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The map label for this gene is glpD [H]

Identifier: 157372874

GI number: 157372874

Start: 5123795

End: 5125303

Strand: Direct

Name: glpD [H]

Synonym: Spro_4642

Alternate gene names: 157372874

Gene position: 5123795-5125303 (Clockwise)

Preceding gene: 157372872

Following gene: 157372881

Centisome position: 94.03

GC content: 57.52

Gene sequence:

>1509_bases
GTGGAAACCAAAGACTTGATCGTTATCGGTGGCGGCATCAACGGTGCCGGCATCGCGGCCGATGCTGCCGGGCGCGGGCT
GTCCGTTCTGCTACTGGAAGCGCAAGACTTGGCCTGTGCTACGTCTTCCGCCAGTTCCAAACTGATCCACGGCGGCCTGC
GCTACCTGGAACACTACGAATTCCGGTTGGTGAGCGAAGCGCTGGCCGAGCGTGAAGTGTTACTGCGACTGGCACCACAC
ATCGCCTTCCCAATGCGTTTCCGTCTGCCGCATCAGCCGCACCTGCGCCCGGCCTGGATGATCCGTATCGGTCTGTTCCT
TTACGATCACCTGGGGAAACGCACCAGTCTGCCAGGCAGCAAGGGTTTGCGCTTTGGACCAGAATCGGTGCTGAAGCCTG
AATTGAAGCGCGGTTTCGAATATTCTGACTGCTGGGTCGACGATGCTCGCCTGGTGGTACTCAATGCCCAGGAAGTGGAA
AAGCGCGGTGGCGAAGTGCGCACACGCACCAAAGTGACCCGTGCATGGCGTGAAAACGGCCTGTGGATGGTGGAAGCGGT
CGACGTCGACAGTGGCAAAACCTTTACCTGGCGCGCCAAGGGCCTGGTGAACGCCACCGGTCCATGGGTGAAACACTTCT
TCGACGATGGTCTGAAGCTGAAATCCCCTTATGGCATCCGTTTGATCAAAGGCAGCCACATCGTGGTACCGCGTGTACAC
GATCAGCCACAGTCCTATATTCTGCAAAACGAAGACCATCGTATCGTCTTCGTGATCCCATGGAATGACGAATTCTCGAT
CATCGGCACCACCGACGTGGAGTATCACGGCGATCCGAAAGATGTGAAGATCGACGATAACGAAATCAACTATCTGCTGA
AAGTGTATAACGACCACTTCAAGAAGCAGTTGGGCCGTGACGATATCGTCTGGACATACTCTGGCGTGCGTCCGCTGTGT
GACGACGAGTCCGATTCACCGCAGGCGGTGACCCGTGATTACACGCTGGACGTACATGACGAGCAGGGTAAAGCGCCGTT
GCTTTCCGTATTCGGCGGCAAACTGACGACCTACCGCAAGCTGGCTGAGCATGCGATGGAAAAACTGGCGCACTACTACC
CTGGTTGTGGCCCGGCGTGGACCAAAAACGGTTCGCTGCCAGGTGGTGACATCGGTGGCGATCGCGACAGCTACGCCGCA
AAACTGCGCCGTGAACACAGCTGGTTGCCGGAATCCCTGGCACGCCGCTTTGCACGCACCTACGGCAGCCACAGCGAGCT
GATCCTGGCCAATGCCAATAGCCTCAGCGACCTGGGTGAAGATTTCGGTCATGGCCTGCATGAAGCCGAATTGCGCTACC
TGATCGACAAAGAATGGGTGGTGGAACTCGATGACGCTATCTGGCGCCGTACCAAGCTGGGTATGTGGCTGGACGAAGCG
CAGCAGGCGCGGGTAAAAGCCTGGCTGGCAGAACACGTGAAAGCGAAAACCCTGTCTCTGGCATCGTAA

Upstream 100 bases:

>100_bases
TTTGTTTGGTTAAGTCTTGGCTTGTTTGTTGGTTTTTGATTACAATCATGAGCGAAAACGAACATGAAAGAGCTATTTCG
AACATCTGGAGGAAGTTGAC

Downstream 100 bases:

>100_bases
CTCGCCAAAGCTAAAAAGGGCCGGATTTCCGGCCCTTTTGTATTTACAGCTTGATAGGCTTGATGTGCCAGATCTCGTCC
GCATACTCCTGAATGGTGCG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLRLAPH
IAFPMRFRLPHQPHLRPAWMIRIGLFLYDHLGKRTSLPGSKGLRFGPESVLKPELKRGFEYSDCWVDDARLVVLNAQEVE
KRGGEVRTRTKVTRAWRENGLWMVEAVDVDSGKTFTWRAKGLVNATGPWVKHFFDDGLKLKSPYGIRLIKGSHIVVPRVH
DQPQSYILQNEDHRIVFVIPWNDEFSIIGTTDVEYHGDPKDVKIDDNEINYLLKVYNDHFKKQLGRDDIVWTYSGVRPLC
DDESDSPQAVTRDYTLDVHDEQGKAPLLSVFGGKLTTYRKLAEHAMEKLAHYYPGCGPAWTKNGSLPGGDIGGDRDSYAA
KLRREHSWLPESLARRFARTYGSHSELILANANSLSDLGEDFGHGLHEAELRYLIDKEWVVELDDAIWRRTKLGMWLDEA
QQARVKAWLAEHVKAKTLSLAS

Sequences:

>Translated_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLRLAPH
IAFPMRFRLPHQPHLRPAWMIRIGLFLYDHLGKRTSLPGSKGLRFGPESVLKPELKRGFEYSDCWVDDARLVVLNAQEVE
KRGGEVRTRTKVTRAWRENGLWMVEAVDVDSGKTFTWRAKGLVNATGPWVKHFFDDGLKLKSPYGIRLIKGSHIVVPRVH
DQPQSYILQNEDHRIVFVIPWNDEFSIIGTTDVEYHGDPKDVKIDDNEINYLLKVYNDHFKKQLGRDDIVWTYSGVRPLC
DDESDSPQAVTRDYTLDVHDEQGKAPLLSVFGGKLTTYRKLAEHAMEKLAHYYPGCGPAWTKNGSLPGGDIGGDRDSYAA
KLRREHSWLPESLARRFARTYGSHSELILANANSLSDLGEDFGHGLHEAELRYLIDKEWVVELDDAIWRRTKLGMWLDEA
QQARVKAWLAEHVKAKTLSLAS
>Mature_502_residues
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLRLAPH
IAFPMRFRLPHQPHLRPAWMIRIGLFLYDHLGKRTSLPGSKGLRFGPESVLKPELKRGFEYSDCWVDDARLVVLNAQEVE
KRGGEVRTRTKVTRAWRENGLWMVEAVDVDSGKTFTWRAKGLVNATGPWVKHFFDDGLKLKSPYGIRLIKGSHIVVPRVH
DQPQSYILQNEDHRIVFVIPWNDEFSIIGTTDVEYHGDPKDVKIDDNEINYLLKVYNDHFKKQLGRDDIVWTYSGVRPLC
DDESDSPQAVTRDYTLDVHDEQGKAPLLSVFGGKLTTYRKLAEHAMEKLAHYYPGCGPAWTKNGSLPGGDIGGDRDSYAA
KLRREHSWLPESLARRFARTYGSHSELILANANSLSDLGEDFGHGLHEAELRYLIDKEWVVELDDAIWRRTKLGMWLDEA
QQARVKAWLAEHVKAKTLSLAS

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=518, Percent_Identity=30.8880308880309, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI285002231, Length=518, Percent_Identity=30.8880308880309, Blast_Score=171, Evalue=2e-42,
Organism=Escherichia coli, GI2367226, Length=502, Percent_Identity=80.4780876494024, Blast_Score=799, Evalue=0.0,
Organism=Escherichia coli, GI1788574, Length=491, Percent_Identity=25.8655804480652, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=539, Percent_Identity=29.4990723562152, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17509253, Length=517, Percent_Identity=29.4003868471954, Blast_Score=147, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6322036, Length=534, Percent_Identity=26.5917602996255, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI161077125, Length=521, Percent_Identity=30.1343570057582, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24653942, Length=521, Percent_Identity=30.1343570057582, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24653944, Length=521, Percent_Identity=30.1343570057582, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI20130025, Length=521, Percent_Identity=30.1343570057582, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586295, Length=516, Percent_Identity=26.5503875968992, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19921278, Length=505, Percent_Identity=24.950495049505, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56636; Mature: 56636

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCCHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLRLAPHIAFPMRFRLPHQPHLRPAWMIRIGLFLYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KGLRFGPESVLKPELKRGFEYSDCWVDDARLVVLNAQEVEKRGGEVRTRTKVTRAWRENG
CCCCCCCHHHCCHHHHCCCCCCCEEECCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHCC
LWMVEAVDVDSGKTFTWRAKGLVNATGPWVKHFFDDGLKLKSPYGIRLIKGSHIVVPRVH
EEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCEECCCCCEEEEECCEEEEECCC
DQPQSYILQNEDHRIVFVIPWNDEFSIIGTTDVEYHGDPKDVKIDDNEINYLLKVYNDHF
CCCHHHHEECCCCEEEEEEECCCCEEEEECCCCEECCCCCCEEECCHHHHHHHHHHHHHH
KKQLGRDDIVWTYSGVRPLCDDESDSPQAVTRDYTLDVHDEQGKAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHCCCHHHHHH
LAEHAMEKLAHYYPGCGPAWTKNGSLPGGDIGGDRDSYAAKLRREHSWLPESLARRFART
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
YGSHSELILANANSLSDLGEDFGHGLHEAELRYLIDKEWVVELDDAIWRRTKLGMWLDEA
HCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHH
QQARVKAWLAEHVKAKTLSLAS
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYE
CCCCCEEEECCCCCCCCEECCCCCCCEEEEEEECCCHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLRLAPHIAFPMRFRLPHQPHLRPAWMIRIGLFLYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
KGLRFGPESVLKPELKRGFEYSDCWVDDARLVVLNAQEVEKRGGEVRTRTKVTRAWRENG
CCCCCCCHHHCCHHHHCCCCCCCEEECCCEEEEEEHHHHHHCCCCCHHHHHHHHHHHHCC
LWMVEAVDVDSGKTFTWRAKGLVNATGPWVKHFFDDGLKLKSPYGIRLIKGSHIVVPRVH
EEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCEECCCCCEEEEECCEEEEECCC
DQPQSYILQNEDHRIVFVIPWNDEFSIIGTTDVEYHGDPKDVKIDDNEINYLLKVYNDHF
CCCHHHHEECCCCEEEEEEECCCCEEEEECCCCEECCCCCCEEECCHHHHHHHHHHHHHH
KKQLGRDDIVWTYSGVRPLCDDESDSPQAVTRDYTLDVHDEQGKAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHCCCHHHHHH
LAEHAMEKLAHYYPGCGPAWTKNGSLPGGDIGGDRDSYAAKLRREHSWLPESLARRFART
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
YGSHSELILANANSLSDLGEDFGHGLHEAELRYLIDKEWVVELDDAIWRRTKLGMWLDEA
HCCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHCCCCHHHH
QQARVKAWLAEHVKAKTLSLAS
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]