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The map label for this gene is malF [H]

Identifier: 157372706

GI number: 157372706

Start: 4947039

End: 4948616

Strand: Direct

Name: malF [H]

Synonym: Spro_4473

Alternate gene names: 157372706

Gene position: 4947039-4948616 (Clockwise)

Preceding gene: 157372705

Following gene: 157372707

Centisome position: 90.79

GC content: 56.08

Gene sequence:

>1578_bases
ATGCAATTAGCTCACGCCGGTTCACCTGCGCGCAAAAAGTCGAAGTGGTGGCAGAGTGACATACTGAAATGGCTGGTTAT
CGGCCTGTTCAGCCTGGTTACCTGCTATCTGATTGTGTTGATGTATGCACAGGGTGAATACCTGTTTGCCATTCTGACGC
TGATTCTGGTCAGCGCCGGGCTTTACGTCTTCGCTAACCGCCGCGCTTATGCCTGGCGCTACGTTTATCCTGGCATCGCC
GGCATGGGGCTGTTTGTCCTGTTTCCGCTGATTTGCACTATCGCCATCGCCTTTACCAACTACAGCAGCACCAATCAGCT
CACCTTTGAGCGCGCCCAGTCGGTGCTGATGCAACGTCAATTCCAGACCGGCAAGACCTTTACCTTCGGCCTGTATCCGG
CGGAAAACCAACGCTGGCGTCTGCAGTTAACCCACCCGGACAACGGCCAGCAGCTGATTTCCCAGCCTTTCAGCTTTGAT
GCCAACGCACCGCAAACGCTAAAACTGGTCGAAGAAAGCGCCGAACCGGCAGGCGAGCGCGCCACGCTGCGGGTGATCAC
TCAAAACCGTCAGGCACTGAGCCAACTGGTGGCACAATTACCGGACGGCGGTGAGCTGCGCATGAGTTCCCTGCGCCAGT
TTTCCGGTACCAGTCCGCTTTACGCACTGGATAAGGACAGCAATGCGCTGACCGACCAACAGACCCATATTCAATACCGG
CCGAACCCGGAGATTGGCTTTTATCAGGCGGTGAATGCCGACGGTAACTGGGCAAAAGAGACCCTTAGCCCCGGCTATAC
CGTCACCATTGGCGGGAAAAACTTCCTGCGTGTGTTGCAGGACGAAGGCATCAAGAAGCCGTTCGTGTCGATCTTTATCT
GGACCATCGTGTTCTCGGTGATGACCGTGATCCTCACCGTGGCGGTAGGCATGGTGCTGGCCTGCGTGGTGCAGTGGGAA
GCGCTGAAAGGCAAAGCAATCTATCGCGTGATGCTGATACTGCCCTACGCGGTGCCGTCGTTTATTTCGATTCTGATTTT
CAAGGGGTTGTTCAACCAAAGCTTCGGTGAAATCAACATGATGCTCAGCCATCTGTTCGGTATCAAACCGGCCTGGTTCA
GCGACCCTGTCACCGCCAAAAGCATGATTTTGATCGTCAATACCTGGCTGGGTTATCCGTACATGATGATCCTGTGCATG
GGGCTGCTGAAGGCGATCCCGGACGACCTTTACGAGGCTTCGGCGATGGACGGCGCCACCCCGATGCAGAACTTTTTCCG
CATCACTCTGCCGCTGCTGATTAAACCGCTGACGCCGCTGATGATCGCCAGTTTCGCCTTCAACTTTAATAACTTCGTGC
TGATCCAACTGTTGACCAACGGCGGGCCGGACATGATCGGTACCACCACGCCGGCCGGTTATACCGACCTGCTGGTCAGC
TACACCTACCGCATCGCCTTCGAAGGCGGCGGCGGACAGGACTTCGGGCTGGCGGCGGCAATTGCCACGCTGATCTTCCT
GCTGGTGGGCGCCCTGGCGATCCTGAATCTGAAAGCCAGCAAGATGAACTTCGACTAG

Upstream 100 bases:

>100_bases
CGCGCTGGATGACGTACAAACCCGTATCACCAAGTAACACACTATGTTGTGCGGGGTGCAGACAGGCACCCCGCTGTGGC
TTCACAGAAAGGAACGCCCT

Downstream 100 bases:

>100_bases
GGAGAAAAATAATGGCTATGGTCCAACCCAAATCCCAGCGTCTGCGCCTGTGGATAACCCATGCACTGATGCTGTGCTTT
ATCGCCCTGATCATGTTCCC

Product: maltose transporter membrane protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MQLAHAGSPARKKSKWWQSDILKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAGLYVFANRRAYAWRYVYPGIA
GMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQFQTGKTFTFGLYPAENQRWRLQLTHPDNGQQLISQPFSFD
ANAPQTLKLVEESAEPAGERATLRVITQNRQALSQLVAQLPDGGELRMSSLRQFSGTSPLYALDKDSNALTDQQTHIQYR
PNPEIGFYQAVNADGNWAKETLSPGYTVTIGGKNFLRVLQDEGIKKPFVSIFIWTIVFSVMTVILTVAVGMVLACVVQWE
ALKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINMMLSHLFGIKPAWFSDPVTAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGATPMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD

Sequences:

>Translated_525_residues
MQLAHAGSPARKKSKWWQSDILKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAGLYVFANRRAYAWRYVYPGIA
GMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQFQTGKTFTFGLYPAENQRWRLQLTHPDNGQQLISQPFSFD
ANAPQTLKLVEESAEPAGERATLRVITQNRQALSQLVAQLPDGGELRMSSLRQFSGTSPLYALDKDSNALTDQQTHIQYR
PNPEIGFYQAVNADGNWAKETLSPGYTVTIGGKNFLRVLQDEGIKKPFVSIFIWTIVFSVMTVILTVAVGMVLACVVQWE
ALKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINMMLSHLFGIKPAWFSDPVTAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGATPMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD
>Mature_525_residues
MQLAHAGSPARKKSKWWQSDILKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAGLYVFANRRAYAWRYVYPGIA
GMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQFQTGKTFTFGLYPAENQRWRLQLTHPDNGQQLISQPFSFD
ANAPQTLKLVEESAEPAGERATLRVITQNRQALSQLVAQLPDGGELRMSSLRQFSGTSPLYALDKDSNALTDQQTHIQYR
PNPEIGFYQAVNADGNWAKETLSPGYTVTIGGKNFLRVLQDEGIKKPFVSIFIWTIVFSVMTVILTVAVGMVLACVVQWE
ALKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINMMLSHLFGIKPAWFSDPVTAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGATPMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=514, Percent_Identity=77.0428015564202, Blast_Score=800, Evalue=0.0,
Organism=Escherichia coli, GI1787570, Length=277, Percent_Identity=27.4368231046931, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789861, Length=254, Percent_Identity=29.1338582677165, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58383; Mature: 58383

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLAHAGSPARKKSKWWQSDILKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
LYVFANRRAYAWRYVYPGIAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQ
HHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FQTGKTFTFGLYPAENQRWRLQLTHPDNGQQLISQPFSFDANAPQTLKLVEESAEPAGER
HCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCC
ATLRVITQNRQALSQLVAQLPDGGELRMSSLRQFSGTSPLYALDKDSNALTDQQTHIQYR
EEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEC
PNPEIGFYQAVNADGNWAKETLSPGYTVTIGGKNFLRVLQDEGIKKPFVSIFIWTIVFSV
CCCCCCEEEEECCCCCHHHHHCCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MTVILTVAVGMVLACVVQWEALKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLSHLFGIKPAWFSDPVTAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAT
HHHHHHCCCCCCCCCCCCHHHEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
PMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHE
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
>Mature Secondary Structure
MQLAHAGSPARKKSKWWQSDILKWLVIGLFSLVTCYLIVLMYAQGEYLFAILTLILVSAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
LYVFANRRAYAWRYVYPGIAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLMQRQ
HHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FQTGKTFTFGLYPAENQRWRLQLTHPDNGQQLISQPFSFDANAPQTLKLVEESAEPAGER
HCCCCEEEEEEECCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCC
ATLRVITQNRQALSQLVAQLPDGGELRMSSLRQFSGTSPLYALDKDSNALTDQQTHIQYR
EEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEC
PNPEIGFYQAVNADGNWAKETLSPGYTVTIGGKNFLRVLQDEGIKKPFVSIFIWTIVFSV
CCCCCCEEEEECCCCCHHHHHCCCCEEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MTVILTVAVGMVLACVVQWEALKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINM
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
MLSHLFGIKPAWFSDPVTAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAT
HHHHHHCCCCCCCCCCCCHHHEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
PMQNFFRITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTTPAGYTDLLVS
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHE
YTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAILNLKASKMNFD
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]