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The map label for this gene is rbsR [C]

Identifier: 157372699

GI number: 157372699

Start: 4938948

End: 4939949

Strand: Direct

Name: rbsR [C]

Synonym: Spro_4466

Alternate gene names: 157372699

Gene position: 4938948-4939949 (Clockwise)

Preceding gene: 157372698

Following gene: 157372700

Centisome position: 90.64

GC content: 61.08

Gene sequence:

>1002_bases
TTGGATAATCAATCCGCGCGGCGTATCACCCGCGCCGACGTCGCCCGCGTAGCGGGCACCTCGGTCGCGGTAGTCAGCTA
TGTGATCAATAACGGTCCGCGCCCGGTGGCAGAAGCTACCCGTTTGCGGGTGCTGGCGGCGATCGAGCAAACCGGTTACC
GGCCGAACGACATCGCCCGGGCGCTGGCTTCGGGCAATACTCTGACTTATGGATTAGTGGTTCCCGATATTTCCAACCCG
TTTTTTGCCTCAATGGCACGGGCACTGCAGCGTGAAGCCTTCAACCATGGCCGCGTGCTGCTGTTGGGGGACGCCGGCGA
CGACCGGCAGCACGAGCACGACCTGATTAACCACCTGCTGCGCCGTCAGGTTGACGGGCTGCTGTATACCAGCGTCGATC
GTCATCCCTGGTTTGATCTGATCCGCAATTCCGGCACCCCCTGCGTGATGATAGATACCATCGACAGCCATGCCGGTATC
AGCGCCATCCGCGTTAATGAACGCGACGCCGCCTGCCAGGCCACACGCCATCTGTTGCAGCACGGCTACCGGGAGCTCGG
TATTTTTGTTGGCCCGCTGACCATGCTCAACGCACAAGATCGCCTTAACGGCTGGCGTGACGCGCTGATTGAGGCGGGTA
TTACGCCGCGTGAAGAATGGATTTTTGAAGCCCCCTATACCCGCAAGGGCGGCTATCAGGCCAGCCAGAAAATGCTGCAA
GGCCCCTGCCCACGCGCCATCTTCACCTCCAACGAACAACAGGCGCTCGGCTGTCTGTCAGCGCTGGCGGAACATCAACT
GCGCGTGCCGGACGATCTGGCTATCATTTGCTTTAACGGCACCCAACAATCCGAATTCAGCGTGCCGCCGCTCAGCGCGG
TCGAACAACCGATCGACGCCATGGCCAGGCAGGCCATCGCCATGTTGGCCACCGGTACCGCGCAGCCAGAACTGCACGAA
TTCGCCTTCCAGCTGCATATCCGCCGATCGTGCGGCTGCTAG

Upstream 100 bases:

>100_bases
GGCATTGGCTTAATCACCACCTTCTTTGCACCGGAAACCCGCGGCCGCGACCTTAACCTGCCGCAGGACGCGGTGTAATC
AGGGCGTACAGGAATCCAAC

Downstream 100 bases:

>100_bases
TTTATTGATTCAGGTAACTGCTATGCGTTTGATTATTGATTGCGATCCCGGCAACGGCATTCCCGGTGCCAACGTTGACG
ACGGGCTGGCGCTGGCGCTG

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDNQSARRITRADVARVAGTSVAVVSYVINNGPRPVAEATRLRVLAAIEQTGYRPNDIARALASGNTLTYGLVVPDISNP
FFASMARALQREAFNHGRVLLLGDAGDDRQHEHDLINHLLRRQVDGLLYTSVDRHPWFDLIRNSGTPCVMIDTIDSHAGI
SAIRVNERDAACQATRHLLQHGYRELGIFVGPLTMLNAQDRLNGWRDALIEAGITPREEWIFEAPYTRKGGYQASQKMLQ
GPCPRAIFTSNEQQALGCLSALAEHQLRVPDDLAIICFNGTQQSEFSVPPLSAVEQPIDAMARQAIAMLATGTAQPELHE
FAFQLHIRRSCGC

Sequences:

>Translated_333_residues
MDNQSARRITRADVARVAGTSVAVVSYVINNGPRPVAEATRLRVLAAIEQTGYRPNDIARALASGNTLTYGLVVPDISNP
FFASMARALQREAFNHGRVLLLGDAGDDRQHEHDLINHLLRRQVDGLLYTSVDRHPWFDLIRNSGTPCVMIDTIDSHAGI
SAIRVNERDAACQATRHLLQHGYRELGIFVGPLTMLNAQDRLNGWRDALIEAGITPREEWIFEAPYTRKGGYQASQKMLQ
GPCPRAIFTSNEQQALGCLSALAEHQLRVPDDLAIICFNGTQQSEFSVPPLSAVEQPIDAMARQAIAMLATGTAQPELHE
FAFQLHIRRSCGC
>Mature_333_residues
MDNQSARRITRADVARVAGTSVAVVSYVINNGPRPVAEATRLRVLAAIEQTGYRPNDIARALASGNTLTYGLVVPDISNP
FFASMARALQREAFNHGRVLLLGDAGDDRQHEHDLINHLLRRQVDGLLYTSVDRHPWFDLIRNSGTPCVMIDTIDSHAGI
SAIRVNERDAACQATRHLLQHGYRELGIFVGPLTMLNAQDRLNGWRDALIEAGITPREEWIFEAPYTRKGGYQASQKMLQ
GPCPRAIFTSNEQQALGCLSALAEHQLRVPDDLAIICFNGTQQSEFSVPPLSAVEQPIDAMARQAIAMLATGTAQPELHE
FAFQLHIRRSCGC

Specific function: Transcriptional Repressor For The Ribose Rbsdacbk Operon. Rbsr Binds To A Region Of Perfect Dyad Symmetry Spanning The Rbs Operon Transcriptional Start Site. The Affinity For The Rbs Operator Is Reduced By Addition Of Ribose, Consistent With Ribose Being

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=32.9153605015674, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1789202, Length=298, Percent_Identity=36.241610738255, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1790369, Length=303, Percent_Identity=32.6732673267327, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787948, Length=304, Percent_Identity=32.2368421052632, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=29.6416938110749, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788474, Length=323, Percent_Identity=31.8885448916409, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786268, Length=316, Percent_Identity=28.4810126582279, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787580, Length=308, Percent_Identity=25.3246753246753, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786540, Length=294, Percent_Identity=27.5510204081633, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=24.6913580246914, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787906, Length=262, Percent_Identity=29.0076335877863, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790715, Length=306, Percent_Identity=23.5294117647059, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36728; Mature: 36728

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQSARRITRADVARVAGTSVAVVSYVINNGPRPVAEATRLRVLAAIEQTGYRPNDIAR
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
ALASGNTLTYGLVVPDISNPFFASMARALQREAFNHGRVLLLGDAGDDRQHEHDLINHLL
HHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
RRQVDGLLYTSVDRHPWFDLIRNSGTPCVMIDTIDSHAGISAIRVNERDAACQATRHLLQ
HHHHCCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHH
HGYRELGIFVGPLTMLNAQDRLNGWRDALIEAGITPREEWIFEAPYTRKGGYQASQKMLQ
HCHHHHHEEECCHHHCCCHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCCHHHHHHHC
GPCPRAIFTSNEQQALGCLSALAEHQLRVPDDLAIICFNGTQQSEFSVPPLSAVEQPIDA
CCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
MARQAIAMLATGTAQPELHEFAFQLHIRRSCGC
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDNQSARRITRADVARVAGTSVAVVSYVINNGPRPVAEATRLRVLAAIEQTGYRPNDIAR
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
ALASGNTLTYGLVVPDISNPFFASMARALQREAFNHGRVLLLGDAGDDRQHEHDLINHLL
HHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
RRQVDGLLYTSVDRHPWFDLIRNSGTPCVMIDTIDSHAGISAIRVNERDAACQATRHLLQ
HHHHCCCEEECCCCCHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHH
HGYRELGIFVGPLTMLNAQDRLNGWRDALIEAGITPREEWIFEAPYTRKGGYQASQKMLQ
HCHHHHHEEECCHHHCCCHHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCCCHHHHHHHC
GPCPRAIFTSNEQQALGCLSALAEHQLRVPDDLAIICFNGTQQSEFSVPPLSAVEQPIDA
CCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
MARQAIAMLATGTAQPELHEFAFQLHIRRSCGC
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953; 7688332 [H]