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The map label for this gene is ywbI [H]

Identifier: 157372662

GI number: 157372662

Start: 4901459

End: 4902346

Strand: Direct

Name: ywbI [H]

Synonym: Spro_4429

Alternate gene names: 157372662

Gene position: 4901459-4902346 (Clockwise)

Preceding gene: 157372659

Following gene: 157372668

Centisome position: 89.95

GC content: 59.12

Gene sequence:

>888_bases
GTGGATGTCCGCACTTTGCGCTACTTCGTGGAAGTGGTGCGCCAGCAAAGCTTTACCCGCGCGGCGGAAAAACTGTTCGT
CACCCAGCCGACCATCAGCAAGATGCTGCGCCATCTTGAAGAGGAGCTGGAGTGCACCTTGCTGATCCGCGAAGGCCGCA
GGCTGCACCTGACCGACAGCGGCCAGGCGGTATATCAGCGCGGTCTGGCCATCATCGATGAATTCCGCCAGTTGGAAGCC
GAGCTGGAAGACATCAGCTCGGTGAAAAAAGGCGTGCTGCGGTTGGGCATCCCACCGATGGTCGGCCGGCAGATTGCCGA
TTTGATCCGGCAGTTTCGCCAGACTTATCCCGGCATCGAACTCAAAATCTCCGAACTGGGCGGGCTATCGGTTGAACAGG
CGGTGATGTCCGGTGAACTGGATCTGGCGATGACCATTCTGCCGGTCGATTCCGCTCAGCCACTGACCTTTCTGCCCTTG
CTCGGCCACCCCATGTGCGTGGTCGCACCACGAACGCCGCACTGGTTAAACCGTACCAGTATCCATATCTCCGAGTTGGC
CAACTGGCCGATCCTGCTTTATAACGAGGACTTCGCGCTCTACAAGATGCTGATGACAGCATTCCGCCAGGCCGGTTTTG
AACCCCAGATTGCGGTACGCAGCGGGCAATGGGATTTTCTGGCGTCGATGGTGCAGGCCGGGGTTGGCATCGCCACCCTG
CCGGAGCCGGTCTGCCAATGGCTGGATAAGGAAAACCTGATTTGGCTGCCGCTGGAGCCACGCATGGAATGGAAGGTGGG
GTTAATCTGGCGTCAGGGCAGCTACCTGTCACACAGCGCCCAGGCCTGGATCGCCTGTTGTCGCGACTACTGGCCGTCGA
TGAAATAA

Upstream 100 bases:

>100_bases
TACGCAGCCAGGAAACCCCGCCTGAAATGAATTAAAATTATCAATATCATGCCATCAGGGAATAATTTCCCGCTGGTATT
GTTCCTGAGGAGAACCCAAC

Downstream 100 bases:

>100_bases
ACGGGGCCGCGTCTGCGGCCCCATTGGCATTACCCCTCGCGCTCTATCAACAGCGCTTCCAGCAGGTCGAGATCGTGCAA
TAATTTTTGCAGCGTCTCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDVRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLRHLEEELECTLLIREGRRLHLTDSGQAVYQRGLAIIDEFRQLEA
ELEDISSVKKGVLRLGIPPMVGRQIADLIRQFRQTYPGIELKISELGGLSVEQAVMSGELDLAMTILPVDSAQPLTFLPL
LGHPMCVVAPRTPHWLNRTSIHISELANWPILLYNEDFALYKMLMTAFRQAGFEPQIAVRSGQWDFLASMVQAGVGIATL
PEPVCQWLDKENLIWLPLEPRMEWKVGLIWRQGSYLSHSAQAWIACCRDYWPSMK

Sequences:

>Translated_295_residues
MDVRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLRHLEEELECTLLIREGRRLHLTDSGQAVYQRGLAIIDEFRQLEA
ELEDISSVKKGVLRLGIPPMVGRQIADLIRQFRQTYPGIELKISELGGLSVEQAVMSGELDLAMTILPVDSAQPLTFLPL
LGHPMCVVAPRTPHWLNRTSIHISELANWPILLYNEDFALYKMLMTAFRQAGFEPQIAVRSGQWDFLASMVQAGVGIATL
PEPVCQWLDKENLIWLPLEPRMEWKVGLIWRQGSYLSHSAQAWIACCRDYWPSMK
>Mature_295_residues
MDVRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLRHLEEELECTLLIREGRRLHLTDSGQAVYQRGLAIIDEFRQLEA
ELEDISSVKKGVLRLGIPPMVGRQIADLIRQFRQTYPGIELKISELGGLSVEQAVMSGELDLAMTILPVDSAQPLTFLPL
LGHPMCVVAPRTPHWLNRTSIHISELANWPILLYNEDFALYKMLMTAFRQAGFEPQIAVRSGQWDFLASMVQAGVGIATL
PEPVCQWLDKENLIWLPLEPRMEWKVGLIWRQGSYLSHSAQAWIACCRDYWPSMK

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=28.3154121863799, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=26.8292682926829, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI145693105, Length=308, Percent_Identity=25.3246753246753, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=30, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787879, Length=266, Percent_Identity=25.5639097744361, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=26.5151515151515, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=26.3374485596708, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789506, Length=288, Percent_Identity=22.2222222222222, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790208, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=256, Percent_Identity=25.390625, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788296, Length=283, Percent_Identity=22.6148409893993, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787806, Length=281, Percent_Identity=24.9110320284698, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI2367136, Length=271, Percent_Identity=22.8782287822878, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=24.3986254295533, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693193, Length=257, Percent_Identity=25.6809338521401, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=297, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789173, Length=144, Percent_Identity=32.6388888888889, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789440, Length=119, Percent_Identity=32.7731092436975, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787949, Length=269, Percent_Identity=24.1635687732342, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081978, Length=123, Percent_Identity=31.7073170731707, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33748; Mature: 33748

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLRHLEEELECTLLIREGRRLHLTDS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCEEEEECC
GQAVYQRGLAIIDEFRQLEAELEDISSVKKGVLRLGIPPMVGRQIADLIRQFRQTYPGIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
LKISELGGLSVEQAVMSGELDLAMTILPVDSAQPLTFLPLLGHPMCVVAPRTPHWLNRTS
EEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHCCCCEEEECCCCCCCCCCCC
IHISELANWPILLYNEDFALYKMLMTAFRQAGFEPQIAVRSGQWDFLASMVQAGVGIATL
EEHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
PEPVCQWLDKENLIWLPLEPRMEWKVGLIWRQGSYLSHSAQAWIACCRDYWPSMK
CHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDVRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLRHLEEELECTLLIREGRRLHLTDS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCEEEEECC
GQAVYQRGLAIIDEFRQLEAELEDISSVKKGVLRLGIPPMVGRQIADLIRQFRQTYPGIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCE
LKISELGGLSVEQAVMSGELDLAMTILPVDSAQPLTFLPLLGHPMCVVAPRTPHWLNRTS
EEECCCCCCHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHCCCCEEEECCCCCCCCCCCC
IHISELANWPILLYNEDFALYKMLMTAFRQAGFEPQIAVRSGQWDFLASMVQAGVGIATL
EEHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCCCCCC
PEPVCQWLDKENLIWLPLEPRMEWKVGLIWRQGSYLSHSAQAWIACCRDYWPSMK
CHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]