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The map label for this gene is argE [H]

Identifier: 157373014

GI number: 157373014

Start: 5297484

End: 5298629

Strand: Direct

Name: argE [H]

Synonym: Spro_4782

Alternate gene names: 157373014

Gene position: 5297484-5298629 (Clockwise)

Preceding gene: 157373009

Following gene: 157373015

Centisome position: 97.22

GC content: 59.51

Gene sequence:

>1146_bases
ATGAAATTACCTCCATTTATTGAGCTGTACCGGGCGTTGATCGCCACTCCGTCGATCAGCGCCACCGATGGCGCCCTCGA
TCAGAGTAATGAAGCGTTAATCAACTTGCTGGCCGGCTGGTTTGCCGATTTGGGCTTTCGCGTCGACGTGCAGCCGGTGC
CGGACAGCCGCAACAAATTCAACCTGCTGGCCAGCATTGGCGAAGGCAGCGGTGGCCTGCTGCTGGCGGGTCACACCGAC
ACCGTGCCTTATGATGAAGGCCGCTGGACGCGCGACCCTTTCACCCTGACCGAACACGACAATAAGCTGTACGGTCTGGG
CACCGCCGATATGAAAGGCTTCTTTGCCTTTATTCTGGATGCGGTACGCGACATCGACGCCAGCCAACTGACCAATCCTT
TATACATTCTGGCCACCGCAGATGAAGAAACGACGATGGCCGGCGCACGTTATTTTGCCGCCTCGACCAGCATCCGTCCG
GACTTCGCCATTATCGGTGAGCCAACCTCGCTGCAGCCGGTACGCGCGCACAAGGGCCACATAGCCAACGCCATCCGCAT
CGTCGGCCAATCCGGCCACTCGAGTGACCCGGCGCGCGGCGTGAACGCCATCGATTTGATGCATGAAACCATCGGCCGCC
TGATGGAACTGCGCAAAACGTTGCAAGAGCGCTTTAACAACCCGGCCTTTGCCGTGCCCTACCCGACCATGAACTTCGGT
CATATCAACGGGGGCGATGCGGCCAACCGTATCTGCGCCTGCTGCGAGCTGCATCTGGATATCCGCCCGTTACCGGGCAT
GACGCTCGACAACATCAACGAACTGATGCAGCAAACGCTGGAGCCAGTCAGCCAGCGCTGGCCGGGCCGCCTGAGTATTG
AGGAGCTGCACGCCTCGGTACCGGGCTATGAGTGCCCGACCGATCACCATATGGTGGCGGTGATTGAGAAACTGCTGGGC
ACCCGCACGCAGGTGGTCAACTATTGCACTGAGGCTCCCTTCGTCCAGCAGGTCTGCCCGACGCTGGTGTTGGGCCCTGG
CTCTATCGACCAGGCGCATCAACCGGACGAATACATAGATACCGGCTTTATCGAACCGACGCGCAAGCTGCTGGGTCAGT
TGGTCAGCCACTTCTGCCGCCAATAA

Upstream 100 bases:

>100_bases
CGGGAATCGGGTTCCCTTACGCTCCAGCTTATTGTATTTTTATTCACAATAAATGCATGAATATTGATACCAACCTAACC
AAAGGCTGTCAACAGTGAAG

Downstream 100 bases:

>100_bases
ACCTGACACAGGGTAGGGTTAATGATTTATCATCTCCCTACCCATTAATAAGTAGCAAACCAAGGAAATAAGCCAGACTG
ATAACCGGCGCAGCGTAATT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKLPPFIELYRALIATPSISATDGALDQSNEALINLLAGWFADLGFRVDVQPVPDSRNKFNLLASIGEGSGGLLLAGHTD
TVPYDEGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDAVRDIDASQLTNPLYILATADEETTMAGARYFAASTSIRP
DFAIIGEPTSLQPVRAHKGHIANAIRIVGQSGHSSDPARGVNAIDLMHETIGRLMELRKTLQERFNNPAFAVPYPTMNFG
HINGGDAANRICACCELHLDIRPLPGMTLDNINELMQQTLEPVSQRWPGRLSIEELHASVPGYECPTDHHMVAVIEKLLG
TRTQVVNYCTEAPFVQQVCPTLVLGPGSIDQAHQPDEYIDTGFIEPTRKLLGQLVSHFCRQ

Sequences:

>Translated_381_residues
MKLPPFIELYRALIATPSISATDGALDQSNEALINLLAGWFADLGFRVDVQPVPDSRNKFNLLASIGEGSGGLLLAGHTD
TVPYDEGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDAVRDIDASQLTNPLYILATADEETTMAGARYFAASTSIRP
DFAIIGEPTSLQPVRAHKGHIANAIRIVGQSGHSSDPARGVNAIDLMHETIGRLMELRKTLQERFNNPAFAVPYPTMNFG
HINGGDAANRICACCELHLDIRPLPGMTLDNINELMQQTLEPVSQRWPGRLSIEELHASVPGYECPTDHHMVAVIEKLLG
TRTQVVNYCTEAPFVQQVCPTLVLGPGSIDQAHQPDEYIDTGFIEPTRKLLGQLVSHFCRQ
>Mature_381_residues
MKLPPFIELYRALIATPSISATDGALDQSNEALINLLAGWFADLGFRVDVQPVPDSRNKFNLLASIGEGSGGLLLAGHTD
TVPYDEGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILDAVRDIDASQLTNPLYILATADEETTMAGARYFAASTSIRP
DFAIIGEPTSLQPVRAHKGHIANAIRIVGQSGHSSDPARGVNAIDLMHETIGRLMELRKTLQERFNNPAFAVPYPTMNFG
HINGGDAANRICACCELHLDIRPLPGMTLDNINELMQQTLEPVSQRWPGRLSIEELHASVPGYECPTDHHMVAVIEKLLG
TRTQVVNYCTEAPFVQQVCPTLVLGPGSIDQAHQPDEYIDTGFIEPTRKLLGQLVSHFCRQ

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=75.6613756613757, Blast_Score=627, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=373, Percent_Identity=26.2734584450402, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788816, Length=259, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=388, Percent_Identity=26.0309278350515, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41829; Mature: 41829

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPPFIELYRALIATPSISATDGALDQSNEALINLLAGWFADLGFRVDVQPVPDSRNKF
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
NLLASIGEGSGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILD
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHH
AVRDIDASQLTNPLYILATADEETTMAGARYFAASTSIRPDFAIIGEPTSLQPVRAHKGH
HHHCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHCCH
IANAIRIVGQSGHSSDPARGVNAIDLMHETIGRLMELRKTLQERFNNPAFAVPYPTMNFG
HHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
HINGGDAANRICACCELHLDIRPLPGMTLDNINELMQQTLEPVSQRWPGRLSIEELHASV
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PGYECPTDHHMVAVIEKLLGTRTQVVNYCTEAPFVQQVCPTLVLGPGSIDQAHQPDEYID
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCHHEEECCCCCCCCCCCHHHHH
TGFIEPTRKLLGQLVSHFCRQ
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLPPFIELYRALIATPSISATDGALDQSNEALINLLAGWFADLGFRVDVQPVPDSRNKF
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCE
NLLASIGEGSGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDNKLYGLGTADMKGFFAFILD
EEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHH
AVRDIDASQLTNPLYILATADEETTMAGARYFAASTSIRPDFAIIGEPTSLQPVRAHKGH
HHHCCCHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHCCH
IANAIRIVGQSGHSSDPARGVNAIDLMHETIGRLMELRKTLQERFNNPAFAVPYPTMNFG
HHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
HINGGDAANRICACCELHLDIRPLPGMTLDNINELMQQTLEPVSQRWPGRLSIEELHASV
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PGYECPTDHHMVAVIEKLLGTRTQVVNYCTEAPFVQQVCPTLVLGPGSIDQAHQPDEYID
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCHHEEECCCCCCCCCCCHHHHH
TGFIEPTRKLLGQLVSHFCRQ
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA