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The map label for this gene is slyD [H]

Identifier: 157372790

GI number: 157372790

Start: 5032755

End: 5033357

Strand: Reverse

Name: slyD [H]

Synonym: Spro_4558

Alternate gene names: 157372790

Gene position: 5033357-5032755 (Counterclockwise)

Preceding gene: 157372791

Following gene: 157372788

Centisome position: 92.37

GC content: 56.55

Gene sequence:

>603_bases
ATGAAAGTAGCAAAAGACTTGGTGGTCAGCCTGGCTTACCAAGTACGTACAGAAGACGGTGTGTTGGTTGATGAGTCTCC
GGTGAGTGCGCCGCTGGACTATCTGCATGGGCATGGTTCACTGATTGCGGGTCTGGAAAAAGCACTCGAAGGCCACGAAG
CGGGCGATCGTTTTGACGTGAATGTTGGCGCTAACGATGCGTACGGCAACTACGACGAAAACCTGGTGCAGCGCGTGCCG
AAAGACGTCTTTATGGGCGTTGACGAGTTGGAAGTGGGTATGCGCTTCCTGGCTGATACCGATCAGGGCCCAGTGCCAGT
CGAAATCACCGAAGTGGACGGCGACCACGTAGTGGTTGACGGTAACCACATGCTGGCGGGTCAGAACCTGAACTTCAACG
TGGAAGTTGTCGCGATCCGCGAAGCTACCGCTGAAGAACTGGCGCACGGCCACGTACATGGCGAGCACGATCATCATCAC
GACCATGAACACGGTGAAGGCTGCTGCGGCGGTCATGGCCATGACCACGATCATGACCATGCACATGACCAGGCTCCGGC
CAAGAAAGGCGGTTGCGGTAACGGCGGTTGCGGTTGCCACTAA

Upstream 100 bases:

>100_bases
TGCTGAAGGGTACAGCGGGAAAGATTTCCGATACAATCTGTCCGGTTAAGGCGCGGCCCCCATGACGGTTGCGTCCAAGT
ATCCAACGGTAGGAGATATC

Downstream 100 bases:

>100_bases
TCGCAATGCTGTAACGGCAAAAAAAAGGGCGGCCCTGGGGCTGCCCTTTTTTATTGTTTATCAATAATGTGGCGGCGGAG
TCTCTTCCGACTGCGAAGCT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHEAGDRFDVNVGANDAYGNYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITEVDGDHVVVDGNHMLAGQNLNFNVEVVAIREATAEELAHGHVHGEHDHHH
DHEHGEGCCGGHGHDHDHDHAHDQAPAKKGGCGNGGCGCH

Sequences:

>Translated_200_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHEAGDRFDVNVGANDAYGNYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITEVDGDHVVVDGNHMLAGQNLNFNVEVVAIREATAEELAHGHVHGEHDHHH
DHEHGEGCCGGHGHDHDHDHAHDQAPAKKGGCGNGGCGCH
>Mature_200_residues
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHEAGDRFDVNVGANDAYGNYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITEVDGDHVVVDGNHMLAGQNLNFNVEVVAIREATAEELAHGHVHGEHDHHH
DHEHGEGCCGGHGHDHDHDHAHDQAPAKKGGCGNGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=91.2162162162162, Blast_Score=271, Evalue=2e-74,
Organism=Escherichia coli, GI1786211, Length=133, Percent_Identity=33.0827067669173, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21397; Mature: 21397

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHEAGDRFDV
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEE
NVGANDAYGNYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITEVDGDHVVVD
EECCCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLNFNVEVVAIREATAEELAHGHVHGEHDHHHDHEHGEGCCGGHGHDHDHDH
CCEEEECCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHDQAPAKKGGCGNGGCGCH
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLEKALEGHEAGDRFDV
CCHHHHHHHHHHHHEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCEEEE
NVGANDAYGNYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITEVDGDHVVVD
EECCCCCCCCCHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
GNHMLAGQNLNFNVEVVAIREATAEELAHGHVHGEHDHHHDHEHGEGCCGGHGHDHDHDH
CCEEEECCCCCCEEEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AHDQAPAKKGGCGNGGCGCH
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]