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The map label for this gene is yphC [H]

Identifier: 157372459

GI number: 157372459

Start: 4684931

End: 4685989

Strand: Reverse

Name: yphC [H]

Synonym: Spro_4226

Alternate gene names: 157372459

Gene position: 4685989-4684931 (Counterclockwise)

Preceding gene: 157372460

Following gene: 157372458

Centisome position: 86.0

GC content: 59.02

Gene sequence:

>1059_bases
ATGGGGAAAATGTTGGCGGCTTATTTACCCGGAAACGCCACGGCAGAACTGCGCGAGGTGGATATTCCGCAACCGGGCAT
TGGCCAGGTATTAATTAAAATGAAATCGTCCGGTATTTGCGGCAGCGATATTCATTATATTTATCATCAGCATCGTGGTA
CGGCGGCCGCACCGGATCAACCCTTGTACCGGGGGTTTATTAACGGTCACGAGCCTTGTGGCCAGATTGTGGCGCTGGGG
GCCGGCTGCCGCCACTTCCGCGAGAGCGATCGCGTGCTGGTGTACCATATTTCCGGCTGCGGCTTTTGCAGCAACTGCCG
GCGAGGCTATCCGATTTCCTGCACCGGCGTTGGCAAGGCCGCCTATGGCTGGCAGCGGGATGGCGGCCATGCCGACTACC
TGTTGGCGGAGGAAAAGGATTTGATTCATCTGCCGGATTCGCTCAGCTATGAAGACGGCGCTTTTATCTCCTGTGGGGTC
GGCACGGCTTATGAAGGTATCGTGCGTGGCGAGGTCTCCGGCAGCGACCACGTACTGGTCGTGGGGCTGGGCCCGGTCGG
TATGATGGCGATGATGCTGGCGAAGGGACGCGGGGCAAAAACGGTGATTGGCGTTGATGTTATCCCGGAGCGTCTGGCGA
CCGCGAAACGCCTGGGGCTGATGGATCACGGCTTCCTGAGCGGTGACGACGTGACAGAACGCATTCGCCAATTGACCGCT
GGCGGGGCCAACGTCACGCTCGACTGTTCCGGCAACGCCAAAGGGCGCCTGCTGGCGCTGCAGGCCTCTTCGGACTGGGG
AAGAGTGATCTACATTGGCGAAACCGGCAAGGTGGAATTCGAGGTCAGCGCAGACCTGATGCATCACCAGCGGCGGATCA
TCGGCTCTTGGGTCACCAGCCTGCACCACATGGAAAAATGCTGCACCGACCTGCACGACTGGAAAATGCACCCGCATCAG
GCGATCACCCACCGTTTTAAACTCGGGCAGGCTGCCGAGGCCTATGCTCTGATGGCTTCTGGCCAGTGCGGCAAAGTGGT
GATCAATTTCGCCGATTAA

Upstream 100 bases:

>100_bases
TACTGGCGGTGCTGGCCAATATTATCGTGATGCAAAAGAACTCTAAGCAATAGCCTCACATGCCACACAAATAACTGATT
AAAGCTGGAGGGAAAATAGT

Downstream 100 bases:

>100_bases
TATCCGGGGGCACTATGGCATTGTTTGATATGGATAACGGCTGTCTCTCGTTGGTGGTTTCGTCGTTGGGTGGCAGCGTG
TTGAAATTGGCCGCGCACGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGKMLAAYLPGNATAELREVDIPQPGIGQVLIKMKSSGICGSDIHYIYHQHRGTAAAPDQPLYRGFINGHEPCGQIVALG
AGCRHFRESDRVLVYHISGCGFCSNCRRGYPISCTGVGKAAYGWQRDGGHADYLLAEEKDLIHLPDSLSYEDGAFISCGV
GTAYEGIVRGEVSGSDHVLVVGLGPVGMMAMMLAKGRGAKTVIGVDVIPERLATAKRLGLMDHGFLSGDDVTERIRQLTA
GGANVTLDCSGNAKGRLLALQASSDWGRVIYIGETGKVEFEVSADLMHHQRRIIGSWVTSLHHMEKCCTDLHDWKMHPHQ
AITHRFKLGQAAEAYALMASGQCGKVVINFAD

Sequences:

>Translated_352_residues
MGKMLAAYLPGNATAELREVDIPQPGIGQVLIKMKSSGICGSDIHYIYHQHRGTAAAPDQPLYRGFINGHEPCGQIVALG
AGCRHFRESDRVLVYHISGCGFCSNCRRGYPISCTGVGKAAYGWQRDGGHADYLLAEEKDLIHLPDSLSYEDGAFISCGV
GTAYEGIVRGEVSGSDHVLVVGLGPVGMMAMMLAKGRGAKTVIGVDVIPERLATAKRLGLMDHGFLSGDDVTERIRQLTA
GGANVTLDCSGNAKGRLLALQASSDWGRVIYIGETGKVEFEVSADLMHHQRRIIGSWVTSLHHMEKCCTDLHDWKMHPHQ
AITHRFKLGQAAEAYALMASGQCGKVVINFAD
>Mature_351_residues
GKMLAAYLPGNATAELREVDIPQPGIGQVLIKMKSSGICGSDIHYIYHQHRGTAAAPDQPLYRGFINGHEPCGQIVALGA
GCRHFRESDRVLVYHISGCGFCSNCRRGYPISCTGVGKAAYGWQRDGGHADYLLAEEKDLIHLPDSLSYEDGAFISCGVG
TAYEGIVRGEVSGSDHVLVVGLGPVGMMAMMLAKGRGAKTVIGVDVIPERLATAKRLGLMDHGFLSGDDVTERIRQLTAG
GANVTLDCSGNAKGRLLALQASSDWGRVIYIGETGKVEFEVSADLMHHQRRIIGSWVTSLHHMEKCCTDLHDWKMHPHQA
ITHRFKLGQAAEAYALMASGQCGKVVINFAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=367, Percent_Identity=25.0681198910082, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI156523966, Length=368, Percent_Identity=25.5434782608696, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI156627571, Length=367, Percent_Identity=24.5231607629428, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI4501939, Length=364, Percent_Identity=25.5494505494505, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI71743840, Length=363, Percent_Identity=23.1404958677686, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI262073058, Length=363, Percent_Identity=23.1404958677686, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501929, Length=367, Percent_Identity=25.0681198910082, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=24.4565217391304, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI34577061, Length=367, Percent_Identity=24.2506811989101, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI71565154, Length=364, Percent_Identity=21.978021978022, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI87082125, Length=353, Percent_Identity=81.3031161473088, Blast_Score=602, Evalue=1e-173,
Organism=Escherichia coli, GI1790045, Length=352, Percent_Identity=28.6931818181818, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787863, Length=353, Percent_Identity=30.3116147308782, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788407, Length=336, Percent_Identity=27.0833333333333, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI226510992, Length=325, Percent_Identity=28.6153846153846, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788073, Length=266, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788075, Length=371, Percent_Identity=27.4932614555256, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786825, Length=381, Percent_Identity=25.1968503937008, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786552, Length=375, Percent_Identity=23.7333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081918, Length=325, Percent_Identity=25.5384615384615, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790718, Length=280, Percent_Identity=24.6428571428571, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=273, Percent_Identity=31.1355311355311, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562878, Length=251, Percent_Identity=30.2788844621514, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71988145, Length=341, Percent_Identity=25.2199413489736, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=367, Percent_Identity=25.8855585831063, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146526, Length=371, Percent_Identity=21.5633423180593, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997431, Length=373, Percent_Identity=21.4477211796247, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565904, Length=306, Percent_Identity=22.5490196078431, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=296, Percent_Identity=25.6756756756757, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319955, Length=326, Percent_Identity=28.8343558282209, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322619, Length=326, Percent_Identity=28.8343558282209, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323099, Length=339, Percent_Identity=26.2536873156342, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319257, Length=342, Percent_Identity=23.9766081871345, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=22.1917808219178, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=260, Percent_Identity=26.9230769230769, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=326, Percent_Identity=25.7668711656442, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=305, Percent_Identity=24.5901639344262, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=261, Percent_Identity=22.9885057471264, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=258, Percent_Identity=24.031007751938, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137530, Length=355, Percent_Identity=26.7605633802817, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17737895, Length=367, Percent_Identity=23.7057220708447, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17737897, Length=356, Percent_Identity=26.9662921348315, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI45550770, Length=338, Percent_Identity=24.8520710059172, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221457811, Length=338, Percent_Identity=24.8520710059172, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45551930, Length=338, Percent_Identity=24.8520710059172, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 37932; Mature: 37801

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKMLAAYLPGNATAELREVDIPQPGIGQVLIKMKSSGICGSDIHYIYHQHRGTAAAPDQ
CCCEEEEECCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCC
PLYRGFINGHEPCGQIVALGAGCRHFRESDRVLVYHISGCGFCSNCRRGYPISCTGVGKA
HHHHHHCCCCCCCCHHEEECCCHHHHCCCCCEEEEEECCCCCHHHCCCCCCEEEECCCCC
AYGWQRDGGHADYLLAEEKDLIHLPDSLSYEDGAFISCGVGTAYEGIVRGEVSGSDHVLV
CCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCEEEECCCCHHCCEEEEECCCCCCEEE
VGLGPVGMMAMMLAKGRGAKTVIGVDVIPERLATAKRLGLMDHGFLSGDDVTERIRQLTA
EECCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
GGANVTLDCSGNAKGRLLALQASSDWGRVIYIGETGKVEFEVSADLMHHQRRIIGSWVTS
CCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LHHMEKCCTDLHDWKMHPHQAITHRFKLGQAAEAYALMASGQCGKVVINFAD
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECC
>Mature Secondary Structure 
GKMLAAYLPGNATAELREVDIPQPGIGQVLIKMKSSGICGSDIHYIYHQHRGTAAAPDQ
CCEEEEECCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCHHEEEEECCCCCCCCCC
PLYRGFINGHEPCGQIVALGAGCRHFRESDRVLVYHISGCGFCSNCRRGYPISCTGVGKA
HHHHHHCCCCCCCCHHEEECCCHHHHCCCCCEEEEEECCCCCHHHCCCCCCEEEECCCCC
AYGWQRDGGHADYLLAEEKDLIHLPDSLSYEDGAFISCGVGTAYEGIVRGEVSGSDHVLV
CCCCCCCCCCEEEEEECCCCEEECCCCCCCCCCCEEEECCCCHHCCEEEEECCCCCCEEE
VGLGPVGMMAMMLAKGRGAKTVIGVDVIPERLATAKRLGLMDHGFLSGDDVTERIRQLTA
EECCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHC
GGANVTLDCSGNAKGRLLALQASSDWGRVIYIGETGKVEFEVSADLMHHQRRIIGSWVTS
CCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LHHMEKCCTDLHDWKMHPHQAITHRFKLGQAAEAYALMASGQCGKVVINFAD
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]