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The map label for this gene is fieF

Identifier: 157373040

GI number: 157373040

Start: 5327379

End: 5328281

Strand: Reverse

Name: fieF

Synonym: Spro_4808

Alternate gene names: 157373040

Gene position: 5328281-5327379 (Counterclockwise)

Preceding gene: 157373041

Following gene: 157373039

Centisome position: 97.79

GC content: 57.25

Gene sequence:

>903_bases
ATGGAACCGCAATATGCGCGTTTGGTGAAATCTGCCGCGTTAGCTGCCACTGCGTTGGCCTCGATACTGCTACTGATCAA
AATTGTCGCCTGGTACCACACCGGTTCGGTGAGCCTGCTGGCCGCTTTGGTAGATTCCCTGGTGGATATCGCCGCGTCGC
TGACCAACTTGCTGGTGGTGCGTTATTCGCTGCAGCCGGCCGACGAGGAACACACCTTCGGGCATGGTAAGGCCGAGTCG
TTGGCCGCGCTGGCGCAGAGCATGTTTATTTCCGGCTCGGCACTGTTTCTGTTCCTGACCGGCTTCCAGCATCTGTACTC
TCCGGAAACGCTGCGCGATCCCGGTGTTGGTATTGCCGTGACGGTGGTGGCGTTGTTCAGCACCTTGCTGCTGGTCACCT
ATCAGCGTTGGGTAGTAAGGAAAACCCGTAGTCAGGCCGTACGAGCAGATATGCTGCATTATCAGTCAGATGTCATGATG
AATGGTGCTATTCTTATAGCGCTTGCGCTAAGCTGGTACGGTTTTCAACGGGCGGATGCGCTGTTTGCATTGGCCATTGG
CGTCTACATTCTTTATAGCGCGCTGCGGATGGGCCATGAGGCGGTGCAATCGCTGCTGGACAGGGCATTGCCGGACGATG
AGCGTCAGGCAATTATTGATGTGATTTCTTCCTGGCCAGGGGTGAAAGGTGCGCATGACCTGCGGACCCGCCAGTCCGGT
CCGACGCGTTTTATCCAGTTGCATCTGGAAATGGACGATGCGCTGCCGCTGATGCAGGCGCATCTTCTGGCCGAGCAGGT
GGAACAGGCACTGTTGCATCGTTTCCCCGGAGCGGATGTCCTCATTCACCAGGATCCCTGTTCCGTGGTGCCAGAGGGCC
GACAGGGGCGTTGGGAGCTATAA

Upstream 100 bases:

>100_bases
CCATAGACACCATCCCTGTCTTCCCCCGCCATGATGGCGGGGTTTTTTTTGTCCATCATTCCGCTATATTGGCCCTCTCA
ACGTTTAACCTGGATGGGTT

Downstream 100 bases:

>100_bases
TCAATACAGGGCCTGTAAGATCGGTGCAACGGGTGAATGGCGGAGTTAGCTCAGCGTGCCATGATGGTTTTTTACCGCAA
TATTGCGTGACTTGAATCAA

Product: ferrous iron efflux protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MEPQYARLVKSAALAATALASILLLIKIVAWYHTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADEEHTFGHGKAES
LAALAQSMFISGSALFLFLTGFQHLYSPETLRDPGVGIAVTVVALFSTLLLVTYQRWVVRKTRSQAVRADMLHYQSDVMM
NGAILIALALSWYGFQRADALFALAIGVYILYSALRMGHEAVQSLLDRALPDDERQAIIDVISSWPGVKGAHDLRTRQSG
PTRFIQLHLEMDDALPLMQAHLLAEQVEQALLHRFPGADVLIHQDPCSVVPEGRQGRWEL

Sequences:

>Translated_300_residues
MEPQYARLVKSAALAATALASILLLIKIVAWYHTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADEEHTFGHGKAES
LAALAQSMFISGSALFLFLTGFQHLYSPETLRDPGVGIAVTVVALFSTLLLVTYQRWVVRKTRSQAVRADMLHYQSDVMM
NGAILIALALSWYGFQRADALFALAIGVYILYSALRMGHEAVQSLLDRALPDDERQAIIDVISSWPGVKGAHDLRTRQSG
PTRFIQLHLEMDDALPLMQAHLLAEQVEQALLHRFPGADVLIHQDPCSVVPEGRQGRWEL
>Mature_300_residues
MEPQYARLVKSAALAATALASILLLIKIVAWYHTGSVSLLAALVDSLVDIAASLTNLLVVRYSLQPADEEHTFGHGKAES
LAALAQSMFISGSALFLFLTGFQHLYSPETLRDPGVGIAVTVVALFSTLLLVTYQRWVVRKTRSQAVRADMLHYQSDVMM
NGAILIALALSWYGFQRADALFALAIGVYILYSALRMGHEAVQSLLDRALPDDERQAIIDVISSWPGVKGAHDLRTRQSG
PTRFIQLHLEMDDALPLMQAHLLAEQVEQALLHRFPGADVLIHQDPCSVVPEGRQGRWEL

Specific function: Cation-efflux transporter that may have a role in detoxification

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily

Homologues:

Organism=Escherichia coli, GI1790349, Length=297, Percent_Identity=79.1245791245791, Blast_Score=476, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIEF_SERP5 (A8GLB1)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001481029.1
- ProteinModelPortal:   A8GLB1
- SMR:   A8GLB1
- STRING:   A8GLB1
- GeneID:   5605582
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4808
- eggNOG:   COG0053
- HOGENOM:   HBG317426
- OMA:   INFIAIR
- ProtClustDB:   PRK09509
- BioCyc:   SPRO399741:SPRO_4808-MONOMER
- HAMAP:   MF_01425
- InterPro:   IPR002524
- PANTHER:   PTHR11562
- TIGRFAMs:   TIGR01297

Pfam domain/function: PF01545 Cation_efflux

EC number: NA

Molecular weight: Translated: 32979; Mature: 32979

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1227cbd0)-; HASH(0x1260db68)-; HASH(0x121c35e4)-; HASH(0x10ac1298)-; HASH(0x122d7440)-; HASH(0x123dc960)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPQYARLVKSAALAATALASILLLIKIVAWYHTGSVSLLAALVDSLVDIAASLTNLLVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RYSLQPADEEHTFGHGKAESLAALAQSMFISGSALFLFLTGFQHLYSPETLRDPGVGIAV
HEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
TVVALFSTLLLVTYQRWVVRKTRSQAVRADMLHYQSDVMMNGAILIALALSWYGFQRADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LFALAIGVYILYSALRMGHEAVQSLLDRALPDDERQAIIDVISSWPGVKGAHDLRTRQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCC
PTRFIQLHLEMDDALPLMQAHLLAEQVEQALLHRFPGADVLIHQDPCSVVPEGRQGRWEL
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MEPQYARLVKSAALAATALASILLLIKIVAWYHTGSVSLLAALVDSLVDIAASLTNLLVV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RYSLQPADEEHTFGHGKAESLAALAQSMFISGSALFLFLTGFQHLYSPETLRDPGVGIAV
HEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
TVVALFSTLLLVTYQRWVVRKTRSQAVRADMLHYQSDVMMNGAILIALALSWYGFQRADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LFALAIGVYILYSALRMGHEAVQSLLDRALPDDERQAIIDVISSWPGVKGAHDLRTRQSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCC
PTRFIQLHLEMDDALPLMQAHLLAEQVEQALLHRFPGADVLIHQDPCSVVPEGRQGRWEL
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA