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The map label for this gene is arcB [H]

Identifier: 157372575

GI number: 157372575

Start: 4809283

End: 4811622

Strand: Reverse

Name: arcB [H]

Synonym: Spro_4342

Alternate gene names: 157372575

Gene position: 4811622-4809283 (Counterclockwise)

Preceding gene: 157372576

Following gene: 157372574

Centisome position: 88.31

GC content: 55.56

Gene sequence:

>2340_bases
ATGAAGCAAATCCGGGTGTTAGCCCAGTACTACGTTGATTTAATGGTAAAACTGGGGCTGGTGCGCTTTTCGCTGCTGCT
GGCATCGGCGCTGGTGGTGCTGGCGATGGTGGTACAGATGGCGGTCACCATGCTGCTGCGCGGGGAAGTAGAAAGCATAG
ACGTGGTGCGTTCCATCTTCTTCGGCCTGCTGATTACGCCATGGGCGGTCTACTTTCTGTCGGTGGTGGTCGAACAGCTT
GAGGAGTCGCGCCAGCGCCTGACGCGGCTGGTGGATAAGCTCGAAGAGATGCGCCACCGCGACCTGGAGCTGAACCAACA
GCTTAAGGACAACATCAGCCAACTGAATCAGGAAATTGCCGACCGTATCAAGGCGGAAGAAGAACGTCAGCAGGTGATGG
ACAAACTGACGGGAGAGATGGAGCAGCGTGAACTGGCGCAGATCGAACTGGGCCAGCAGTCGGCACTGCTGCGCTCCTTC
CTCGACGCTTCACCGGATCTGGTCTATTACCGCAACGAAGACAAAGAGTTCTCTGGCTGTAACCGGGCGATGGAACTGCT
GACCGGCAAAAGCGAAAAGCAGCTGATCGGTCTGACGCCTTTTGACGTCTACGGTGAGGAAATTGCCGAGAAGGTAATCG
AAACCGACGAGAAAGTGTTCCGTCACAACGTCTCACTGACCTACGAACAGTGGCTGGTTTACCCGGATGGTCGCAAGGCC
TGTTTTGAGCTGCGCAAGGTGCCGTTTTACGACCGCGTGGGCAAACGCCACGGCCTTATGGGCTTTGGCCGCGATATAAC
CGAACGTAAGCGCTATCAGGACGCGCTGGAGAATGCCAGCAGGGACAAGACTACCTTCATCTCAACGATCAGCCACGAGC
TTCGTACGCCGCTTAACGGCATCGTCGGCCTGAGTCGCATTCTGCTCGACACCGAGTTAAACGACGAACAGCTGAAATAC
CTCAAAACCATCCATGTCAGCGCCATCACGCTGGGTAATATCTTCAATGACATTATCGAGATGGACAAACTCGAGCGCCG
TAAAGTGCAGCTCGACAATCAACCGGTGGACTTTACCGGCTTCCTGGCCGATTTGGAAAACCTCTCCGGCCTGCTGGTGC
AGCCGAAAGGGCTGCAGTTTGTGATGGAGCCGCAACAACCGCTGCCGCAACAAATCATCGCCGATGGTACCCGCCTGCGG
CAGATCCTGTGGAACCTGATCGGCAACGCGGTGAAGTTTACCCCGCAGGGGCAAATCGTGGTGCGGGTGCGGCGTGAAGA
GCAGGATCGGCTGGTGTTTGAAGTGGAAGACTCCGGCATGGGCATTCCGCAGGATGAACAGGACAAGATCTTCGCCATGT
ATTATCAGGTGAAGGATCAGCACGGCGGCCGTCCGGCGACCGGTACCGGTATTGGGCTGGCGGTTTCCAAGCGGCTGGCG
CAGAGCATGGGCGGCGATATCACCGTCAGCAGCGTCCAGGGGCAGGGTTCTTGCTTCACCTTATCCATCAAGGCACCGGC
GGTGCAGGAAGTGGAAAGTGAAACCGCAGTTGAAGAGGAACTGCCATTGCCGGCGTTGCATATTCTGCTGGTGGAAGATA
TTGAGCTGAATGTGATTGTGGCGCGTTCGGTACTGGAAAAACTGGGTAACAGCGTTGAAGTGGCGATGAACGGCCAGGAT
GCGCTGGCCATGTTTGATCCGGACGAGTTCGATCTGGTGCTGTTGGACATCCAGTTGCCGGATATGACCGGGCTGGATAT
CGCCCGGATACTGCGTGAACGCTATGCCGGGCAGGCGTTGCCGCCGCTGGTTGCGCTGACTGCCAACGTACTGAAAGACA
AAAAAGAGTACCTCGACGCGGGAATGGACGATGTGCTGAGCAAGCCGCTGTCGGTACCGGCGCTGACCAAAGTGATTAAA
CATTACTGGGATCATCAACCCTCTCACACCACGAAGAAAACGGAGCAAAAGACGATGAAGATTAATGAGTCTTTACTGGA
TACCACCATGCTGGAACAGTATATGGACCTGGTGGGGCCGCAGTTGATTCATCAAAGCCTGGAGATGTTTGAGCAGATGA
TGCCGGGTTATCTGGCAGTGCTGGATTCCAACATGACGGCGCGCGACCAGAAAGGCATCACGGAAGAGGGGCATAAAATC
AAAGGTGCCGCCGGCTCGGTTGGCCTGCGTCATTTGCAACAAATTGCGCAGCAAATTCAAACTCCGACGCTGCCGGCATG
GTGGGATAACGTGCAAGATTGGGTTGATGAGTTGAAGCTGGAATGGCGCAACGATGTGCAGGTACTGCGTGAGTGGGTAG
CGGAAGCTGAAAAAAAATGA

Upstream 100 bases:

>100_bases
TGTTTTGATTTGCAATCTTTCCCACACTTCGGCGTTTGCTTTCTTATCTCACCGGGGTTTTACGGTATGATTTACAAGAT
TCTGTCTGATGGGAGCGGCT

Downstream 100 bases:

>100_bases
CCCCGACCTAGGCCGGGGTGCGCGAATATTGCGCCAACACCAGGGAAATTGTGAACCTGCGTATTGGTTTTAATGTTCTG
GTCGAGCAGGTTGTAGAGAA

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVVLAMVVQMAVTMLLRGEVESIDVVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLTRLVDKLEEMRHRDLELNQQLKDNISQLNQEIADRIKAEEERQQVMDKLTGEMEQRELAQIELGQQSALLRSF
LDASPDLVYYRNEDKEFSGCNRAMELLTGKSEKQLIGLTPFDVYGEEIAEKVIETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELNDEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFLADLENLSGLLVQPKGLQFVMEPQQPLPQQIIADGTRLR
QILWNLIGNAVKFTPQGQIVVRVRREEQDRLVFEVEDSGMGIPQDEQDKIFAMYYQVKDQHGGRPATGTGIGLAVSKRLA
QSMGGDITVSSVQGQGSCFTLSIKAPAVQEVESETAVEEELPLPALHILLVEDIELNVIVARSVLEKLGNSVEVAMNGQD
ALAMFDPDEFDLVLLDIQLPDMTGLDIARILRERYAGQALPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTKVIK
HYWDHQPSHTTKKTEQKTMKINESLLDTTMLEQYMDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEGHKI
KGAAGSVGLRHLQQIAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWVAEAEKK

Sequences:

>Translated_779_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVVLAMVVQMAVTMLLRGEVESIDVVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLTRLVDKLEEMRHRDLELNQQLKDNISQLNQEIADRIKAEEERQQVMDKLTGEMEQRELAQIELGQQSALLRSF
LDASPDLVYYRNEDKEFSGCNRAMELLTGKSEKQLIGLTPFDVYGEEIAEKVIETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELNDEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFLADLENLSGLLVQPKGLQFVMEPQQPLPQQIIADGTRLR
QILWNLIGNAVKFTPQGQIVVRVRREEQDRLVFEVEDSGMGIPQDEQDKIFAMYYQVKDQHGGRPATGTGIGLAVSKRLA
QSMGGDITVSSVQGQGSCFTLSIKAPAVQEVESETAVEEELPLPALHILLVEDIELNVIVARSVLEKLGNSVEVAMNGQD
ALAMFDPDEFDLVLLDIQLPDMTGLDIARILRERYAGQALPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTKVIK
HYWDHQPSHTTKKTEQKTMKINESLLDTTMLEQYMDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEGHKI
KGAAGSVGLRHLQQIAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWVAEAEKK
>Mature_779_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVVLAMVVQMAVTMLLRGEVESIDVVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLTRLVDKLEEMRHRDLELNQQLKDNISQLNQEIADRIKAEEERQQVMDKLTGEMEQRELAQIELGQQSALLRSF
LDASPDLVYYRNEDKEFSGCNRAMELLTGKSEKQLIGLTPFDVYGEEIAEKVIETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELNDEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFLADLENLSGLLVQPKGLQFVMEPQQPLPQQIIADGTRLR
QILWNLIGNAVKFTPQGQIVVRVRREEQDRLVFEVEDSGMGIPQDEQDKIFAMYYQVKDQHGGRPATGTGIGLAVSKRLA
QSMGGDITVSSVQGQGSCFTLSIKAPAVQEVESETAVEEELPLPALHILLVEDIELNVIVARSVLEKLGNSVEVAMNGQD
ALAMFDPDEFDLVLLDIQLPDMTGLDIARILRERYAGQALPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTKVIK
HYWDHQPSHTTKKTEQKTMKINESLLDTTMLEQYMDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEGHKI
KGAAGSVGLRHLQQIAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWVAEAEKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=779, Percent_Identity=77.4069319640565, Blast_Score=1206, Evalue=0.0,
Organism=Escherichia coli, GI87081816, Length=485, Percent_Identity=28.8659793814433, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1788713, Length=630, Percent_Identity=27.4603174603175, Blast_Score=182, Evalue=8e-47,
Organism=Escherichia coli, GI1789149, Length=478, Percent_Identity=29.4979079497908, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=34.8, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788549, Length=409, Percent_Identity=26.4058679706601, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786600, Length=357, Percent_Identity=26.6106442577031, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=30.2325581395349, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=24.7863247863248, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=22.9357798165138, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=24.8945147679325, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790551, Length=215, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790300, Length=238, Percent_Identity=26.0504201680672, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=24, Blast_Score=63, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=119, Percent_Identity=31.9327731092437, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88509; Mature: 88509

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVVLAMVVQMAVTMLLRGEVESIDVVRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLTRLVDKLEEMRHRDLELNQQLKDNISQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DRIKAEEERQQVMDKLTGEMEQRELAQIELGQQSALLRSFLDASPDLVYYRNEDKEFSGC
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLIGLTPFDVYGEEIAEKVIETDEKVFRHNVSLTYEQWLVYPDGRKA
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEECCCHHH
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELNDEQLKYLKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FLADLENLSGLLVQPKGLQFVMEPQQPLPQQIIADGTRLRQILWNLIGNAVKFTPQGQIV
HHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHHHCCCEEECCCCCEE
VRVRREEQDRLVFEVEDSGMGIPQDEQDKIFAMYYQVKDQHGGRPATGTGIGLAVSKRLA
EEEECCCCCCEEEEECCCCCCCCCCCCCCEEEHEEEHHHCCCCCCCCCCCHHHHHHHHHH
QSMGGDITVSSVQGQGSCFTLSIKAPAVQEVESETAVEEELPLPALHILLVEDIELNVIV
HHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHH
ARSVLEKLGNSVEVAMNGQDALAMFDPDEFDLVLLDIQLPDMTGLDIARILRERYAGQAL
HHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTKVIKHYWDHQPSHTTKKTEQKTMK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
INESLLDTTMLEQYMDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEGHKI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEEHHCCCCCCHHCCCCCCCCCEE
KGAAGSVGLRHLQQIAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWVAEAEKK
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVVLAMVVQMAVTMLLRGEVESIDVVRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLTRLVDKLEEMRHRDLELNQQLKDNISQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
DRIKAEEERQQVMDKLTGEMEQRELAQIELGQQSALLRSFLDASPDLVYYRNEDKEFSGC
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLIGLTPFDVYGEEIAEKVIETDEKVFRHNVSLTYEQWLVYPDGRKA
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEECCCHHH
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELNDEQLKYLKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FLADLENLSGLLVQPKGLQFVMEPQQPLPQQIIADGTRLRQILWNLIGNAVKFTPQGQIV
HHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHHHCCCEEECCCCCEE
VRVRREEQDRLVFEVEDSGMGIPQDEQDKIFAMYYQVKDQHGGRPATGTGIGLAVSKRLA
EEEECCCCCCEEEEECCCCCCCCCCCCCCEEEHEEEHHHCCCCCCCCCCCHHHHHHHHHH
QSMGGDITVSSVQGQGSCFTLSIKAPAVQEVESETAVEEELPLPALHILLVEDIELNVIV
HHCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHH
ARSVLEKLGNSVEVAMNGQDALAMFDPDEFDLVLLDIQLPDMTGLDIARILRERYAGQAL
HHHHHHHCCCCEEEEECCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTKVIKHYWDHQPSHTTKKTEQKTMK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
INESLLDTTMLEQYMDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEGHKI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEEHHCCCCCCHHCCCCCCCCCEE
KGAAGSVGLRHLQQIAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWVAEAEKK
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]