHIVVANNNYMAIINKLTPRDQVSASG
KQGNKGGDFGGPQLGTPYAISAAPFLSPLAIPCNQPPWGMLSALDLKTRKLLWRHPLGSAYDNGPFGISSHVPLQVGVPN
MGGSVVTRSGLIFIAATADRTLRAIDLRTGRELWHDTLPFGGIATPSVYEGKDGRQYIVIAAGGHTGLGSSGGDAVMAFA
LPK

Sequences:

>Translated_803_residues
MTTSNTKTGGSYRWVSALLGLILLLTGVAMLYGGIRLITLDGSWYYAIAGIVLLITAPLLLLARRSGFVLYAGFCAATLA
WALYECGWNPIALLPRVLFFLVLLIVMLLTWRWFARPFFARHSKRVRGTRPALLVGSALTLLLFSLFVAGLQPFHGIDLA
AALEQYPAENTPVDSALTAPGDWPNYGRTPGGQRYSPLEQITPANVADLTLAWSFHSGATGLPQGNKASELMFEATPLKV
RDKLVFCTPHDEVIAVSPETGKSIWRFNPHANLRAVPFLACRGVSYDETPMATGFCAHRIITATLDAKMYALDADTGQRC
PAFGQNGEIDLTAGMGLVKPGFYYVTSPPSIVHGKAVIGGWVYDNVERGEPSGVVRAFDTRSGKLAWAFDMGRTDRTTLP
PEGEFYTRGTPNVWAPISTDPVLGLVYLPTGNETPDFFGGGRQAVSEKYASSLIAVDADSGKIHWHFQTTHHDIWDYDVP
AQPTTVDLPGAQGKPPVLALLVPTKRGELFMLDRRTGAPLTHIEERPVPQGAVPGEHLSPTQPFQTDMPTFAPATLRESD
MWGATPLDQLYCRIRFKELRYEGPFTPPSVQGSLAYPGSAGVFEWGGVSVDPLRHIVVANNNYMAIINKLTPRDQVSASG
KQGNKGGDFGGPQLGTPYAISAAPFLSPLAIPCNQPPWGMLSALDLKTRKLLWRHPLGSAYDNGPFGISSHVPLQVGVPN
MGGSVVTRSGLIFIAATADRTLRAIDLRTGRELWHDTLPFGGIATPSVYEGKDGRQYIVIAAGGHTGLGSSGGDAVMAFA
LPK
>Mature_802_residues
TTSNTKTGGSYRWVSALLGLILLLTGVAMLYGGIRLITLDGSWYYAIAGIVLLITAPLLLLARRSGFVLYAGFCAATLAW
ALYECGWNPIALLPRVLFFLVLLIVMLLTWRWFARPFFARHSKRVRGTRPALLVGSALTLLLFSLFVAGLQPFHGIDLAA
ALEQYPAENTPVDSALTAPGDWPNYGRTPGGQRYSPLEQITPANVADLTLAWSFHSGATGLPQGNKASELMFEATPLKVR
DKLVFCTPHDEVIAVSPETGKSIWRFNPHANLRAVPFLACRGVSYDETPMATGFCAHRIITATLDAKMYALDADTGQRCP
AFGQNGEIDLTAGMGLVKPGFYYVTSPPSIVHGKAVIGGWVYDNVERGEPSGVVRAFDTRSGKLAWAFDMGRTDRTTLPP
EGEFYTRGTPNVWAPISTDPVLGLVYLPTGNETPDFFGGGRQAVSEKYASSLIAVDADSGKIHWHFQTTHHDIWDYDVPA
QPTTVDLPGAQGKPPVLALLVPTKRGELFMLDRRTGAPLTHIEERPVPQGAVPGEHLSPTQPFQTDMPTFAPATLRESDM
WGATPLDQLYCRIRFKELRYEGPFTPPSVQGSLAYPGSAGVFEWGGVSVDPLRHIVVANNNYMAIINKLTPRDQVSASGK
QGNKGGDFGGPQLGTPYAISAAPFLSPLAIPCNQPPWGMLSALDLKTRKLLWRHPLGSAYDNGPFGISSHVPLQVGVPNM
GGSVVTRSGLIFIAATADRTLRAIDLRTGRELWHDTLPFGGIATPSVYEGKDGRQYIVIAAGGHTGLGSSGGDAVMAFAL
PK

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=819, Percent_Identity=41.1477411477411, Blast_Score=583, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 86724; Mature: 86593

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSNTKTGGSYRWVSALLGLILLLTGVAMLYGGIRLITLDGSWYYAIAGIVLLITAPLL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHH
LLARRSGFVLYAGFCAATLAWALYECGWNPIALLPRVLFFLVLLIVMLLTWRWFARPFFA
HHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHSKRVRGTRPALLVGSALTLLLFSLFVAGLQPFHGIDLAAALEQYPAENTPVDSALTAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GDWPNYGRTPGGQRYSPLEQITPANVADLTLAWSFHSGATGLPQGNKASELMFEATPLKV
CCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHEEEECCCCEE
RDKLVFCTPHDEVIAVSPETGKSIWRFNPHANLRAVPFLACRGVSYDETPMATGFCAHRI
ECEEEEECCCCCEEEECCCCCCCEEEECCCCCCEECCEEEECCCCCCCCCCHHHHHHHHE
ITATLDAKMYALDADTGQRCPAFGQNGEIDLTAGMGLVKPGFYYVTSPPSIVHGKAVIGG
EEEEECCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCEEECCEEEEC
WVYDNVERGEPSGVVRAFDTRSGKLAWAFDMGRTDRTTLPPEGEFYTRGTPNVWAPISTD
CEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCEECCCCCC
PVLGLVYLPTGNETPDFFGGGRQAVSEKYASSLIAVDADSGKIHWHFQTTHHDIWDYDVP
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCC
AQPTTVDLPGAQGKPPVLALLVPTKRGELFMLDRRTGAPLTHIEERPVPQGAVPGEHLSP
CCCCEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TQPFQTDMPTFAPATLRESDMWGATPLDQLYCRIRFKELRYEGPFTPPSVQGSLAYPGSA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEHCCCCCCCCCCCCCCEECCCCC
GVFEWGGVSVDPLRHIVVANNNYMAIINKLTPRDQVSASGKQGNKGGDFGGPQLGTPYAI
CCEECCCCCCCCEEEEEEECCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEE
SAAPFLSPLAIPCNQPPWGMLSALDLKTRKLLWRHPLGSAYDNGPFGISSHVPLQVGVPN
ECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
MGGSVVTRSGLIFIAATADRTLRAIDLRTGRELWHDTLPFGGIATPSVYEGKDGRQYIVI
CCCCEEEECCEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
AAGGHTGLGSSGGDAVMAFALPK
EECCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
TTSNTKTGGSYRWVSALLGLILLLTGVAMLYGGIRLITLDGSWYYAIAGIVLLITAPLL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHH
LLARRSGFVLYAGFCAATLAWALYECGWNPIALLPRVLFFLVLLIVMLLTWRWFARPFFA
HHHHCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHSKRVRGTRPALLVGSALTLLLFSLFVAGLQPFHGIDLAAALEQYPAENTPVDSALTAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GDWPNYGRTPGGQRYSPLEQITPANVADLTLAWSFHSGATGLPQGNKASELMFEATPLKV
CCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCCCCCCCHHHEEEECCCCEE
RDKLVFCTPHDEVIAVSPETGKSIWRFNPHANLRAVPFLACRGVSYDETPMATGFCAHRI
ECEEEEECCCCCEEEECCCCCCCEEEECCCCCCEECCEEEECCCCCCCCCCHHHHHHHHE
ITATLDAKMYALDADTGQRCPAFGQNGEIDLTAGMGLVKPGFYYVTSPPSIVHGKAVIGG
EEEEECCEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCEEECCEEEEC
WVYDNVERGEPSGVVRAFDTRSGKLAWAFDMGRTDRTTLPPEGEFYTRGTPNVWAPISTD
CEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCEECCCCCC
PVLGLVYLPTGNETPDFFGGGRQAVSEKYASSLIAVDADSGKIHWHFQTTHHDIWDYDVP
CEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCCCC
AQPTTVDLPGAQGKPPVLALLVPTKRGELFMLDRRTGAPLTHIEERPVPQGAVPGEHLSP
CCCCEEECCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
TQPFQTDMPTFAPATLRESDMWGATPLDQLYCRIRFKELRYEGPFTPPSVQGSLAYPGSA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEHCCCCCCCCCCCCCCEECCCCC
GVFEWGGVSVDPLRHIVVANNNYMAIINKLTPRDQVSASGKQGNKGGDFGGPQLGTPYAI
CCEECCCCCCCCEEEEEEECCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEE
SAAPFLSPLAIPCNQPPWGMLSALDLKTRKLLWRHPLGSAYDNGPFGISSHVPLQVGVPN
ECCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
MGGSVVTRSGLIFIAATADRTLRAIDLRTGRELWHDTLPFGGIATPSVYEGKDGRQYIVI
CCCCEEEECCEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
AAGGHTGLGSSGGDAVMAFALPK
EECCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]