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The map label for this gene is yrbG [H]

Identifier: 157372594

GI number: 157372594

Start: 4831620

End: 4832597

Strand: Direct

Name: yrbG [H]

Synonym: Spro_4361

Alternate gene names: 157372594

Gene position: 4831620-4832597 (Clockwise)

Preceding gene: 157372586

Following gene: 157372595

Centisome position: 88.67

GC content: 55.83

Gene sequence:

>978_bases
ATGTTTCTCGCGATAGTTTTATTAATCGTTGGTTTATTTTTACTGGTGTATGGCGCAGACCGCTTAGTTTACGGTGCTGC
GGTGATTTCTCGTTCACTTGGTGTGCCACCGCTGATTATCGGCATGACCATCGTCGGCATCGGCACTTCGCTGCCGGAAC
TGTTTGTTTCGACCACCGCCGCGCTGAACGGGCAGATAGATATGGCGGTGGGAAACGTAATTGGTTCCAACATCACCAAT
ATTCTCTTGATCCTCGGCGTTGCCGCGCTGATCCACCCGCTGGCTGCACGTTCTGAAGTGTTGCGACGCGAACTGCCGCT
GATGTTGGCGGTCACAGTATTGTGCGGTTTCGTGCTGATGGACGGCACGCTAAGTCGGCTGGATGGCGTGGTGCTGTTGG
CCGCCGCCGCCATCTTCATTCTGCTGATGTTGAAAATTGCCCGGCTGGCACAGCGTGAAGGCAACGACAGCCTGACCGTG
GAACAAATGGCCGAGCTGCCGCAGGACAGCAGCAACACCGTGGCGGTGCTGTGGCTGGTGCTGGCGTTTATCATTCTGCC
GCTGTCTTCCAAAATGGTGGTCGATAACGCCACGGTGATCGCGCACTTTTTCGGTATGAGTGAGCTGGTGGTCGGCCTGA
CCCTTATCGCTGTCGGCACCAGCCTGCCGGAGCTGGCGACCTCCATCGCCGGAGCACTAAAGGGTGAGGATGATATGGCG
ATTGGCAATATCATCGGCTCCAACATTTTCAATACGGTGATAGTGCTGGGTGTCCCCGCCCTGCTGTCCCCTGGCAGTGT
CGATGGCGCCGCCTTCCACCGCGATTACTGGGTGATGCTGGCGGTCAGCATTGTGCTCACCGCCTTGTGCGTTGGGCGTA
AACATCGCATCGGTCATCTGGCAGGGGCTCTGTTATTATGTGGCTTTATTGCGTATCTTGCGGTGCTGTTTTTTAACCCT
TTCAGTACTTTCGGCTAA

Upstream 100 bases:

>100_bases
GTTGCTGCGGATTTTGCCTGCGCAACGGAGGGCAAAGCAAGATAGCCGAATTACGGCTTTTAACCAACGAACCGGGATAA
TTCCCAACAAAGGACCCTGC

Downstream 100 bases:

>100_bases
ACCGACGAGCGGGAATGAGTATGTCGAACATTCAGTTGCAACCAGGCTTTGATTTTCAGCAGGCAGGCAAAGAAGTGCTG
CAGATTGAGCGTGACGGGCT

Product: putative calcium/sodium:proton antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFLAIVLLIVGLFLLVYGADRLVYGAAVISRSLGVPPLIIGMTIVGIGTSLPELFVSTTAALNGQIDMAVGNVIGSNITN
ILLILGVAALIHPLAARSEVLRRELPLMLAVTVLCGFVLMDGTLSRLDGVVLLAAAAIFILLMLKIARLAQREGNDSLTV
EQMAELPQDSSNTVAVLWLVLAFIILPLSSKMVVDNATVIAHFFGMSELVVGLTLIAVGTSLPELATSIAGALKGEDDMA
IGNIIGSNIFNTVIVLGVPALLSPGSVDGAAFHRDYWVMLAVSIVLTALCVGRKHRIGHLAGALLLCGFIAYLAVLFFNP
FSTFG

Sequences:

>Translated_325_residues
MFLAIVLLIVGLFLLVYGADRLVYGAAVISRSLGVPPLIIGMTIVGIGTSLPELFVSTTAALNGQIDMAVGNVIGSNITN
ILLILGVAALIHPLAARSEVLRRELPLMLAVTVLCGFVLMDGTLSRLDGVVLLAAAAIFILLMLKIARLAQREGNDSLTV
EQMAELPQDSSNTVAVLWLVLAFIILPLSSKMVVDNATVIAHFFGMSELVVGLTLIAVGTSLPELATSIAGALKGEDDMA
IGNIIGSNIFNTVIVLGVPALLSPGSVDGAAFHRDYWVMLAVSIVLTALCVGRKHRIGHLAGALLLCGFIAYLAVLFFNP
FSTFG
>Mature_325_residues
MFLAIVLLIVGLFLLVYGADRLVYGAAVISRSLGVPPLIIGMTIVGIGTSLPELFVSTTAALNGQIDMAVGNVIGSNITN
ILLILGVAALIHPLAARSEVLRRELPLMLAVTVLCGFVLMDGTLSRLDGVVLLAAAAIFILLMLKIARLAQREGNDSLTV
EQMAELPQDSSNTVAVLWLVLAFIILPLSSKMVVDNATVIAHFFGMSELVVGLTLIAVGTSLPELATSIAGALKGEDDMA
IGNIIGSNIFNTVIVLGVPALLSPGSVDGAAFHRDYWVMLAVSIVLTALCVGRKHRIGHLAGALLLCGFIAYLAVLFFNP
FSTFG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=318, Percent_Identity=60.062893081761, Blast_Score=325, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 34072; Mature: 34072

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAIVLLIVGLFLLVYGADRLVYGAAVISRSLGVPPLIIGMTIVGIGTSLPELFVSTTA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ALNGQIDMAVGNVIGSNITNILLILGVAALIHPLAARSEVLRRELPLMLAVTVLCGFVLM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGTLSRLDGVVLLAAAAIFILLMLKIARLAQREGNDSLTVEQMAELPQDSSNTVAVLWLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCHHHHHHHH
LAFIILPLSSKMVVDNATVIAHFFGMSELVVGLTLIAVGTSLPELATSIAGALKGEDDMA
HHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
IGNIIGSNIFNTVIVLGVPALLSPGSVDGAAFHRDYWVMLAVSIVLTALCVGRKHRIGHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AGALLLCGFIAYLAVLFFNPFSTFG
HHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MFLAIVLLIVGLFLLVYGADRLVYGAAVISRSLGVPPLIIGMTIVGIGTSLPELFVSTTA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
ALNGQIDMAVGNVIGSNITNILLILGVAALIHPLAARSEVLRRELPLMLAVTVLCGFVLM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGTLSRLDGVVLLAAAAIFILLMLKIARLAQREGNDSLTVEQMAELPQDSSNTVAVLWLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCCCHHHHHHHH
LAFIILPLSSKMVVDNATVIAHFFGMSELVVGLTLIAVGTSLPELATSIAGALKGEDDMA
HHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
IGNIIGSNIFNTVIVLGVPALLSPGSVDGAAFHRDYWVMLAVSIVLTALCVGRKHRIGHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AGALLLCGFIAYLAVLFFNPFSTFG
HHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]