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The map label for this gene is yfcS [H]

Identifier: 157372378

GI number: 157372378

Start: 4597920

End: 4598675

Strand: Reverse

Name: yfcS [H]

Synonym: Spro_4145

Alternate gene names: 157372378

Gene position: 4598675-4597920 (Counterclockwise)

Preceding gene: 157372379

Following gene: 157372377

Centisome position: 84.4

GC content: 52.78

Gene sequence:

>756_bases
ATGAAAATGAACAAGATTTTGCCCCTTTCCGCGTTGTTGTTGTGCACGGGAATGACGGCTCAACAGGCAAACGCTGCGAT
TTCGCTGGACCGCACCCGGATCGTATTTAACGGCGGGGAAAAATCACAGAGTCTGACGGTGAGTAACCAGAACAAACAGT
TGCCCTATTTGGCTCAGGGTTGGATTGAAGATACCCAAGGCAATAAAATCCAGACCCCGCTGACTATTTTGCCGCCGGTA
CAACGCATTGAACCGGGCGCACAGAGCCAGATTAAAATTCAGGCTCTGCCGGGTGCCAATTTGTTGGCGCAAGACCGGGA
ATCGCTGTTTTATTTCAACCTGCGGGAAATTCCTCCGAAGAGCGATAAACCCAATACTTTGCAAATAGCCTTGCAAACGC
GCATCAAGCTTTTTTACCGGCCGGCGTCGATTGTGCCGACCAAAACGCAGATGGCTGCCCCATGGCAGGAAAAGCTGACG
CTGACACGTCAGGGCGACAGCTATCAACTGAACAACCCGACGCCGTACTTTATCACGTTGGTGGATGCGGGCAGCAAACC
GAATGCTGAAGGTGTTAAGGGCTTTGAACCGGTGATGGTACCGCCGAAAGGCCAAGCGCCGTTGGGGGTGAATGCCGGTG
TGTTGGGTGCCAATCCAGTTCTGACCTACATCAACGACTACGGTGGTCGTCCACAGCTGAAATTCACCTGCAGCGGCACT
ACCTGTAGCGCCACGCCGGTCAAAGATAGCAAATAA

Upstream 100 bases:

>100_bases
GTGAGATTTCTTTGCCGGAGACGCTGCCACAGAGTGACCAAACGAATTTATTGCTGCCGTGTAGTGCGGTGGCGACTACA
GAGAAAACAGGTAACGAATC

Downstream 100 bases:

>100_bases
ATCGATGTGAACGGCTGAGCGCATGCCTTTGCAAGGAGGGAAAGATGAGACAACAAAACAAAACTGTGTGCCTGCCGCCG
TCACGCCATGAGCGGCTGTA

Product: pili assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKMNKILPLSALLLCTGMTAQQANAAISLDRTRIVFNGGEKSQSLTVSNQNKQLPYLAQGWIEDTQGNKIQTPLTILPPV
QRIEPGAQSQIKIQALPGANLLAQDRESLFYFNLREIPPKSDKPNTLQIALQTRIKLFYRPASIVPTKTQMAAPWQEKLT
LTRQGDSYQLNNPTPYFITLVDAGSKPNAEGVKGFEPVMVPPKGQAPLGVNAGVLGANPVLTYINDYGGRPQLKFTCSGT
TCSATPVKDSK

Sequences:

>Translated_251_residues
MKMNKILPLSALLLCTGMTAQQANAAISLDRTRIVFNGGEKSQSLTVSNQNKQLPYLAQGWIEDTQGNKIQTPLTILPPV
QRIEPGAQSQIKIQALPGANLLAQDRESLFYFNLREIPPKSDKPNTLQIALQTRIKLFYRPASIVPTKTQMAAPWQEKLT
LTRQGDSYQLNNPTPYFITLVDAGSKPNAEGVKGFEPVMVPPKGQAPLGVNAGVLGANPVLTYINDYGGRPQLKFTCSGT
TCSATPVKDSK
>Mature_251_residues
MKMNKILPLSALLLCTGMTAQQANAAISLDRTRIVFNGGEKSQSLTVSNQNKQLPYLAQGWIEDTQGNKIQTPLTILPPV
QRIEPGAQSQIKIQALPGANLLAQDRESLFYFNLREIPPKSDKPNTLQIALQTRIKLFYRPASIVPTKTQMAAPWQEKLT
LTRQGDSYQLNNPTPYFITLVDAGSKPNAEGVKGFEPVMVPPKGQAPLGVNAGVLGANPVLTYINDYGGRPQLKFTCSGT
TCSATPVKDSK

Specific function: Could be required for the biogenesis of a putative fimbria [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1788677, Length=216, Percent_Identity=53.2407407407407, Blast_Score=251, Evalue=3e-68,
Organism=Escherichia coli, GI1786936, Length=244, Percent_Identity=40.9836065573771, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI87082203, Length=236, Percent_Identity=38.135593220339, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790771, Length=221, Percent_Identity=33.9366515837104, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789532, Length=222, Percent_Identity=34.6846846846847, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787171, Length=233, Percent_Identity=35.1931330472103, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788428, Length=214, Percent_Identity=33.6448598130841, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786333, Length=239, Percent_Identity=31.7991631799163, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786743, Length=229, Percent_Identity=29.2576419213974, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87081806, Length=234, Percent_Identity=24.7863247863248, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27335; Mature: 27335

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNKILPLSALLLCTGMTAQQANAAISLDRTRIVFNGGEKSQSLTVSNQNKQLPYLAQG
CCCCCCCCHHHHHHHCCCCHHHCCEEEEECCEEEEEECCCCCCEEEEECCCCCCCHHHHC
WIEDTQGNKIQTPLTILPPVQRIEPGAQSQIKIQALPGANLLAQDRESLFYFNLREIPPK
CEECCCCCEEECCEEECCCHHHCCCCCCCEEEEEECCCCCHHHCCCCEEEEEEEECCCCC
SDKPNTLQIALQTRIKLFYRPASIVPTKTQMAAPWQEKLTLTRQGDSYQLNNPTPYFITL
CCCCCEEEEEEEEEEEEEECCCCCCCCCHHHCCCHHHHEEEEECCCCEEECCCCCEEEEE
VDAGSKPNAEGVKGFEPVMVPPKGQAPLGVNAGVLGANPVLTYINDYGGRPQLKFTCSGT
EECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCEEEEEECCCCCCEEEEEECCC
TCSATPVKDSK
EECCCCCCCCC
>Mature Secondary Structure
MKMNKILPLSALLLCTGMTAQQANAAISLDRTRIVFNGGEKSQSLTVSNQNKQLPYLAQG
CCCCCCCCHHHHHHHCCCCHHHCCEEEEECCEEEEEECCCCCCEEEEECCCCCCCHHHHC
WIEDTQGNKIQTPLTILPPVQRIEPGAQSQIKIQALPGANLLAQDRESLFYFNLREIPPK
CEECCCCCEEECCEEECCCHHHCCCCCCCEEEEEECCCCCHHHCCCCEEEEEEEECCCCC
SDKPNTLQIALQTRIKLFYRPASIVPTKTQMAAPWQEKLTLTRQGDSYQLNNPTPYFITL
CCCCCEEEEEEEEEEEEEECCCCCCCCCHHHCCCHHHHEEEEECCCCEEECCCCCEEEEE
VDAGSKPNAEGVKGFEPVMVPPKGQAPLGVNAGVLGANPVLTYINDYGGRPQLKFTCSGT
EECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCEEEEEECCCCCCEEEEEECCC
TCSATPVKDSK
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]