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The map label for this gene is xapB [H]

Identifier: 157372487

GI number: 157372487

Start: 4716427

End: 4717686

Strand: Reverse

Name: xapB [H]

Synonym: Spro_4254

Alternate gene names: 157372487

Gene position: 4717686-4716427 (Counterclockwise)

Preceding gene: 157372488

Following gene: 157372486

Centisome position: 86.58

GC content: 53.1

Gene sequence:

>1260_bases
ATGGCAATAAAAACGCGACTGAAGGTGATGGTTTTTCTGCAGTTCTTTATCTGGGGTGCCTGGCTGGTTACGCTGGGATC
TTACATGATTAACACCCTGCATTTCAGTGGGATGCAGGTGGGTATGGTCTACAGCGCCAAAGGCATCGCGGCGCTGATTA
TGCCGGGATTGGCAGGCATTCTTGCCGATCGCTGGATCAAGGTCAACTACCTGTACGCGCTGTGTCATTTGTTTGGTGCG
TTGGCACTGTACTGTGCCGCCCAGGTTGAGCAACCTATGGTGATGTTCTGGGTGATGCTGTTCAACGCCATGGTGTATAT
GCCCACGATTTCGCTCTCCAACGCCATTTCTTATTTCTGCCTGGAGAAGCACGGTTACGATACGGTGAAAGATTTTCCGC
CGGTACGGGTGTACGGCACCGTCGGCTTTATCGTAGCGATGTGGTTGATCGGTTTTAGCAGAATTGAACTCAGCAATTTG
CAACTCTATCTGGCCTCCGGGGTGTCGTTGTTGTTGGCGGGTTATTCGCTGACGCTGCCGAATTGCCCGACCAGCAAAGT
GGAAAAATCGAAAAGCTGGTTCAGCGTTTTGGGGCTGGACGCGCTGGTGCTATTCCGCCAGCGGCGCATGGCGCTGTTTT
TCCTGTTTGCCATGTTATTGGGTGCCGCACTGCAGGTCACCAACACCTTCGGCAATCCCTTCCTGCACGATTTCGCCAAT
AATCCGTTGTATCAGGACAGCATAAGCGTCAGGTACCCCGCGGTGCTGTTGTCGCTGTCACAAATCTCCGAGGTGTTCTT
TATCCTCACCATTCCGTTCTTCTTGCGTCGATATGGCATCAAACAGGTGATGTTGATCAGCATGGCGGCCTGGACCCTGC
GTTTCCTGTTCCTGGCCTATGGCACCCCGGCGGGTTTCGGTTTTGTGCTGCTGCTGCTTTCGATGATCGTCTACGGTTGC
GCCTTTGATTTCTTTAATATCTCAGGGGCTATTTTCGTTGAGAAAGAGGCCGATCACCGCATTCGTGCCAGTGCACAAGG
GTTGTTTATGACCATGGTGAACGGTATCGGCGCTTATCTGGGGGCGATTGCCAGCGGTGAGGTGGTGGACTTCTTCACCC
ACAACGGCGTCAAGGACTGGCAAAGTATCTGGCTGATCTTCGCGTTATATACGCTGGTATTGGGAGTGATTTTCGCACTG
ACCTTCAACTACCAGCATCGGCCGGAGGAGCTGTCTGGGGCGGCGCAACGGGCACATTAA

Upstream 100 bases:

>100_bases
ATTCTTCAAAACGCGGTAATGCCGTAAACCTCCCGACGGCAGGGTGCAGGGGCCCTGTCGTGCGAATCATCGTTTTAATC
AGAATAATAAGGTGATGGTG

Downstream 100 bases:

>100_bases
AACCCTATGGGCGCATCTCGATTTGCGCCCATTTTACTTTATGGCCTCTCGCCTTGCCGCTGCGCTATTTCCCAGTTTTA
CCCCGGCAGGTGATATTTCT

Product: nucleoside transporter

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MAIKTRLKVMVFLQFFIWGAWLVTLGSYMINTLHFSGMQVGMVYSAKGIAALIMPGLAGILADRWIKVNYLYALCHLFGA
LALYCAAQVEQPMVMFWVMLFNAMVYMPTISLSNAISYFCLEKHGYDTVKDFPPVRVYGTVGFIVAMWLIGFSRIELSNL
QLYLASGVSLLLAGYSLTLPNCPTSKVEKSKSWFSVLGLDALVLFRQRRMALFFLFAMLLGAALQVTNTFGNPFLHDFAN
NPLYQDSISVRYPAVLLSLSQISEVFFILTIPFFLRRYGIKQVMLISMAAWTLRFLFLAYGTPAGFGFVLLLLSMIVYGC
AFDFFNISGAIFVEKEADHRIRASAQGLFMTMVNGIGAYLGAIASGEVVDFFTHNGVKDWQSIWLIFALYTLVLGVIFAL
TFNYQHRPEELSGAAQRAH

Sequences:

>Translated_419_residues
MAIKTRLKVMVFLQFFIWGAWLVTLGSYMINTLHFSGMQVGMVYSAKGIAALIMPGLAGILADRWIKVNYLYALCHLFGA
LALYCAAQVEQPMVMFWVMLFNAMVYMPTISLSNAISYFCLEKHGYDTVKDFPPVRVYGTVGFIVAMWLIGFSRIELSNL
QLYLASGVSLLLAGYSLTLPNCPTSKVEKSKSWFSVLGLDALVLFRQRRMALFFLFAMLLGAALQVTNTFGNPFLHDFAN
NPLYQDSISVRYPAVLLSLSQISEVFFILTIPFFLRRYGIKQVMLISMAAWTLRFLFLAYGTPAGFGFVLLLLSMIVYGC
AFDFFNISGAIFVEKEADHRIRASAQGLFMTMVNGIGAYLGAIASGEVVDFFTHNGVKDWQSIWLIFALYTLVLGVIFAL
TFNYQHRPEELSGAAQRAH
>Mature_418_residues
AIKTRLKVMVFLQFFIWGAWLVTLGSYMINTLHFSGMQVGMVYSAKGIAALIMPGLAGILADRWIKVNYLYALCHLFGAL
ALYCAAQVEQPMVMFWVMLFNAMVYMPTISLSNAISYFCLEKHGYDTVKDFPPVRVYGTVGFIVAMWLIGFSRIELSNLQ
LYLASGVSLLLAGYSLTLPNCPTSKVEKSKSWFSVLGLDALVLFRQRRMALFFLFAMLLGAALQVTNTFGNPFLHDFANN
PLYQDSISVRYPAVLLSLSQISEVFFILTIPFFLRRYGIKQVMLISMAAWTLRFLFLAYGTPAGFGFVLLLLSMIVYGCA
FDFFNISGAIFVEKEADHRIRASAQGLFMTMVNGIGAYLGAIASGEVVDFFTHNGVKDWQSIWLIFALYTLVLGVIFALT
FNYQHRPEELSGAAQRAH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=415, Percent_Identity=65.5421686746988, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI87082192, Length=406, Percent_Identity=55.9113300492611, Blast_Score=476, Evalue=1e-136,
Organism=Escherichia coli, GI1788415, Length=417, Percent_Identity=31.4148681055156, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46965; Mature: 46834

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKTRLKVMVFLQFFIWGAWLVTLGSYMINTLHFSGMQVGMVYSAKGIAALIMPGLAGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHH
LADRWIKVNYLYALCHLFGALALYCAAQVEQPMVMFWVMLFNAMVYMPTISLSNAISYFC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LEKHGYDTVKDFPPVRVYGTVGFIVAMWLIGFSRIELSNLQLYLASGVSLLLAGYSLTLP
HHCCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHEEHHHHHHHHHCCHHHHHHCCEEECC
NCPTSKVEKSKSWFSVLGLDALVLFRQRRMALFFLFAMLLGAALQVTNTFGNPFLHDFAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
NPLYQDSISVRYPAVLLSLSQISEVFFILTIPFFLRRYGIKQVMLISMAAWTLRFLFLAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GTPAGFGFVLLLLSMIVYGCAFDFFNISGAIFVEKEADHRIRASAQGLFMTMVNGIGAYL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GAIASGEVVDFFTHNGVKDWQSIWLIFALYTLVLGVIFALTFNYQHRPEELSGAAQRAH
HHHCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCC
>Mature Secondary Structure 
AIKTRLKVMVFLQFFIWGAWLVTLGSYMINTLHFSGMQVGMVYSAKGIAALIMPGLAGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHH
LADRWIKVNYLYALCHLFGALALYCAAQVEQPMVMFWVMLFNAMVYMPTISLSNAISYFC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LEKHGYDTVKDFPPVRVYGTVGFIVAMWLIGFSRIELSNLQLYLASGVSLLLAGYSLTLP
HHCCCCCCHHCCCCEEEEHHHHHHHHHHHHHHHHEEHHHHHHHHHCCHHHHHHCCEEECC
NCPTSKVEKSKSWFSVLGLDALVLFRQRRMALFFLFAMLLGAALQVTNTFGNPFLHDFAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
NPLYQDSISVRYPAVLLSLSQISEVFFILTIPFFLRRYGIKQVMLISMAAWTLRFLFLAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GTPAGFGFVLLLLSMIVYGCAFDFFNISGAIFVEKEADHRIRASAQGLFMTMVNGIGAYL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
GAIASGEVVDFFTHNGVKDWQSIWLIFALYTLVLGVIFALTFNYQHRPEELSGAAQRAH
HHHCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]