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The map label for this gene is gntK [H]

Identifier: 157372730

GI number: 157372730

Start: 4982800

End: 4983339

Strand: Direct

Name: gntK [H]

Synonym: Spro_4497

Alternate gene names: 157372730

Gene position: 4982800-4983339 (Clockwise)

Preceding gene: 157372729

Following gene: 157372731

Centisome position: 91.45

GC content: 57.59

Gene sequence:

>540_bases
ATGACCAATAATCAAAACCGCATTTACGTCATTATGGGCGTTTCCGGCAGTGGCAAGTCCGCTGTGGCCGCCGCTGCGGC
CCGCCAACTTTCTGCCGGGTTCCTCGACGGTGATTTTCTGCACCCGCGCAGTAATATCTTGAAAATGGCCGCCGGCGAAC
CGCTGAATGATGACGATCGTGCCCCTTGGCTGGCCGCACTTAATGACGCCGCCTTCGCCATGCAGCGAACCAACAATGTT
TCGGTTATCGTCTGTTCAGCGCTGAAGAAACACTACCGCGATCGCCTGCGTGCCGGTAATGGCAACCTGTCGTTCATCTA
CCTGCACGGTGACTTCCCGGTGATTGAAGCCCGCCTGGCGGCCCGCAACGGCCACTTCTTCAAACCGCAGATGCTGGTCA
CACAGTTTGCCGCGCTGGAACAACCGGGCGCAGATGAGAGCGACGTGATGTCGGTGGACATCAACCAGCCGCTGGAAGCG
GTGATCGCAGATACGGTGAAACATATCCAAAGTTTCCTGCCACAGGATGTGTGCGCGTGA

Upstream 100 bases:

>100_bases
CATTGCAACCGACGAAACTTCCTTCGACAATGTTACCGATAACATGTTACCGGTAACAAACAGAATAAGGTAACGTCTCT
CATCGTTTTGGAGCTAAGCC

Downstream 100 bases:

>100_bases
ATACTGTAACGCTGGTCGGTACCGCAGTCGGCTCGGTTCTCTTACTGCTGTTTCTGGTGATGAAGGCGCGTATGCACGCC
TTTGTCGCATTAATGCTGGT

Product: gluconate kinase 1

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTNNQNRIYVIMGVSGSGKSAVAAAAARQLSAGFLDGDFLHPRSNILKMAAGEPLNDDDRAPWLAALNDAAFAMQRTNNV
SVIVCSALKKHYRDRLRAGNGNLSFIYLHGDFPVIEARLAARNGHFFKPQMLVTQFAALEQPGADESDVMSVDINQPLEA
VIADTVKHIQSFLPQDVCA

Sequences:

>Translated_179_residues
MTNNQNRIYVIMGVSGSGKSAVAAAAARQLSAGFLDGDFLHPRSNILKMAAGEPLNDDDRAPWLAALNDAAFAMQRTNNV
SVIVCSALKKHYRDRLRAGNGNLSFIYLHGDFPVIEARLAARNGHFFKPQMLVTQFAALEQPGADESDVMSVDINQPLEA
VIADTVKHIQSFLPQDVCA
>Mature_178_residues
TNNQNRIYVIMGVSGSGKSAVAAAAARQLSAGFLDGDFLHPRSNILKMAAGEPLNDDDRAPWLAALNDAAFAMQRTNNVS
VIVCSALKKHYRDRLRAGNGNLSFIYLHGDFPVIEARLAARNGHFFKPQMLVTQFAALEQPGADESDVMSVDINQPLEAV
IADTVKHIQSFLPQDVCA

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=178, Percent_Identity=41.0112359550562, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI87082265, Length=170, Percent_Identity=74.7058823529412, Blast_Score=270, Evalue=3e-74,
Organism=Escherichia coli, GI1790719, Length=171, Percent_Identity=45.6140350877193, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25146487, Length=169, Percent_Identity=44.3786982248521, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320454, Length=157, Percent_Identity=36.9426751592357, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19425; Mature: 19294

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNQNRIYVIMGVSGSGKSAVAAAAARQLSAGFLDGDFLHPRSNILKMAAGEPLNDDDR
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
APWLAALNDAAFAMQRTNNVSVIVCSALKKHYRDRLRAGNGNLSFIYLHGDFPVIEARLA
CCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEHHHHH
ARNGHFFKPQMLVTQFAALEQPGADESDVMSVDINQPLEAVIADTVKHIQSFLPQDVCA
HCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
TNNQNRIYVIMGVSGSGKSAVAAAAARQLSAGFLDGDFLHPRSNILKMAAGEPLNDDDR
CCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
APWLAALNDAAFAMQRTNNVSVIVCSALKKHYRDRLRAGNGNLSFIYLHGDFPVIEARLA
CCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEHHHHH
ARNGHFFKPQMLVTQFAALEQPGADESDVMSVDINQPLEAVIADTVKHIQSFLPQDVCA
HCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]