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The map label for this gene is exuT [H]

Identifier: 157372555

GI number: 157372555

Start: 4793315

End: 4794613

Strand: Direct

Name: exuT [H]

Synonym: Spro_4322

Alternate gene names: 157372555

Gene position: 4793315-4794613 (Clockwise)

Preceding gene: 157372552

Following gene: 157372556

Centisome position: 87.97

GC content: 58.81

Gene sequence:

>1299_bases
ATGCGTAAAATTAAAGGGTTACGCTGGTACATGATAGGGCTGGTGACCATCGGCACCGTGCTGGGCTACCTGACCCGCAA
TGCCATGGCCGTGGCGGCACCGACGCTGGAAGGCACCTTACATATCACCACGCAGCAGTACTCGTACATTGTCGCGGCCT
ATTCTGCCTGCTACACCCTGATGCAGCCGGTGGCGGGATACGTGCTGGACGTACTGGGTACCAAGGTGGGTTACGCCATG
TTCGCCATTCTGTGGGCGCTGTTTTGTATGGGCACCGCACTCGCCAACAGTTGGGGCGGTCTGGCACTGGCGCGCGGCGC
CGTTGGCATGGCAGAGGCGGCGATGATCCCCGCCGGGCTGAAGGCCAGCAGCGAGTGGTTCCCGGCCAAAGAACGTTCGA
TAGCCGTTGGCTACTTCAACGTCGGCTCGTCAATCGGCGGCATGCTCGCTCCACCGCTGGTGGTCTGGGCCATAGTGGCA
CACAGTTGGGAAATGGCGTTTATCATCACCGGCGTGCTAAGCCTGATCTGGGCCATCTGCTGGCTGATCTTCTATAAGCA
CCCGAAAGACCAGAAGAAACTCAGCAGTGAGGAACGCGAGTACATTCTGGAGGGCCAGGAAGCGCAGCACCAAACCGACA
ACGCCAAGAAAATGTCCGCCTGGCAGATTGTGCGCAACCGCCAGTTCTGGGGCATAGCGCTGCCGCGTTTTCTGGCAGAG
CCTGCCTGGGGCACCTTCAACGCGTGGATCCCGTTATTCATGTTCAAAGCCTATGGTTTTAACCTGAAAGAGATCGCCAT
GTTCGCCTGGATGCCGATGCTGTTCGCCGATCTCGGCTGCATCGTTGGTGGCTACCTGCCGCCGTTTTTCCAAAAGCACT
TTAAGGTGAACCTGATCGTTTCACGCAAACTGGTGGTCACTATGGGGGCCGTGCTAATGATTGGCCCTGGCATGATCGGT
TTGTTTACCAGCCCTTATGCGGCTATCGCGCTACTGTGCGTCGGTGGTTTTGCCCATCAGGCGCTGTCTGGCGCGCTGAT
TACCCTCTCATCTGACGTGTTTGGTCGCAACGAAGTGGCCACCGCCAACGGCCTGACCGGCATGGCAGCCTGGACCGCCA
GCACAATGTTTGCCCTGGTGGTCGGCGCATTGGCCGATACTCTGGGTTTTAGCCCACTGTTCGCCGCGCTGTCGGTATTC
GATATTCTCGGTGCCATCGCCATCTGGACCATCCTGCAAAATCGGCCGGCCTCACAGCCGCAGGAAGATCCGCTGCAACC
GGCCTCGGCTCGCAGTTAA

Upstream 100 bases:

>100_bases
TCGGTGACGGACAGACCGGCGCAGAACAACGAAAAGGGGGAGCCCCTTAAACTCTGCCGCCATCTCGGCGTCACCTATTG
AAGACTGGGAGATATTTTGG

Downstream 100 bases:

>100_bases
CCCCATCGCCCGGCCAGCGTGCCGGGCGCGCCCTCCCGGCCACTGGTAGCTCAGCAGGATAAGTGGTATAACAAATCCAT
GGTTACGCGCCCCTCCCTAC

Product: d-galactonate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRKIKGLRWYMIGLVTIGTVLGYLTRNAMAVAAPTLEGTLHITTQQYSYIVAAYSACYTLMQPVAGYVLDVLGTKVGYAM
FAILWALFCMGTALANSWGGLALARGAVGMAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGGMLAPPLVVWAIVA
HSWEMAFIITGVLSLIWAICWLIFYKHPKDQKKLSSEEREYILEGQEAQHQTDNAKKMSAWQIVRNRQFWGIALPRFLAE
PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPFFQKHFKVNLIVSRKLVVTMGAVLMIGPGMIG
LFTSPYAAIALLCVGGFAHQALSGALITLSSDVFGRNEVATANGLTGMAAWTASTMFALVVGALADTLGFSPLFAALSVF
DILGAIAIWTILQNRPASQPQEDPLQPASARS

Sequences:

>Translated_432_residues
MRKIKGLRWYMIGLVTIGTVLGYLTRNAMAVAAPTLEGTLHITTQQYSYIVAAYSACYTLMQPVAGYVLDVLGTKVGYAM
FAILWALFCMGTALANSWGGLALARGAVGMAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGGMLAPPLVVWAIVA
HSWEMAFIITGVLSLIWAICWLIFYKHPKDQKKLSSEEREYILEGQEAQHQTDNAKKMSAWQIVRNRQFWGIALPRFLAE
PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPFFQKHFKVNLIVSRKLVVTMGAVLMIGPGMIG
LFTSPYAAIALLCVGGFAHQALSGALITLSSDVFGRNEVATANGLTGMAAWTASTMFALVVGALADTLGFSPLFAALSVF
DILGAIAIWTILQNRPASQPQEDPLQPASARS
>Mature_432_residues
MRKIKGLRWYMIGLVTIGTVLGYLTRNAMAVAAPTLEGTLHITTQQYSYIVAAYSACYTLMQPVAGYVLDVLGTKVGYAM
FAILWALFCMGTALANSWGGLALARGAVGMAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGGMLAPPLVVWAIVA
HSWEMAFIITGVLSLIWAICWLIFYKHPKDQKKLSSEEREYILEGQEAQHQTDNAKKMSAWQIVRNRQFWGIALPRFLAE
PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPFFQKHFKVNLIVSRKLVVTMGAVLMIGPGMIG
LFTSPYAAIALLCVGGFAHQALSGALITLSSDVFGRNEVATANGLTGMAAWTASTMFALVVGALADTLGFSPLFAALSVF
DILGAIAIWTILQNRPASQPQEDPLQPASARS

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=339, Percent_Identity=23.3038348082596, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI148743791, Length=254, Percent_Identity=24.0157480314961, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154800443, Length=368, Percent_Identity=23.3695652173913, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367193, Length=429, Percent_Identity=82.7505827505828, Blast_Score=712, Evalue=0.0,
Organism=Escherichia coli, GI87082320, Length=409, Percent_Identity=25.6723716381418, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI2367379, Length=437, Percent_Identity=25.1716247139588, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1789515, Length=405, Percent_Identity=24.9382716049383, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789152, Length=327, Percent_Identity=22.3241590214067, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082071, Length=424, Percent_Identity=21.6981132075472, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540458, Length=313, Percent_Identity=23.0031948881789, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=245, Percent_Identity=25.3061224489796, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=338, Percent_Identity=21.8934911242604, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533554, Length=338, Percent_Identity=21.8934911242604, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=358, Percent_Identity=21.5083798882682, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24580790, Length=291, Percent_Identity=26.1168384879725, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639764, Length=368, Percent_Identity=22.2826086956522, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641682, Length=183, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45550460, Length=361, Percent_Identity=24.3767313019391, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24655255, Length=361, Percent_Identity=24.3767313019391, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129235, Length=355, Percent_Identity=24.7887323943662, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24658696, Length=276, Percent_Identity=24.6376811594203, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46884; Mature: 46884

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIKGLRWYMIGLVTIGTVLGYLTRNAMAVAAPTLEGTLHITTQQYSYIVAAYSACYTL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHH
MQPVAGYVLDVLGTKVGYAMFAILWALFCMGTALANSWGGLALARGAVGMAEAAMIPAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCC
KASSEWFPAKERSIAVGYFNVGSSIGGMLAPPLVVWAIVAHSWEMAFIITGVLSLIWAIC
CCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
WLIFYKHPKDQKKLSSEEREYILEGQEAQHQTDNAKKMSAWQIVRNRQFWGIALPRFLAE
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPFFQKHFKVNLIV
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEEE
SRKLVVTMGAVLMIGPGMIGLFTSPYAAIALLCVGGFAHQALSGALITLSSDVFGRNEVA
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
TANGLTGMAAWTASTMFALVVGALADTLGFSPLFAALSVFDILGAIAIWTILQNRPASQP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEDPLQPASARS
CCCCCCCCCCCC
>Mature Secondary Structure
MRKIKGLRWYMIGLVTIGTVLGYLTRNAMAVAAPTLEGTLHITTQQYSYIVAAYSACYTL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHHHHHHHHHHHHHHH
MQPVAGYVLDVLGTKVGYAMFAILWALFCMGTALANSWGGLALARGAVGMAEAAMIPAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHCCCCC
KASSEWFPAKERSIAVGYFNVGSSIGGMLAPPLVVWAIVAHSWEMAFIITGVLSLIWAIC
CCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
WLIFYKHPKDQKKLSSEEREYILEGQEAQHQTDNAKKMSAWQIVRNRQFWGIALPRFLAE
HHHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCC
PAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPMLFADLGCIVGGYLPPFFQKHFKVNLIV
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEEEEE
SRKLVVTMGAVLMIGPGMIGLFTSPYAAIALLCVGGFAHQALSGALITLSSDVFGRNEVA
HHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
TANGLTGMAAWTASTMFALVVGALADTLGFSPLFAALSVFDILGAIAIWTILQNRPASQP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
QEDPLQPASARS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]