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The map label for this gene is abgR [H]

Identifier: 157372432

GI number: 157372432

Start: 4654357

End: 4655253

Strand: Reverse

Name: abgR [H]

Synonym: Spro_4199

Alternate gene names: 157372432

Gene position: 4655253-4654357 (Counterclockwise)

Preceding gene: 157372441

Following gene: 157372424

Centisome position: 85.44

GC content: 58.31

Gene sequence:

>897_bases
ATGCCAGCCTCAATAAAATTGCACCAATTACGTGCGTTTGTAGAAGTCAGCCGTCAGGGCAGTATTCGCGCCGCCAGCCG
GACTTCACAGCTTTCGCAGCCTGCGCTGACCAAGTCGATTCAGGAGCTGGAGACGGTGCTGGGGGCCAAGCTGTTTATCC
GCCGTAGCCAGGGCGTGGTGCTGACCGACTGCGGCGATAACTTTTTCCAGCATGCCAGCCTGATCCTCGAAGAGCTGCGG
GTGGCGCAGGAGGATATCCAGCAACGGCTGGGGCTGGCGGGCGGCTCGGTGAATATCGGCGTCGGCGGCAGCATTGCGCG
CACCGTGATGCCGCAGGTGATTAATCAGTTCCACCGTGAATATCCAAAGGTCAAAGTGCGGATTGTCGAAGGGCAACTGG
TGTCGATGATCCCGGAACTTCGCCAGGGTGAACTGGATTTCACGGTCAATACCTATTACCCCAGCAGCCTGGACAATGAA
TTGCAGTACGAACGGCTGATGGAGAAAGAGTACAAGGTGGTGGTGCGCAAGGGGCATCCGATGGAGGGGGCGACGTCACT
CAGGCAACTGCAGCACTGCGACTGGACCATGCCGACGCCAAAGGGCAGCTACTACCGGCTACTGCACGACTTGTTCGGGG
ATTTGGGAATGGCGCCGTCTATCAGCGTCACCTGCGAGACTTTTATGGCCTGCACCAGCCTGGTGGCGCAGAGCGACTTT
GTCAGCATTCTGTCGGTAGATGTGATCTCCGACCCGATATTGGGTAAACATCTGGTGCCGCTGGCGCTGGAGGAGAGCCT
GCCAAAAGCGACGTTTTATCTGATCCAGCGTAAAGACACCACGCTGACGCCGATGGGCGCACACCTGGCGCGCCTGTTCC
GCTTGTACTGCCGCTAA

Upstream 100 bases:

>100_bases
GGTTATTTATTATGTTTTTTTCGAATGTACACAATGGAATCGGGCTAAATAAGATGCCAATATCTTGCTATTGATAAACA
ACGGTTATCACCATTCGCCT

Downstream 100 bases:

>100_bases
AGGGAATTCTCCTTTCGAACACCCTGCACGGAAATCTCAGGCTTTACCCATTAACGGATCGCTGACGCTGTGGTCGCCGT
TCTCCAGCCGGCCTGCCAGT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPASIKLHQLRAFVEVSRQGSIRAASRTSQLSQPALTKSIQELETVLGAKLFIRRSQGVVLTDCGDNFFQHASLILEELR
VAQEDIQQRLGLAGGSVNIGVGGSIARTVMPQVINQFHREYPKVKVRIVEGQLVSMIPELRQGELDFTVNTYYPSSLDNE
LQYERLMEKEYKVVVRKGHPMEGATSLRQLQHCDWTMPTPKGSYYRLLHDLFGDLGMAPSISVTCETFMACTSLVAQSDF
VSILSVDVISDPILGKHLVPLALEESLPKATFYLIQRKDTTLTPMGAHLARLFRLYCR

Sequences:

>Translated_298_residues
MPASIKLHQLRAFVEVSRQGSIRAASRTSQLSQPALTKSIQELETVLGAKLFIRRSQGVVLTDCGDNFFQHASLILEELR
VAQEDIQQRLGLAGGSVNIGVGGSIARTVMPQVINQFHREYPKVKVRIVEGQLVSMIPELRQGELDFTVNTYYPSSLDNE
LQYERLMEKEYKVVVRKGHPMEGATSLRQLQHCDWTMPTPKGSYYRLLHDLFGDLGMAPSISVTCETFMACTSLVAQSDF
VSILSVDVISDPILGKHLVPLALEESLPKATFYLIQRKDTTLTPMGAHLARLFRLYCR
>Mature_297_residues
PASIKLHQLRAFVEVSRQGSIRAASRTSQLSQPALTKSIQELETVLGAKLFIRRSQGVVLTDCGDNFFQHASLILEELRV
AQEDIQQRLGLAGGSVNIGVGGSIARTVMPQVINQFHREYPKVKVRIVEGQLVSMIPELRQGELDFTVNTYYPSSLDNEL
QYERLMEKEYKVVVRKGHPMEGATSLRQLQHCDWTMPTPKGSYYRLLHDLFGDLGMAPSISVTCETFMACTSLVAQSDFV
SILSVDVISDPILGKHLVPLALEESLPKATFYLIQRKDTTLTPMGAHLARLFRLYCR

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=297, Percent_Identity=58.9225589225589, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1789506, Length=298, Percent_Identity=29.1946308724832, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87081904, Length=284, Percent_Identity=29.9295774647887, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI157672245, Length=275, Percent_Identity=24.3636363636364, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=25.8823529411765, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=176, Percent_Identity=24.4318181818182, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790399, Length=145, Percent_Identity=26.8965517241379, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=305, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790262, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=293, Percent_Identity=24.9146757679181, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=143, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367136, Length=141, Percent_Identity=34.7517730496454, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787128, Length=139, Percent_Identity=27.3381294964029, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=27.3972602739726, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=23.7354085603113, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=26.984126984127, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789440, Length=140, Percent_Identity=29.2857142857143, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1790208, Length=278, Percent_Identity=23.021582733813, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33366; Mature: 33235

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASIKLHQLRAFVEVSRQGSIRAASRTSQLSQPALTKSIQELETVLGAKLFIRRSQGVV
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCEE
LTDCGDNFFQHASLILEELRVAQEDIQQRLGLAGGSVNIGVGGSIARTVMPQVINQFHRE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
YPKVKVRIVEGQLVSMIPELRQGELDFTVNTYYPSSLDNELQYERLMEKEYKVVVRKGHP
CCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
MEGATSLRQLQHCDWTMPTPKGSYYRLLHDLFGDLGMAPSISVTCETFMACTSLVAQSDF
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VSILSVDVISDPILGKHLVPLALEESLPKATFYLIQRKDTTLTPMGAHLARLFRLYCR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PASIKLHQLRAFVEVSRQGSIRAASRTSQLSQPALTKSIQELETVLGAKLFIRRSQGVV
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCCEE
LTDCGDNFFQHASLILEELRVAQEDIQQRLGLAGGSVNIGVGGSIARTVMPQVINQFHRE
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
YPKVKVRIVEGQLVSMIPELRQGELDFTVNTYYPSSLDNELQYERLMEKEYKVVVRKGHP
CCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
MEGATSLRQLQHCDWTMPTPKGSYYRLLHDLFGDLGMAPSISVTCETFMACTSLVAQSDF
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VSILSVDVISDPILGKHLVPLALEESLPKATFYLIQRKDTTLTPMGAHLARLFRLYCR
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]