Click here to switch to the map view.

The map label for this gene is gltB [H]

Identifier: 157372577

GI number: 157372577

Start: 4813347

End: 4817807

Strand: Direct

Name: gltB [H]

Synonym: Spro_4344

Alternate gene names: 157372577

Gene position: 4813347-4817807 (Clockwise)

Preceding gene: 157372572

Following gene: 157372578

Centisome position: 88.34

GC content: 59.27

Gene sequence:

>4461_bases
ATGTTGTACGATAAATCCCAAGAGCGGGACAACTGTGGTTTCGGCCTGATCGCCCACATAGAAGGCGAACCTAGCCATAA
GGTGGTGCGTACCGCTATTCACGCACTTGCCCGTATGCAGCACCGTGGCGCAATCCTTGCTGACGGCAAGACTGGCGACG
GTTGCGGCCTGTTATTGCAAAAGCCCGATCGCTTCTTCCGCATGGTCGCAGAAGAGCGCAGCTGGCGTTTAGCCAAGAAC
TACGCCGTTGGCATGATGTTCCTCAGCCAGAACGAAGAGGAAGCCCGTGCCAGCCGCCGCATTGTCGAAGAAGAGCTGCA
GAATGAAACGCTGTCGGTAGTCGGCTGGCGTGAAGTGCCGACCAACCCGGACGTATTGGGTGAGATTGCCCTCTCTTCTC
TGCCACGCATTGAACAAATCTTCGTGAACGCCCCGGCCGGTTGGCGTCCGCGTGATATGGAACGCCGCCTGTTTATCGCG
CGTCGCCGTATCGAGAAGCGCGTCCAGGACGACAGCTTCTACGTCTGCAGCTTCTCGAATCTGGTGACGATCTATAAAGG
CCTGTGCATGCCTGCGGATCTGCCGCGTTTTTATCTTGATTTGGCGGACTTGCGCCTGGAATCGGCCATCTGCCTGTTCC
ACCAGCGTTTTTCCACCAACACCGTGCCGCGCTGGCCGCTGGCGCAGCCGTTCCGCTATCTGGCGCACAACGGCGAGATC
AATACCATCACCGGCAACCGTCAGTGGGCGCGCGCCCGTACTTATAAGTTCCAGACGCCGCTGATCCCGGACTTGCAGAC
TGCTGCCCCCTTCGTTAACGAAACCGGCTCCGACTCCAGTTCGCTGGATAACATGCTGGAACTGCTGCTGGCGGGCGGGA
TGGATCTGATCCGTGCCATGCGCCTGCTGGTGCCGCCGGCCTGGCAGAACAACCCGGATATGGACACCGATCTGCGCGCC
TTCTTCGACTTCAACTCGATGCACATGGAGCCGTGGGACGGCCCTGCCGGCATCGTGATGTCCGATGGCCGCTACGCTGC
CTGTAACCTGGACCGTAACGGCCTGCGTCCGGCGCGCTACGTCATCACCAAAGACAAGCTGATCACCTGCGCCTCGGAAG
TCGGTATCTGGGACTACCAGCCCGATGAAGTGGTTGAGAAAGGCCGCGTGGGCCCTGGCGAGCTGATGGTGATCGACACC
CGCAGCGGCAGGATCCTGCACTCCGCCGAGACCGACGACGATCTGAAAAGCCGCCATCCGTATAAAGAGTGGATGGAAAA
GAACGTCAAACGTCTGGTGCCATTCGAAGATCTACCGGCCGATCAGGTTGGCAGCCGTGAGCTTGACGACTCGCAGCTTG
AGACTTACCAGAAACAGTTCGGCTACAGCAGCGAAGAACTGGATCAGGTGATCCGCGTGCTGGGTGAGATTGGCCAGGAA
GCCACGGGTTCAATGGGTGACGATACCCCGTTCGCCGTGCTCTCCAGCCGTCCGCGCATTATTTATGACTATTTCCGTCA
GCAGTTTGCCCAGGTGACCAACCCACCGATCGACCCGCTGCGTGAAGCGCATGTGATGTCGCTGGCGACCAGCATCGGCC
GCGAAATGAACGTGTTCTGCGAGGCCGAAGGCCAGGCACACCGTTTAAGCTTCAAATCGCCGATCCTGCTGTACTCCGAC
TTCAAACAGCTCACCACGCTGGAAGGCGAATACTATCGCGCCGATACGCTTGATCTGACCTTTGATCCGGCGGAGCAGGA
TTTGGAGCAGACCATCCGCGCGCTATGCGACGAAGCGGAACGCAAAGTCCGCGACGGCGCCGTGCTGCTGGTATTGTCCG
ACCGCGCGATCTCCACCAGCCGTCTGCCGGTGCCTGCACCGATGGCCGTAGGGGCGATCCAGACCCGTCTGGTAGAGAAA
AGCCTGCGCTGTGACGCCAACATCATTGTTGAAACCGCCAGCGCCCGCGATCCACACCATTTCGCCGTGTTGCTGGGCTT
CGGTGCAACGGCGGTCTACCCATACCTGGCCTACGAAACCCTGGCCAAACTGGTAGATACCCAGGCGATCGACAAGAAAT
ACCGTGAAGTGATGCTGAACTACCGTAATGGCATCAACAAAGGCCTGTACAAGATCATGTCCAAAATGGGCATTTCGACC
ATTGCCTCTTACCGCTGCGCCAAACTGTTCGAGGCCGTCGGTCTGCATCGCGATCTGTCCGATCTGTGTTTCCAGGGCGT
GGTCAGCCGTATCGGCGGTGCCAGCTTCAGTGACATCCAACAGGATCTGCAAAACCTGTCCAAGCGCGCGTGGCTGAAAC
GCAAACCGCTGGAACAAGGCGGCCTGCTGAAGTTCGTCCACGACGGCGAGTACCATGCGTACAACCCTGACGTGGTCAGC
ACGCTGCAAACCGCGGTCCACAGCGGCAAATACAGCGACTATCAGACTTACGCCAAGCTGGTGAATGAACGCCCGGTGGC
AATGCTGCGCGACCTGTTGGCCATCACGCCGAAAGGCACGCCAATCCCGGTCGATCAGGTTGAACCGGCAGAATCGCTGT
TCAAACGCTTCGATACCGCGGCCATGTCTATCGGCGCCCTGAGCCCGGAAGCGCATGAGTCGCTGGCCATCGCCATGAAC
AGCCTCGGCGGCTTCTCCAACTCCGGCGAGGGCGGCGAAGATCCGGCACGTTACGGCACCAACAAGGTGTCACGCATCAA
GCAGGTGGCATCCGGCCGTTTCGGCGTGACTCCGGCCTACCTGGTAAATGCCGATGTGATCCAAATTAAAGTGGCGCAAG
GGGCCAAGCCGGGTGAAGGCGGCCAGTTGCCGGGCGACAAGGTGACCCCTTATATCGCCAAGCTGCGTTACTCGGTACCG
GGCGTGACCCTGATATCGCCACCGCCGCACCACGACATCTACTCGATCGAAGATCTGGCGCAGTTGATTTTCGACCTGAA
ACAGGTCAACCCGAAGGCGATGATTTCGGTAAAACTGGTGTCAGAACCGGGCGTGGGTACCATTGCCACCGGCGTGGCGA
AAGCCTATGCCGACCTGATCACCATTGCCGGCTACGACGGCGGTACCGGTGCCAGCCCACTGTCTTCGGTAAAATACGCC
GGCTGTCCGTGGGAACTGGGTCTGGTGGAAACACAGCAGGCGCTGGTGGCTAACGGCCTGCGCCATAAAATCCGCTTGCA
GGTAGACGGTGGCCTGAAAACCGGCGTGGATATCGTCAAAGCGGCGATCCTCGGTGCGGAAAGCTTTGGCTTCGGCACCG
GCCCTATGGTGGCGCTGGGCTGTAAATATCTGCGTATCTGTCACCTGAATAACTGCGCAACCGGCGTAGCAACTCAGGAT
GAAAAACTGCGCCGCGATCACTACCACGGCCTGCCGGAACGTGTGGTTAATTACTTCCAGTTTATCGCCCGTGAAACCCG
CGAGATTATGGCGCAACTGGGCGTCAGCCAACTGGTAGATCTGATTGGCCGCACCGAGTTCCTGACCGAGTTGGATGGCA
TTTCTGCCAAGCAGAACAAGCTGGATCTGTCACCGTTGCTGCAAACCGCCACGCCGCATCCGGGCAAGGCGCTGTACTGC
ACCGAAAGCAGCAACCCGCCGTTCGACCAGGGGTTGATGAACAAAGATCTGCTGGCGCAGGCGCAACCGCATATCGAAGC
CAGACAAAGCAAGGCTTTCTACTTCGATATCCGCAATACCGACCGTTCGGTGGGCGCGACCCTGTCCGGGGCTATCGCTA
CCGTGCACGGCGATCAGGGCATGGCTGCCGACCCGATCAAGGCGTACTTCTCCGGTACCGCCGGCCAGAGTTTCGGCGTC
TGGAATGCGGGTGGGGTTGAACTGACCCTGACCGGCGACGCCAACGACTACGTTGGTAAAGGCATGGCCGGTGGCCGTAT
CGCGGTACGTCCGCCGATTGGTTCTGCGTTCCGCAGCCACGAAGCCAGCATCATCGGCAATACCTGTTTGTATGGTGCGA
CCGGCGGCAAGTTGTTCGCCGCTGGCCGGGCAGGCGAACGCTTTGCCGTGCGTAACTCCGGTGCCATCACCGTCGTCGAA
GGTATCGGTGACAACGGGTGTGAATACATGACCGGCGGTATTGTCTGCGTAATGGGCAAAACCGGCATCAACTTTGGTGC
GGGGATGACCGGCGGCTTCGCCTACGTGCTGGATGAAGACGGCGAGTTCCGCAAACGTGTGAATCCAGAGTTGGTGGAAG
TGTTGGATGTCGAACAACTGGCTATCCATGAAGAGCACCTGCGCGGCTTGATTACCGAGCACGTCCAGGCGACCGGTTCT
TCGCGTGCGGAAGAGATCCTGGCCAACTGGCCGGAATGGGCACCGAAGTTCGCTCTGGTCAAGCCGAAGTCCAGTGATGT
CAAAGCATTGTTGGGTCACCGTAGTCGAACCGCTGCCGAGCTGCGGGTTCAGGCGCAGTAA

Upstream 100 bases:

>100_bases
TCGGCGCTATTAACCTTGCTGATTGGACTTCTGCCTGAAATTAAGAAGCCGCTCGCAGTGGGTTGTGAGAGTCACGCAGA
GCCTGGGGAGGTTCACTGAT

Downstream 100 bases:

>100_bases
GAGGTCATTAATGAGTCAGAATGTTTATCAATTTATCGACCTGCAGCGCGTTGATCCGCCAAAGAAACCGCTCAAGATCC
GTAAAATTGAGTTTGTAGAG

Product: glutamate synthase subunit alpha

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1486; Mature: 1486

Protein sequence:

>1486_residues
MLYDKSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRMVAEERSWRLAKN
YAVGMMFLSQNEEEARASRRIVEEELQNETLSVVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRVQDDSFYVCSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTITGNRQWARARTYKFQTPLIPDLQTAAPFVNETGSDSSSLDNMLELLLAGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGRILHSAETDDDLKSRHPYKEWMEKNVKRLVPFEDLPADQVGSRELDDSQLETYQKQFGYSSEELDQVIRVLGEIGQE
ATGSMGDDTPFAVLSSRPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FKQLTTLEGEYYRADTLDLTFDPAEQDLEQTIRALCDEAERKVRDGAVLLVLSDRAISTSRLPVPAPMAVGAIQTRLVEK
SLRCDANIIVETASARDPHHFAVLLGFGATAVYPYLAYETLAKLVDTQAIDKKYREVMLNYRNGINKGLYKIMSKMGIST
IASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDIQQDLQNLSKRAWLKRKPLEQGGLLKFVHDGEYHAYNPDVVS
TLQTAVHSGKYSDYQTYAKLVNERPVAMLRDLLAITPKGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFQFIARETREIMAQLGVSQLVDLIGRTEFLTELDGISAKQNKLDLSPLLQTATPHPGKALYC
TESSNPPFDQGLMNKDLLAQAQPHIEARQSKAFYFDIRNTDRSVGATLSGAIATVHGDQGMAADPIKAYFSGTAGQSFGV
WNAGGVELTLTGDANDYVGKGMAGGRIAVRPPIGSAFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVE
GIGDNGCEYMTGGIVCVMGKTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQATGS
SRAEEILANWPEWAPKFALVKPKSSDVKALLGHRSRTAAELRVQAQ

Sequences:

>Translated_1486_residues
MLYDKSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRMVAEERSWRLAKN
YAVGMMFLSQNEEEARASRRIVEEELQNETLSVVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRVQDDSFYVCSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTITGNRQWARARTYKFQTPLIPDLQTAAPFVNETGSDSSSLDNMLELLLAGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGRILHSAETDDDLKSRHPYKEWMEKNVKRLVPFEDLPADQVGSRELDDSQLETYQKQFGYSSEELDQVIRVLGEIGQE
ATGSMGDDTPFAVLSSRPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FKQLTTLEGEYYRADTLDLTFDPAEQDLEQTIRALCDEAERKVRDGAVLLVLSDRAISTSRLPVPAPMAVGAIQTRLVEK
SLRCDANIIVETASARDPHHFAVLLGFGATAVYPYLAYETLAKLVDTQAIDKKYREVMLNYRNGINKGLYKIMSKMGIST
IASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDIQQDLQNLSKRAWLKRKPLEQGGLLKFVHDGEYHAYNPDVVS
TLQTAVHSGKYSDYQTYAKLVNERPVAMLRDLLAITPKGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFQFIARETREIMAQLGVSQLVDLIGRTEFLTELDGISAKQNKLDLSPLLQTATPHPGKALYC
TESSNPPFDQGLMNKDLLAQAQPHIEARQSKAFYFDIRNTDRSVGATLSGAIATVHGDQGMAADPIKAYFSGTAGQSFGV
WNAGGVELTLTGDANDYVGKGMAGGRIAVRPPIGSAFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVE
GIGDNGCEYMTGGIVCVMGKTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQATGS
SRAEEILANWPEWAPKFALVKPKSSDVKALLGHRSRTAAELRVQAQ
>Mature_1486_residues
MLYDKSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRMVAEERSWRLAKN
YAVGMMFLSQNEEEARASRRIVEEELQNETLSVVGWREVPTNPDVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRVQDDSFYVCSFSNLVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
NTITGNRQWARARTYKFQTPLIPDLQTAAPFVNETGSDSSSLDNMLELLLAGGMDLIRAMRLLVPPAWQNNPDMDTDLRA
FFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDT
RSGRILHSAETDDDLKSRHPYKEWMEKNVKRLVPFEDLPADQVGSRELDDSQLETYQKQFGYSSEELDQVIRVLGEIGQE
ATGSMGDDTPFAVLSSRPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSD
FKQLTTLEGEYYRADTLDLTFDPAEQDLEQTIRALCDEAERKVRDGAVLLVLSDRAISTSRLPVPAPMAVGAIQTRLVEK
SLRCDANIIVETASARDPHHFAVLLGFGATAVYPYLAYETLAKLVDTQAIDKKYREVMLNYRNGINKGLYKIMSKMGIST
IASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDIQQDLQNLSKRAWLKRKPLEQGGLLKFVHDGEYHAYNPDVVS
TLQTAVHSGKYSDYQTYAKLVNERPVAMLRDLLAITPKGTPIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMN
SLGGFSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKYA
GCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQD
EKLRRDHYHGLPERVVNYFQFIARETREIMAQLGVSQLVDLIGRTEFLTELDGISAKQNKLDLSPLLQTATPHPGKALYC
TESSNPPFDQGLMNKDLLAQAQPHIEARQSKAFYFDIRNTDRSVGATLSGAIATVHGDQGMAADPIKAYFSGTAGQSFGV
WNAGGVELTLTGDANDYVGKGMAGGRIAVRPPIGSAFRSHEASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVE
GIGDNGCEYMTGGIVCVMGKTGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQATGS
SRAEEILANWPEWAPKFALVKPKSSDVKALLGHRSRTAAELRVQAQ

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1487, Percent_Identity=87.9623402824479, Blast_Score=2707, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1525, Percent_Identity=41.6393442622951, Blast_Score=1085, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1530, Percent_Identity=42.875816993464, Blast_Score=1160, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1497, Percent_Identity=43.2865731462926, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1497, Percent_Identity=43.2865731462926, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=369, Percent_Identity=45.2574525745258, Blast_Score=296, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24665543, Length=369, Percent_Identity=45.2574525745258, Blast_Score=296, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 163421; Mature: 163421

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDKSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDRFFRMVAEERSWRLAKNYAVGMMFLSQNEEEARASRRIVEEELQNETLSVVGWREVP
CHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TNPDVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIARRRIEKRVQDDSFYVCSFSN
CCHHHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
LVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCE
NTITGNRQWARARTYKFQTPLIPDLQTAAPFVNETGSDSSSLDNMLELLLAGGMDLIRAM
EEEECCCCHHHHHCEEECCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
RLLVPPAWQNNPDMDTDLRAFFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARY
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCE
VITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGRILHSAETDDDLKSRHP
EEECCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCHHHHHCCC
YKEWMEKNVKRLVPFEDLPADQVGSRELDDSQLETYQKQFGYSSEELDQVIRVLGEIGQE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHH
ATGSMGDDTPFAVLSSRPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFC
HCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EAEGQAHRLSFKSPILLYSDFKQLTTLEGEYYRADTLDLTFDPAEQDLEQTIRALCDEAE
ECCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEECEEEEEECCHHHHHHHHHHHHHHHHH
RKVRDGAVLLVLSDRAISTSRLPVPAPMAVGAIQTRLVEKSLRCDANIIVETASARDPHH
HHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCE
FAVLLGFGATAVYPYLAYETLAKLVDTQAIDKKYREVMLNYRNGINKGLYKIMSKMGIST
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
IASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDIQQDLQNLSKRAWLKRKPLEQG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GLLKFVHDGEYHAYNPDVVSTLQTAVHSGKYSDYQTYAKLVNERPVAMLRDLLAITPKGT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC
PIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMNSLGGFSNSGEGGEDPARYGT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
NKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
HHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCC
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLI
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVK
EEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
AAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRRDHYHGLPERVVNYFQ
HHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
FIARETREIMAQLGVSQLVDLIGRTEFLTELDGISAKQNKLDLSPLLQTATPHPGKALYC
HHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEE
TESSNPPFDQGLMNKDLLAQAQPHIEARQSKAFYFDIRNTDRSVGATLSGAIATVHGDQG
ECCCCCCHHHCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCHHCCCCCCCEEEEECCCC
MAADPIKAYFSGTAGQSFGVWNAGGVELTLTGDANDYVGKGMAGGRIAVRPPIGSAFRSH
CCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHCC
EASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVEGIGDNGCEYMTGGIVCVMGK
CCCEECCEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCEEEEECC
TGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQATGS
CCCCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRAEEILANWPEWAPKFALVKPKSSDVKALLGHRSRTAAELRVQAQ
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure
MLYDKSQERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDRFFRMVAEERSWRLAKNYAVGMMFLSQNEEEARASRRIVEEELQNETLSVVGWREVP
CHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TNPDVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIARRRIEKRVQDDSFYVCSFSN
CCHHHHHHHHHHCCCCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
LVTIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGEI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCE
NTITGNRQWARARTYKFQTPLIPDLQTAAPFVNETGSDSSSLDNMLELLLAGGMDLIRAM
EEEECCCCHHHHHCEEECCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHCCHHHHHHH
RLLVPPAWQNNPDMDTDLRAFFDFNSMHMEPWDGPAGIVMSDGRYAACNLDRNGLRPARY
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCCCCCCE
VITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGRILHSAETDDDLKSRHP
EEECCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEECCCCCEEECCCCCHHHHHCCC
YKEWMEKNVKRLVPFEDLPADQVGSRELDDSQLETYQKQFGYSSEELDQVIRVLGEIGQE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHH
ATGSMGDDTPFAVLSSRPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFC
HCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEE
EAEGQAHRLSFKSPILLYSDFKQLTTLEGEYYRADTLDLTFDPAEQDLEQTIRALCDEAE
ECCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEECEEEEEECCHHHHHHHHHHHHHHHHH
RKVRDGAVLLVLSDRAISTSRLPVPAPMAVGAIQTRLVEKSLRCDANIIVETASARDPHH
HHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCE
FAVLLGFGATAVYPYLAYETLAKLVDTQAIDKKYREVMLNYRNGINKGLYKIMSKMGIST
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHH
IASYRCAKLFEAVGLHRDLSDLCFQGVVSRIGGASFSDIQQDLQNLSKRAWLKRKPLEQG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GLLKFVHDGEYHAYNPDVVSTLQTAVHSGKYSDYQTYAKLVNERPVAMLRDLLAITPKGT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC
PIPVDQVEPAESLFKRFDTAAMSIGALSPEAHESLAIAMNSLGGFSNSGEGGEDPARYGT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCC
NKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVP
HHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCC
GVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLI
CEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
TIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIVK
EEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
AAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRRDHYHGLPERVVNYFQ
HHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
FIARETREIMAQLGVSQLVDLIGRTEFLTELDGISAKQNKLDLSPLLQTATPHPGKALYC
HHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEE
TESSNPPFDQGLMNKDLLAQAQPHIEARQSKAFYFDIRNTDRSVGATLSGAIATVHGDQG
ECCCCCCHHHCCCCHHHHHHCCCCHHHHCCCEEEEEECCCCCHHCCCCCCCEEEEECCCC
MAADPIKAYFSGTAGQSFGVWNAGGVELTLTGDANDYVGKGMAGGRIAVRPPIGSAFRSH
CCCCHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHCCCCCCCEEEEECCCCHHHHCC
EASIIGNTCLYGATGGKLFAAGRAGERFAVRNSGAITVVEGIGDNGCEYMTGGIVCVMGK
CCCEECCEEEECCCCCCEEEECCCCCEEEEECCCCEEEEECCCCCCCCEECCCEEEEECC
TGINFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVEQLAIHEEHLRGLITEHVQATGS
CCCCCCCCCCCCEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRAEEILANWPEWAPKFALVKPKSSDVKALLGHRSRTAAELRVQAQ
HHHHHHHHCCCCCCCCEEEECCCCCCHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 1673677; 2643092 [H]